Thermo Scientific NanoDrop One spectrophotometers designed to identify contaminants, providing accurate concentrations
Life scientists who work with DNA, RNA and proteins can make educated decisions about sample suitability in experiments using a standalone, microvolume spectrophotometer for accurate quantitation and purity measurements to ensure downstream application success. The Thermo Scientific NanoDrop One and NanoDrop OneC UV-Vis microvolume spectrophotometers are designed to help life science researchers gain a more complete...
Cell History File designed as ‘cell passport’ for developers and manufacturers of tissue and cell based medicinal products
The Cell Therapy Catapult, the organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the availability of the Cell History File (CHF) template document. The Cell History File template has been developed in conjunction with the UK’s Medicines and Healthcare products Regulatory Agency (MHRA), the Human Tissue Authority (HTA) and...
BioTek Instruments recently donated $10,000 to the Pulmonary and Critical Care Division at the University of Vermont (UVM) College of Medicine, in Burlington, Vermont to support the program's research into lung health and disease.
A multi-disciplinary team of UVM engineers, physicians, researchers and senior engineering students will use the funds to develop a customized 3D bioprinter from an existing 3D printer without existing bio-capabilities. This will allow the development of novel, multi-perspective approaches for studying lung airways and lung regeneration. The 3D bioprinter modifications will be spearheaded and jointly coordinated by Patrick Lee, Ph.D., UVM...
Quotient Clinical has announced that CEO Mark Egerton has received an EY Entrepreneur of the Year® 2015 UK Award.
Chosen by a panel of independent judges, the award acknowledges outstanding entrepreneurs who demonstrate excellence and extraordinary success in areas such as innovation, financial performance and personal commitment to their businesses and communities. Dr Egerton was one of 13 business leaders recognised for their achievements, and received his award at a special dinner held at The Brewery, London on the 5th of October. Dr Egerton commented...
INTEGRA has published a new white paper that discusses how observing good pipetting practice helps to achieve better results in serial dilution assays.
Preparation of reproducible serial dilution assays, especially in 384-well plates, is a challenging task because they require many pipetting actions and are highly dependent on an operator's technique and experience. However, observing good pipetting practice helps immensely to improve reproducibility and accuracy. In this white paper the author focuses on a selection of good pipetting techniques, which if maintained offer the best chance of...
AMSBIO has launched a unique series of monoclonal and polyclonal antibodies against S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) that allows immunoassays to be used in methylation regulation research.
Methylation is involved in nearly every aspect of life. SAM is the sole methyl donor for a variety of methyl-transfer reactions in DNA, RNA, proteins, lipids, phosphilipids, hormones and neurotransmitters. Proper DNA methylation is essential for normal embryonic development. However, when the methyl-transferase gene is homozygously deleted, it is lethal. DNA improperly methylated has been found in many tumors. Alterations in...
East Midlands health and social care under the spotlight as regional awards recognise incredible innovations
The East Midlands Academic Health Science Network (EMAHSN) shines a light on health and social care as finalists from across the region, including two projects involving University of Leicester researchers, are announced in the second East Midlands Innovation in Healthcare awards. The shortlist highlights the astonishing range of innovations and ideas developed by frontline healthcare staff, local patients, charities, companies, GP surgeries...
Lonza, one of the market leaders in primary cells, has announced an increase in recent publications referencing its specialized BulletKit™ Growth and Differentiation Media.
These peer-reviewed papers highlight the versatility of the media kits, which are proving especially useful for researchers looking to transition from established cell lines to primary cell culture or when co-culturing different cell types, mostly due to their convenience, adaptability and ease-of-use. Researchers often work with established cell lines before transitioning to primary cells, as the former are usually easier to culture in the...
Horizon Discovery Group plc (LSE: HZD), the international life science company supplying research tools and services that power genomics research and the development of personalised medicines, announces today that its leveraged business unit has signed a programme in-licensing and option agreement with Servier, the independent French research-based pharmaceutical company.
The agreement is potentially worth over £50 million to Horizon in preclinical and clinical milestones, payments linked to net sales, and tiered royalties on future product sales. Horizon has in-licensed novel kinase inhibitors from Servier that exhibit great promise based on pre-clinical data for treatment of a range of cancer types but do not currently have a biomarker to define a sensitive patient population. Horizon will use its world-leading platform...
