In pharmaceutical technology and biotechnology, valuable medical and biological samples and materials often have to be preserved at extremely low temperatures for anything from several weeks to a few years.
The cooling system used in an application of this nature must be absolutely safe and reliable. Something going wrong may not only lead to the loss of valuable samples, expensive reagents, or entire research results but also significant amounts of time and money. Reputations can also suffer. The UF V series ultralow temperature freezer by BINDER, the world's largest specialist manufacturer of simulation chambers for scientific and industrial laboratories, has been designed for the safe long-term...
Syngene, a world-leading manufacturer of image analysis solutions is delighted to announce that the G:BOX Chemi XRQ high resolution, multi-application image analysis system is being successfully used at the Lithuanian University of Health Sciences Academy of Medicine to study molecular mechanisms of cardiac stem cell function which could help in developing stem cell therapies for heart repair.
Researchers in the Laboratory of Cell Culture at the Lithuanian University of Health Sciences Academy of Medicine are utilising the easy-to-use G:BOX Chemi XRQ system to image and analyse proteins on chemiluminescent Western blots and DNA gels stained with SYBR® Safe dyes. The image analysis data is being used to investigate the effects that genetic modification have on how stem cells differentiate into cardiac myocytes and integrate into cardiac...
Gel Company/Aplegen announce its most sensitive HRP substrate for Western blotting yet.
This chemiluminescent product joins the Company’s extensive range of over 800 reagents and consumables for the life scientist. Chemi FP has attomole sensitivity and a very long lasting signal output. The light emission is stable for 10 times longer than with typical ECL substrates. This now enables the user to detect bands not usually visualised with other substrates that are commonly used. Importantly, the high signal-to-noise level and large dynamic...
SP Scientific has introduced a new range of Hotpack Undercounter and Doublestack Glassware Washers that are engineered for productive, reliable and energy efficient operation.
Technological developments allow the new washers to deliver enhanced drying performance from an upgraded dual fan system incorporated in the washer chambers. Wash cycles with temperatures up to 70°C (158°F) enable fast, efficient cleaning of different types of glassware in wide ranging load scenarios. New soft touch features with multiple cycle selections and microprocessor control systems ensure that each load is processed with minimum energy consumption. A delayed start...
AstraZeneca today announced updated data on AZD9291 in first-line patients with epidermal growth factor receptor mutation (EGFRm) positive advanced non-small cell lung cancer (NSCLC) and previously-treated patients with EGFRm T790M mutation-positive NSCLC.
The data being presented today at the World Conference on Lung Cancer (WCLC) 2015 were from the AURA Phase I trial first-line cohort and two AURA Phase II studies. Data demonstrated that in 60 patients who received AZD9291 once daily in the first-line setting, 72% (95% confidence interval (CI) 58% to 82%) were progression free (PFS) at 12 months. Confirmed overall response rate (ORR) was 75% (95% CI 62% to 85%). The longest duration of...
Cleaver Scientific announces the introduction of a horizontal polyacrylamide gel electrophoresis (hPAGE) system developed in collaboration with the Kirkhouse Trust, an organisation supporting research and education in the biological sciences.
Synbiosis, a long-established, expert manufacturer of automated microbiological systems, today introduced its mASTer (measuring Antibiotic Susceptibility Testing easily and rapidly) software.
This revolutionary software saves microbiologists hours of work by reproducibly measuring zones around antibiotic discs on AST (Antibiotic Sensitivity Testing) plates and then automatically producing a bacteria’s antibiotic SIR (Susceptible, Intermediate, Resistant) category. The versatile mASTer software can be used to analyse AST plate images generated by a Synbiosis ProtoCOL 3 automated zone measurement system or from a Syngene G:BOX...
Specialised Imaging has updated and expanded its resources web page for scientists and engineers interested in or involved with ultra high-speed imaging.
The company's comprehensive range of high resolution framing cameras, trajectory trackers, still cameras, image intensifiers and accessories open the door to exciting discoveries, ground breaking research and new measurement solutions in a wide range of applications areas. Visitors to the website are given open access to an informative bibliography of research articles, application notes, video clips and still images...
Investment will accelerate development of DESKGEN genome editing software platform
Desktop Genetics Ltd (“DTG” or “the Company”), a UK bioinformatics company aiming to revolutionize the way genetic researchers work, announced today that it has secured an investment of £1.37M GBP ($2.15M USD) from a syndicate of VCs and angel investors, including IQ Capital Partners, London Business Angels, the London Co-Investment Fund, Dr Jonathan Milner (Deputy Chairman and Founder of Abcam plc), Dr Martin Murphy (CEO of Syncona Partners LLP) and Dr Darrin M Disley (CEO of Horizon Discovery Group plc). This latest round of investment will enable Desktop Genetics to
Olympus has unveiled its new Cell Counter to enhance workflow productivity in cell culturing.
