Company welcomes new customers with promise to provide seamless support for genomics research
Integrated DNA Technologies, the global leader in custom nucleic acid synthesis, has announced the acquisition of ValueGene, Inc. (“ValueGene”), an oligonucleotide synthesis services company based in San Diego, California. ValueGene offers custom DNA and RNA oligonucleotide synthesis products, including PAGE and HPLC purification and modification services. Dr Joseph A Walder, IDT founder and chief executive officer...
AMSBIO has launched a range of new TIGIT receptor products including a Jurkat cell line, Homogeneous assay kits and recombinant proteins for immunotherapy research.
Human T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is a receptor expressed on the surface of human T cells and NK cells that binds to CD155 and CD112 present on the surface of dendritic cells. The binding of TIGIT with CD155 or CD112 results in inhibition of T cell and NK cell activation. Antibodies and other agents that inhibit this signaling pathway have known to increase the immune response, particularly...
A new Derby-based, collaborative research project, which combines medicine and engineering, could improve the lives of thousands of people worldwide who are dependent on dialysis.
The Institute for Innovation in Sustainable Engineering (IISE) at the University of Derby has secured a prestigious £600,000 research grant from The MStart Trust, a Derby-based charity, to deliver the project. Positive long-term outcomes for patients on dialysis are significantly compromised by blood pressure instability during treatments, which can reduce their quality of life....
Workflow-driven software and expanded Thermo Fisher Cloud solutions provide accelerated route to discovery
Researchers looking to simplify compound identification, quantitation and complex data analysis now have access to a wide range of software and cloud solutions designed to allow users to analyze, share and discover unique insights in several applications, including proteomics, metabolomics, food safety and biopharmaceutical characterization. Built with customization in mind, Thermo Fisher Scientific’s life sciences...
Thermo Scientific Q Exactive BioPharma enables three powerful new protein characterization workflows on one instrument
Researchers performing biopharmaceutical characterization can now benefit from a single system from Thermo Fisher Scientific that enables three powerful workflows for the complete characterization of biotherapeutics. The new Thermo Scientific Q Exactive BioPharma MS/MS Hybrid Quadropole-Orbitrap mass spectrometer takes full advantage of the high-resolution, accurate-mass (HRAM) capabilities of the Orbitrap...
Avacta’s Affimer technology will be used to develop rapid lateral flow diagnostics for clinical applications
Avacta Group plc (AIM: AVCT) the developer of Affimer® biotherapeutics and research reagents, and Mologic, a specialist diagnostic development company, today announced they have formed a collaborative partnership to develop diagnostic tests against multiple targets of clinical interest for point of care (POC) testing, using Avacta’s Affimer technology. As stated at the time of Avacta’s interim results, establishing commercial relationships in the POC testing market is one of the Company’s key strategic objectives....
Autoscribe Informatics is delighted to announce a record order intake for its Laboratory Information Management Systems (LIMS) in the USA.
Results for the 6 months to April 2016 showed a total increase of orders of 161%, with April itself showing the highest ever order book for a single month. Autoscribe Informatics President, John Boother, said: “This is the latest step in a period of sustained growth for the company. It is a just reward for the effort we have put in to growing the business in the USA. We have increased our sales and support team there...
Thermo Fisher Scientific Inc., the world leader in serving science, strengthened its industry-leading analytical instruments platform with innovative systems designed to help pharmaceutical and biologics producers more efficiently discover and develop candidate drugs.
“The success of our innovation strategy is based on continuous collaboration with our customers,” said Marc N. Casper, president and chief executive officer Thermo Fisher Scientific. “Our mission is to enable our customers to make the world healthier, cleaner and safer, and we are committed to providing them with the most advanced analytical technologies to help them facilitate research and accelerate discovery....
With the impending legal requirements about to affect the life science and healthcare sectors, a leading decontamination expert has developed a quick overview to help explain the impact from the next phase of the Biocidal Products Regulation (BPR).
This new white paper written by John Chewins, director of the scientific & regulatory affairs at Bioquell, highlights that the introduction of the second phase of the BPR will mean some biocidal products currently legally placed on the market may no longer be legal....
