Every LC lab has a cache of C18s, but every C18 is not created equal. Because the chemistry tends to be similar, the silica support that carries this ubiquitous octadecylsilane phase becomes vitally important. When you need a general-purpose LC column, don’t just grab any C18. Choose the speed, efficiency, and long-lasting ruggedness of the new Raptor™ C18 SPP LC column....
Thermo Fisher Scientific has developed a method that uses solid-phase extraction (SPE) well plates to improve sample preconcentration prior to analysis while maintaining high levels of precision, accuracy, recovery, and sample cleanliness.
Application Note 20941: SOLAμ for Pre-Analysis Sample Concentration demonstrates the ability to decrease the lower limit of quantitation by a factor of 20 without the need for lengthy evaporation procedures that may compromise analytical results. By performing a preconcentration step during sample preparation, analysts can reduce workflow, provide stability for analytes susceptible to loss or degradation during evaporation/reconstitution, and...
SP Scientific has entered into an exclusive agreement with Physical Sciences Inc. (PSI) to distribute the LyoFlux® 200 Water Vapor Mass Flow Rate Monitor for laboratory and pilot scale freeze dryers.
The LyoFlux® 200 is an innovative two line-of-sight tuneable diode laser absorption spectroscopy (TDLAS) based device for continuous monitoring of laboratory, pilot and production scale lyophilization cycles. Operating in conjunction with SP Scientific’s LyoStar 3 development freeze dryer the LyoFlux® 200 enables users to better understand instantaneous changes in water vapor mass flow, and thus the sublimation rate for a given product during...
As Mastersizer 3000, the world-leading laser diffraction particle size analyzer, celebrates its 3rd birthday, Malvern Instruments is delivering even smarter particle sizing with the launch of two new additions to the Mastersizer portfolio.
The Development Microlute™ from Porvair Sciences is a Solid Phase Extraction (SPE) microplate which provides a wide assortment of phase chemistries and sorbent loadings in a single plate making it ideally suited for method development.
Offering scientists a choice of up to 12 different phases and sorbent loadings (10 -100mg) in a standard format 96-well plate the Development Microlute™ allows you to simply and rapidly screen for the optimal retention and selectivity required to achieve your sample preparation objectives. By providing a complete SPE methods development solution that does not need to be constructed by the user, the Development Microlute™ delivers...
The miVac Quattro from Genevac is the perfect workhorse sample concentrator for biological laboratories tasked with handling larger numbers of samples.
The miVac Quattro centrifugal vacuum concentrator rapidly removes a wide range of solvents, from volatile organic solvents through to DMF, including water, making it the ideal system for concentrating precious samples in applications including oligonucleotide synthesis, RNA/DNA preparation, peptide preparation, sequencing, molecular biology and ADME / toxicology research. A wide variety of high capacity rotors means that the...
Cleaver Scientific has introduced the innovative new COMPAC-50 High Throughput COMET Assay system.
Developed in collaboration with the Oxidative Stress Group at the University of Leicester (Leicester, UK), the unique design of the COMPAC-50 enables simultaneous electrophoresis of up to 50 COMET Assay slides saving considerable lab space and reducing slide handling time by up to two-thirds when compared to previous standard methods. This would equate to a significant time-saving of up to 90% when handling 50 COMET Assay slides.
Read MoreMalvern explores rheology for protein formulation at 2nd Protein-Protein Interaction ConferenceOct 3, 2014
Malvern Instruments will contribute a scientific poster at the 2014 Protein-Protein Interaction Conference, October 23-24, Boston, MA, USA.
The poster describes new work on rheological approaches to protein stability studies during biologics formulation and will be presented by Matt McGann, Malvern Instruments Life Science Sales and Application Specialist for the Americas. The study of rheology in protein formulation and biotherapeutic development is considered to be a developing and ultimately essential measurement....
Porvair Filtration Group, the filtration and separation specialist is set to add an innovative new material to its already extensive range of materials - BioVyon™ hydrophilic porous plastic.
Porvair is already recognised as a world leader in the manufacture of standard porous plastics specifically designed for filtration, separation, purification, diffusion and fluid transfer within the medical industry. The Wrexham-based R&D lab has extended the range of BioVyon™ materials to include this new hydrophilic material which, like all BioVyon™ materials, exhibits low extractables, uniform pore size and stability for long shelf life....