Trends and Challenges in Quality Assurance and Regulatory Compliance
The Sartorius Lab Technology Forum will focus on the latest trends and challenges in quality assurance and regulatory compliance. This is the perfect opportunity to share knowledge and novel approaches with industry leaders and peers. International experts from the pharmaceutical and biotech industry, universities and the National Regulatory & Safety Institutes will cover topics of high interest around quality control, development...
With its unrivalled sensitivity, the PlasmaQuant ® MS Elite delivers the lowest detection limits of any ICP-MS when measuring both organic and inorganic species of arsenic in food and beverages. The high toxicity of inorganic arsenic means regular monitoring of food products is important. Various seafoods for example contain high levels of the less toxic organic arsenic species. Therefore, the dangers of arsenic depend not only on the total concentration, but also its chemical forms which vary in terms of toxicity and bioavailability....
Read MoreMichigan Researchers Use Raman Spectroscopy to Study Various Childhood DiseasesOct 28, 2015
Michigan researchers use Raman spectroscopy to study various childhood diseases
Renishaw, a world leader in metrology and spectroscopy, reports on the use of its inVia confocal Raman microscope in the study of various diseases–with a major focus on childhood diseases–at the Children's Hospital of Michigan and Wayne State University. Dr Michael Klein is a surgeon with the Children's Hospital of Michigan–a part of the Detroit Medical Center (DMC)–and a researcher with the Department of Surgery at Wayne...
Photometrics Prime™ goes beyond imaging by quantitatively restoring images hidden in photon shot noise
Photometrics, a manufacturer of high performance scientific cameras for life science applications, today announces the release of its new sCMOS camera, the Photometrics Prime. Prime is the first 4.2 Megapixel scientific CMOS camera available for life science research that actively defeats the negative impact of Poisson noise in low light images.
Dekkera bruxellensis (D. bruxellensis) is a yeast native to the Belgian Senne valley located near Brussels. It is a hemiascomycetes yeast, meaning primitive and morphologically simple, with an absent or poorly developed mycelium and no formation of hyphae.
Its genome size ranges from under 20 to over 30 mega base pairs (Mb). The asexual reproductive form in the life cycle of this organism is known as Brettanomyces bruxellensis (B. bruxellensis), one of several members of the genus Brettanomyces. In the wild this microorganism lives on the skins of fruit and plays a key role in the production of Belgian Lambic style beers. Belgium’s beer and wine tradition is no newcomer to the alcoholic beverage industry. Belgium’s monastic, spontaneously fermenting lambic wheat beer family predates the pitching of yeast by brewers, whilst fermenting of beers with cherry (Kriek) and raspberry (Framboise) and spiced white brews predate the hop....
Aske Stephenson, a pioneering alcoholic beverage manufacturer, who will be using benchtop laboratory instruments from Bibby Scientific such as the Stuart® RE300 Rotary Evaporator to produce innovative pre-bottled cocktails.
Aske Stephenson specialises in developing hand-produced cocktails that are designed to introduce consumers to new and unusual flavour combinations, using a scientific approach that pushes taste boundaries. Bibby Scientific’s Stuart Rotary Evaporators are extremely reliable, safe and user-friendly instruments that are used widely in chemistry laboratories in universities and pharmaceutical companies. The Rotary Evaporators can also operate under vacuum, making them perfect for the unique distillation requirements of Aske Stephenson’s cocktail mixology....
The Autoclave Knowledge Bank Check Book is an impartial guide and insight into some of the key factors that could help you make the right decision before making that all important laboratory autoclave purchase.
When specifying or purchasing any expensive and complicated piece of equipment it is essential to be able to ask the right questions in order to get the right answers and make an informed decision - a few minutes at the Autoclave Knowledge Bank could save your company time and money.
Cresset, innovative provider of software and contract research services for small molecule discovery and design, is pleased to announce that Cancer Therapeutics CRC (CTx), a collaborative partnership of leading research institutes, universities and biotechnology companies in Australia, has licensed the virtual screening software Blaze for cancer research.
Blaze will be used to run virtual screening projects to translate Australia’s innovative research discoveries into new cancer drugs. “Cresset’s Blaze virtual screening platform was the obvious choice for us as it has a proven track record,” says Warwick Tong, Chief Executive Officer at CTx. “With access to a super computer at the Commonwealth Scientific and Industrial Research Organization (CSIRO) we now have the capability to run virtual...
Scientists have designed a novel method for improving the delivery of therapeutic molecules into diseased cells such as those found in cancer and tuberculosis
Many drug treatments do not work in patients because of their poor ability to reach their intended targets that lie inside cells. To address this, researchers from Cardiff University’s Schools of Pharmacy and Pharmaceutical Sciences, and Biosciences, sought to improve the delivery of a relatively new class of drugs called biotherapeutics. These drugs include antibodies, such as Herceptin, that target breast and stomach cancer cells. Cancer cells often...