Company now selling directly to customers in South Korea
Integrated DNA Technologies , the global leader in custom nucleic acid synthesis, has acquired MBiotech, Inc. (“MBiotech”), headquartered in Seoul, South Korea. MBiotech has been a distributor of IDT products for more than a decade. In its promotion of IDT products, MBiotech has successfully made IDT’s brand well-known throughout the South Korean peninsula....
Edinburgh Instruments have recently collaborated with the Departments of Physics in the Universities of Trento, Italy and Mumbai, India to work on the recombination dynamics of copper-nitrogen doped titanium oxide for use in water splitting applications.
Thin-films of copper-nitrogen-doped titanium oxide deposited by radio frequency magnetron sputtering were investigated by X-ray and photoluminescence spectroscopic techniques. In this work, time-resolved photoluminescence experiments clearly demonstrated that incorporation of copper and nitrogen inhibits the exciton radiative recombination of pure titanium oxide. This also resulted in increased mean lifetimes which...
Antibodies are tremendously useful and versatile tools and they have found use in many areas of life science research.
However, antibodies can be difficult to make and are used in inherently complex biological systems. Consequently, they can be prone to quality issues: batch-to-batch variability, lack of specificity, or poor sensitivity. The impact of this can be substantial, both financially and scientifically as identified in recent studies. Learn how at Abcam, we are raising industry quality standards by using newer and improved technology to manufacture and...
Trajan Scientific and Medical (Trajan) announces two advancements in the development of devices and components for nano-electrospray ionization mass spectrometry (nanoESI-MS), in collaboration with the University of Adelaide in Australia, and with Queen’s University and Université Laval in Canada.
Trajan and the University of Adelaide’s Institute for Photonics and Advanced Sensing (IPAS) have been awarded an A$0.5 million Australian Research Council (ARC) Linkage grant to create glass capillaries and tubes with advanced geometries to enhance the sensitivity of mass spectrometry....
Protagen AG, a leading specialist in the development of novel diagnostic tests and companion diagnostics in the autoimmune field, today announced the launch of its first CE marked diagnostic assays Multilisa® CENP-B and Multilisa® Scl-70 ELISA to aid in the diagnosis of Systemic Sclerosis (SSc).
The Protagen Multilisa® SSc program combines novel and proprietary markers with existing diagnostic standards to help understand the condition at a molecular level. Multilisa® CENP-B and Multilisa® Scl-70 are intended for the semi-quantitative determination of IgG antibodies specific for the CENP-B and Scl-70 proteins. Analysis of autoantibodies against both proteins is part of the guidelines for the diagnosis and...
Glycosylation is one of the most prevalent co- and post-translational modifications of human proteins and is known to affect the protein properties.
Glycosylation is known to be involved in many different diseases. The sialic acids at the end of the glycan chain serve as a binding site for toxins, pathogens and human lectins in a linkage-specific manner having great biomarker potential. During the development and production of biopharmaceuticals glycosylation is a critical quality attribute and therefore has to be monitored. It is known that different cell culture conditions can lead to different...
The human cell culture specialists showcase innovative tools and applications for disease modelling and drug discovery
Axol Bioscience, a biotechnology company specialising in the supply of human induced pluripotent stem cell (iPSC)-derived cells has expanded its range of drug discovery and disease modelling tools. This includes: Human iPSC-Derived Atrial Cardiomyocytes, Human iPSC-Derived Endothelial Colony Forming Cells (ECFCs) and axolGEMs (Genetically Edited Models)...
Read MoreScientists Identify Drugs to Target Jul 4, 2016
New research, by the Universities of Glasgow and Manchester, has revealed an ‘Achilles heel’ of Chronic Myeloid Leukaemia (CML) and found drugs to successfully target this weakness and eradicate the disease in mice.
The study, which is published in Nature today, analysed both CML and normal blood stem cells and found two proteins that were key to the survival of CML stem cells. The group, which has been working on this research for more than six years, then developed a drug combination to simultaneously target these critical proteins and kill the cancer stem cells, while largely sparing normal cells...
Bruker introduces rapifleX™, the highest performance MALDI-TOF/TOF mass spectrometer, which had been shown as work-in-progress to early adopters at HUPO 2015.
