World First Clinical Trial Of New Cancer Drug By Australia’s Asbestos Diseases Research Institute
Today, Australia’s Asbestos Diseases Research Institute (ADRI) announced a world-first clinical trial into a newly developed drug therapy for the treatment of mesothelioma, a cancer which is almost uniquely caused by exposure to asbestos fibers. In most patients with mesothelioma the disease has significantly advanced before symptoms appear, making an early diagnosis and effective treatment very difficult. There is no cure. The average survival time after diagnosis is 6-18 months...
The PapilloCheck HPV test from Greiner Bio-One GmbH, technology partner for the diagnostic and pharmaceutical industries, has now received approval from the Dutch Society for Pathology following successful validation based on international guidelines for HPV-DNA tests.
Cervical cancer is one of the most frequent cancers among women. It is caused by a persistent infection involving certain types of human papillomaviruses (HPV). If this infection is detected at an early stage and the patient is given appropriate medical treatment, the development of cervical cancer can be prevented in virtually all cases. HPV tests, which detect the carcinogenic virus, therefore play a major role in cervical cancer screening...
German company LCTech GmbH, a supplier of products and methods for sample preparation and analysis, has been using Tecan Cavro® components for many years and has incorporated a Cavro Omni Robot and Cavro XLP Pump into its latest FREESTYLE sample preparation workstation.
Dr Uwe Aulwurm, a Managing Director of LCTech, explained: “To meet the varied workflow demands of our customers, we wanted a modular solution that combined a general purpose liquid handling system with a range of different processing devices, including options for solid phase extraction, gel permeation chromatography and evaporation. The Cavro Omni Robot was perfectly suited to our needs, providing a very robust instrument which could be easily modified to access individual processing modules...
Program will emphasize a combination of training in classical clinical chemistry and specialty areas
Waters Corporation (NYSE:WAT) announced today sponsorship of a new, two-year, postdoctoral Clinical Chemistry Fellowship at the University of California, San Diego School of Medicine. Fellows will be trained in classical clinical chemistry, laboratory administration and research practices to prepare them for directorship positions at medical schools or hospital-based clinical chemistry laboratories. “Our mission is to develop the next generation of leaders in clinical chemistry,” said Robert Fitzgerald, Ph.D., DABCC, UC San Diego School of Medicine professor of pathology and faculty coordinator of the new Clinical Chemistry Fellowship program...
Thermo Fisher Scientific has developed a high-performance liquid chromatography (HPLC) method for a fast and sensitive determination of paraquat and diquat in tap and environmental water samples.
This approach uses on-line solid phase extraction (SPE) and achieves method detection limits that meet the requirements of both U.S. Environmental Protection Agency Method 549.2 and European Union 98/83/EC. Application Note (AN) 1051: Sensitive and Rapid Determination of Paraquat and Diquat in Tap and Environmental Water demonstrates use of a mixed-mode column to provide sufficient retention, excellent resolution, and good peak shape for these herbicides...
Within weeks of the Supreme Court’s historic decision declaring that human genes cannot be patented, two scientists have started a company that will democratize the human genome and give people direct access to their own genetic information - which can have an immediate impact on their health and wellbeing.
The court’s decision in Association for Molecular Pathology v. Myriad Genetics, on June 13, opened an era of genomic liberty, allowing people to look at the DNA for all of their genes – which had been hidden behind patent walls for companies that had a monopoly on such testing....
Crown Bioscience, Inc., a leading global drug discovery and development service company, today announces that it has acquired the shares of Preclinical Oncology Services Limited (PRECOS), a leading pre-clinical research and development service provider with a specific focus on oncology.
As a result of the acquisition Crown Bioscience becomes the world’s only contract research organization that offers such a comprehensive range of services. It will become the largest supplier of oncology services with a global footprint, spanning three major continents in North America, Europe and Asia Pacific...
