Suppression plays a key role in ion-exchange chromatography and conductivity detection. It is widely used, e.g., for the analysis of anions and organic acids.

Metrohm is pleased to present a new brochure putting the theoretical aspects and practical benefits of suppression in ion chromatography in a nutshell.

Suppression as a practical solution for ion chromatography

• decreases the background conductivity of the eluent
• minimizes baseline noise
• optimizes the signal-to-noise ratio
• increases the sensitivity of the measuring system

Genevac announces a proprietary “odour reduction” function for its EZ-2 evaporator which enables it to be sited on the open bench rather than taking up valuable fume hood space.

Many solvent evaporators are routinely sited inside fume extraction hoods because residual solvent vapour, remaining in the chamber at the end of a run, can expose the operator to potentially harmful odours when the system is opened. The EZ-2’s Reduce Odour function automatically adds a repeated vent and vacuum cycle to the end of a method, which purges the evaporation chamber of residual solvent vapours...

Thermo Fisher Scientific has developed a high-performance liquid chromatography method to determine 20 polycyclic aromatic hydrocarbons (PAHs) in environmental waters using on-line solid-phase extraction (SPE) for sample preparation.

Analytik, leading suppliers of innovative analytical instrumentation, report on how the LabSpec Vis-NIR portable spectrometer from PANalytical Boulder (formerly ASD Inc) is being used to study historic materials. 

Analytik have supplied LabSpec Vis-NIR spectrometers in the world of heritage research where non-destructive identification of materials is vital both in terms of preservation and restoration. Systems are in use in museums, galleries, libraries and historic properties where applications include the dating of historic parchments and the analysis of pigments on manuscripts.  Dr Craig Kennedy is a senior lecturer in the School of the...

When it comes to pursuing breakthroughs in proteomics research, there’s no such thing as too much scanning speed, as long as data quality remains high.

Addressing this demand is the latest addition to the best-selling Q Exactive family of Thermo Scientific liquid chromatography-mass spectrometry (LC-MS) systems, the Thermo Scientific Q Exactive HF instrument. The Thermo Scientific Q Exactive HF system is making its debut at the 62^nd ASMS Conference on Mass Spectrometry and Allied Topics, booth 127, and at the Holiday suite in the Hilton Baltimore Hotel...

As protein-based drugs become more important in treating major diseases, producers face the critical challenge of deeply characterizing these highly-complex molecules for efficacy and safety, as well as to meet quality requirements.

Now there’s a new software tool designed to increase the speed, quality and confidence in comprehensive biotherapeutic protein characterization useful for drug development and production quality control. Thermo Scientific PepFinder software is making its debut at the 62^nd ASMS Conference on Mass Spectrometry and Allied Topics, booth 127, and at the company’s hospitality suite: Holiday, Baltimore Hilton. PepFinder software is designed to...

A new brochure from Malvern Instruments details the range of detectors available for Gel Permeation/Size Exclusion Chromatography (GPC/SEC).

It also provides scientists with the background required to choose the detector array most appropriate to maximizing information flow and experimental productivity. Available as standalone units, or as part of a fully integrated Viscotek multi-detection GPC/SEC system, Malvern’s GPC/SEC detectors provide highly accurate analysis of polymer and protein macromolecular features, such as molecular weight, and combine to offer advanced insight into molecular structure...

Laboratories analyzing food, the environment, and biological samples for compounds like dioxins, PCBs, pesticides, steroids and other challenging analytes now have access to a new generation of GC-MS/MS from Thermo Fisher Scientific, designed to deliver more sensitivity at faster speeds than its predecessor.

The new Thermo Scientific TSQ 8000 Evo triple quadrupole GC-MS is making its debut at the 62^nd ASMS Conference on Mass Spectrometry and Allied Topics at the company’s hospitality suite: Holiday, Baltimore Hilton. The TSQ 8000 Evo system improves on the features of its predecessor, the TSQ 8000, with new EvoCell technology, demonstrated in company-run experiments to triple selected reaction monitoring (SRM) transition rates without compromising sensitivity...

