Thermo Fisher Scientific has developed an efficient high-performance liquid chromatography method that uses fluorescence detection to achieve a rapid and sensitive determination of rhodamine B in cosmetics.

Application Note 1102: Rapid and Sensitive Determination of Rhodamine B in Cosmetics demonstrates the advantages of this method using a rapid separation liquid chromatography (RSLC) column on an RSLC system. This approach provides good method reproducibility (retention time reproducibility relative standard deviation [RSD] of 0.09% and peak area reproducibility RSD of 0.75%) and a wide linear calibration range (from 2 to 1000 μg/L)...

The Spectroline^® CC-80 and CC-81 ultraviolet viewing systems provide unequaled fluorescence analysis of research findings.

The CC-80 and CC-81 are ideal for use in chromatography, electrophoresis, genetic research, photoresist coating inspection, forensic science and much more. Researchers can custom design their own fluorescence analysis systems by choosing from a wide range of Spectroline UV lamps that are available in 254, 312 and 365nm wavelengths. For even higher UV intensity and greater fluorescent contrast, users can select from 29 Spectroline UV transilluminators...

The Right Honourable George Osborne MP joins Waters CEO Doug Berthiaume to mark the official opening of the Waters Mass Spectrometry Headquarters in Wilmslow

Waters Corporation (NYSE: WAT) celebrated the official opening of its new, custom-built mass spectrometry headquarters in Wilmslow, UK, confirming the company's commitment to innovation and the expanded usage of mass spectrometry. The facility has been designed and equipped to accelerate innovation in the field of mass spectrometry – a sophisticated analytical laboratory technology that is entrenched in our everyday lives....

Laboratories performing environmental analysis, forensics testing or other single quadrupole gas chromatography-mass spectrometry (GC-MS) analyses that need a simple, cost-effective way to add GC-MS/MS capabilities, have a new option with the Thermo Scientific TSQ Duo triple quadrupole GC-MS/MS system.

“We designed this instrument specifically for labs needing to maintain their current GC or single quadrupole GC-MS workflows while adding triple quadrupole capabilities with minimal disruption,” said Paul Silcock, marketing manager, GC-MS for Thermo Fisher Scientific. “The TSQ Duo system allows users to run their current methods and then easily move over to MS/MS analysis when the time is right for them, on a familiar system using the...

MicroSolv’s “Centre Draining Maximum Recovery” (CDMR) vial and bottle design allows liquid samples to flow freely and completely to the bottom of the glass vial or bottle into a conical or concave reservoir. This is especially useful if maximum recovery of a sample is required.

The patented CDMR vial manufacturing process and design results in an internal glass surface that is virtually seamless, eliminating the “internal ridge” that may result in some vial designs when the vial blank is fused to the vial bottom. This “internal ridge” can retain up to 17ul of fluid sample in a 1.8ml vial....

Thermo Fisher Scientific has developed a precise, automated gas chromatography (GC) method for static headspace analysis of residual solvents in flexible packaging, using a headspace autosampler capable of multiple headspace extraction (MHE).

Application Note 10396: Static Headspace Analysis of Residual Solvents in Flexible Packaging and Quantitation with Multiple Headspace Extraction Following EN 13628-1: 2002 demonstrates the combined analytical power of the Thermo Scientific TRACE 1310 GC and the Thermo Scientific TriPlus 300 Headspace Autosampler to detect and quantify solvents that may leach from adhesives in flexible plastic packaging into the food products the packaging was...

Identifies 256 types of glycolipids with LCMS-IT-TOF / Precise analysis of entire glycolipid structure / Supports high precision analysis in various fields 

Shimadzu, one of the world leaders in analytical instrumentation, has released the industry-first glycolipid-specific library, containing information on 256 types of glycolipids. The library is a result of joint research with Dr. Akemi Suzuki, Director of the Institute of Glycoscience at Tokai University, Japan. Even users without specialized expertise can now prepare samples, specify analytical conditions, analyze data and identify glycolipids using an LCMS-IT-TOF liquid chromatograph mass spectrometer....

With clinical laboratories increasingly turning to high throughput LC-MSMS analysis, laboratory automation specialist Tecan and RECIPE Chemicals and Instruments GmbH, a leading manufacturer of IVD/CE diagnostic products, have announced a co-marketing agreement for automation of LC-MSMS IVD kits.

Visitors to Booth #1 at MSACL 2014 EU in Salzburg, Austria, from the 2^nd to the 5^th of September, had the opportunity to discover how Tecan’s flexible Freedom EVO^® platform offers walkaway automation of the RECIPE ClinMass^® LC-MSMS Complete Kits* for the analysis of vitamin D₂/D₃ and immunosuppressants. The automated process has the advantage of eliminating the potential for manual handling errors and increasing the speed of sample preparation three-fold compared to manual protocols, significantly improving turnaround times while enhancing reproducibility, traceability and sample security....

Porvair Sciences has announced a complete storage solution for HPLC fractions comprising its 2ml round deep well microplate and high integrity cap mat seals.

The revolutionary design of the 2ml deep well plate, which for the first time provides scientists with a genuine 2ml working volume in a 45mm height plate, is now coupled with a choice of specially designed cap mats. These flexible, re-usable cap mats prevent evaporation and allow transport and storage of samples in the 2ml plate without the need for expensive heat seals or leaky adhesive-based seals. To ensure complete confidence in the integrity of your sealed HPLC autosampler or...

Thermo Fisher Scientific has developed an efficient ion chromatography (IC) method with on-line sample cleanup for the rapid and sensitive determination of p-toluenesulfonic acid in water-insoluble drugs.

