Thermo Fisher Scientific has developed a simple, efficient, sensitive, and reproducible capillary ion chromatography (IC) method for determining thiosulfate and pyrophosphate in crayfish wash powder.
Application Note 1088: Determination of Thiosulfate and Pyrophosphate in Crayfish Wash Powder demonstrates that this application is easily executed using a Reagent-Free™ IC system capable of high-pressure IC controlled by data management software. The analyst simply adds water and samples to separate thiosulfate and pyrophosphate on a specialized anion-exchange column, the Dionex IonPac AS19 capillary column, thus...
The MiniVap™ Blowdown Sample Concentrator from Porvair Sciences is purpose designed for research and development departments that need to dry smaller numbers of individual microplates or HPLC vials.
The compact MiniVap is simple to operate and requires minimal ongoing maintenance. To install - a MiniVap requires only connection to a gas supply and standard mains socket. Safety of operation is ensured as the CE marked unit fits into all fume cupboards. Offering manual fine control of needle depth, gas temperature and flow rate - the affordably priced MiniVap can be easily optimised to produce faster drying times than other entry level lab evaporators. MiniVap takes just minutes to...
Magritek, a leading worldwide provider of compact NMR and MRI instruments, have demonstrated the use of their Spinsolve benchtop NMR spectrometer to perform and monitor chemical reactions on-line.
As costs for energy and raw materials continue to rise, it becomes more critical for chemists to be able to mimic a reaction or to quantify the parameters required to produce a final product without the difficulty and expense of using production facilities. To be able to recreate a production process on a lab bench is therefore highly desirable for many chemists. The Magritek Spinsolve high-resolution benchtop NMR spectrometer is a...
Thermo Fisher Scientific, the world leader in serving science, today unveiled a new high performance liquid chromatography system designed from the ground up to provide new levels of performance, productivity and usability when used as a standalone system or with the latest mass spectrometers.
The new Thermo Scientific Vanquish UHPLC looks different from standard UHPLC systems, and there are benefits to its clean design. The monolithic case contains an instrument that combines the ruggedness of an integrated system with the flexibility and serviceability of a modular system. Vanquish stands about 25 percent lower than comparable modular stacks for safety and convenience in the laboratory...
Thermo Fisher Scientific has developed a simple, rapid, reliable, and accurate high-performance liquid chromatography (HPLC) method for the simultaneous determination of amlodipine and besylate in an amlodipine besylate drug substance.
Application Note 1087: Simultaneous Determination of Amlodipine and Its Counterion Besylate by HPLC demonstrates that this method requires only 8 minutes per analysis using a column designed for pharmaceutical analysis and ultraviolet detection. In addition, combining the analysis of the active pharmaceutical ingredient (API) and counterion into a single method saves times, reduces mobile phase consumption, and minimizes waste. Amlodipine besylate is a...
AMSBIO announces MagSi-Direct - a revolutionary technology that brings the power, simplicity, and convenience of magnetic separation to researchers involved in cell biology, protein chemistry, flow cytometry, diagnostics development and many other fields
MagSi-Direct provides a convenient and efficient way to attach virtually any biomolecule to nanoscopic paramagnetic beads. It is particularly suited for exploiting interactions between a biomolecule and its binding partners. With MagSi-Direct, you can start with a molecule of interest, attach magnetic beads to it, and then use a magnet to isolate that molecule from any desired reaction mixture, together with any other molecules, complexes, or even intact cells to...
The HT-4X evaporator from Genevac has been specifically designed for drug discovery laboratories, from medicinal chemistry through to purification and metabolism studies.
Built to the highest specifications the HT-4X makes demanding applications routine. Corrosive vapours such as trifluoroacetic acid can be routinely removed by the standard system and optional facility is provided for fast sample lyophilisation. An innovative built-in dual chamber refrigerated condenser accelerates speed of evaporation, even for high boiling point solvents such as DMSO. In addition, efficient chamber cooling between runs protects thermally...
