IonSense, the leading provider of Direct analysis in real time mass spectrometry (DART) for rapid mass spectral analysis of a large variety of samples, has announced its ground-breaking DART-MS technology has been selected as part of a new drug screening program, piloting in five states across the United States. The pilot program is testing drugs and drug paraphernalia using highly accurate fast detection mass spectrometry enabled by IonSense’s DART, to identify the contents of drugs within minutes...
Do you want to know how to choose the right column for your separation? Then check out our new technical note focusing on how to select the perfect LC column! In this technical note, the differences in selectivity and resulting separation behaviour of various phases are shown. Primary and secondary interactions between the analyte and stationary phase are explained for each phase. Two application examples demonstrate how these interactions affect your analysis...
Insightful Science, the software company enabling the Cloud for Scientific Discovery, announce that it has completed the transaction to acquire Protein Metrics, Inc., a leading provider of biopharmaceutical protein characterization and proteomics analysis software. The acquisition expands the Company’s R&D value chain to widen the biopharmaceutical protein analysis arena, unblocking data analysis bottlenecks currently associated with large-scale protein studies...
Get to know the significant advantages of YMC-Triart Bio C4! This new application note shows why this stationary phase is the ideal choice for the analysis of cyclic peptides. These compounds are highly valuable drug candidates since their cyclic ring structure provides various advantages over their linear counterpart. This is the reason why they are increasingly becoming the focus in biopharmaceutical research...
BioChromato Inc. reports how their ionRocket sample preparation device, used in combination with Direct Analysis in Real Time Mass Spectrometry (DART®-MS), enables routine analysis of low solubility, high molecular weight compounds. Phthalocyanine based pigments are widely used for organic semiconductors and organic electroluminescence displays due to their clearness, high light stability, and durability. However, the chemical structure of Phthalocyanine based pigments are difficult to analyze...
Food industry, government and contract testing laboratories performing food safety analysis can now benefit from a new portfolio that offers cost-effective, robust Solid-Phase Extraction (SPE) solutions to support food safety workflows and meet regulatory requirements across Europe, Asia and the Americas. The Thermo Scientific QuEChERS product line provides an easy-to-use, sample preparation workflow...
The new 2022 version of TESTA Analytical’s liquid chromatography flowmeter allows users to now set the optimal integration time to suit different applications. For example - sampling data every 0.1 seconds is optimal for real-time monitoring of HPLC pump performance whereas sampling data every 10 seconds is best for absolute flow rate calibration...
With chemists engineering new “designer drugs” everyday, law enforcement and regulatory bodies need testing to quickly and accurately determine the composition of these compounds. This study will present a static headspace method for rapidly determining drug components for use in forensic applications. A HT3 Headspace Analyzer will be used to examine bath salt samples for the presence of mephedrone (MPD) and methylenedioxypyrovalerone (MPDV or MDPK) by GC/MS.
Agilent Technologies Inc. has announced that the Agilent Cary 3500 UV-Vis Spectrophotometer is now compatible with the Agilent OpenLab software suite of products. The Cary 3500 UV-Vis data can now be managed, protected, and stored in a secure central database, helping to meet global regulatory requirements. A pharma lab manager survey indicated that data integrity is a top concern....
BioChromato Inc. has published an interview that describes a new bioremediation technique developed by a leading Environmental Research Center and how the Smart Evaporator C1 offers a productive tool for preparing microbial degradation culture media for analysis. The novel bioremediation technique, based upon patented degrading microorganisms impregnated on carbonized wood, has been demonstrated to detoxify persistent organic pollutants (POPs) that cannot be decomposed by natural processes in soil.
A diffraction grating is used to separate polychromatic light into its constituent wavelengths. In a Raman spectrometer diffraction gratings are used to separate the constituent wavelengths of the collected Raman scatter onto different pixels of the CCD camera for detection. All Raman spectrometers will require at least one diffraction grating and will frequently be configured to contain more than one to allow the user optimum grating selection for their samples and excitation wavelength(s).