The Cell Counter model R1 is a cost-effective solution that saves time and simplifies the cell counting process. Engineered with leading-edge technology in a portable design, the new Olympus Cell Counter model R1 offers user-friendly and cost-effective cell counting for routine cell culturing. Accurate cell counts are important for a variety of research applications, including regenerative and drug medicine. Rather than relying on a human operator to manually count...
Leading molecular diagnostics firm Multiplicom N.V. today unveiled its MASTR Facility to enable the implementation of massively parallel sequencing (MPS also referred to as NGS) capabilities in clinical genetics and pathology laboratories.
The MASTR Facility will allow labs to unlock the power of personalized medicine for improved patient outcomes in a more expedited and cost effective manner. With the MASTR Facility and the current and near-term portfolio of innovative test kits, Multiplicom feels well-positioned to drive industry-leading growth. Molecular diagnostics are revolutionizing healthcare. Patients and physicians demand for genetic information is exponentially growing as the...
FLIR Systems announces that the latest version of its Research IR software - ResearchIR Max version 4.2 gives users direct access to their MATLAB scripts within the software program for the first time.
This new capability allows users to access their customized MatLab® scripts directly in ResearchIR for specially-tailored thermal image analysis and processing tasks. Many useful MatLab functions can now be directly accessed from within ResearchIR. Combining FLIR thermal and other cameras with MATLAB provides you with a flexible environment to explore algorithms for multi-sensor systems. To demonstrate the powerful utility of this new capability...
The UniFlow CE is a full duty fume hood in a compact size, which offers 50% energy savings over conventional hoods.
The CE’s low flow constant volume by-pass design maintains consistent face velocity. CE fume hoods are offered in 30”, 36”, 48”, and 72” widths and can be equipped with a wide selection of accessories to meet your specific process needs. CE’s are constructed totally of composite resin for superior chemical resistance, NO RUST, and can be supplied with or without an exhaust blower in standard or explosion proof models. HEMCO is an ISO 9001-2008 Certified Company...
BRD4 inhibitors are among the most promising new agents in cancer therapy that are currently evaluated in clinical trials.
In a study published in NATURE today, a team of researchers at the Research Institute of Molecular Pathology (IMP) and Boehringer Ingelheim in Vienna reveals how leukemia cells can evade the deadly effects of BRD4 inhibition. Understanding this adaptation process could aid the development of sequential therapies to outsmart resistant leukemias. Over the past years, scientists have drawn an almost complete map of mutations in cancer. However, translating complex genetic knowledge into effective...
Eikonix, the Cambridge based imaging experts have recently introduced the MF50 Inverted Fluorescence Microscope to the UK market. This latest addition to the range of fluorescence microscopes and specialist blue/green LED lighting units gives customers an even greater choice when looking to purchase a high quality microscope unit at an affordable price.
The proportion of cancers diagnosed as a result of emergency presentation at hospital has decreased.
At the same time, the proportion of cancers diagnosed through urgent GP referral with a suspicion of cancer (known as the two week wait) has increased. Presented at the second day of the PHE Conference 2015, these results are taken from the updated Routes to Diagnosis data, covering patients diagnosed with cancer from 2006 to 2013, with 2011-2013 being published for the first time. These new preliminary figures show the proportion of patients diagnosed...
Asynt reports on how chromatography specialists - Reach Separations Ltd. are benefiting from the installation of an onsite nitrogen generator at their laboratories in Nottingham, UK.
Reach Separations specialises in chiral chromatography for the analysis and purification of small molecules. Using state-of-the-art HPLC and SFC instrumentation, Reach Separations offer screening, method development and purification for chiral and achiral molecules across the pharmaceutical, agrochemical and fine chemical sectors. To further enhance the speed and efficiency of their contract research service, Reach Separations recently invested in an Asynt nitrogen generator to replace their use of...
Maven Capital Partners (“Maven”) and Albion Ventures LLP (“Albion”), two of the largest independent venture capital investors in the UK, today jointly announce the successful sale of their investment in Lab M Holdings, a developer, manufacturer and supplier of microbiological culture media and diagnostic systems, to Neogen Corporation.
Lancashire-based Lab M is a leading provider of microbial testing and diagnostic products servicing the global food, water, industrial and clinical testing markets. Employing some 35 staff at its accredited facility in Heywood, Greater Manchester, the company’s widerange of dehydrated culture media is routinely used in microbiology laboratories around the world for food industry testing. The original Lab M investment was made by Quester VCT Plc and...
