Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their dynamic MDSG600 stage for geological research at the Geological Survey of Finland.
Founded in 1886, the Geological Survey of Finland (GTK) was created to promote the systematic and sustainable use of the Earth's resources through the production and dissemination of geological information to society. The GTK is Finland's national geoscientific information centre and it participates actively in international research and project work, with the areas of focus falling into three main categories: mineral resources and exploration; energy supply and environment; and land use and construction...
NanoSight announces that Particle Technology Labs, PTL, has established cGMP compliance for Nanoparticle Tracking Analysis, NTA, and this is now available on a contract basis to the pharmaceutical industry.
PTL is the leading particle characterization research and advisory company in the United States, providing assistance to a wide range of industries. Nanoparticle Tracking Analysis, NTA, has been adopted for both research-based projects and as a quality control tool for regulated industries. PTL’s NanoSight LM10-HSB instrument is certified cGMP as of June 4, 2013. cGMP refers to the Current Good Manufacturing Practice regulations enforced by the US Food and Drug Administration (FDA)...
With the introduction of the next generation Phenom ProX desktop SEM Phenom-World confirms its positions in the top of the high-end table top for SEM imaging and analysis.
With a magnification range up to 100,000x and resolution down to 17nm the Phenom ProX delivers more detailed information than ever before. All Phenom-World scanning electron microscopes are intuitive to use, compact, fast to create results and built to high quality standards. The most extended solution in the range is the next generation Phenom ProX. The advanced system identifies different elements in a specimen by using the integrated Element Identification software with a specially designed EDS detector. With new techniques and software-developments, the magnification range has been extended from max. 45,000x to 100,000x magnification. Combined with a resolution of 17nm, the next generation Phenom ProX is a valuable instrument for a wide variety of applications....
Leica DMC2900 for Brightfield, Leica DFC3000 G for Fluorescence Applications
As of June, Leica Microsystems has launched two cameras that are ideal instruments for routine brightfield or fluorescence applications. Both cameras are equipped with sensors dedicated to the respective applications that allow live images of up to 30 frames per second and a USB 3.0 interface for fast data transfer. The Leica Application Suite (LAS) and the fluorescence counterpart LAS Advanced Fluorescence (LAS AF) software platform provide for image acquisition and support users in analysis and documentation...
Expanding from light and electron microscopy into X-ray microscopy solutions
ZEISS, the international leader in the fields of optics and optoelectronics today announced the planned acquisition of the US-based Xradia, Inc. Xradia is an medium-size company providing innovative 3D X-ray microscopes for industrial and academic research applications. The closing of the transaction is subject to the fulfillment of customary closing conditions including a required filing with the U.S. competition authorities. After closing, Xradia, Inc. will operate under the new name Carl Zeiss X-ray Microscopy, Inc...
Event Date: June 27, 2013 at 12:00 PM Eastern Daylight Time
Multi-mode microplate readers are a useful tool for cell-based assays. These instruments use PMT-based optics to provide a cell population-averaged assay signal relative to assay controls that can quantify biomolecule expression, activation, inhibition and post-translational modulation. Fluorescence microscopy allows the analysis of sub-populations of cells or even analysis of a single cell, depending on the magnification used...
Read MoreAny Assay, Any Wavelength, Any Bandwidth with the New CLARIOstar High Performance Microplate ReaderJun 24, 2013
Any Assay, Any Wavelength, Any Bandwidth
Over the years, many different assays have been designed to work on many different microplate readers. As new techniques emerged, so did new microplate reader technology. The new CLARIOstar microplate reader from BMG LABTECH is the latest evolution in microplate reader instrumentation....
Olympus continues to expand the capabilities of its IX3 inverted microscope frames with the launch of cellVivo - a new, modular and flexible incubation system, including darkroom and laser-safety capabilities.
