The 'Safe' Series of products from Cleaver Scientific have been designed to make DNA electrophoresis procedures safer, more convenient and more economical to run.
It is widely acknowledged that the main hazards of traditional DNA gel electrophoresis lie in the use of Ethidium Bromide stain, a known mutagen and carcinogen, and using UV illumination sources which can cause eye and skin damage. Furthermore, traditional DNA electrophoresis is usually performed without researchers knowing much about what is happening on the gel unit until it is stopped and checked. This blind 'stop and start’ process, where an...
The unrivalled performance of OMNISEC, Malvern Instruments’ new gel permeation chromatography/size exclusion chromatography (GPC/SEC) system, is demonstrated in a series of recently released application notes which highlight the sensitivity of the system in synthetic polymer analysis.
The OMNISEC platform brings together highly efficient and precise sample separation in the OMNISEC RESOLVE module with a fully integrated, high sensitivity multi-detector array in the OMNISEC REVEAL module. A complete OMNISEC system delivers the accurate molecular weight and molecular size measurements and detailed structural information needed to drive synthetic polymer research. The polymer industry is actively engaged in developing...
Porvair Sciences glass vial storage plate combines 96 borosilicate glass vials of 700µl into a rigid polypropylene carrier microplate to provide a superior product for storage and transportation applications.
This extremely hard wearing plate provides a zero-leachates solution for UHPLC and also for storage scenarios such as combinatorial chemistry where broad chemical resistance and thermal stability is vital. Porvair glass vial storage plates are less costly than solid glass plates and are precisely manufactured to comply with ANSI/SLAS dimensions to ensure complete compatibility with automated equipment. To prevent evaporation or...
Kinesis and Trajan Scientific and Medical (Trajan) are pleased to announce Kinesis as an approved distribution partner for the SGE Analytical Science (SGE) range of Chromatography Consumables in the US.
SGE is a Trajan brand, established in 1960 and integrated into Trajan in 2013. The SGE brand is well known for its diamond syringe quality and is the global market leader in niche areas such as autosampler syringes and GC inlet liners. Trajan’s focus is on developing and commercializing technologies that enable analytical systems to be more selective, sensitive and specific for biological, environmental or food related measurements especially...
The new HALO Glycan HPLC stationary phase is a high performance material specifically targeted for separations of highly polar oligosaccharides, and particularly protein-linked glycans and glycopeptides, by hydrophilic interactive liquid chromatography (HILIC). The phase has a highly polar ligand containing 5 hydroxyl groups, which is attached to a 2.7micron Fused-Core silica particle via novel proprietary linkage chemistry....
visionCATS stands for ease of use and intuitive simplicity.
The new software organizes the workflow of HPTLC and controls all involved CAMAG instruments. The easy-to-navigate user interface guides effectively through the chromatographic process - from analysis definition to analysis reporting. As state-of-the-art software, visionCATS is based on a client-server system offering enormous flexibility to the number of instruments and users that are working together and enabling access to the same data for all members of a work group.
Malvern Instruments will showcase their expanding range of products for the life science and industrial sectors at ACHEMA 2015.
The four-day event (15-19 June) being held in Frankfurt, Germany will be the first major European outing for the latest additions to Malvern’s recently acquired MicroCal microcalorimetry range and for the innovative OMNISEC GPC/SEC platform. Visit the Malvern stand in Hall 4.1, stand number D59. Malvern’s products for life scientists provide information to drive drug discovery and development. Center stage will be the recently...
NMR Honey Profiling: This new NMR screening solution specifically designed for the analysis of honey is the most recent module of Bruker’s well-established FoodScreener product line.
The solution delivers targeted and non-targeted analysis to simultaneously identify and quantify a multitude of honey characteristics, including sugar, acid and amino acid content, as well as detecting frauds such as the addition of different types of syrup or other sugar solutions. The inherent ease of use allows non-expert users to conduct analyses from measurement to final report in minutes and without chromatography. The NMR...
Study published in Nature outlines use of Wyatt’s Calypso II system to confirm the stoichiometry of αSNAP-SNARE complex
Wyatt Technology Corporation, the world leader in instrumentation for absolute macromolecular and nanoparticle characterization, is pleased to highlight a new study that describes the use of composition-gradient multi-angle light scattering (CG-MALS) for the characterization of complex protein-protein interactions. The study, entitled ‘Mechanistic insights into the recycling machine of the SNARE complex’, was published in the...