Novel Program Increases Lab Accuracy and Unknown Compound Identification with Single Quadrupole Instrumentation

Cerno Bioscience and Agilent Technologies, Inc. (NYSE: A) today announced Agilent will distribute Cerno Bioscience’s MassWorks™ calibration and analysis software with all Agilent GC/MSD systems. This novel calibration technology increases the mass accuracy of Agilent's single quadrupole GC/MSD to enable unknown compound identification. This process normally requires more complex instruments such as Time-of-Flight (TOF) mass spectrometers "Making Cerno MassWorks directly available to GC/MSD users through Agilent channels opens the qualitative power of accurate mass information to...

Laboratories analyzing environmental, clinical research/toxicological, and food samples have a powerful new data tool expected to save time and money while identifying compounds with high levels of confidence.  

Thermo Fisher Scientific announces its high resolution accurate mass (HRAM) spectral library at the 62^nd ASMS Conference on Mass Spectrometry and Allied Topics. “This is a true library with full, high-resolution spectra for every compound it contains,” said Jennifer Massi, program manager, environmental and food safety for Thermo Fisher Scientific. “In fact, we ran multiple MS/MS spectra for each compound, and each was analyzed at multiple collision energies. This is designed to enhance method flexibility and confidence in results.”...

Waters Introduces Xevo G2-XS QTof and Xevo TQ-S micro Mass Spectrometers, Taking Benchtop Quantitative and Qualitative MS Applications to New Levels

Company also Expands ionKey/MS System to SYNAPT and Xevo Time-of-Flight Mass Spectrometers with New UPLC-Grade iKey Chemistries.
Waters Corporation (NYSE:WAT) today introduced two new Xevo® mass spectrometers and expanded the ionKey/MS System at the 62nd conference of the American Society of Mass Spectrometry (ASMS). The Waters® Xevo G2-XS mass spectrometer, a new high performance benchtop quadrupole time-of-flight (QTofTM) mass spectrometer, and the Xevo TQ-S micro, a new and compact benchtop tandem quadrupole mass spectrometer, take...

J.G. Finneran's Ultra Low Bleed Aluminum Seals and 9mm R.A.M.™ Caps are lined using LCMS high purity septa. 

The ultra low bleed septa are ideal for very sensitive applications such as Mass Spec or when multiple injections are required.  Our Ultra Low Bleed Septa eliminates particulates with no interfering peaks.  Aluminum seals are available in 11mm and 20mm crimp finish. The 9mm R.A.M.™ short thread closures with a smooth or ribbed finish, are available with either a friction fit or bonded ultra low bleed PTFE/Silicone Septa....

Its space saving stackable design allows you to make the most of your lab space and the modular design allows for different combinations to suit single and multiple GC applications.

Looking to the future, the F-DGSi Modular Alliance Series can also accommodate Helium to Hydrogen conversion as natural resources run low and costs rise, with our high purity H2 generator model WM-H2. Hydrogen provides many advantages over helium including, higher resolution, shorter run times, longer column life, and cost savings. Many instrument manufacturers now provide resources to make switching carrier gas easier....

13mm and 25mm Syringe Filters, from J.G. Finneran Associates, are manufactured using polypropylene medical-grade housings with Luer-Lock and Luer-Slip fittings in compliance with ISO 594-1. 

Each filter is sealed, using an external ring insert, to maintain the membrane integrity and best performance.  Filters are color-coded for easy identification of the filter’s membrane type. The Certified Filters are supplied with a Certificate of Quality, batch-to-batch, to guarantee product performance and quality. The filters are visually inspected following quality specifications. Each batch of filters is tested for external dimensions, bubble point, filter integrity, water flow rate, UV extractable, and compliance with all technical procedures, manufacturing specifications, and quality controls for release. Tests are performed by an independent laboratory....

J.G. Finneran Associates is a highly recognized, respected and independent, family-owned and operated glass and plastic manufacturer. 