Highly Automated, Self-Optimizing Micro-CT with Push-Button Ease of Use Requires Essentially No Training to Deliver Top-Notch 3D Image Quality and Productivity for Research and Industrial Markets
With the introduction of the new SKYSCAN™ 1275 highly automated, self-optimizing desktop X-ray microtomograph, Bruker puts class-leading imaging into the hands of materials and life scientists in both research and industrial applications, such as high-throughput 3D imaging in quality control and production process monitoring. The system takes advantage of new X-ray source technology and efficient flat-panel detectors to reduce...
Minister for Universities and Science Jo Johnson MP helped to break ground to mark the construction of a new University of Glasgow-led clinical imaging centre today (Monday 26 October).
The minister was visiting the site at the Queen Elizabeth University Hospital where the new Imaging Centre of Excellence (ICE) will be based. The ICE, supported by £16m of UK Government funding through the Medical Research Council as part of the Glasgow & Clyde Valley City Deal, will provide clinical research facilities which will be unique in the UK and create more than 200 new jobs for local people. The centre is expected to be...
OHAUS, a leading worldwide manufacturer of scales and balances, who recently announced the launch of Explorer® Semi-Micro, is now focused on gathering good weighing tips in order to simplify the weighing process and support the achievement of good results.
Weighing is one of the most basic tasks performed in the laboratory. That is why it is important we do not underestimate certain factors that can influence proper results. Incorrect usage or unsuitable conditions may cause errors, especially for semi-micro balances, that are used to weigh the lightest samples. OHAUS has been present on the market for over a 100 years and has always been concerned about the universal rules for good weighing as well as developing the perfect tools for that activity....
Read MoreTecan Offers Walkaway Batch Processing for the Spark 10M ReaderOct 27, 2015
Tecan’s innovative Spark 10M multimode reader can now be combined with the company’s Connect™ microplate stacker to offer semi-automated batch processing of up to 50 assay plates.
A newly developed software interface allows seamless operation of the Connect stacker through the reader’s SparkControl™ software, helping to streamline laboratory workflows for greater productivity. The Connect is a versatile microplate stacker designed to offer fast, smooth transfer of plates to and from the host instrument. Already popular with users of Tecan’s Infinite® series microplate readers and HydroSpeed™ plate...
Life scientists who work with DNA, RNA and proteins can make educated decisions about sample suitability in experiments using a standalone, microvolume spectrophotometer for accurate quantitation and purity measurements to ensure downstream application success. The Thermo Scientific NanoDrop One and NanoDrop OneC UV-Vis microvolume spectrophotometers are designed to help life science researchers gain a more complete...
The Cell Therapy Catapult, the organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the availability of the Cell History File (CHF) template document. The Cell History File template has been developed in conjunction with the UK’s Medicines and Healthcare products Regulatory Agency (MHRA), the Human Tissue Authority (HTA) and...
A multi-disciplinary team of UVM engineers, physicians, researchers and senior engineering students will use the funds to develop a customized 3D bioprinter from an existing 3D printer without existing bio-capabilities. This will allow the development of novel, multi-perspective approaches for studying lung airways and lung regeneration. The 3D bioprinter modifications will be spearheaded and jointly coordinated by Patrick Lee, Ph.D., UVM...
Chosen by a panel of independent judges, the award acknowledges outstanding entrepreneurs who demonstrate excellence and extraordinary success in areas such as innovation, financial performance and personal commitment to their businesses and communities. Dr Egerton was one of 13 business leaders recognised for their achievements, and received his award at a special dinner held at The Brewery, London on the 5th of October. Dr Egerton commented...
Preparation of reproducible serial dilution assays, especially in 384-well plates, is a challenging task because they require many pipetting actions and are highly dependent on an operator's technique and experience. However, observing good pipetting practice helps immensely to improve reproducibility and accuracy. In this white paper the author focuses on a selection of good pipetting techniques, which if maintained offer the best chance of...
Methylation is involved in nearly every aspect of life. SAM is the sole methyl donor for a variety of methyl-transfer reactions in DNA, RNA, proteins, lipids, phosphilipids, hormones and neurotransmitters. Proper DNA methylation is essential for normal embryonic development. However, when the methyl-transferase gene is homozygously deleted, it is lethal. DNA improperly methylated has been found in many tumors. Alterations in...
