Shimadzu, one of the world leaders in analytical instrumentation, has released the new Nexera UC SFE/SFC/MS platform combining quick and easy on-line sample extraction with state-of-the-art chromatographic separation and high sensitivity detection.
For the first time ever, it showcases complete automation of SFE sample pre-treatment and analysis by liquid or supercritical fluid chromatography. The Nexera UC system is designed to fulfil the measurement requirements of a wide range of applications including: monitoring of pesticides in food products; investigation of biomarkers; additives in polymers; drug discovery in pharmaceuticals and biopharmaceuticals, environmental controls and cleaning validation, to name just a few.
Read More25% Discount on all SGE GC Capillary Columns!Apr 22, 2015
Kinesis are pleased to offer you a 25% discount on the entire range of SGE GC capillary columns.
We have highlighted a few commonly used phases and some of the popular unique phases from our comprehensive range, but remember that this fantastic offer is valid for all GC capillary columns from SGE! BP5MS - Optimised Silphenylene content for general purpose MS analyses. BP5For general purpose analyses.BPX5 - Extremely inert, suitable for general purpose analyses. Ideal for trace analysis.HT5 - Unique phase for high temperature...
New from WHEATON - MicroLiter Plate Sampling System™
When it comes to high-throughput chromatography, MicroLiter provides the right solution for your work flow. The patented MicroLiter Plate Sampling System™ combines the right microplates, glass inserts, μLmat™ and /or caps with chromatography-based septa to provide secure vessels for even the most volatile of samples...
Read MoreHALO Glycan LC Columns for Oligosaccharides, Including Protein-Linked Glycans and GlycopeptidesApr 22, 2015
Advanced Materials Technology have introduced a new column line in the HALO BioClass family – HALO Glycan columns.
The HALO Glycan stationary phase has a highly polar ligand containing 5 hydroxyl groups, which is attached to the 2.7micron Fused-Core silica particle via novel proprietary linkage chemistry. The Fused-Core particle used for HALO Glycan has a surface area of ~135 m2/g and an average pore size of 90Å. This high performance material provides a column that is specifically targeted for separations of highly polar oligosaccharides and...
Porvair Sciences glass vial storage plate combines 96 borosilicate glass vials of 700µl into a rigid polypropylene carrier microplate to provide a superior product for storage and transportation applications.
This extremely hard wearing plate provides a zero-leachates solution for UHPLC and also for storage scenarios such as combinatorial chemistry where broad chemical resistance and thermal stability is vital. Porvair glass vial storage plates are less costly than solid glass plates and are precisely manufactured to comply with ANSI/SLAS dimensions to ensure complete compatibility with automated equipment. To prevent evaporation...
Genevac reports on how their Rocket Synergy automated evaporator systems are replacing rotary evaporators as the tool of choice for rapid and sample-safe evaporation of natural product extracts.
Working with natural products to derive potential pharmaceutical drug candidates or to identify new flavours and fragrances has a reputation of being very difficult. Sample collection, preparation, extraction, and drying are extremely labour intensive and not easily reproducible from a process standpoint. The traditional bottleneck in the natural product pipeline has been the drying of solvent extracted samples. Historically natural product researchers have used rotary...
Flow Sciences Process Enclosures are designed and customized to protect the process equipment and the personnel.
The EVP Series provides safety from chemical vapors generated during processes such as flash chromatography, evaporation from rotary evaporators, and other process equipment applications. The Process Enclosure Series was developed for vapors to be removed from the application and the lab. Vapors are pulled to the rear of the enclosure, then up through plenums to keep laminar flow across the work surface and remove vapors effectively. For ease of loading and unloading...
Biomolecule Purifications and Analytics Using CIM Monoliths
Hichrom Limited are pleased to announce that they have been appointed as UK distributor for BIA Separations, the leading developer and manufacturer of CIM® (Convective Interaction Media) monolithic chromatographic columns for production, purification and analytics of large biomolecules. BIA Separations is headquartered in Austria, with sales offices in the US and China. Their mission is to develop and produce CIM monolithic columns of highest quality and provide superior research and method development services for the purification and analytics of biomolecules....
The ground-breaking sensitivity of Malvern Instruments’ new OMNISEC gel permeation chromatography/size exclusion chromatography system generated significant excitement from scientists meeting at the Seventh International Symposium on the Separation and Characterization of Natural and Synthetic Macromolecules (SCM-7), when the system made a well-received debut late in January.