Fully adaptable for basic and high-end IX3 microscope systems alike, cellVivo offers precise control of environmental conditions, as well as user-friendly remote monitoring. Designed with the complete workflow in mind, Olympus has launched itscellVivo incubation system, for precise and ergonomic environmental control of advanced live cell imaging. Following the modular approach of the IX3 range of inverted microscope frames, cellVivo is based on a “one size fits all” concept, with adaptors for various IX73 and IX83 frame types, circumventing the need for multiple incubation systems for distinct microscope configurations...
FREE NanoSight Webinar on the use of Nanoparticle Tracking Analysis in Drug Delivery Research.
NanoSight, leading manufacturers of unique nanoparticle characterization technology, address the challenges of nanoparticle control and analysis in the latest of their popular webinar program. On Thursday 6th June, NanoSight hosted a webinar to look at how Nanoparticle Tracking Analysis (NTA) is used to as a characterization tool during the development of drug delivery systems. During the webinar NanoSight.....
FLIR Systems has announced the release of a new range of thermal imaging cameras optimised for industrial R&D applications including tyre / brake testing, on and through glass measurements, welding / soldering processes and fast moving process control applications.
FLIR A3500sc / A6500sc series thermal imaging cameras incorporate a cooled 3-5 micron MW-IR detector making R&D applications that need better image quality, more sensitivity and a higher frame rate routine. Achieving a high thermal sensitivity of <25 mK - FLIR A3500sc / A6500sc series cameras are able to capture the finest image details and temperature difference information. In addition, precise camera synchronization and triggering makes these cameras ideal for high-speed, high sensitivity applications...
The advanced Spectroline®Bi-O-Vision™ Series transilluminators feature two workstations, producing both 312nm ultraviolet and white light.
The TD-1000R model offers fixed-intensity while the TVD-1000R model offers variable-intensity control of either UV or white light. These units are continuously adjustable from 100% down to 50%. This enables life science researchers to select medium wavelength ultraviolet or white light illumination to view fluorescent gels or visible blots...
The all new Nikon SMZ25 and SMZ18 stereomicroscopes have evolved to meet the increasing needs for imaging systems that range from single cells to whole organisms. Featuring a large zoom ratio of 25:1 for the SMZ25, superior resolution and exceptional fluorescence transmission capability, the ergonomic, easy-to-use, fully motorised SMZ25 and manual SMZ18 are ideal for all bioscience applications....
Bruker Corporation today announced that it has signed an exclusive patent license agreement with 3M Company, which allows Bruker to include 3M patented innovations relating to matrix-assisted laser desorption ionization (MALDI) mass spectrometry imaging.
The licensed 3M patents are directed to a technique for performing mass spectrometry analysis on proteins in tissue that has been preserved in paraffin. The technology enables researchers to more easily study formalin-fixed, paraffin-embedded (FFPE) tissue for life-science research and drug development. MALDI imaging has been increasingly used to analyze clinically relevant tissues such as tumor biopsies. The molecular phenotypes observed by MALDI imaging have been shown to correlate with parameters such as disease status or patient outcome, and have been successfully applied to the classification of tissue samples.
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on the work of the Nano-Mechanics Laboratory at the Indian Institute of Science Education & Research (IISER) Pune, India.
The Nano-mechanics group develops and uses novel techniques to understand molecular processes and has recently developed new instrumentation in the fields of single molecule force spectroscopy and correlation spectroscopy. There are three main areas of research: protein folding using AFM, measuring the mechanical properties of supported lipid bilayers and following the mechanical response of nano-confined fluids. This last area is performed on home-built instruments....
Read MoreScientists at CENIMAT and the Materials Science Department, New University of Lisbon, are investigating LCP polymer blends using the Linkam CSS450Jun 12, 2013
Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their popular CSS450 stage for polymer research at the New University of Lisbon, Portugal.
Liquid-crystalline polymers (LCPs) are materials with exceptionally useful mechanical properties compared with ordinary industrial polymers. LCPs are not frequently used in industry due to their prohibitive production costs, but blending an LCP with a relatively common polymer is one way to utilize them at a reduced cost. Only blends that fibrillate in situ during processing, and when the fibrils maintain a solid state, do they demonstrate these superior properties...