For precise, reproducible and error-free sieving processes
The new Octagon 200CL competes with the most advanced sieve shakers in the world. Several unique features have been developed specifically for this machine, including the ‘Closed Loop’ amplitude control for ultimate reproducibility. The Octagon 200CL is designed to work with Endecotts’ SieveWare, the new software for easy evaluation and documentation of the sieving process.
Read MoreFinneranJul 28, 2014
Finneran storage boxes and cell dividers are designed as an economical storage solution for cryovials, cold storage sample vials or centrifuge tubes.
Available in white or yellow, the boxes and dividers are constructed of a sturdy, durable, cardboard with a moisture repellent coating that protects the storage box from the affects of liquid nitrogen or condensation from refrigerators or freezers. Unique chromatography sample vials, closures and accessories manufactured by J.G. Finneran Associates are available internationally from a network of laboratory dealers.....
Latest chromatography products available from Hichrom
Kromasil EternityXT UHPLC/HPLC Columns
Kromasil EternityXT columns are Akzo Nobel’s next generation Eternity UHPLC and HPLC columns. These columns show excellent mechanical and chemical stability, producing excellent separation and loadability at low, medium and high pH (from pH 1 – 12)....
The most efficient particle sizing in the micron range
The new Air Sizer 200 is ideal for sieving very fine dry particles, which require efficient dispersion and desagglomeration via air jet technology (e.g. electrostatic material). It is also the perfect instrument to quickly provide a sieve cut of powdered materials. The Air Sizer 200 is easy to use, extremely efficient and provides accurate and reproducible results.
The EZ-2 Elite Centrifugal Evaporator from Genevac has been designed to provide unmatched final drying of stubborn samples and fast lyophilisation of HPLC fractions
Benefiting from a high performance scroll pump, that delivers deep vacuum, the EZ-2 Elite is able to routinely remove even very high boiling solvents such as DMSO and NMP. In addition internal heating of vapour duct and system components ensures that such challenging solvents only collect in the SpeedTrap™ condensor, and not anywhere else. The SpeedTrap condenser on the EZ-2 Elite comes the benefit of automatic defrost and drain technology. The EZ-2 controls the SpeedTrap and...
Thermo Fisher Scientific has developed a high-performance anion-exchange chromatography with pulsed amperometric detection method, based on AOAC Official Method 2011.18, to determine free and bound myo-inositol in infant formula and adult nutritionals.
Application Note (AN) 1083: Determination of Myo-Inositol (Free and Bound as Phosphatidylinositol) in Infant Formula and Adult Nutritionalsdemonstrates a column-switching technique used to remove strongly retained carbohydrates in the sample, thereby reducing run time. Pulsed amperometric detection with a gold on polytetrafluoroethylene disposable electrode offers high sensitivity while eliminating the need for sample derivatization and electrode polishing...
Bruker has demonstrated a new sample preparation method for analysis of pesticides in fruits and vegetables, using the EVOQ liquid chromatography mass spectrometer triple quadruple (LC-MS/MS) and SCION gas chromatography mass spectrometer triple quadruple (GC-MS/MS).
A continuing challenge in multi-residue MS analysis is finding a sample preparation method that is as easy, fast and cost-efficient as possible. The US Food and Drug Administration (FDA) has modified a QuEChERS (quick, easy, cheap, effective, rugged and safe) protocol, which can be used to extract multiple classes of pesticides from a variety of samples. Using the EVOQ and SCION, Bruker has shown the...
No tiny screen, external PC, or limited onboard UV-Vis protocols here! Epoch 2 provides a 10" color touch screen, full-featured Gen5™ Data Analysis Software and precision optics at a smart price. This new workstation is ideal for reading microplates, cuvettes, BioCells and micro-volumes for quick and simple measurements of virtually all photometric applications. Easily view data, and export via WiFi, Bluetooth or flash drive. Epoch 2 keeps it simple...