“Delegates were particularly enthusiastic about OMNISEC’s sensitivity,” said Paul Clarke, Industrial Portfolio Manager at Malvern Instruments. “Announcing ‘the most sensitive light scattering detector on the market’ is one thing but seeing what that actually means in practice is another. Demonstrations of the system measuring the molecular weight (MW) of a 100,000 Da Polystyrene standard with just a 100 ng of sample made a big impression and...
EcoPure brand caps for chromatography vials offer an economical, very clean, contaminate-free closure designed to fit most 12 x 32mm (2ml) HPLC and GC vials.
Their proprietary one piece polymer blend and unique sealing cone assures the lightest puncture force and best sealing system for a low cost, single piece cap. Since there is no split septa, the caps can be used for either analysis or for long term storage with no evaporative loss. No septa means no failed samples due to septa dislodging into vial. And no silicone means no worries about potential unidentifiable peaks from silicone layer contaminants, especially using LC/MS.
Read MoreHow to Minimize HPLC Pump System ProblemsMar 19, 2015
High performance liquid chromatography requires extremely accurate pumping systems delivering an accurate, precise and pulse-free flow of the mobile phase.
An HPLC pump system is a complex device with multiple moving parts subject to wear. Standard operating procedures should be in place to both minimize wear such as caused by particulate matter settling in valves and other components, and having spares on hand to replace components subject to wear (i.e. valves, piston and piston seal components). As one of many maintenance steps it is always a good idea to flush your HPLC system with rinse solvents after analysis with...
The PREP Symposium strives to provide the participants with a stage to present and discuss the very latest scientific and technological advances in preparative and process chromatography, with an exposure to the latest chromatography products available on the market, and with opportunities for training and continuing education.
Researchers with new results in areas relevant to the meeting topics are encouraged to submit abstracts online. We are striving to ensure the broadest possible coverage and exchange of recent advances. Please go to the link to "Key Dates" and "Topics" to see abstract submission deadlines. The meeting will include: A Strong Applications-Oriented Workshop Program, A Vendor Exhibit Providing Access to the Latest Advances on...
The VS20 WAVE from Cleaver Scientific is a single tank electrophoresis system which provides a fully integrated solution for vertical PAGE, tube gel IEF and electro blotting.
Interchangeable modular inserts on the innovative VS20 WAVE allow users to combine vertical PAGE with capillary gel IEF to perform 2D electrophoresis, followed by Western transfer for enhanced sensitivity. In addition to unmatched operational versatility the VS20 WAVE also offers ultra-fast set-up. Proprietary vertical screw-clamp technology reduces the number of screws required for set up compared to traditional electrophoresis systems, thereby dramatically reducing assembly time. The ergonomic design of the VS20 WAVE aids both handling and set-up, while its built-in inner buffer chamber allows set-up to be completed without the inclusion of a top tank or upper buffer chamber....
Read MoreCheminert High Pressure Fittings for 360 Mar 16, 2015
VICI Valco’s Cheminert High Pressure PEEK?Fittings are rated at 5000 psi with fingertight nuts, well beyond the burst strength of most PEEK tubing.
The taper angle and detail design conform to the industry standard established by the Valco line. The Cheminert UHPLC Fitting designs permit direct connection of 360 micron OD fused silica, PEEK, stainless, or electroformed nickel tubing without having to use troublesome liners. Because of the fitting’s compact size and fine 2-56 threads, a leak-free connection that seals at pressures well in excess of 20,000 psi can be easily formed with...
At the European Winter Conference on Plasma Spectrochemistry in Münster the Company launches two new mass spectrometers for its global sales
Analytik Jena AG expands its product range: only half a year after the acquisition of the ICP-MS business of the Bruker Corporation in September 2014, Analytik Jena introduces two new ICP-MS products (inductively coupled plasma for use in mass spectronomy) PlasmaQuant ® MS and PlasmaQuant ® MS Elite.The instruments will be unveiled at the European Winter Conference on Plasma Spectrochemistry (EWCPS)...
Genevac has launched a web page that brings together the latest technological innovations and application advances, with links to reference papers, detailing how new fast, safe evaporative sample preparation techniques are benefiting metabolism and toxicology studies.
Visitors to the new web page can gain an insight into how Genevac evaporators are providing fast, safe sample preparation, free from artefact, contamination or loss, from simple concentration or drying of solvent extracts from tissue samples right through to quantitative screening of workers or athletes for the presence of a drug...
Magritek, a leading provider of compact NMR and MRI instruments, report on the use of their Spinsolve Benchtop NMR spectrometer for reaction monitoring studies in the Cronin Group in the Chemistry Department of the University of Glasgow.
