Uniqsis has published details of a mild nitration method using its FlowSyn flow chemistry system that enables short reaction times and high conversion to be achieved whilst minimising the amount of corrosive (and potentially explosive) hot nitrating mixture present in the reactor at any one time.
Nitration is an important synthetic procedure that is often difficult to control. Under continuous flow-through conditions, however, exotherms are typically well controlled and nitration can be safely performed on a large scale. Using Uniqsis’s proprietary glass static mixer/reactor chip technology - nitration can be safely performed under accelerated conditions at elevated temperature and pressure without the associated problems typically encountered in batch reactors of controlling latency periods or controlling thermal run away...
Thermo Fisher Scientific is pleased to announce a new technical note on fast separations in a carbonated beverage using increased flow rates on our high-pressure capillary Ion Chromatography (IC) system, the Thermo Scientific Dionex ICS-5000+ Reagent Free HPIC system.
Technical Note 118: Fast Separations of Anions and Organic Acids in a Carbonated Beverage Using High-Pressure Capillary IC describes the determinations of organic acids in these carbonated beverages. The beverage industry uses these acidulants and flavoring agents to maintain beverage freshness, to minimize microbiological growth and to add a characteristic flavor...
Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, has produced a new, free-to-download whitepaper titled ‘When to use targeted resequencing — Choosing the right NGS method.’ The paper aims to assist researchers when planning NGS strategies by providing a detailed review of the major resequencing methods. Comparing and contrasting method suitability, the paper also examines the significant impact of data analysis, as well as time and cost considerations...
Thermo Fisher Scientific has developed a high-performance liquid chromatography (HPLC) method for a fast and sensitive determination of paraquat and diquat in tap and environmental water samples.
This approach uses on-line solid phase extraction (SPE) and achieves method detection limits that meet the requirements of both U.S. Environmental Protection Agency Method 549.2 and European Union 98/83/EC. Application Note (AN) 1051: Sensitive and Rapid Determination of Paraquat and Diquat in Tap and Environmental Water demonstrates use of a mixed-mode column to provide sufficient retention, excellent resolution, and good peak shape for these herbicides...
Multi-mode microplate readers are an indispensable laboratory instrument that enable many applications to be performed on multiple samples.
Life science applications involving cells are increasingly desired due to higher biological relevance associated with functional readouts. Microplate readers can provide quantification of a specific target, such as a protein or its post-translational modification, or phenotypes such as cell death through apoptosis or necrosis. Quantification is provided relative to assay controls and/or standards using dispersive optical detection and light collection with photomultiplier tubes (PMT)...
Xmark Media the organisers of Photonex 2013, the UK's showcase photonics conference & exhibition announce the programme and speakers for the meeting on Nano and Bio-Imaging. This FREE-to-attend conference will be held on Wednesday 16th October as part of a diverse two-day event at the visitor-friendly Ricoh Arena in Coventry.
Significant advances in the development of optical techniques have led to an inter-disciplinary use of photonics in the study of various problems in the life sciences, in biological and chemical sciences, in medicine, clinical sciences, neurophysiology etc. Researchers are continually looking for better ways to analyse complex processes....
Thermo Fisher Scientific is pleased to announce a new technical note discussing rapid separation of inorganic cations in municipal wastewater using our high pressure capillary Ion Chromatography system, the Thermo Scientific Dionex 5000+ ICS HPIC system.
Technical Note 121: Fast Determinations of Inorganic Cations in Municipal Wastewater Using High-Pressure Capillary IC demonstrates how the separation of inorganic cations are important to municipal drinking water and wastewater treatment plants for compliance monitoring. Cationic determinations are necessary as part of the water monitoring program’s secondary water specification of acceptable taste....
METTLER TOLEDO is pleased to present a new white paper to help those working in the Chemical, Food, Consumer Product, and Mineral industries meet the challenge of understanding, optimizing and controlling particle and droplet systems in a variety of applications including suspensions, emulsions and crystallizations.
“Best Practice for Inline Particle Size Characterization” reviews a series of real-life examples where prominent food, chemical and consumer product companies have used inline characterization methods to measure real time particle size dynamics at full-process concentration to ensure repeatable process endpoints, improve yield, and optimize product quality. Inconsistencies in solid or liquid dispersion, agglomeration or precipitation can create variability in product stability and manufacturing throughput...
The Institute of Nanotechnology (IoN) will be the official charity partner of the largest international nanotechnology conference to take place in the UK.
Nano London 2014 will take place from 17th-19th June 2014 at Olympia in London, and brings together industry leaders, academics, manufacturers, suppliers and investors in the fast growing field of nanotechnology. The IoN is a registered charity which supports education and training within the nanotechnology community and provides industry and governments with intelligence on nanotechnology and its applications. The Institute has a global network of members and is highly active in European research programmes such as FP7...