Thermo Fisher Scientific has developed an efficient high-performance liquid chromatography method that uses fluorescence detection to achieve a rapid and sensitive determination of rhodamine B in cosmetics.
Application Note 1102: Rapid and Sensitive Determination of Rhodamine B in Cosmetics demonstrates the advantages of this method using a rapid separation liquid chromatography (RSLC) column on an RSLC system. This approach provides good method reproducibility (retention time reproducibility relative standard deviation [RSD] of 0.09% and peak area reproducibility RSD of 0.75%) and a wide linear calibration range (from 2 to 1000 μg/L)...
The Spectroline®CC-80 and CC-81 ultraviolet viewing systems provide unequaled fluorescence analysis of research findings.
The CC-80 and CC-81 are ideal for use in chromatography, electrophoresis, genetic research, photoresist coating inspection, forensic science and much more. Researchers can custom design their own fluorescence analysis systems by choosing from a wide range of Spectroline UV lamps that are available in 254, 312 and 365nm wavelengths. For even higher UV intensity and greater fluorescent contrast, users can select from 29 Spectroline UV transilluminators...
The Right Honourable George Osborne MP joins Waters CEO Doug Berthiaume to mark the official opening of the Waters Mass Spectrometry Headquarters in Wilmslow
Waters Corporation (NYSE: WAT) celebrated the official opening of its new, custom-built mass spectrometry headquarters in Wilmslow, UK, confirming the company's commitment to innovation and the expanded usage of mass spectrometry. The facility has been designed and equipped to accelerate innovation in the field of mass spectrometry – a sophisticated analytical laboratory technology that is entrenched in our everyday lives....
Laboratories performing environmental analysis, forensics testing or other single quadrupole gas chromatography-mass spectrometry (GC-MS) analyses that need a simple, cost-effective way to add GC-MS/MS capabilities, have a new option with the Thermo Scientific TSQ Duo triple quadrupole GC-MS/MS system.
“We designed this instrument specifically for labs needing to maintain their current GC or single quadrupole GC-MS workflows while adding triple quadrupole capabilities with minimal disruption,” said Paul Silcock, marketing manager, GC-MS for Thermo Fisher Scientific. “The TSQ Duo system allows users to run their current methods and then easily move over to MS/MS analysis when the time is right for them, on a familiar system using the...
MicroSolv’s “Centre Draining Maximum Recovery” (CDMR) vial and bottle design allows liquid samples to flow freely and completely to the bottom of the glass vial or bottle into a conical or concave reservoir. This is especially useful if maximum recovery of a sample is required.
The patented CDMR vial manufacturing process and design results in an internal glass surface that is virtually seamless, eliminating the “internal ridge” that may result in some vial designs when the vial blank is fused to the vial bottom. This “internal ridge” can retain up to 17ul of fluid sample in a 1.8ml vial....
Thermo Fisher Scientific has developed a precise, automated gas chromatography (GC) method for static headspace analysis of residual solvents in flexible packaging, using a headspace autosampler capable of multiple headspace extraction (MHE).
Application Note 10396: Static Headspace Analysis of Residual Solvents in Flexible Packaging and Quantitation with Multiple Headspace Extraction Following EN 13628-1: 2002 demonstrates the combined analytical power of the Thermo Scientific TRACE 1310 GC and the Thermo Scientific TriPlus 300 Headspace Autosampler to detect and quantify solvents that may leach from adhesives in flexible plastic packaging into the food products the packaging was...
Identifies 256 types of glycolipids with LCMS-IT-TOF / Precise analysis of entire glycolipid structure / Supports high precision analysis in various fields
Shimadzu, one of the world leaders in analytical instrumentation, has released the industry-first glycolipid-specific library, containing information on 256 types of glycolipids. The library is a result of joint research with Dr. Akemi Suzuki, Director of the Institute of Glycoscience at Tokai University, Japan. Even users without specialized expertise can now prepare samples, specify analytical conditions, analyze data and identify glycolipids using an LCMS-IT-TOF liquid chromatograph mass spectrometer....
With clinical laboratories increasingly turning to high throughput LC-MSMS analysis, laboratory automation specialist Tecan and RECIPE Chemicals and Instruments GmbH, a leading manufacturer of IVD/CE diagnostic products, have announced a co-marketing agreement for automation of LC-MSMS IVD kits.
