Thermo Fisher Scientific Inc., (NYSE: TMO), the world leader in serving science, strengthened its industry-leading analytical instruments platform with innovative systems designed to help pharmaceutical and biologics producers more efficiently discover and develop candidate drugs.

“The success of our innovation strategy is based on continuous collaboration with our customers,” said Marc N. Casper, president and chief executive officer Thermo Fisher Scientific. “Our mission is to enable our customers to make the world healthier, cleaner and safer, and we are committed to providing them with the most advanced analytical technologies to help them facilitate research and accelerate discovery. This year’s ASMS showing is another great example of how we continue to leverage our technology leadership to raise the performance bar and help our customers achieve their goals.”

The new Thermo Scientific Q Exactive BioPharma MS/MS Hybrid Quadropole-Orbitrap mass spectrometer takes full advantage of the high-resolution, accurate-mass (HRAM) capabilities of the Orbitrap mass analyzer to enable key workflows for protein characterization in a single instrument. Combined with recommended sample preparation and analysis methods using Thermo Scientific reagents, columns, UHPLC and data processing technologies, the Q Exactive BioPharma system provides a comprehensive solution for customers performing biopharmaceutical characterization.

At ASMS, Thermo Fisher also featured its new Thermo Scientific Vanquish Flex Binary UHPLC system, an ideal complement for pharmaceutical and biopharmaceutical laboratories performing qualitative and quantitative LC or LC-MS analysis. Built for high-speed and fast gradient applications, the Vanquish platform delivers outstanding reproducibility. 

As part of its focus on innovation, Thermo Fisher featured new technology from 908 Devices, a pioneer in purpose-built analytical devices for chemical analysis. Customers using Thermo Fisher’s mass spectrometers can now incorporate 908 Devices’ breakthrough ZipChip microfluidics separation technology to deliver fast, high-quality separations that transform analysis of biomolecules.

Thermo Fisher also showcased high-profile collaborations through presentations and posters by notable scientists doing breakthrough work with its mass spectrometry technologies.

• Dr. Willi Haas, assistant professor at Harvard Medical School, presented the Advances in Accurate, High-Throughput Quantitative Proteomics Breakfast Workshop. His approach combines Orbitrap HRAM MS and synchronous precursor selection (SPS)-based MS3 technology on the Thermo Scientific Orbitrap Tribrid MS systemtoaccurately measure the smallest changes in low-abundance proteins. 
• Dr. Fan Liu from the Albert Heck Lab, Utrecht University, Netherlands, presented the Improved Workflows for Structural Proteomics Breakfast Workshop. Dr. Liu’s lab is using Orbitrap technology for proteome-wide cross-linking mass spectrometry to chart the cellular interactome, the whole set of molecular interactions in a single cell.
• Dr. Jennifer Abelin from the Eli and Edythe L. Broad Institute of MIT and Harvard presented High-throughput Profiling of HLA Allele-specific Peptides by MS for Improved Epitope Predictionsat the Thermo Fisher Annual User Meeting. She willdiscuss her use of LC-MS/MS techniques to improve the understanding of antigen processing to identify peptides in diseases including cancer, inflammatory bowel disease and infectious diseases.
• Dr. Akhilesh Pandey, John Hopkins University School of Medicine, presented Getting Ready for Clinical Proteomics at the Thermo Fisher Annual User Meeting. Dr. Pandey will discuss the emerging use of proteomics in a clinical setting. Dr. Pandey is best known for his groundbreaking research in the mapping of the human proteome http://www.humanproteomemap.org.

Finally, Thermo Fisher recognized the winners of the 2016 Thermo Scientific Tandem Mass Tag (TMT) Research Awards, an international research grant for scientists and their work in proteomics.

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