"Analytical Challenges And Solutions For Difficult Pharmaceutical Molecules"
NOVEMBER 10TH & 11TH 2015 AT GSK WARE HERTS
The Chromatographic Society is an internationally connected organisation and UK registered scientific charity devoted to the promotion and dissemination of knowledge on all aspects of chromatography and related separation techniques.
From the basic unit to the corrosion resistant model, the laboratory syringes are precision instruments intended for safe and reliable liquid distribution.
The selection of pistol grip and two ring instruments comes in a wide volume range and features following highlights Optimal hand balance and ergonomics. Both pistol grip and two-ring handles fit any hand in a comfortable way. Activation performed with limited effort for efficient work even during long dispensing series. Fast and reliable volume setting. Set within seconds, the volume will not vary while activating the syringe, thanks to the safety-locking nut on the micrometric screw. The range offer dosing possibilities from 0.025 mL to 20 mL.....
JULABO is introducing a new generation of refrigerated and heating circulators.
The new circulators of the CORIO™ series will replace the successful Economy series models and will give users improved performance specifications, expanded functionality, and even greater value for the money. JULABO circulators are used worldwide for applications in research, science, laboratories, pilot plants, and the process industry....
Introduction of a 60 litre benchtop steriliser by specialist laboratory autoclave manufacturer Priorclave gives laboratories with restricted floor space the opportunity to buy into a slightly larger benchtop autoclave offering a level of performance settings and operating flexibility usually reserved for larger floor-standing autoclaves.
The featured packed H60 autoclaves, the latest benchtop models from Priorclave and available in both standard and vacuum models, are ideal for a wide range of sterilising applications such as media preparation, laboratory waste, liquids and diluents, glassware, instruments and apparatus.
The cooling system used in an application of this nature must be absolutely safe and reliable. Something going wrong may not only lead to the loss of valuable samples, expensive reagents, or entire research results but also significant amounts of time and money. Reputations can also suffer. The UF V series ultralow temperature freezer by BINDER, the world's largest specialist manufacturer of simulation chambers for scientific and industrial laboratories, has been designed for the safe long-term...
Researchers in the Laboratory of Cell Culture at the Lithuanian University of Health Sciences Academy of Medicine are utilising the easy-to-use G:BOX Chemi XRQ system to image and analyse proteins on chemiluminescent Western blots and DNA gels stained with SYBR® Safe dyes. The image analysis data is being used to investigate the effects that genetic modification have on how stem cells differentiate into cardiac myocytes and integrate into cardiac...
This chemiluminescent product joins the Company’s extensive range of over 800 reagents and consumables for the life scientist. Chemi FP has attomole sensitivity and a very long lasting signal output. The light emission is stable for 10 times longer than with typical ECL substrates. This now enables the user to detect bands not usually visualised with other substrates that are commonly used. Importantly, the high signal-to-noise level and large dynamic...
Technological developments allow the new washers to deliver enhanced drying performance from an upgraded dual fan system incorporated in the washer chambers. Wash cycles with temperatures up to 70°C (158°F) enable fast, efficient cleaning of different types of glassware in wide ranging load scenarios. New soft touch features with multiple cycle selections and microprocessor control systems ensure that each load is processed with minimum energy consumption. A delayed start...
The data being presented today at the World Conference on Lung Cancer (WCLC) 2015 were from the AURA Phase I trial first-line cohort and two AURA Phase II studies. Data demonstrated that in 60 patients who received AZD9291 once daily in the first-line setting, 72% (95% confidence interval (CI) 58% to 82%) were progression free (PFS) at 12 months. Confirmed overall response rate (ORR) was 75% (95% CI 62% to 85%). The longest duration of...
Whilst vertical systems are commonly used for polyacrylamide gel electrophoresis, this newly developed unit’s horizontal format allows for a large number of samples to be run simultaneously and combines this with the greater resolution of polyacrylamide compared with agarose. The main advantage of the system is that it is very simple to pour and cast the polyacrylamide gels which takes away some of the complexity normally associated with vertical gel casting....
This revolutionary software saves microbiologists hours of work by reproducibly measuring zones around antibiotic discs on AST (Antibiotic Sensitivity Testing) plates and then automatically producing a bacteria’s antibiotic SIR (Susceptible, Intermediate, Resistant) category. The versatile mASTer software can be used to analyse AST plate images generated by a Synbiosis ProtoCOL 3 automated zone measurement system or from a Syngene G:BOX...
The company's comprehensive range of high resolution framing cameras, trajectory trackers, still cameras, image intensifiers and accessories open the door to exciting discoveries, ground breaking research and new measurement solutions in a wide range of applications areas. Visitors to the website are given open access to an informative bibliography of research articles, application notes, video clips and still images...