Visitors to Booth #1 at MSACL 2014 EU in Salzburg, Austria, from the 2nd to the 5th of September, had the opportunity to discover how Tecan’s flexible Freedom EVO® platform offers walkaway automation of the RECIPE ClinMass® LC-MSMS Complete Kits* for the analysis of vitamin D2/D3 and immunosuppressants. The automated process has the advantage of eliminating the potential for manual handling errors and increasing the speed of sample preparation three-fold compared to manual protocols, significantly improving turnaround times while enhancing reproducibility, traceability and sample security....
Porvair Sciences has announced a complete storage solution for HPLC fractions comprising its 2ml round deep well microplate and high integrity cap mat seals.
The revolutionary design of the 2ml deep well plate, which for the first time provides scientists with a genuine 2ml working volume in a 45mm height plate, is now coupled with a choice of specially designed cap mats. These flexible, re-usable cap mats prevent evaporation and allow transport and storage of samples in the 2ml plate without the need for expensive heat seals or leaky adhesive-based seals. To ensure complete confidence in the integrity of your sealed HPLC autosampler or...
Thermo Fisher Scientific has developed an efficient ion chromatography (IC) method with on-line sample cleanup for the rapid and sensitive determination of p-toluenesulfonic acid in water-insoluble drugs.
The on-line cleanup step provides the benefits of efficient matrix elimination, time savings, and convenience. Application Brief 165:Determination of p-Toluenesulfonic Acid in Water-Insoluble Drugs shows that this approach—performed on an integrated IC system that includes sample preparation capability and uses an ion chromatography column designed for separation with sodium carbonate/sodium biocarbonate eluents—demonstrates good linearity with a...
The MultiSUB™ range of horizontal gel electrophoresis units from Cleaver Scientific includes a comprehensive choice of optimised units for low- and high-throughput DNA and RNA applications.
MultiSUB™ horizontal gel electrophoresis units have been designed by scientists for scientists. With its advanced features, each unit provides an easy to use, versatile and flexible system that can evolve and adapt with the changing needs of today’s laboratory researcher. All five units in the Cleaver MultiSUB™ gel electrophoresis range deliver an unsurpassed combination of economy of gel and buffer volume, with gel size and...
KNF Lab’s revolutionary new RC900 Rotary Evaporator has achieved outstanding recognition in the renowned Red Dot Design Awards.
The Red Dot Awards, an international competition for design concepts and prototypes, acknowledges the system’s advanced design and user-oriented features. Launched at Analytica in April this year, the RC900 Rotary Evaporator is an efficient, robust instrument set to transform rotary evaporation, making the technique easier and safer than ever before. Its elegant, easy-to-clean design offers a range of novel features focused on simple, reliable operation and...
European laboratories testing feed and food for dioxins and dioxin-like substances now have lower-cost, smaller-footprint alternatives to high-resolution mass spectrometers (HRMS) for confirming levels of the toxic contaminants, thanks to a new European Union regulation.
Thermo Fisher Scientific worked closely with national reference labs (NRLs) in the European Union to support the development of the new regulation, known as Commission Regulation (EU) No. 709/2014, which permits use of gas chromatograph-triple stage quadrupole mass spectrometers (GC-MS/MS) for confirmation. EU regulations previously permitted the use of GC-MS/MS only to screen samples for dioxins, a group of persistent organic chemicals that can cause...
Application Note 20941: SOLAμ for Pre-Analysis Sample Concentration demonstrates the ability to decrease the lower limit of quantitation by a factor of 20 without the need for lengthy evaporation procedures that may compromise analytical results. By performing a preconcentration step during sample preparation, analysts can reduce workflow, provide stability for analytes susceptible to loss or degradation during evaporation/reconstitution, and...
The LyoFlux® 200 is an innovative two line-of-sight tuneable diode laser absorption spectroscopy (TDLAS) based device for continuous monitoring of laboratory, pilot and production scale lyophilization cycles. Operating in conjunction with SP Scientific’s LyoStar 3 development freeze dryer the LyoFlux® 200 enables users to better understand instantaneous changes in water vapor mass flow, and thus the sublimation rate for a given product during...