Thermo Fisher Scientific has demonstrated that a hydrophobic interaction chromatography (HIC) column, the Thermo Scientific™ ProPac™ HIC-10 column, is suitable for separating low-concentration species of an intentionally oxidized MAb from the native MAb.
The same method can be used to separate the papain fragments from the intentionally oxidized MAb, as well as the papain fragments of the native MAb. Application Note 1084: Separation of Papain Digests of Oxidized Monoclonal Antibodiesdetails how the ProPac HIC-10 column can be used to resolve antigen-binding fragments (Fab) and nonantigen-binding fragments (Fc) generated by papain digestion, as well as oxidized Fab/Fc from native Fab/Fc...
VICI Metronics’ Dynacalibrator® Model 150 is a constant temperature system designed to generate precise ppm or ppb concentrations of chemical compounds in a gas stream, using permeation devices as the trace gas source.
It is used as a reference for the calibration of gas chromatography instruments and in other instruments that measure gas concentrations. This light-weight unit is a compact calibrator capable of delivering the precise concentrations required. A passivated Inertium® coated stainless steel permeation chamber houses the permeation device(s), with measured inert carrier gas sweeping the calibration gas/vapor from the chamber...
Thermo Fisher Scientific has developed a fast and robust ion chromatography (IC)-based method for the determination of chloride and sulfate in adenosine.
Application Note 1075: Ion Chromatography Assay for Chloride and Sulfate in Adenosine demonstrates that this method supports high sample throughput with a run time of just 3.5 min, requires no toxic chemicals, and can replace the U.S. Pharmacopeia monograph’s existing turbidity-based assays of these compounds. A high-pressure IC system (Thermo Scientific™ Dionex™ ICS-5000+ HPIC™ IC system) combined with a...
Warwick Analytical Service (WAS) has introduced the Quantitative ICP-Scan, a new service that determines the levels of 67 different elements at low part per million making it ideal for analysing unknown or suspect contamination samples.
The service is competitively priced and a great starting point in determining elemental sample composition. The 67 elements covered by this proprietary WAS ICP methodology range from Silver (Ag) through to Zirconium (Zr)**. The WAS Quantitative ICP Scan Service provides information on elements present at 10-100 ppm right up to greater than 1% w/w. Measured intensities are compared to intensities of traceable standards to obtain the...
The High-Throughput DynaPro Plate Reader Utilizes Dynamic Light Scattering to Identify Most Promising mAb Buffer Conditions Prior to Extended Stability Testing
Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation, is pleased to highlight a study recently authored by Martin Skov Neergaard from the Faculty of Health and Medical Sciences at the University of Copenhagen, “Protein-Protein Interactions Investigated by DLS: Determination at High and Low Protein Concentration.” This article outlines the benefits of quantifying protein-protein interactions (PPI) using...
This comprehensive new medical compendium commemorates ten years of Sebia’s excellence in the field of hemoglobin separation using capillary electrophoresis
Sebia, a market leader in protein electrophoresis and tests for the diagnosis of hemoglobin disorders, announces today the debut of its Hemoglobins Atlas. This tool, which has been developed for the first time, is dedicated to helping Sebia’s capillary electrophoresis users orientate their diagnosis of hemoglobinopathies. Hemoglobin electrophoresis is an established technique routinely used in clinical laboratories for screening samples for...
Trajan Scientific and Medical (Trajan) will complete the integration of SGE Analytical Science (SGE) at all major operational centers in Australia, Europe, the US and Asia, as of July 1, 2014, when SGE entities will register new Trajan business names.
For workers in many laboratories around the world, SGE is synonymous with the highest quality in chromatography components and consumables. The company has established a leading reputation over the last 50 years. The SGE brand will live on and continue to grow in this field, supported by Trajan and its well-established network of distributors. Stephen Tomisich, Trajan’s Chief Executive Officer said, “We are proud to build on...