Desktop Genetics Ltd (“DTG” or “the Company”), a UK bioinformatics company aiming to revolutionize the way genetic researchers work, announced today that it has secured an investment of £1.37M GBP ($2.15M USD) from a syndicate of VCs and angel investors, including IQ Capital Partners, London Business Angels, the London Co-Investment Fund, Dr Jonathan Milner (Deputy Chairman and Founder of Abcam plc), Dr Martin Murphy (CEO of Syncona Partners LLP) and Dr Darrin M Disley (CEO of Horizon Discovery Group plc). This latest round of investment will enable Desktop Genetics to
The Cell Counter model R1 is a cost-effective solution that saves time and simplifies the cell counting process. Engineered with leading-edge technology in a portable design, the new Olympus Cell Counter model R1 offers user-friendly and cost-effective cell counting for routine cell culturing. Accurate cell counts are important for a variety of research applications, including regenerative and drug medicine. Rather than relying on a human operator to manually count...
The MASTR Facility will allow labs to unlock the power of personalized medicine for improved patient outcomes in a more expedited and cost effective manner. With the MASTR Facility and the current and near-term portfolio of innovative test kits, Multiplicom feels well-positioned to drive industry-leading growth. Molecular diagnostics are revolutionizing healthcare. Patients and physicians demand for genetic information is exponentially growing as the...
This new capability allows users to access their customized MatLab® scripts directly in ResearchIR for specially-tailored thermal image analysis and processing tasks. Many useful MatLab functions can now be directly accessed from within ResearchIR. Combining FLIR thermal and other cameras with MATLAB provides you with a flexible environment to explore algorithms for multi-sensor systems. To demonstrate the powerful utility of this new capability...
The CE’s low flow constant volume by-pass design maintains consistent face velocity. CE fume hoods are offered in 30”, 36”, 48”, and 72” widths and can be equipped with a wide selection of accessories to meet your specific process needs. CE’s are constructed totally of composite resin for superior chemical resistance, NO RUST, and can be supplied with or without an exhaust blower in standard or explosion proof models. HEMCO is an ISO 9001-2008 Certified Company...
In a study published in NATURE today, a team of researchers at the Research Institute of Molecular Pathology (IMP) and Boehringer Ingelheim in Vienna reveals how leukemia cells can evade the deadly effects of BRD4 inhibition. Understanding this adaptation process could aid the development of sequential therapies to outsmart resistant leukemias. Over the past years, scientists have drawn an almost complete map of mutations in cancer. However, translating complex genetic knowledge into effective...
Eikonix, the Cambridge based imaging experts have recently introduced the MF50 Inverted Fluorescence Microscope to the UK market. This latest addition to the range of fluorescence microscopes and specialist blue/green LED lighting units gives customers an even greater choice when looking to purchase a high quality microscope unit at an affordable price.
At the same time, the proportion of cancers diagnosed through urgent GP referral with a suspicion of cancer (known as the two week wait) has increased. Presented at the second day of the PHE Conference 2015, these results are taken from the updated Routes to Diagnosis data, covering patients diagnosed with cancer from 2006 to 2013, with 2011-2013 being published for the first time. These new preliminary figures show the proportion of patients diagnosed...
Reach Separations specialises in chiral chromatography for the analysis and purification of small molecules. Using state-of-the-art HPLC and SFC instrumentation, Reach Separations offer screening, method development and purification for chiral and achiral molecules across the pharmaceutical, agrochemical and fine chemical sectors. To further enhance the speed and efficiency of their contract research service, Reach Separations recently invested in an Asynt nitrogen generator to replace their use of...
Lancashire-based Lab M is a leading provider of microbial testing and diagnostic products servicing the global food, water, industrial and clinical testing markets. Employing some 35 staff at its accredited facility in Heywood, Greater Manchester, the company’s widerange of dehydrated culture media is routinely used in microbiology laboratories around the world for food industry testing. The original Lab M investment was made by Quester VCT Plc and...
The selection of pistol grip and two ring instruments comes in a wide volume range and features following highlights Optimal hand balance and ergonomics. Both pistol grip and two-ring handles fit any hand in a comfortable way. Activation performed with limited effort for efficient work even during long dispensing series. Fast and reliable volume setting. Set within seconds, the volume will not vary while activating the syringe, thanks to the safety-locking nut on the micrometric screw. The range offer dosing possibilities from 0.025 mL to 20 mL.....
The new circulators of the CORIO™ series will replace the successful Economy series models and will give users improved performance specifications, expanded functionality, and even greater value for the money. JULABO circulators are used worldwide for applications in research, science, laboratories, pilot plants, and the process industry....
The featured packed H60 autoclaves, the latest benchtop models from Priorclave and available in both standard and vacuum models, are ideal for a wide range of sterilising applications such as media preparation, laboratory waste, liquids and diluents, glassware, instruments and apparatus.