Long-term storage of clinical samples will be critical to the growth of biobanking
The global proliferation of disease-based regional and national biobanks for clinical research has triggered a massive interest in long-term sample storage conditions. Simultaneously, it has spawned a requirement for good storage practices and standard operating procedures (SOPs)...
Malvern Instruments has kicked off a brand new series of Masterclass webinars available both as live events and subsequently as recorded presentations.
Based on the company’s established Masterclass concept, the ‘Masterclass on Suspension Properties’ series guides participants on how to use rheology in combination with other analytical techniques in order to formulate suspensions to meet specific performance targets. The information is delivered in a very straightforward style, making the subject easily accessible and comprehensible to the broadest of audiences...
Multi-mode microplate readers are an indispensable laboratory instrument that enable many applications to be performed on multiple samples.
Life science applications involving cells are increasingly desired due to higher biological relevance associated with functional readouts. Microplate readers can provide quantification of a specific target, such as a protein or its post-translational modification, or phenotypes such as cell death through apoptosis or necrosis. Quantification is provided relative to assay controls and/or standards using dispersive optical detection and light collection with photomultiplier tubes (PMT)...
Thermo Fisher Scientific is pleased to announce a new technical note discussing rapid separation of inorganic cations in municipal wastewater using our high pressure capillary Ion Chromatography system, the Thermo Scientific Dionex 5000+ ICS HPIC system.
Technical Note 121: Fast Determinations of Inorganic Cations in Municipal Wastewater Using High-Pressure Capillary IC demonstrates how the separation of inorganic cations are important to municipal drinking water and wastewater treatment plants for compliance monitoring. Cationic determinations are necessary as part of the water monitoring program’s secondary water specification of acceptable taste....
Xmark Media the organisers of Photonex 2013, the UK's showcase photonics conference & exhibition announce the programme and speakers for the meeting on Nano and Bio-Imaging. This FREE-to-attend conference will be held on Wednesday 16th October as part of a diverse two-day event at the visitor-friendly Ricoh Arena in Coventry.
Significant advances in the development of optical techniques have led to an inter-disciplinary use of photonics in the study of various problems in the life sciences, in biological and chemical sciences, in medicine, clinical sciences, neurophysiology etc. Researchers are continually looking for better ways to analyse complex processes....
Link Technologies’ new Product Guide is the ‘go-to’ resource for oligo chemistry
Link Technologies Ltd, a specialist oligonucleotide reagent manufacturer, has used its 25 years of industry experience to produce the 2013/14 Product Guide, providing scientists with a wealth of application-orientated content for oligonucleotide chemistry. For easy navigation, the guide is broken into key topics and processes, including Oligonucleotide Labelling Strategies, and each section is supported by application notes and protocols, for easy product-to-practice transition...
JPK Instruments, a world-leading manufacturer of nanoanalytic instrumentation for research in life sciences and soft matter, reports on how researchers from the Université de Paris-Sud and CNRS Montpellier have used the new QI mode of AFM imaging to quantitatively characterize living bacteria without any immobilization.
Dr Christian Marlière of the Institute of Molecular Sciences (ISMO) located at the Université Paris Sud, CNRS, Orsay leads a research team to study the dynamics and properties (mechanical, electrical and electro-chemical) of living bacteria in purely controlled physiological conditions at nanometer scale: motility or adhesion processes of bacteria on solid substrates, biofilms formation, the influence of light on moving properties of cyanobacteria, effects of antibiotics on bacterial membranes and biofilm etc....
To Help Train Professionals how to Optimise Their Decontamination Processes
Scientific Digital Imaging’s [AIM-SDI] Synoptics Health Division, a manufacturer of innovative digital imaging systems for healthcare applications, today announced that major international healthcare training centre, Eastwood Park, UK will be using ProReveal, a test to detect proteins on surgical instruments, to complement training of sterile services professionals on how to assess the validity of decontamination processes....
METTLER TOLEDO is pleased to present a new white paper to help those working in the Chemical, Food, Consumer Product, and Mineral industries meet the challenge of understanding, optimizing and controlling particle and droplet systems in a variety of applications including suspensions, emulsions and crystallizations.