Shimadzu, one of the world leaders in analytical instrumentation, has released the new Nexera UC SFE/SFC/MS platform combining quick and easy on-line sample extraction with state-of-the-art chromatographic separation and high sensitivity detection.
For the first time ever, it showcases complete automation of SFE sample pre-treatment and analysis by liquid or supercritical fluid chromatography. The Nexera UC system is designed to fulfil the measurement requirements of a wide range of applications including: monitoring of pesticides in food products; investigation of biomarkers; additives in polymers; drug discovery in pharmaceuticals and biopharmaceuticals, environmental controls and cleaning validation, to name just a few.
Read More25% Discount on all SGE GC Capillary Columns!Apr 22, 2015
Kinesis are pleased to offer you a 25% discount on the entire range of SGE GC capillary columns.
We have highlighted a few commonly used phases and some of the popular unique phases from our comprehensive range, but remember that this fantastic offer is valid for all GC capillary columns from SGE! BP5MS - Optimised Silphenylene content for general purpose MS analyses. BP5For general purpose analyses.BPX5 - Extremely inert, suitable for general purpose analyses. Ideal for trace analysis.HT5 - Unique phase for high temperature...
New from WHEATON - MicroLiter Plate Sampling System™
When it comes to high-throughput chromatography, MicroLiter provides the right solution for your work flow. The patented MicroLiter Plate Sampling System™ combines the right microplates, glass inserts, μLmat™ and /or caps with chromatography-based septa to provide secure vessels for even the most volatile of samples...
Read MoreHALO Glycan LC Columns for Oligosaccharides, Including Protein-Linked Glycans and GlycopeptidesApr 22, 2015
Advanced Materials Technology have introduced a new column line in the HALO BioClass family – HALO Glycan columns.
The HALO Glycan stationary phase has a highly polar ligand containing 5 hydroxyl groups, which is attached to the 2.7micron Fused-Core silica particle via novel proprietary linkage chemistry. The Fused-Core particle used for HALO Glycan has a surface area of ~135 m2/g and an average pore size of 90Å. This high performance material provides a column that is specifically targeted for separations of highly polar oligosaccharides and...
Porvair Sciences glass vial storage plate combines 96 borosilicate glass vials of 700µl into a rigid polypropylene carrier microplate to provide a superior product for storage and transportation applications.
This extremely hard wearing plate provides a zero-leachates solution for UHPLC and also for storage scenarios such as combinatorial chemistry where broad chemical resistance and thermal stability is vital. Porvair glass vial storage plates are less costly than solid glass plates and are precisely manufactured to comply with ANSI/SLAS dimensions to ensure complete compatibility with automated equipment. To prevent evaporation...
Genevac reports on how their Rocket Synergy automated evaporator systems are replacing rotary evaporators as the tool of choice for rapid and sample-safe evaporation of natural product extracts.
Working with natural products to derive potential pharmaceutical drug candidates or to identify new flavours and fragrances has a reputation of being very difficult. Sample collection, preparation, extraction, and drying are extremely labour intensive and not easily reproducible from a process standpoint. The traditional bottleneck in the natural product pipeline has been the drying of solvent extracted samples. Historically natural product researchers have used rotary...
Flow Sciences Process Enclosures are designed and customized to protect the process equipment and the personnel.
The EVP Series provides safety from chemical vapors generated during processes such as flash chromatography, evaporation from rotary evaporators, and other process equipment applications. The Process Enclosure Series was developed for vapors to be removed from the application and the lab. Vapors are pulled to the rear of the enclosure, then up through plenums to keep laminar flow across the work surface and remove vapors effectively. For ease of loading and unloading...
Biomolecule Purifications and Analytics Using CIM Monoliths
Hichrom Limited are pleased to announce that they have been appointed as UK distributor for BIA Separations, the leading developer and manufacturer of CIM® (Convective Interaction Media) monolithic chromatographic columns for production, purification and analytics of large biomolecules. BIA Separations is headquartered in Austria, with sales offices in the US and China. Their mission is to develop and produce CIM monolithic columns of highest quality and provide superior research and method development services for the purification and analytics of biomolecules....
The ground-breaking sensitivity of Malvern Instruments’ new OMNISEC gel permeation chromatography/size exclusion chromatography system generated significant excitement from scientists meeting at the Seventh International Symposium on the Separation and Characterization of Natural and Synthetic Macromolecules (SCM-7), when the system made a well-received debut late in January.