The rapifleX is by far the most advanced TOF/TOF system today, and was re-designed from the ground up to meet today’s highest demands for in-depth intact and top-down protein characterization, and high-performance, high-throughput mass spectrometry imaging (MSI). With its next-generation TOF/TOF ion optics and smartbeam® 10 kHz proprietary laser technology, the rapifleX system now offers...
Tecan and CellSpring, a biotech spin-out from ETH Zurich, have announced a co-marketing agreement to automate the 3D Bloom® platform on a Freedom EVO® workstation.
This latest collaboration will further extend Tecan’s automated 3D cell culture portfolio, allowing scientists to take advantage of a high throughput technology with an extended cell viability period of at least seven days in the assay matrix. The adaptive 3D Bloom Biopolymer Platform is compatible with all cell types and is ideal for...
Horizon Discovery Group plc has announced that QIAGEN N.V. will be offering an extensive package of quality control data, generated through the application of Horizon’s Reference Standards, with its GeneReader NGS System.
Deal demonstrates the impact Horizon's Reference Standards are having in supporting the rapidly growing Next Generation Sequencing (NGS) market
Future joint collaborations are expected as work continues to unlock the full clinical and research potential of both technologies
Lab Innovations 2016 returns to the NEC, Birmingham, for its fifth edition. The show, which has established itself as the UK’s only event dedicated to laboratory professionals, will take place on 2 & 3 November 2016.
Laboratory professionals from a wide range of industry sectors will flock to the show to source the latest products and services on the market. Last year saw decision makers from big names such as Sainsbury’s, Kellogg’s, Rolls Royce and 3M walk the show floor. The show will also provide visitors with the opportunity to attend free educational seminars and network with like-minded individuals, often presenting numerous...
For a limited time NanoHybrids is accepting applications for a chance to win a supply of their top Gold Nanoparticles to enhance imaging project results.
NanoHybrids has launched a contest to give promising research free premium gold nanoparticles. Targetingbiomedical imaging applications, the contest offers free nanoparticles as well as various services to winning study or research proposals. Called the NanoHybrids Imaging Research Contest, applications are being accepted now until July 31st through the NanoHybrids website....
Integrated DNA Technologies, the global leader in custom nucleic acid synthesis, has announced the acquisition of ValueGene, Inc. (“ValueGene”), an oligonucleotide synthesis services company based in San Diego, California. ValueGene offers custom DNA and RNA oligonucleotide synthesis products, including PAGE and HPLC purification and modification services. Dr Joseph A Walder, IDT founder and chief executive officer...
Human T-cell immunoreceptor with Ig and ITIM domains (TIGIT) is a receptor expressed on the surface of human T cells and NK cells that binds to CD155 and CD112 present on the surface of dendritic cells. The binding of TIGIT with CD155 or CD112 results in inhibition of T cell and NK cell activation. Antibodies and other agents that inhibit this signaling pathway have known to increase the immune response, particularly...
The Institute for Innovation in Sustainable Engineering (IISE) at the University of Derby has secured a prestigious £600,000 research grant from The MStart Trust, a Derby-based charity, to deliver the project. Positive long-term outcomes for patients on dialysis are significantly compromised by blood pressure instability during treatments, which can reduce their quality of life....
Researchers looking to simplify compound identification, quantitation and complex data analysis now have access to a wide range of software and cloud solutions designed to allow users to analyze, share and discover unique insights in several applications, including proteomics, metabolomics, food safety and biopharmaceutical characterization. Built with customization in mind, Thermo Fisher Scientific’s life sciences...
Avacta Group plc (AIM: AVCT) the developer of Affimer® biotherapeutics and research reagents, and Mologic, a specialist diagnostic development company, today announced they have formed a collaborative partnership to develop diagnostic tests against multiple targets of clinical interest for point of care (POC) testing, using Avacta’s Affimer technology. As stated at the time of Avacta’s interim results, establishing commercial relationships in the POC testing market is one of the Company’s key strategic objectives....