“Best Practice for Inline Particle Size Characterization” reviews a series of real-life examples where prominent food, chemical and consumer product companies have used inline characterization methods to measure real time particle size dynamics at full-process concentration to ensure repeatable process endpoints, improve yield, and optimize product quality. Inconsistencies in solid or liquid dispersion, agglomeration or precipitation can create variability in product stability and manufacturing throughput...
Porvair Sciences has announced the first North American edition* of its internationally trusted ‘Catalog of Microplates and Microplate Equipment’.
Many scientists around the world have come to rely upon the Porvair Sciences catalog as a trusted source of information that enables them to choose the optimum microplate, microplate evaporator or sealer for their application. This new2013 edition brings together information on Porvair Sciences comprehensive microplate and microplate equipment product range that is available and supported by knowledgable local agents** through the USA and Canada. Reflecting Porvair's continuing commitment to continuous technological innovation, the North American catalog introduces a suite of exciting new products..
New Oxford Biotech Launches Cloning Platform that Promises to Transform Synthetic Biology and Genetic Engineering
Oxfordshire’s newest biotechnology company, Oxford Genetics Ltd, has developed an innovative range of synthetic DNA products that are set to revolutionise the genetic research sector. The new technology, called SnapFastTM, provides a fully interchangeable module based genetic engineering platform that offers research scientists unrivalled efficiency and flexibility...
Introductory 3 for 2 exome sequencing and analyses offer
Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, has extended its high-quality whole exome sequencing services with a targeted Familial Sequencing and Analysis Service. Ideal for investigators of inherited disease, the new service delivers multi-genome analysis of related samples for the detection of causative, de novo and disease susceptibility mutations. With a fully optimised workflow, OGT offers the entire targeted next generation sequencing pipeline, from project design through to end-point mutation discovery and extensive variant annotation...
The Institute of Nanotechnology (IoN) will be the official charity partner of the largest international nanotechnology conference to take place in the UK.
Nano London 2014 will take place from 17th-19th June 2014 at Olympia in London, and brings together industry leaders, academics, manufacturers, suppliers and investors in the fast growing field of nanotechnology. The IoN is a registered charity which supports education and training within the nanotechnology community and provides industry and governments with intelligence on nanotechnology and its applications. The Institute has a global network of members and is highly active in European research programmes such as FP7...
New SIRTainty™ Class III HDAC Assay From Merck Millipore Used in Recent Study Demonstrating Novel Mechanism for Activation of SIRT1
Assay format allows for simple, sensitive detection of sirtuin activity on any desired substrate. Avoids shortcomings of other sirtuin assays that require the use of specific, artificially fluorophore-tagged substrates. Study published in Science identified novel mechanism for activation of SIRT1 using assay. Merck Millipore, the Life Science division of Merck, introduced the SIRTainty™ Class III HDAC assay which allows for simple, sensitive detection of sirtuin activity on any desired substrate...
Read MoreAndor iXon 897 EMCCD camera discovers two undetected stars in well-mapped globular clusterAug 7, 2013
iXon EMCCD camera's spatial resolution and high readout speed demonstrate possibility of finding more stars and planetary systems in our galaxy
With the accelerating interest in seeking out Earth 2.0 exoplanets, the need for accurate star maps on which to base our searches only increases. However, an international team of scientists has found two previously undetected stars in a recently mapped globular cluster using the ultra-sensitive Andor iXon 897 Electron Multiplying CCD camera on the Danish 1.54m telescope at La Silla, Chile. This discovery raises the possibility that we can pinpoint more potential target planets that would be hospitable to life...
Cervical cancer is one of the most frequent cancers among women. It is caused by a persistent infection involving certain types of human papillomaviruses (HPV). If this infection is detected at an early stage and the patient is given appropriate medical treatment, the development of cervical cancer can be prevented in virtually all cases. HPV tests, which detect the carcinogenic virus, therefore play a major role in cervical cancer screening...