Read MoreSyngene's G:BOX Chemi used in Microbial Research at Wageningen UR, The Netherlands to Contribute to Understanding how Bacterial Immune Systems FunctionJun 10, 2013
Syngene, a world-leading manufacturer of image analysis solutions is delighted to announce that one of its G:BOX Chemi imaging systems is being used at the Wageningen UR (University & Research centre) to visualise and analyse bacterial proteins as part of a research programme to understand the molecular mechanisms behind bacterial immune systems.
Scientists in the Laboratory of Microbiology at Wageningen UR are using a G:BOX Chemi system to accurately image both chemiluminescent and fluorescently labelled Western blots of multi-functional protein complexes belonging to the CRISPR/Cas proteins. These proteins degrade foreign DNA, thus protecting bacteria from infection and by studying them, the scientists hope to unravel how bacterial immune systems function. Determining pathways of bacterial immunity could lead to a number of applications, such as being able to immunise industrially important bacteria used in food production and large-scale fermentations against phage infection....
More speed and precision for in-process inspection
At the 2013 Control international trade fair for quality assurance, ZEISS presented its new Hardware Auto Focus and cleanroom kit for the proven Axio Imager Vario microscope system. An integratable autofocus system ensures fast and precise focusing. The Hardware Auto Focus is ideal for surface inspections on reflective, low-contrast samples. In transmitted and reflected light (brightfield, darkfield, polarization contrast and oblique illumination), the focus system ensures high precision down to 0.3 of the depth of field of the objective lens....
Hitachi High-Technologies has launched the TM3030, the third generation of its popular series of tabletop microscopes.
The TM3030 features improved electron optics to give better resolution and higher magnification capabilities together with built-in image processing to further enhance image quality. The improved electron-optical system of the TM3030 provides significantly better resolution, which is especially useful for the 5 kV mode of operation. Imaging at 5 kV reveals more surface detail and can be used for both topographic and elemental composition imaging. The new electron optics produce sharper images at higher magnifications across its three imaging and analysis modes....
CytationTM3 is a cell imaging multi-mode microplate reader that combines automated digital microscopy and conventional microplate detection.
This unique patent pending design provides rich phenotypic cellular information with well-based quantitative data. Equipped with BioTek’s patented Hybrid Technology™ for microplate detection, Cytation3 includes both high sensitivity filter-based detection and a flexible monochromator based system for unmatched versatility and performance. The upgradable fluorescence cellular imaging module provides researchers rich cellular visualization analysis without the complexity and expense of standard automated microscopes, making cell imaging more accessible to a larger number of research laboratories at an affordable price...
Read MoreNon-invasive Quality Control of Cryopreserved SamplesMay 23, 2013
Since the dawn of modern medicine, human biological material has been collected, stored, and used for a variety of purposes with biological integrity ensured by cryopreservation at temperatures below -137°C. These samples are almost always unique and irreplaceable but, until now, it has been impossible to quality assure the material before use to check that thermal damage has not occurred.
In a recently published paper, a team from Saarland University's Biophysics and Cryotechnology department in Germany has demonstrated a powerful, Raman-scattering technique for monitoring and investigating cryopreserved samples. In particular, they confirmed unambiguously the detection of ice crystals in vitreous samples in situ at temperatures below -120°C....
The Leica TCS SP8 X provides total freedom of excitation and emission coupled with low laser power and high sensitivity
The Department of Biology at New York University has been equipped with the 100th Leica TCS SP8 X, a state-of-the-art confocal laser scanning microscope with a white light laser. The system offers complete spectral freedom for fluorescence experiments. For live cell imaging, the combination of high sensitivity and low laser power provides better cell viability. The new instrument is installed in the Center for Developmental Genetics and has been used to further Assistant Professor Dr. Lionel Christiaen’s goal of understanding how tissue-specific gene regulatory networks control and coordinate cell behavior during morphogenesis since February 2013....
