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HPLC & Automated Tablet Dissolution Testing Come Together

publication date: Jun 14, 2012
author/source: Gilson

The Gilson 241 Automated Double Dissolution System (ADDS)

The Gilson 241 Automated Double Dissolution System (ADDS) was developed with a Major Pharmaceutical company to address the growing need for increased dissolution testing by HPLC. The system controls the sampling and HPLC analysis of active drug components in dissolution media.

With the Gilson system, the dissolution media is circulated in a closed loop system by means of a Gilson Minipuls peristaltic pump and samples are taken at the specified time intervals through the use of an innovative flow-through HPLC vial.

The ADDS software controls the whole process from taking samples from the baths to injecting the samples onto ANY HPLC or UHPLC system. Samples can also be transferred into sealed HPLC vials for storage or processing at a later date.  

There are 5 different pre-program methods. Sample lists can be imported from other software data packages or created by the user. Standards and samples can be run together in bracketed sample lists. Dedicated system suitability and cleaning protocols are available

The system is designed on Gilson's tried and tested liquid handling platform and comes complete, with the Gilson 241 liquid handler, software, racks and sample pumps.

Gilson in the UK offers complete sales, support and service for all Gilson Pipetman® pipettes and liquid handling products in the UK and Ireland. 

Visit or call 0845 5196 872 for more information.

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