Results for the 6 months to April 2016 showed a total increase of orders of 161%, with April itself showing the highest ever order book for a single month. Autoscribe Informatics President, John Boother, said: “This is the latest step in a period of sustained growth for the company. It is a just reward for the effort we have put in to growing the business in the USA. We have increased our sales and support team there...
This new white paper written by John Chewins, director of the scientific & regulatory affairs at Bioquell, highlights that the introduction of the second phase of the BPR will mean some biocidal products currently legally placed on the market may no longer be legal....
Integrated DNA Technologies , the global leader in custom nucleic acid synthesis, has acquired MBiotech, Inc. (“MBiotech”), headquartered in Seoul, South Korea. MBiotech has been a distributor of IDT products for more than a decade. In its promotion of IDT products, MBiotech has successfully made IDT’s brand well-known throughout the South Korean peninsula....
Thin-films of copper-nitrogen-doped titanium oxide deposited by radio frequency magnetron sputtering were investigated by X-ray and photoluminescence spectroscopic techniques. In this work, time-resolved photoluminescence experiments clearly demonstrated that incorporation of copper and nitrogen inhibits the exciton radiative recombination of pure titanium oxide. This also resulted in increased mean lifetimes which...
However, antibodies can be difficult to make and are used in inherently complex biological systems. Consequently, they can be prone to quality issues: batch-to-batch variability, lack of specificity, or poor sensitivity. The impact of this can be substantial, both financially and scientifically as identified in recent studies. Learn how at Abcam, we are raising industry quality standards by using newer and improved technology to manufacture and...
Trajan and the University of Adelaide’s Institute for Photonics and Advanced Sensing (IPAS) have been awarded an A$0.5 million Australian Research Council (ARC) Linkage grant to create glass capillaries and tubes with advanced geometries to enhance the sensitivity of mass spectrometry....
The Protagen Multilisa® SSc program combines novel and proprietary markers with existing diagnostic standards to help understand the condition at a molecular level. Multilisa® CENP-B and Multilisa® Scl-70 are intended for the semi-quantitative determination of IgG antibodies specific for the CENP-B and Scl-70 proteins. Analysis of autoantibodies against both proteins is part of the guidelines for the diagnosis and...
Glycosylation is known to be involved in many different diseases. The sialic acids at the end of the glycan chain serve as a binding site for toxins, pathogens and human lectins in a linkage-specific manner having great biomarker potential. During the development and production of biopharmaceuticals glycosylation is a critical quality attribute and therefore has to be monitored. It is known that different cell culture conditions can lead to different...
Axol Bioscience, a biotechnology company specialising in the supply of human induced pluripotent stem cell (iPSC)-derived cells has expanded its range of drug discovery and disease modelling tools. This includes: Human iPSC-Derived Atrial Cardiomyocytes, Human iPSC-Derived Endothelial Colony Forming Cells (ECFCs) and axolGEMs (Genetically Edited Models)...
The study, which is published in Nature today, analysed both CML and normal blood stem cells and found two proteins that were key to the survival of CML stem cells. The group, which has been working on this research for more than six years, then developed a drug combination to simultaneously target these critical proteins and kill the cancer stem cells, while largely sparing normal cells...
The rapifleX is by far the most advanced TOF/TOF system today, and was re-designed from the ground up to meet today’s highest demands for in-depth intact and top-down protein characterization, and high-performance, high-throughput mass spectrometry imaging (MSI). With its next-generation TOF/TOF ion optics and smartbeam® 10 kHz proprietary laser technology, the rapifleX system now offers...
This latest collaboration will further extend Tecan’s automated 3D cell culture portfolio, allowing scientists to take advantage of a high throughput technology with an extended cell viability period of at least seven days in the assay matrix. The adaptive 3D Bloom Biopolymer Platform is compatible with all cell types and is ideal for...
Deal demonstrates the impact Horizon's Reference Standards are having in supporting the rapidly growing Next Generation Sequencing (NGS) market
Laboratory professionals from a wide range of industry sectors will flock to the show to source the latest products and services on the market. Last year saw decision makers from big names such as Sainsbury’s, Kellogg’s, Rolls Royce and 3M walk the show floor. The show will also provide visitors with the opportunity to attend free educational seminars and network with like-minded individuals, often presenting numerous...