A specialist in chromatography, biotechnology and environmental products which include glass and plastic vials, closures and accessories, the  patented 96-Well Multi-Tier™ Micro Plate System and accessories, VOA/EPA vials, and sampling bottles and jars – pre-cleaned and pre-cleaned/certified.  Their manufacturing operations located in Vineland, NJ, USA, combine the most modern and highly automated equipment with our own custom designed machinery to handle volume production while maintaining product integrity and the highest quality products in the industry.

ACE SuperC18 and SuperPhenylHexyl UHPLC/HPLC columns offer excellent stability across an extended pH range, allowing chromatographers to routinely exploit beneficial selectivity changes at low, intermediate and high pH.

These columns are designed for use with LC/MS compatible buffers and offer ultra-low bleed for improved LC/MS compatibility. They can be used with MeOH and MeCN mobile phases and offer rapid column equilibration without memory effects. ACE SuperC18 columns offer excellent stability up to pH 11.0/11.5 and ACE SuperPhenylHexyl columns offer excellent stability up to pH 11.0.

Thermo Fisher Scientific has developed a new ion chromatography (IC)-based method that overcomes typical challenges associated with quantification of low amounts of ammonia in the presence of a high concentration of sodium in sodium bicarbonate.

Application Note 1073: Determination of Ammonia in Sodium Bicarbonatedemonstrates that this assay meets the analytical performance characteristics recommended by United States Pharmacopeia (USP) General Chapter <1225>, including precisions (retention time relative standard deviation [RSD] less than 0.1% and peak area RSD less than 2%), accuracy (average recovery 88–117%), limits of detection, and robustness...

The Program Committee is pleased to announce the call for papers for the Pittcon 2015 Technical Program.  

Abstracts are currently being accepted for contributed oral and poster presentations in areas such as, but not limited to, analytical chemistry, applied spectroscopy, life science, bioanalysis, food science, nanotechnology, environmental science and pharmaceutical. The 2015 committee is especially interested in topics relevant to energy and fuels. Program Chairman Hub MacDonald commented, “Since this year’s conference will be in New Orleans with Louisiana holding the...

Wyatt Technology Corporation, the world leader in absolute macromolecular characterization instrumentation has published the results of a new study outlining the simultaneous measurement of protein charge and diffusion interaction parameter (k_D) to determine the colloidal stability of two formulations with different long-term stability behavior.

Traditionally, these two properties are measured independently in laborious experiments requiring manual sample preparation and loading. The Möbius^® from Wyatt Technology uses massively-parallel phase-analysis light scattering (MP-PALS) in conjunction with an autosampler to automate this combined measurement. The Möbius is therefore an ideal tool for protein characterization and is unique in its ability to provide a complete picture of...

Kinesis is pleased to announce that it has been appointed the exclusive distributor for the Rapid Extraction System (RES) developed and manufactured by CambTEK Limited.

Under this agreement Kinesis will be responsible for sales and service of the RES throughout the UK and Ireland. The RES was developed by CambTEK to address the long-standing issues of poor productivity and quality of data of solid dose testing, within the pharmaceutical and food industries. The RES is built on a scientific understanding of dissolution and liquid flow as opposed to the traditional invasive homogenization and automation of human processes...

Thermo Fisher Scientific has developed an on-line solid-phase extraction–high-performance liquid chromatography (SPE-HPLC) method combined with ultraviolet (UV) absorbance detection for the simple and sensitive determination of tigecycline in a cell lysate sample.

Application Note 1074:Determination of Tigecycline in a Cell Lysate demonstrates that this approach, performed on a rapid separation LC (RSLC) system controlled by data management software, detects trace amounts of tigecycline in tigecycline-treated cells, concentrations so low that they cannot be assayed using a routine HPLC-UV detection method. The prevalence of multidrug-resistant bacteria in hospitals underscores the need for...

Markes International’s Select-eV variable-energy ion-source technology has received an Honourable Mention at the Pittcon Editors’ Awards, following its introduction earlier this year.

Pittcon, The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, is widely regarded as one of the world’s best trade shows for innovations in analytical chemistry. It gives attendees the opportunity to observe many analytical instrument developments, all under one roof. This year, the conference attracted 16,200 attendees, including 935 exhibitors from 32 countries across 1,763 booths....