Waters Corporation (NYSE:WAT) announced today sponsorship of a new, two-year, postdoctoral Clinical Chemistry Fellowship at the University of California, San Diego School of Medicine. Fellows will be trained in classical clinical chemistry, laboratory administration and research practices to prepare them for directorship positions at medical schools or hospital-based clinical chemistry laboratories. “Our mission is to develop the next generation of leaders in clinical chemistry,” said Robert Fitzgerald, Ph.D., DABCC, UC San Diego School of Medicine professor of pathology and faculty coordinator of the new Clinical Chemistry Fellowship program...
The court’s decision in Association for Molecular Pathology v. Myriad Genetics, on June 13, opened an era of genomic liberty, allowing people to look at the DNA for all of their genes – which had been hidden behind patent walls for companies that had a monopoly on such testing....
As a result of the acquisition Crown Bioscience becomes the world’s only contract research organization that offers such a comprehensive range of services. It will become the largest supplier of oncology services with a global footprint, spanning three major continents in North America, Europe and Asia Pacific...
Based on the company’s established Masterclass concept, the ‘Masterclass on Suspension Properties’ series guides participants on how to use rheology in combination with other analytical techniques in order to formulate suspensions to meet specific performance targets. The information is delivered in a very straightforward style, making the subject easily accessible and comprehensible to the broadest of audiences...
Technical Note 121: Fast Determinations of Inorganic Cations in Municipal Wastewater Using High-Pressure Capillary IC demonstrates how the separation of inorganic cations are important to municipal drinking water and wastewater treatment plants for compliance monitoring. Cationic determinations are necessary as part of the water monitoring program’s secondary water specification of acceptable taste....
Significant advances in the development of optical techniques have led to an inter-disciplinary use of photonics in the study of various problems in the life sciences, in biological and chemical sciences, in medicine, clinical sciences, neurophysiology etc. Researchers are continually looking for better ways to analyse complex processes....
Link Technologies Ltd, a specialist oligonucleotide reagent manufacturer, has used its 25 years of industry experience to produce the 2013/14 Product Guide, providing scientists with a wealth of application-orientated content for oligonucleotide chemistry. For easy navigation, the guide is broken into key topics and processes, including Oligonucleotide Labelling Strategies, and each section is supported by application notes and protocols, for easy product-to-practice transition...
Dr Christian Marlière of the Institute of Molecular Sciences (ISMO) located at the Université Paris Sud, CNRS, Orsay leads a research team to study the dynamics and properties (mechanical, electrical and electro-chemical) of living bacteria in purely controlled physiological conditions at nanometer scale: motility or adhesion processes of bacteria on solid substrates, biofilms formation, the influence of light on moving properties of cyanobacteria, effects of antibiotics on bacterial membranes and biofilm etc....
“Best Practice for Inline Particle Size Characterization” reviews a series of real-life examples where prominent food, chemical and consumer product companies have used inline characterization methods to measure real time particle size dynamics at full-process concentration to ensure repeatable process endpoints, improve yield, and optimize product quality. Inconsistencies in solid or liquid dispersion, agglomeration or precipitation can create variability in product stability and manufacturing throughput...
Assay format allows for simple, sensitive detection of sirtuin activity on any desired substrate. Avoids shortcomings of other sirtuin assays that require the use of specific, artificially fluorophore-tagged substrates. Study published in Science identified novel mechanism for activation of SIRT1 using assay. Merck Millipore, the Life Science division of Merck, introduced the SIRTainty™ Class III HDAC assay which allows for simple, sensitive detection of sirtuin activity on any desired substrate...
With the accelerating interest in seeking out Earth 2.0 exoplanets, the need for accurate star maps on which to base our searches only increases. However, an international team of scientists has found two previously undetected stars in a recently mapped globular cluster using the ultra-sensitive Andor iXon 897 Electron Multiplying CCD camera on the Danish 1.54m telescope at La Silla, Chile. This discovery raises the possibility that we can pinpoint more potential target planets that would be hospitable to life...