The East Midlands Academic Health Science Network (EMAHSN) shines a light on health and social care as finalists from across the region, including two projects involving University of Leicester researchers, are announced in the second East Midlands Innovation in Healthcare awards. The shortlist highlights the astonishing range of innovations and ideas developed by frontline healthcare staff, local patients, charities, companies, GP surgeries...
These peer-reviewed papers highlight the versatility of the media kits, which are proving especially useful for researchers looking to transition from established cell lines to primary cell culture or when co-culturing different cell types, mostly due to their convenience, adaptability and ease-of-use. Researchers often work with established cell lines before transitioning to primary cells, as the former are usually easier to culture in the...
The agreement is potentially worth over £50 million to Horizon in preclinical and clinical milestones, payments linked to net sales, and tiered royalties on future product sales. Horizon has in-licensed novel kinase inhibitors from Servier that exhibit great promise based on pre-clinical data for treatment of a range of cancer types but do not currently have a biomarker to define a sensitive patient population. Horizon will use its world-leading platform...
The Sartorius Lab Technology Forum will focus on the latest trends and challenges in quality assurance and regulatory compliance. This is the perfect opportunity to share knowledge and novel approaches with industry leaders and peers. International experts from the pharmaceutical and biotech industry, universities and the National Regulatory & Safety Institutes will cover topics of high interest around quality control, development...
With its unrivalled sensitivity, the PlasmaQuant ® MS Elite delivers the lowest detection limits of any ICP-MS when measuring both organic and inorganic species of arsenic in food and beverages. The high toxicity of inorganic arsenic means regular monitoring of food products is important. Various seafoods for example contain high levels of the less toxic organic arsenic species. Therefore, the dangers of arsenic depend not only on the total concentration, but also its chemical forms which vary in terms of toxicity and bioavailability....
Renishaw, a world leader in metrology and spectroscopy, reports on the use of its inVia confocal Raman microscope in the study of various diseases–with a major focus on childhood diseases–at the Children's Hospital of Michigan and Wayne State University. Dr Michael Klein is a surgeon with the Children's Hospital of Michigan–a part of the Detroit Medical Center (DMC)–and a researcher with the Department of Surgery at Wayne...
Photometrics, a manufacturer of high performance scientific cameras for life science applications, today announces the release of its new sCMOS camera, the Photometrics Prime. Prime is the first 4.2 Megapixel scientific CMOS camera available for life science research that actively defeats the negative impact of Poisson noise in low light images.
When specifying or purchasing any expensive and complicated piece of equipment it is essential to be able to ask the right questions in order to get the right answers and make an informed decision - a few minutes at the Autoclave Knowledge Bank could save your company time and money.
Blaze will be used to run virtual screening projects to translate Australia’s innovative research discoveries into new cancer drugs. “Cresset’s Blaze virtual screening platform was the obvious choice for us as it has a proven track record,” says Warwick Tong, Chief Executive Officer at CTx. “With access to a super computer at the Commonwealth Scientific and Industrial Research Organization (CSIRO) we now have the capability to run virtual...
Many drug treatments do not work in patients because of their poor ability to reach their intended targets that lie inside cells. To address this, researchers from Cardiff University’s Schools of Pharmacy and Pharmaceutical Sciences, and Biosciences, sought to improve the delivery of a relatively new class of drugs called biotherapeutics. These drugs include antibodies, such as Herceptin, that target breast and stomach cancer cells. Cancer cells often...
With the introduction of the new SKYSCAN™ 1275 highly automated, self-optimizing desktop X-ray microtomograph, Bruker puts class-leading imaging into the hands of materials and life scientists in both research and industrial applications, such as high-throughput 3D imaging in quality control and production process monitoring. The system takes advantage of new X-ray source technology and efficient flat-panel detectors to reduce...
The minister was visiting the site at the Queen Elizabeth University Hospital where the new Imaging Centre of Excellence (ICE) will be based. The ICE, supported by £16m of UK Government funding through the Medical Research Council as part of the Glasgow & Clyde Valley City Deal, will provide clinical research facilities which will be unique in the UK and create more than 200 new jobs for local people. The centre is expected to be...
A newly developed software interface allows seamless operation of the Connect stacker through the reader’s SparkControl™ software, helping to streamline laboratory workflows for greater productivity. The Connect is a versatile microplate stacker designed to offer fast, smooth transfer of plates to and from the host instrument. Already popular with users of Tecan’s Infinite® series microplate readers and HydroSpeed™ plate...