Thermo Fisher Scientific is pleased to announce a new technical note on the fast separations of inorganic ions in saline solution samples.
TN 130: Fast Determinations in Salton Sea Samples Using a High-Pressure IC System demonstrates fast separations of inorganic anions and cations in a Salton Sea surface water sample and a neighboring municipal drinking water sample using ion-exchange chromatography. Monitoring salinity levels in estuarine ecosystems is critical to preventing salinity-specific diseases...
Anasys Instruments reports on the recent publication from the University of Illinois which describes the development of a novel technique for chemical identification at the nanometer scale based on AFM-IR. The work is described in a paper published in the Review of Scientific Instruments 84.
For more than 20 years, researchers have been using atomic force microscopy (AFM) to measure and characterize materials at the nanometer scale. However AFM-based measurements of chemistry and chemical properties of materials were generally not possible, until now...
New Customer Application Note Available from Wyatt Technology
Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation and software, publishes new application note highlighting a study made by Florida State University. Authored by Tsz Kin Martin Tsui, Claudius Mundoma and Hong Li from Florida State University, the paper showcases how the Wyatt DynaPro dynamic light scattering (DLS) system can be used to characterize homogeneity and stability of a heterodimeric protein complex (HPC) under various buffer conditions. The results demonstrate that the pH of the buffer solutions influences the sample homogeneity and stability...
PREP 2014: 27th International Symposium, Exhibits and Workshops on Preparative and Process Chromatography, Ion Exchange, Adsorption Processes and Related Separation Techniques
Save the dates! PREP 2014 July 20 - 23, 2014 Boston, MA, USA. Premier arena for the presentation and discussion of the latest developments in Preparative and Process Chromatography, Separation Science and Technology. PREP 2014 is where scientists, engineers, and suppliers of media, equipment, and technology from around the world come to focus on the cutting-edge areas of preparative and process chromatography, to learn how to solve today's practical problems, and to prepare for the future...
Recognising Technology’s Novel Method of Improving Liquid Handling Efficiency
Redd&Whyte, an expert supplier of liquid handling automation for drug discovery and life science research applications, is delighted to announce its innovative Preddator low-volume microplate dispenser has been awarded the “ELRIG Technology Prize”, which recognises the most interesting automation seen at the recent ELRIG Robotics and Automation Conference...
The European Society for Translational Medicine (EUSTM) is a global non-profit neutral platform for the advancement and progress of Translational Medicine.
Translational medicine has gained significant attention from academia, funding bodies, health care policy makers as well as pharma and biotech industry due to its promise to enhance overall quality of global health care. The society's goal is to facilitate research and development of novel and affordable diagnostic tools and treatments for clinical disorders affecting global population...
Nanotechnology conference secures new backers for next year’s event
Nano London 2014, a conference and exhibition for the international nanotechnology industry, is heading confidently towards next year’s event after securing further investment and adding to its list of key industry partnerships. The conference will assemble the leading thinkers and players in the nanotechnology field, and serve as a platform for education, communication, collaboration and innovation...
Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, has produced a new, free-to-download application note on combined array comparative genomic hybridisation (aCGH) and single nucleotide polymorphism (SNP) arrays.
The application note, titled ‘Detecting copy number variants and runs of homozygosity on a single array — challenges and applications’ aims to support researchers in navigating this combined approach for the simultaneous detection of copy number variations (CNVs) and runs of homozygosity (ROH). aCGH has established itself as the “gold-standard” platform for array-based CNV detection. Recent advances have enabled the combination of aCGH probes for CNV detection with probes able to detect SNPs...
Drawing upon many years’ experience of designing and supplying liquid flowmeters to meet stringent OEM specifications - Titan Enterprises has produced an informative white paper 'How to specify liquid flowmeters'.
Accurate, reliable, cost effective flow measurement is more important today than it has ever been. However the optimal liquid flowmeter varies considerably according to a wide range of operational parameters including pipe bore, flow path, liquid viscosity, particulate levels, measurement accuracy, measurement dynamic range, maintenance and target purchase price...
New website designed as an easy point of reference for Stomacher® applications and protocols
Seward Limited, founding manufacturer and developer of the world leading, patented Stomacher® Laboratory Paddle Blender range, has launched a new, fully refreshed website. This is designed as a readily accessible point of reference for customers seeking assistance in sample preparation for microbiological analysis in the food, life science and environmental sectors. New to the Seward website includes a Resource Centre to help visitors identify how the Stomacher® may be used. In addition, user guides and technical data are available for download, with useful videos demonstrating various routine protocols...
Nanounity announces the public launch of new characterization tools and techniques for the microscopy community. Products from Pemtron & Delmic will debut at the annual 2013 Microscopy & Microanalysis Conference & Exhibition to be held in Indianapolis, August 4-8. The company will be presenting exciting new products of manufacturers from the USA, Korea and Europe.