Read MoreEasy to use imaging and analysis with cellSens 1.8May 21, 2013
Olympus enhances its core cellSens life science imaging and analysis software with the release of version 1.8. New customisable interface and improved support for multi well plates enhance the user experience.
Focusing on ease of use for routine applications, the latest cellSens software release, version 1.8, offers flexible and user-centric imaging, processing, analysing and reporting. New and enhanced functions include a fully customisable user interface, precise frame-by-frame sample navigation and easy one-button switching between wells. For a wide range of life science applications, cellSens provides easy control of the workflow. The software binds together Olympus frames, cameras and high-quality optics to form complete, highly precise and user-friendly microscopy systems....
Founded in 1886, the Geological Survey of Finland (GTK) was created to promote the systematic and sustainable use of the Earth's resources through the production and dissemination of geological information to society. The GTK is Finland's national geoscientific information centre and it participates actively in international research and project work, with the areas of focus falling into three main categories: mineral resources and exploration; energy supply and environment; and land use and construction...
PTL is the leading particle characterization research and advisory company in the United States, providing assistance to a wide range of industries. Nanoparticle Tracking Analysis, NTA, has been adopted for both research-based projects and as a quality control tool for regulated industries. PTL’s NanoSight LM10-HSB instrument is certified cGMP as of June 4, 2013. cGMP refers to the Current Good Manufacturing Practice regulations enforced by the US Food and Drug Administration (FDA)...
With a magnification range up to 100,000x and resolution down to 17nm the Phenom ProX delivers more detailed information than ever before. All Phenom-World scanning electron microscopes are intuitive to use, compact, fast to create results and built to high quality standards. The most extended solution in the range is the next generation Phenom ProX. The advanced system identifies different elements in a specimen by using the integrated Element Identification software with a specially designed EDS detector. With new techniques and software-developments, the magnification range has been extended from max. 45,000x to 100,000x magnification. Combined with a resolution of 17nm, the next generation Phenom ProX is a valuable instrument for a wide variety of applications....
As of June, Leica Microsystems has launched two cameras that are ideal instruments for routine brightfield or fluorescence applications. Both cameras are equipped with sensors dedicated to the respective applications that allow live images of up to 30 frames per second and a USB 3.0 interface for fast data transfer. The Leica Application Suite (LAS) and the fluorescence counterpart LAS Advanced Fluorescence (LAS AF) software platform provide for image acquisition and support users in analysis and documentation...
Over the years, many different assays have been designed to work on many different microplate readers. As new techniques emerged, so did new microplate reader technology. The new CLARIOstar microplate reader from BMG LABTECH is the latest evolution in microplate reader instrumentation....
FLIR A3500sc / A6500sc series thermal imaging cameras incorporate a cooled 3-5 micron MW-IR detector making R&D applications that need better image quality, more sensitivity and a higher frame rate routine. Achieving a high thermal sensitivity of <25 mK - FLIR A3500sc / A6500sc series cameras are able to capture the finest image details and temperature difference information. In addition, precise camera synchronization and triggering makes these cameras ideal for high-speed, high sensitivity applications...
The all new Nikon SMZ25 and SMZ18 stereomicroscopes have evolved to meet the increasing needs for imaging systems that range from single cells to whole organisms. Featuring a large zoom ratio of 25:1 for the SMZ25, superior resolution and exceptional fluorescence transmission capability, the ergonomic, easy-to-use, fully motorised SMZ25 and manual SMZ18 are ideal for all bioscience applications....
The licensed 3M patents are directed to a technique for performing mass spectrometry analysis on proteins in tissue that has been preserved in paraffin. The technology enables researchers to more easily study formalin-fixed, paraffin-embedded (FFPE) tissue for life-science research and drug development. MALDI imaging has been increasingly used to analyze clinically relevant tissues such as tumor biopsies. The molecular phenotypes observed by MALDI imaging have been shown to correlate with parameters such as disease status or patient outcome, and have been successfully applied to the classification of tissue samples.