YMC-Triart C18 UHPLC columns with an ID of 1 mm are the ideal choice for high sensitivity LC/MS analyses. In this new application note, the screening of 6 antineoplastic drugs is shown. This analysis requires the highest sensitivity since even the smallest amounts of these drugs need to be detected due to their adverse very serious, life-threatening effects. By choosing a high efficiency column with a small internal diameter of 1 mm and coupling it to mass spectrometry the benefit becomes clear: excellent peak shapes – also for low sensitivity compounds!
Are you interested to find current tools and practical solutions to preparative and process chromatographic separations? Are you wanting to learn how to successfully optimize chromatography processes and minimize costs for the best economic production? Are you looking for a conference with strong scientific content, a robust program, presentations by world renowned experts, lectures by young scientists, workshops offering great training opportunities..
Testa Analytical Solutions e.K reports on growing interest in OEM versions of its Differential Refractive Index (DRI) detector to enhance the performance of both HPLC and GPC/SEC systems. Charlotte Stentzler, Technical Manager of Testa Analytical said "We have invested in stock components to enable us to offer our high performance DRI detectors, made here in Germany, on short delivery times....
The call for submissions aims at raising the visibility of research results that have been achieved with Analytik Jena equipment and technology – especially with a view to its potential for applications and new possibilities in the field. The panel will accept submissions of findings and applications that have been published within the past three years. The prize for the best submissions will be 1000 euros for personal use...
Metrohm is excited to announce the opening of a new office in New Jersey. The new facility will house development, production and manufacturing space for Metrohm Group companies Innovative Photonic Solutions and B&W Tek. It is located in the heart of the U.S. pharmaceutical market and will also serve as a field office for Metrohm USA. Metrohm has been growing its footprint in the spectroscopy market in recent years and is proud to announce its latest investment...
The use of only one SEC column brings a certain limitation due to its dedicated pore size and a limited column volume. By coupling two columns this hurdle can be overcome. Doubling the column length implies a doubled column volume which results in improved resolution of peaks. Additionally, if using two columns with different pore size, the applicable molecular weight range can be increased significantly....
A Schlenk Line is a tubular glass apparatus commonly used in chemistry or material laboratory research to carry out experiments under a vacuum and an inert atmosphere (like nitrogen or argon). It is used when samples are sensitive to air/moisture and the vacuum is also often used to remove the last traces of solvent from a sample. A Schlenk Line typically contains a dual glass manifold with multiple ports; the number of ports is configurable....
Porvair Sciences has published an in-depth application report demonstrating how their Microlute® CP Reverse Phase Solid Phase Extraction (SPE) microplates provide a robust and highly reproducible SPE LC-MS sample preparation methodology for a range of neutral, acidic, and basic analytes. As a sample preparation method - Solid Phase Extraction is widely acknowledged as a 'go to' tool for the clean-up of samples before analysis by hyphenated techniques such as LC/MS or GC/MS...
SCION Instruments announce the launch of the next generation of GCs designed for the ultimate user-experience. Combining high performance, productivity and flexibility, the launch of the GC8300 and GC8500 takes Scion’s gas chromatographers to the next level. Both the GC8300 and GC8500 benefit from an improved, intuitive user interface with larger 10” full colour touch screen providing improved visual quality and a superior overview of all instrument status, access to methods and automation...
Thermo Fisher Scientific Inc., the world leader in serving science, announce innovative proteomics solutions and a series of co-marketing agreements with industry experts, advancing the throughput, comprehensiveness and quality of proteomics workflows for applications such as single-cell studies and translational research. The company will showcase these relationships, as well as new additions to its industry-leading offering of mass spectrometry (MS) and chromatography instruments, during the Human Proteome Organization (HUPO) Reconnect event...
TESTA Analytical Solutions e.K has introduced new laser options for its HK Series differential refractometer to enable precise determination of specific refractive index increment (dn/dc) at the same wavelength as the light scattering application under investigation. Light scattering is a tried and trusted method for measuring molecular weight and therefore a widely used tool for analyzing biopolymers, polymers and proteins....