Professor Lee Cronin holds the Regius Chair of Chemistry at the University of Glasgow. Research in the Cronin Group is motivated by the fascination for complex chemical systems and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks. They are developing a new approach to the chemical sciences which they call Chemical Cybernetics. This combines...
A new whitepaper from Malvern Instruments provides detailed guidance on the analytical technologies that help to accelerate oral solid dosage (OSD) product formulation to a successful conclusion.
‘Analytical techniques with a place in the oral solid dosage formulation toolkit’ reviews the regulatory and QbD framework associated with OSD formulation and demonstrates how Malvern systems can be used to generate the data required. The goal of formulation is to incorporate an identified drug substance into a successful pharmaceutical product. The regulatory framework for OSD products highlights the need to comprehensively...
Flame brings flexible sensing power to research and teaching labs
Ocean Optics has launched a spectrometer line that combines decades of miniature spectrometer design expertise with industry-leading manufacturing techniques. The Flame spectrometer delivers high thermal stability and low unit to unit variation without compromising the flexibility and configurability that are the hallmark of modular, miniature spectrometers. Features such as interchangeable slits, indicator LEDs and simpler device...
Taking pictures with your camera you may find that images often look okay on a first glimpse, but when zooming in fine details are barely noticeable.
In contrast, the high information density of high resolution images will reveal even the smallest details. Since the introduction of ICP optical emission spectrometry, the spectral resolution has been a main concern with respect to accuracy and sensitivity. The wealth of emission lines from the plasma frequently leads to overlapping between lines of the analyte and that of accompanying elements. In many sample matrices such spectral interferences...
ACE UltraCore SuperC18 has been specifically designed for demanding MS application work and is based on high efficiency, low back pressure solid-core particles with a unique Encapsulated Bonding Technology (EBT).
This technology dramatically increases ligand coverage on the solid-core silica surface and consequently provides a number of key advantages for MS users. Advantage Number 1 for MS Users: Improved Peak Shape and MS Signal Intensity - ACE UltraCore SuperC18 columns have earned a well deserved reputation for delivering highly efficient symmetrical peaks, even with the most challenging of molecules. The use of a highly efficient column exhibiting minimal peak tailing will result in an improved MS signal response.....
Cogent Diol and Cogent UDA (undecanoic acid) are the latest additions to the MicroSolv range of stationary phases for high performance liquid chromatography (HPLC). Both columns are based on MicroSolv’s unique TYPE-C Silica and silica hydride surface chemistry.
Cogent Diol is a 4um diol bonded phase suitable for the reversed-phase or aqueous normal-phase (ANP) analysis of polar compounds and is LC-MS compatible. Columns show fast equilibration between gradient runs and can be successfully used in studies of pathways in human pathology.
We have highlighted a few commonly used phases and some of the popular unique phases from our comprehensive range, but remember that this fantastic offer is valid for all GC capillary columns from SGE! BP5MS - Optimised Silphenylene content for general purpose MS analyses. BP5For general purpose analyses.BPX5 - Extremely inert, suitable for general purpose analyses. Ideal for trace analysis.HT5 - Unique phase for high temperature...
The HALO Glycan stationary phase has a highly polar ligand containing 5 hydroxyl groups, which is attached to the 2.7micron Fused-Core silica particle via novel proprietary linkage chemistry. The Fused-Core particle used for HALO Glycan has a surface area of ~135 m2/g and an average pore size of 90Å. This high performance material provides a column that is specifically targeted for separations of highly polar oligosaccharides and...
This extremely hard wearing plate provides a zero-leachates solution for UHPLC and also for storage scenarios such as combinatorial chemistry where broad chemical resistance and thermal stability is vital. Porvair glass vial storage plates are less costly than solid glass plates and are precisely manufactured to comply with ANSI/SLAS dimensions to ensure complete compatibility with automated equipment. To prevent evaporation...
Working with natural products to derive potential pharmaceutical drug candidates or to identify new flavours and fragrances has a reputation of being very difficult. Sample collection, preparation, extraction, and drying are extremely labour intensive and not easily reproducible from a process standpoint. The traditional bottleneck in the natural product pipeline has been the drying of solvent extracted samples. Historically natural product researchers have used rotary...
The EVP Series provides safety from chemical vapors generated during processes such as flash chromatography, evaporation from rotary evaporators, and other process equipment applications. The Process Enclosure Series was developed for vapors to be removed from the application and the lab. Vapors are pulled to the rear of the enclosure, then up through plenums to keep laminar flow across the work surface and remove vapors effectively. For ease of loading and unloading...