“Delegates were particularly enthusiastic about OMNISEC’s sensitivity,” said Paul Clarke, Industrial Portfolio Manager at Malvern Instruments. “Announcing ‘the most sensitive light scattering detector on the market’ is one thing but seeing what that actually means in practice is another. Demonstrations of the system measuring the molecular weight (MW) of a 100,000 Da Polystyrene standard with just a 100 ng of sample made a big impression and...
EcoPure brand caps for chromatography vials offer an economical, very clean, contaminate-free closure designed to fit most 12 x 32mm (2ml) HPLC and GC vials.
Their proprietary one piece polymer blend and unique sealing cone assures the lightest puncture force and best sealing system for a low cost, single piece cap. Since there is no split septa, the caps can be used for either analysis or for long term storage with no evaporative loss. No septa means no failed samples due to septa dislodging into vial. And no silicone means no worries about potential unidentifiable peaks from silicone layer contaminants, especially using LC/MS.
Read MoreHow to Minimize HPLC Pump System ProblemsMar 19, 2015
High performance liquid chromatography requires extremely accurate pumping systems delivering an accurate, precise and pulse-free flow of the mobile phase.
An HPLC pump system is a complex device with multiple moving parts subject to wear. Standard operating procedures should be in place to both minimize wear such as caused by particulate matter settling in valves and other components, and having spares on hand to replace components subject to wear (i.e. valves, piston and piston seal components). As one of many maintenance steps it is always a good idea to flush your HPLC system with rinse solvents after analysis with...
The PREP Symposium strives to provide the participants with a stage to present and discuss the very latest scientific and technological advances in preparative and process chromatography, with an exposure to the latest chromatography products available on the market, and with opportunities for training and continuing education.
Researchers with new results in areas relevant to the meeting topics are encouraged to submit abstracts online. We are striving to ensure the broadest possible coverage and exchange of recent advances. Please go to the link to "Key Dates" and "Topics" to see abstract submission deadlines. The meeting will include: A Strong Applications-Oriented Workshop Program, A Vendor Exhibit Providing Access to the Latest Advances on...
The VS20 WAVE from Cleaver Scientific is a single tank electrophoresis system which provides a fully integrated solution for vertical PAGE, tube gel IEF and electro blotting.
Interchangeable modular inserts on the innovative VS20 WAVE allow users to combine vertical PAGE with capillary gel IEF to perform 2D electrophoresis, followed by Western transfer for enhanced sensitivity. In addition to unmatched operational versatility the VS20 WAVE also offers ultra-fast set-up. Proprietary vertical screw-clamp technology reduces the number of screws required for set up compared to traditional electrophoresis systems, thereby dramatically reducing assembly time. The ergonomic design of the VS20 WAVE aids both handling and set-up, while its built-in inner buffer chamber allows set-up to be completed without the inclusion of a top tank or upper buffer chamber....
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It is widely acknowledged that the main hazards of traditional DNA gel electrophoresis lie in the use of Ethidium Bromide stain, a known mutagen and carcinogen, and using UV illumination sources which can cause eye and skin damage. Furthermore, traditional DNA electrophoresis is usually performed without researchers knowing much about what is happening on the gel unit until it is stopped and checked. This blind 'stop and start’ process, where an...
The OMNISEC platform brings together highly efficient and precise sample separation in the OMNISEC RESOLVE module with a fully integrated, high sensitivity multi-detector array in the OMNISEC REVEAL module. A complete OMNISEC system delivers the accurate molecular weight and molecular size measurements and detailed structural information needed to drive synthetic polymer research. The polymer industry is actively engaged in developing...
This extremely hard wearing plate provides a zero-leachates solution for UHPLC and also for storage scenarios such as combinatorial chemistry where broad chemical resistance and thermal stability is vital. Porvair glass vial storage plates are less costly than solid glass plates and are precisely manufactured to comply with ANSI/SLAS dimensions to ensure complete compatibility with automated equipment. To prevent evaporation or...
SGE is a Trajan brand, established in 1960 and integrated into Trajan in 2013. The SGE brand is well known for its diamond syringe quality and is the global market leader in niche areas such as autosampler syringes and GC inlet liners. Trajan’s focus is on developing and commercializing technologies that enable analytical systems to be more selective, sensitive and specific for biological, environmental or food related measurements especially...
The new HALO Glycan HPLC stationary phase is a high performance material specifically targeted for separations of highly polar oligosaccharides, and particularly protein-linked glycans and glycopeptides, by hydrophilic interactive liquid chromatography (HILIC). The phase has a highly polar ligand containing 5 hydroxyl groups, which is attached to a 2.7micron Fused-Core silica particle via novel proprietary linkage chemistry....