New instrumentation, tools and techniques, will be featured on the Nanounity booth, #828, at this year's annual M&M meeting being held in Indianapolis, August 4-8, 2013. The Pemtron SEMART™ PS-250 scanning electron microscope (SEM) will be making its Nanounity US debut. This intermediate microscope provides users with quick and easy operation offering high performance at a reasonable price, a level that a user might expect to pay at least twice to own. With the power of the PS-230, the PS250 allows users to work with larger samples up to 140 mm while retaining 3 nm spatial resolution. Users may add optional EBSD (Electron Detector Back Scattered) and EDS (Energy Dispersive Spectrometer) for more comprehensive analytical performance...
BBI Solutions, a world leader in immunoassay development and contract manufacturing, will launch its unique range of Recombinant Fab Monoclonal Antibodies on booth #3363 at the American Association for Clinical Chemistry’s (AACC) Annual Meeting and Clinical Lab Expo, on July 28-August 31, 2013, in Houston, Texas.
These matched antibodies pairs, developed using proprietary phage display selection and the Luminex platform, exhibit sub-nanomolar affinities, exceptional sensitivity, and provide assay developers with clinically relevant performance characteristics to 34 biomarkers, with more in development...
Porvair Sciences has announced an application note describing the excellent results achievable from a new 96-well format version of its ChromaTrap chromatin immunoprecipitation (ChIP) assay technology.
Developments in the field of epigenetics are rapidly expanding as researchers elucidate the principles governing gene regulation through the in vivo dynamic binding of proteins to DNA. Key to this is the need to analyse large numbers of high and low abundant regulatory mechanisms to systematically map protein-DNA interactions following pathogen/disease stimulus...
Significant advances in the development of optical techniques have led to an inter-disciplinary use of photonics in the study of various problems in the life sciences, in biological and chemical sciences, in medicine, clinical sciences, neurophysiology etc. Researchers are continually looking for better ways to analyse complex processes....
Technical Note 121: Fast Determinations of Inorganic Cations in Municipal Wastewater Using High-Pressure Capillary IC demonstrates how the separation of inorganic cations are important to municipal drinking water and wastewater treatment plants for compliance monitoring. Cationic determinations are necessary as part of the water monitoring program’s secondary water specification of acceptable taste....
“Best Practice for Inline Particle Size Characterization” reviews a series of real-life examples where prominent food, chemical and consumer product companies have used inline characterization methods to measure real time particle size dynamics at full-process concentration to ensure repeatable process endpoints, improve yield, and optimize product quality. Inconsistencies in solid or liquid dispersion, agglomeration or precipitation can create variability in product stability and manufacturing throughput...
Nano London 2014, a conference and exhibition for the international nanotechnology industry, is heading confidently towards next year’s event after securing further investment and adding to its list of key industry partnerships. The conference will assemble the leading thinkers and players in the nanotechnology field, and serve as a platform for education, communication, collaboration and innovation...
Accurate, reliable, cost effective flow measurement is more important today than it has ever been. However the optimal liquid flowmeter varies considerably according to a wide range of operational parameters including pipe bore, flow path, liquid viscosity, particulate levels, measurement accuracy, measurement dynamic range, maintenance and target purchase price...
Seward Limited, founding manufacturer and developer of the world leading, patented Stomacher® Laboratory Paddle Blender range, has launched a new, fully refreshed website. This is designed as a readily accessible point of reference for customers seeking assistance in sample preparation for microbiological analysis in the food, life science and environmental sectors. New to the Seward website includes a Resource Centre to help visitors identify how the Stomacher® may be used. In addition, user guides and technical data are available for download, with useful videos demonstrating various routine protocols...
New instrumentation, tools and techniques, will be featured on the Nanounity booth, #828, at this year's annual M&M meeting being held in Indianapolis, August 4-8, 2013. The Pemtron SEMART™ PS-250 scanning electron microscope (SEM) will be making its Nanounity US debut. This intermediate microscope provides users with quick and easy operation offering high performance at a reasonable price, a level that a user might expect to pay at least twice to own. With the power of the PS-230, the PS250 allows users to work with larger samples up to 140 mm while retaining 3 nm spatial resolution. Users may add optional EBSD (Electron Detector Back Scattered) and EDS (Energy Dispersive Spectrometer) for more comprehensive analytical performance...
These matched antibodies pairs, developed using proprietary phage display selection and the Luminex platform, exhibit sub-nanomolar affinities, exceptional sensitivity, and provide assay developers with clinically relevant performance characteristics to 34 biomarkers, with more in development...
Developments in the field of epigenetics are rapidly expanding as researchers elucidate the principles governing gene regulation through the in vivo dynamic binding of proteins to DNA. Key to this is the need to analyse large numbers of high and low abundant regulatory mechanisms to systematically map protein-DNA interactions following pathogen/disease stimulus...