“Delegates were particularly enthusiastic about OMNISEC’s sensitivity,” said Paul Clarke, Industrial Portfolio Manager at Malvern Instruments. “Announcing ‘the most sensitive light scattering detector on the market’ is one thing but seeing what that actually means in practice is another. Demonstrations of the system measuring the molecular weight (MW) of a 100,000 Da Polystyrene standard with just a 100 ng of sample made a big impression and...
Their proprietary one piece polymer blend and unique sealing cone assures the lightest puncture force and best sealing system for a low cost, single piece cap. Since there is no split septa, the caps can be used for either analysis or for long term storage with no evaporative loss. No septa means no failed samples due to septa dislodging into vial. And no silicone means no worries about potential unidentifiable peaks from silicone layer contaminants, especially using LC/MS.
An HPLC pump system is a complex device with multiple moving parts subject to wear. Standard operating procedures should be in place to both minimize wear such as caused by particulate matter settling in valves and other components, and having spares on hand to replace components subject to wear (i.e. valves, piston and piston seal components). As one of many maintenance steps it is always a good idea to flush your HPLC system with rinse solvents after analysis with...
Researchers with new results in areas relevant to the meeting topics are encouraged to submit abstracts online. We are striving to ensure the broadest possible coverage and exchange of recent advances. Please go to the link to "Key Dates" and "Topics" to see abstract submission deadlines. The meeting will include: A Strong Applications-Oriented Workshop Program, A Vendor Exhibit Providing Access to the Latest Advances on...
The taper angle and detail design conform to the industry standard established by the Valco line. The Cheminert UHPLC Fitting designs permit direct connection of 360 micron OD fused silica, PEEK, stainless, or electroformed nickel tubing without having to use troublesome liners. Because of the fitting’s compact size and fine 2-56 threads, a leak-free connection that seals at pressures well in excess of 20,000 psi can be easily formed with...
Analytik Jena AG expands its product range: only half a year after the acquisition of the ICP-MS business of the Bruker Corporation in September 2014, Analytik Jena introduces two new ICP-MS products (inductively coupled plasma for use in mass spectronomy) PlasmaQuant ® MS and PlasmaQuant ® MS Elite.The instruments will be unveiled at the European Winter Conference on Plasma Spectrochemistry (EWCPS)...
Visitors to the new web page can gain an insight into how Genevac evaporators are providing fast, safe sample preparation, free from artefact, contamination or loss, from simple concentration or drying of solvent extracts from tissue samples right through to quantitative screening of workers or athletes for the presence of a drug...
Professor Lee Cronin holds the Regius Chair of Chemistry at the University of Glasgow. Research in the Cronin Group is motivated by the fascination for complex chemical systems and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks. They are developing a new approach to the chemical sciences which they call Chemical Cybernetics. This combines...
‘Analytical techniques with a place in the oral solid dosage formulation toolkit’ reviews the regulatory and QbD framework associated with OSD formulation and demonstrates how Malvern systems can be used to generate the data required. The goal of formulation is to incorporate an identified drug substance into a successful pharmaceutical product. The regulatory framework for OSD products highlights the need to comprehensively...
Ocean Optics has launched a spectrometer line that combines decades of miniature spectrometer design expertise with industry-leading manufacturing techniques. The Flame spectrometer delivers high thermal stability and low unit to unit variation without compromising the flexibility and configurability that are the hallmark of modular, miniature spectrometers. Features such as interchangeable slits, indicator LEDs and simpler device...
In contrast, the high information density of high resolution images will reveal even the smallest details. Since the introduction of ICP optical emission spectrometry, the spectral resolution has been a main concern with respect to accuracy and sensitivity. The wealth of emission lines from the plasma frequently leads to overlapping between lines of the analyte and that of accompanying elements. In many sample matrices such spectral interferences...
This technology dramatically increases ligand coverage on the solid-core silica surface and consequently provides a number of key advantages for MS users. Advantage Number 1 for MS Users: Improved Peak Shape and MS Signal Intensity - ACE UltraCore SuperC18 columns have earned a well deserved reputation for delivering highly efficient symmetrical peaks, even with the most challenging of molecules. The use of a highly efficient column exhibiting minimal peak tailing will result in an improved MS signal response.....
Cogent Diol is a 4um diol bonded phase suitable for the reversed-phase or aqueous normal-phase (ANP) analysis of polar compounds and is LC-MS compatible. Columns show fast equilibration between gradient runs and can be successfully used in studies of pathways in human pathology.