The on-line cleanup step provides the benefits of efficient matrix elimination, time savings, and convenience. Application Brief 165:Determination of p-Toluenesulfonic Acid in Water-Insoluble Drugs shows that this approach—performed on an integrated IC system that includes sample preparation capability and uses an ion chromatography column designed for separation with sodium carbonate/sodium biocarbonate eluents—demonstrates good linearity with a...

The MultiSUB™ range of horizontal gel electrophoresis units from Cleaver Scientific includes a comprehensive choice of optimised units for low- and high-throughput DNA and RNA applications.

MultiSUB™ horizontal gel electrophoresis units have been designed by scientists for scientists. With its advanced features, each unit provides an easy to use, versatile and flexible system that can evolve and adapt with the changing needs of today’s laboratory researcher. All five units in the Cleaver MultiSUB™ gel electrophoresis range deliver an unsurpassed combination of economy of gel and buffer volume, with gel size and...

KNF Lab’s revolutionary new RC900 Rotary Evaporator has achieved outstanding recognition in the renowned Red Dot Design Awards.

The Red Dot Awards, an international competition for design concepts and prototypes, acknowledges the system’s advanced design and user-oriented features. Launched at Analytica in April this year, the RC900 Rotary Evaporator is an efficient, robust instrument set to transform rotary evaporation, making the technique easier and safer than ever before. Its elegant, easy-to-clean design offers a range of novel features focused on simple, reliable operation and...

European laboratories testing feed and food for dioxins and dioxin-like substances now have lower-cost, smaller-footprint alternatives to high-resolution mass spectrometers (HRMS) for confirming levels of the toxic contaminants, thanks to a new  European Union regulation.

Thermo Fisher Scientific worked closely with national reference labs (NRLs) in the European Union to support the development of the new regulation, known as Commission Regulation (EU) No. 709/2014, which permits use of gas chromatograph-triple stage quadrupole mass spectrometers (GC-MS/MS) for confirmation. EU regulations previously permitted the use of GC-MS/MS only to screen samples for dioxins, a group of persistent organic chemicals that can cause...

Thermo Fisher Scientific has developed a high-resolution hydrophobic interaction chromatography (HIC) method that can separate a fusion protein from a truncated version and a structural isomer.

Application Brief 171: High-Resolution Separation of a Fusion Protein demonstrates that two different HIC columns—the Thermo Scientific^™ ProPac^™ HIC-10 column and the new MAbPac^™ HIC-10 column—can each perform this challenging separation. While the ProPac HIC-10 column is an established column for the analysis of monoclonal antibody post-translational modifications, the MAbPac^™ HIC-10 column exhibits the best performance....

Benefits of integrated formulation preparation and analytics for the development of biotherapeutics to be demonstrated in webinar sponsored by Freeslate

Wyatt Technology Corporation, the world leader in instrumentation for characterization of macromolecules and nanoparticles, is pleased to announce co-presentation of a webinar in partnership with Freeslate. Covering the “Application of Automation for Biologics Formulation Preparation and Stability Studies” and sponsored by Freeslate, the leading provider of high throughput research solutions for biopharmaceutical development, the webinar will take place on...

The EZ-2 ENVI from Genevac is designed for gentle evaporation of volatile environmental samples, such as pesticides, and is proven to give excellent recovery and reproducibility.

The system is fully automated, can concentrate a number of samples at the same time and provides protection from cross contamination and bumping. Over the last 25 years, to safeguard sample integrity during rapid and safe evaporation, Genevac has pioneered the development of a range of innovations including SampleGuard temperature control, the Dri-Pure anti-bumping system and most recently the unique SampleGenie technology. The ingenious patented design of...

Thermo Fisher Scientific has developed two rapid and robust high-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) methods for the accurate determination of common sugars in acid-hydrolyzed wood samples.

Application Note (AN) 1089: Determination of Carbohydrates in Acid Hydrolysates of Wood demonstrates that this approach achieves high-resolution separation of even the sugar pair rhamnose-galactose that has been challenging to resolve using existing HPAE-PAD methods. Both methods use a new polymeric column, the Thermo Scientific^™ Dionex^™ CarboPac^™ SA10-4μm column, configured with a new system, the...

Thermo Fisher Scientific has updated an ion chromatography (IC) method to more easily determine total choline (free and bound forms) in 17 samples representing all forms of infant formula, adult nutritionals, and pediatric formulas (powder, ready-to-feed products, and liquid concentrates).

Application Update (AU) 193: Choline in Infant Formula and Adult Nutritionals, a Single Laboratory Validation demonstrates that this simple yet robust approach decreases sample preparation time while accurately determining choline in these products. The method detailed in AU 193 runs on an IC system that requires only a source of degassed DI water for generation of high-purity eluent, thus simplifying operation while increasing precision and...

Built-in shock absorbers and a conical design assure improved precision and reliable performance for automated sample handling systems

MicroSolv’s Reduced Surface Activity (RSA) or low adsorbing autosampler vials are specially formulated and processed to yield a surface that exhibits extremely low levels of adsorption of basic, polar compounds and shows exceptional consistency of adsorption levels from vial to vial.

Many laboratories analyzing monoclonal antibodies (mAb) regularly encounter situations where they need alternative hydrophobic interaction chromatography (HIC) selectivity. Thermo Fisher Scientific has developed new column chemistry that separates many more of these challenging mAbs, antibody-drug conjugates (ADCs) and proteins.

Agilent Technologies, Inc. and Shimadzu Corp. has announced the release of GC instrument control for their respective Chromatography Data Systems (CDS). This provides customers in analytical laboratories with more freedom of choice when selecting a chromatography data system.