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New Malvern web resource goes straight to the point for OINDP

MAL JOB 2074_Image.jpgWith the continuing focus on OINDPs (orally inhaled and nasal drug products) as effective delivery vehicles for a wide variety of therapeutics, Malvern Instruments has established a new gateway within its website that guides visitors directly to technical information, downloadable application notes, case studies and interactive presentations on particle size measurement for this class of product. Upon entering, visitors can choose to go directly to information on particle sizing in nasal sprays, inhalers or nebulisers. The access point is  

For all OINDPs, particle size is a critical-to-quality attribute, directly influencing clinical efficacy. Malvern's Spraytec system is widely used in their analysis, from early development right through to manufacturing and quality control. This advanced laser diffraction particle size analyzer is designed specifically for spraydroplet and dry powder aerosol measurements. A robust system with SOP-driven operation it offers: rapid data acquisition for real-time monitoring of particle size changes during a spray event; a broad dynamic range from 0.1 to 2000 micron, covering the sub-10 micron range of primary interest for pulmonary delivery, nasal sprays and the characterization of poorly dispersed agglomerates; and concentration measurement, which in combination with size data, enables the dynamic study of dispersion behaviour.  

A powerful tool for rapid screening and accelerated optimization of OINDPs, Spraytec complements techniques such as cascade impaction, adding detailed insight into dispersion and atomisation behaviour. Such information promotes an efficient, knowledge-led approach to device and formulation development, as advocated by QbD. 

Find out more at



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