Innovative batch and flow reactors from leading manufacturer Syrris are proving advantageous for a variety of nanoparticle applications, offering scientists working in the field numerous benefits.

Simple to assemble with no tools required, the easy-to-use reactors enable conditions such as temperature, time, mixing, reagent ratios and concentrations to be quickly varied for rapid process optimization. Excellent mixing and temperature control ensure a narrow particle size distribution and, to further enhance reproducibility, the systems can be fully automated.

Batch reactors such as the modular Atlas system offer multiple sensors including temperature, pH and turbidity, and have no particle size restrictions. With a large choice of reactor sizes, process scale-up is straightforward. One company successfully performing batch synthesis of nanoparticles is Spanish nanomedicine company Midatech Biogune. “Our Atlas Potassium reactors have allowed us to scale-up production, enabling variables such as pH and temperature to be tightly controlled,” said CEO Justin Barry. Flow chemists have enjoyed similar success, with Paulina Lloret, a researcher at the Argentinian National Institute of Industrial Technologies, saying, “We trialed our nanoparticle experiments on the Asia flow chemistry system, and immediately placed an order for our own system to optimize the speed and results of our synthesis workflow”. The flexible Asia system’s fast and reproducible mixing, excellent heat transfer and accurate temperature control, plus a wide range of flow rates, allow process optimization and production on the same reactor. This high level of control has enabled synthesis of nanoparticles not previously seen using batch techniques.

Syrris Limited

Syrris is world renowned for excellence in chemical reactor systems and is a world leader in flow chemistry systems. Established in 2001, Syrris employs over 30 scientists and engineers at its facility in Royston (near Cambridge, UK) and has offices in the US, Japan, India and Brazil plus over 30 distributors worldwide.

Syrris develops laboratory automation products for research and development chemists in industries such as pharma, petrochem, agrochem, fine chemical synthesis etc. as well as academia. Syrris products are used in a wide variety of applications and laboratories including process, discovery, crystallization, process safety, scale-up and many more.

Syrris products include the innovative range of fully automated batch reactor products (Atlas), a manually operated jacketed reactor platform (Globe) and flow chemistry systems (Asia and Africa). In recognition of its technological achievements, Syrris has been awarded the “Eastern Region’s UKTI Best Established Exporter” and the “Most Outstanding Export Achievement” at the Global Opportunity Conference on International Trade. Syrris’ Asia Flow Chemistry system was the recipient of a prestigious 2012 R&D award.

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