The Nano-mechanics group develops and uses novel techniques to understand molecular processes and has recently developed new instrumentation in the fields of single molecule force spectroscopy and correlation spectroscopy. There are three main areas of research: protein folding using AFM, measuring the mechanical properties of supported lipid bilayers and following the mechanical response of nano-confined fluids. This last area is performed on home-built instruments....
Liquid-crystalline polymers (LCPs) are materials with exceptionally useful mechanical properties compared with ordinary industrial polymers. LCPs are not frequently used in industry due to their prohibitive production costs, but blending an LCP with a relatively common polymer is one way to utilize them at a reduced cost. Only blends that fibrillate in situ during processing, and when the fibrils maintain a solid state, do they demonstrate these superior properties...
Scientists in the Laboratory of Microbiology at Wageningen UR are using a G:BOX Chemi system to accurately image both chemiluminescent and fluorescently labelled Western blots of multi-functional protein complexes belonging to the CRISPR/Cas proteins. These proteins degrade foreign DNA, thus protecting bacteria from infection and by studying them, the scientists hope to unravel how bacterial immune systems function. Determining pathways of bacterial immunity could lead to a number of applications, such as being able to immunise industrially important bacteria used in food production and large-scale fermentations against phage infection....
At the 2013 Control international trade fair for quality assurance, ZEISS presented its new Hardware Auto Focus and cleanroom kit for the proven Axio Imager Vario microscope system. An integratable autofocus system ensures fast and precise focusing. The Hardware Auto Focus is ideal for surface inspections on reflective, low-contrast samples. In transmitted and reflected light (brightfield, darkfield, polarization contrast and oblique illumination), the focus system ensures high precision down to 0.3 of the depth of field of the objective lens....
The TM3030 features improved electron optics to give better resolution and higher magnification capabilities together with built-in image processing to further enhance image quality. The improved electron-optical system of the TM3030 provides significantly better resolution, which is especially useful for the 5 kV mode of operation. Imaging at 5 kV reveals more surface detail and can be used for both topographic and elemental composition imaging. The new electron optics produce sharper images at higher magnifications across its three imaging and analysis modes....
This unique patent pending design provides rich phenotypic cellular information with well-based quantitative data. Equipped with BioTek’s patented Hybrid Technology™ for microplate detection, Cytation3 includes both high sensitivity filter-based detection and a flexible monochromator based system for unmatched versatility and performance. The upgradable fluorescence cellular imaging module provides researchers rich cellular visualization analysis without the complexity and expense of standard automated microscopes, making cell imaging more accessible to a larger number of research laboratories at an affordable price...
In a recently published paper, a team from Saarland University's Biophysics and Cryotechnology department in Germany has demonstrated a powerful, Raman-scattering technique for monitoring and investigating cryopreserved samples. In particular, they confirmed unambiguously the detection of ice crystals in vitreous samples in situ at temperatures below -120°C....
The Department of Biology at New York University has been equipped with the 100th Leica TCS SP8 X, a state-of-the-art confocal laser scanning microscope with a white light laser. The system offers complete spectral freedom for fluorescence experiments. For live cell imaging, the combination of high sensitivity and low laser power provides better cell viability. The new instrument is installed in the Center for Developmental Genetics and has been used to further Assistant Professor Dr. Lionel Christiaen’s goal of understanding how tissue-specific gene regulatory networks control and coordinate cell behavior during morphogenesis since February 2013....
Focusing on ease of use for routine applications, the latest cellSens software release, version 1.8, offers flexible and user-centric imaging, processing, analysing and reporting. New and enhanced functions include a fully customisable user interface, precise frame-by-frame sample navigation and easy one-button switching between wells. For a wide range of life science applications, cellSens provides easy control of the workflow. The software binds together Olympus frames, cameras and high-quality optics to form complete, highly precise and user-friendly microscopy systems....