The new software organizes the workflow of HPTLC and controls all involved CAMAG instruments. The easy-to-navigate user interface guides effectively through the chromatographic process - from analysis definition to analysis reporting. As state-of-the-art software, visionCATS is based on a client-server system offering enormous flexibility to the number of instruments and users that are working together and enabling access to the same data for all members of a work group.
The four-day event (15-19 June) being held in Frankfurt, Germany will be the first major European outing for the latest additions to Malvern’s recently acquired MicroCal microcalorimetry range and for the innovative OMNISEC GPC/SEC platform. Visit the Malvern stand in Hall 4.1, stand number D59. Malvern’s products for life scientists provide information to drive drug discovery and development. Center stage will be the recently...
The solution delivers targeted and non-targeted analysis to simultaneously identify and quantify a multitude of honey characteristics, including sugar, acid and amino acid content, as well as detecting frauds such as the addition of different types of syrup or other sugar solutions. The inherent ease of use allows non-expert users to conduct analyses from measurement to final report in minutes and without chromatography. The NMR...
Wyatt Technology Corporation, the world leader in instrumentation for absolute macromolecular and nanoparticle characterization, is pleased to highlight a new study that describes the use of composition-gradient multi-angle light scattering (CG-MALS) for the characterization of complex protein-protein interactions. The study, entitled ‘Mechanistic insights into the recycling machine of the SNARE complex’, was published in the...
The HALO Glycan stationary phase has a highly polar ligand containing 5 hydroxyl groups, which is attached to the 2.7micron Fused-Core silica particle via novel proprietary linkage chemistry. The Fused-Core particle used for HALO Glycan has a surface area of ~135 m2/g and an average pore size of 90Å. This high performance material provides a column that is specifically targeted for separations of highly polar oligosaccharides and...
This extremely hard wearing plate provides a zero-leachates solution for UHPLC and also for storage scenarios such as combinatorial chemistry where broad chemical resistance and thermal stability is vital. Porvair glass vial storage plates are less costly than solid glass plates and are precisely manufactured to comply with ANSI/SLAS dimensions to ensure complete compatibility with automated equipment. To prevent evaporation...
Working with natural products to derive potential pharmaceutical drug candidates or to identify new flavours and fragrances has a reputation of being very difficult. Sample collection, preparation, extraction, and drying are extremely labour intensive and not easily reproducible from a process standpoint. The traditional bottleneck in the natural product pipeline has been the drying of solvent extracted samples. Historically natural product researchers have used rotary...
The EVP Series provides safety from chemical vapors generated during processes such as flash chromatography, evaporation from rotary evaporators, and other process equipment applications. The Process Enclosure Series was developed for vapors to be removed from the application and the lab. Vapors are pulled to the rear of the enclosure, then up through plenums to keep laminar flow across the work surface and remove vapors effectively. For ease of loading and unloading...
“Delegates were particularly enthusiastic about OMNISEC’s sensitivity,” said Paul Clarke, Industrial Portfolio Manager at Malvern Instruments. “Announcing ‘the most sensitive light scattering detector on the market’ is one thing but seeing what that actually means in practice is another. Demonstrations of the system measuring the molecular weight (MW) of a 100,000 Da Polystyrene standard with just a 100 ng of sample made a big impression and...
Their proprietary one piece polymer blend and unique sealing cone assures the lightest puncture force and best sealing system for a low cost, single piece cap. Since there is no split septa, the caps can be used for either analysis or for long term storage with no evaporative loss. No septa means no failed samples due to septa dislodging into vial. And no silicone means no worries about potential unidentifiable peaks from silicone layer contaminants, especially using LC/MS.
An HPLC pump system is a complex device with multiple moving parts subject to wear. Standard operating procedures should be in place to both minimize wear such as caused by particulate matter settling in valves and other components, and having spares on hand to replace components subject to wear (i.e. valves, piston and piston seal components). As one of many maintenance steps it is always a good idea to flush your HPLC system with rinse solvents after analysis with...
Researchers with new results in areas relevant to the meeting topics are encouraged to submit abstracts online. We are striving to ensure the broadest possible coverage and exchange of recent advances. Please go to the link to "Key Dates" and "Topics" to see abstract submission deadlines. The meeting will include: A Strong Applications-Oriented Workshop Program, A Vendor Exhibit Providing Access to the Latest Advances on...