Offering scientists a choice of up to 12 different phases and sorbent loadings (10 -100mg) in a standard format 96-well plate the Development Microlute™ allows you to simply and rapidly screen for the optimal retention and selectivity required to achieve your sample preparation objectives. By providing a complete SPE methods development solution that does not need to be constructed by the user, the Development Microlute™ delivers...
The miVac Quattro centrifugal vacuum concentrator rapidly removes a wide range of solvents, from volatile organic solvents through to DMF, including water, making it the ideal system for concentrating precious samples in applications including oligonucleotide synthesis, RNA/DNA preparation, peptide preparation, sequencing, molecular biology and ADME / toxicology research. A wide variety of high capacity rotors means that the...
The poster describes new work on rheological approaches to protein stability studies during biologics formulation and will be presented by Matt McGann, Malvern Instruments Life Science Sales and Application Specialist for the Americas. The study of rheology in protein formulation and biotherapeutic development is considered to be a developing and ultimately essential measurement....
Porvair is already recognised as a world leader in the manufacture of standard porous plastics specifically designed for filtration, separation, purification, diffusion and fluid transfer within the medical industry. The Wrexham-based R&D lab has extended the range of BioVyon™ materials to include this new hydrophilic material which, like all BioVyon™ materials, exhibits low extractables, uniform pore size and stability for long shelf life....
The CC-80 and CC-81 are ideal for use in chromatography, electrophoresis, genetic research, photoresist coating inspection, forensic science and much more. Researchers can custom design their own fluorescence analysis systems by choosing from a wide range of Spectroline UV lamps that are available in 254, 312 and 365nm wavelengths. For even higher UV intensity and greater fluorescent contrast, users can select from 29 Spectroline UV transilluminators...
“We designed this instrument specifically for labs needing to maintain their current GC or single quadrupole GC-MS workflows while adding triple quadrupole capabilities with minimal disruption,” said Paul Silcock, marketing manager, GC-MS for Thermo Fisher Scientific. “The TSQ Duo system allows users to run their current methods and then easily move over to MS/MS analysis when the time is right for them, on a familiar system using the...
The patented CDMR vial manufacturing process and design results in an internal glass surface that is virtually seamless, eliminating the “internal ridge” that may result in some vial designs when the vial blank is fused to the vial bottom. This “internal ridge” can retain up to 17ul of fluid sample in a 1.8ml vial....
Shimadzu, one of the world leaders in analytical instrumentation, has released the industry-first glycolipid-specific library, containing information on 256 types of glycolipids. The library is a result of joint research with Dr. Akemi Suzuki, Director of the Institute of Glycoscience at Tokai University, Japan. Even users without specialized expertise can now prepare samples, specify analytical conditions, analyze data and identify glycolipids using an LCMS-IT-TOF liquid chromatograph mass spectrometer....
The revolutionary design of the 2ml deep well plate, which for the first time provides scientists with a genuine 2ml working volume in a 45mm height plate, is now coupled with a choice of specially designed cap mats. These flexible, re-usable cap mats prevent evaporation and allow transport and storage of samples in the 2ml plate without the need for expensive heat seals or leaky adhesive-based seals. To ensure complete confidence in the integrity of your sealed HPLC autosampler or...
MultiSUB™ horizontal gel electrophoresis units have been designed by scientists for scientists. With its advanced features, each unit provides an easy to use, versatile and flexible system that can evolve and adapt with the changing needs of today’s laboratory researcher. All five units in the Cleaver MultiSUB™ gel electrophoresis range deliver an unsurpassed combination of economy of gel and buffer volume, with gel size and...
The Red Dot Awards, an international competition for design concepts and prototypes, acknowledges the system’s advanced design and user-oriented features. Launched at Analytica in April this year, the RC900 Rotary Evaporator is an efficient, robust instrument set to transform rotary evaporation, making the technique easier and safer than ever before. Its elegant, easy-to-clean design offers a range of novel features focused on simple, reliable operation and...
Thermo Fisher Scientific worked closely with national reference labs (NRLs) in the European Union to support the development of the new regulation, known as Commission Regulation (EU) No. 709/2014, which permits use of gas chromatograph-triple stage quadrupole mass spectrometers (GC-MS/MS) for confirmation. EU regulations previously permitted the use of GC-MS/MS only to screen samples for dioxins, a group of persistent organic chemicals that can cause...