Climate crisis, artificial intelligence, and vaccines top the list of 2019’s most discussed research. From the increasing use of artificial intelligence to the climate emergency facing us all, many of this year’s most polarizing issues feature in the Altmetric Top 100. The annual Altmetric Top 100 highlights research published in 2019 that has generated significant international online attention and discussion...
2019 was an exciting year for science as it marked the 150th birthday of the periodic table of elements and as a result, the year was designated as the International Year of the Periodic Table. From an old invention to modern day discoveries, in this article Radleys take a look at some more recent advances in the field of Chemistry and the highlights of 2019....
PhoreMost has leveraged its proprietary SITESEEKER® drug discovery platform and PROTEINi® libraries to identify a peptide sequence inhibiting a novel protein target which was previously thought to be undruggable, relevant to an oncogenic cellular pathway. Cresset Discovery Services has been contracted under a flexible service agreement to determine how the peptide binds to the target, and to ultimately help find small molecules that have the same effect....
BioMed X has announced the successful completion of their first research collaboration project with AbbVie in the field of tau-mediated neurodegeneration in Alzheimer’s disease. BioMed X received a milestone payment and the results of the project were transferred to AbbVie. The BioMed X team successfully developed research tools to assess disease-associated post-translational modification signatures of the tau protein in the brains and cerebrospinal fluids...
Scientists have tested a new way to protect crops from a widespread and devastating bacterial disease, without using environmentally damaging chemical sprays. An interdisciplinary team at the University of Glasgow have revealed a new method that could protect many important crop species against the common crop bacteria Pseudomonas syringae (Ps). Ps and related bacterial species attack a wide variety of important crops in the UK and worldwide...
Testa Analytical Solutions reports on considerable interest from protein scientists to use Dynamic Light Scattering (DLS) as a tool for screening for the presence of aggregates as it is extremely sensitive to these larger compounds. Applications Lab Manager - Raffaele Carano said "Protein aggregation is a common challenge in the manufacturing of biological products. Protein scientists particularly like DLS because it provides them with a simple, fast and non-destructive test for aggregate detection....
We live in a three-dimensional ever-changing world. Yet in microscopy, our ability to image in 3D and at the speeds required to observe fast living processes remains a challenge. Compared to other light microscopy techniques, fluorescence microscopy can achieve high specificity and contrast, though there are still major limitations in signal-to-noise ratio and phototoxicity.
Deben, a leading provider of in-situ testing stages together with innovative accessories and components for microscopy, reports on the University of Surrey’s efforts to develop the groundwork of new, state of the art ceramic composites that will revolutionise the treatment of oral disease. Dr Tan Sui is a Materials Engineering Lecturer (Assistant Professor) in the Department of Mechanical Engineering Sciences at the University of Surrey, UK...
Intellegens, an artificial intelligence (AI) start-up, and, Optibrium™, leading providers of software and services for drug discovery, have announced joint success in the Open Source Malaria (OSM) global initiative aimed at identifying the best predictive models for antimalarial compounds. Together, the companies developed one of the top models, deploying a cutting-edge deep neural network algorithm [1], Alchemite™, to accurately predict active compounds...
Scientists have detected an exotic tick-borne parasite within sheep in the North of Scotland, according to a new study. The research, by scientists at the University of Glasgow’s School of Veterinary Medicine and Institute of Biodiversity, Animal Health and Comparative Medicine, was published in Emerging Infectious Diseases, the journal of the Centre for Disease Control (CDC). The study reports that this is the first time this organism, called Babesia venatorum (B. venatorum), has been identified in animals in the UK...
Postnova Analytics has posted a new on-demand webinar introducing how advanced analytical techniques are impacting the field of nanogeochemistry. The webinar discusses the advanced analytical approaches that are used to apply Asymmetric Flow Field-Flow Fractionation with online UV-Visible and ICP-MS detectors to nano-geochemical systems in the SWAMP (Soils, Water, Air, Manures, and Plants) laboratory, at the University of Alberta, Canada....
Radleys explores and looks into how automation is making a significant difference to labs, offering a variety of benefits. It is arguable that we are currently in the midst of an automation revolution. Most things are becoming digitised and everywhere you turn, it seems that technology is doing a job once reserved for a human. From the self-service checkout at the supermarket, to the maps app on your smartphone; some things are now so ingrained in our everyday lives....
Scientists have reported an effective and environmentally sustainable way to block the transmission of mosquito-borne dengue virus, in trials carried out in Malaysia. Using a strain of the bacteria Wolbachia, which inhibit mosquitoes from transmitting viruses to humans, researchers at the Universities of Glasgow and Melbourne and the Institute for Medical Research in Malaysia were successfully able to reduce cases of dengue at sites in Kuala Lumpur...
Rapid 3D imaging and in-depth structural analysis opens up quality monitoring and spermatozoa selection for artificial insemination in humans and animals. A key determinant for success in artificial insemination for humans and animals is the quality of the spermatozoa. However, current 2D label-free imaging methods can only detect abnormal spermatozoa with significant morphological changes or incomplete structures and are unable to provide information on their internal structure or composition....
The Glasgow Precision Oncology Laboratory (GPOL) at the University of Glasgow has developed a ground-breaking new cancer test for research and clinical trials that could ultimately change the way cancer medicine is delivered. The Glasgow Cancer Tests are a suite of affordable solid tumour and blood cancer tests, developed specifically to enable patients to benefit from real-world precision medicine-based cancer treatments....
Agilent Technologies, Inc. has announced that the nomination process to submit proposals to receive an Agilent-sponsored LabCentral Golden Ticket is open for interested life sciences and biotech startup companies. LabCentral, based in Cambridge, Massachusetts, is an independent, shared laboratory space designed as a launchpad for high-potential life sciences and biotech startups.
Lab discoveries of single mutations that increase infectiousness have quadrupled since 2015. Far more bacteria are one step away from becoming dangerous than previously thought, say the team managing the world’s only specialist database on the disease-causing genes of microbes. The scientists, led from Rothamsted Research, say there has been a sharp rise in the number of laboratory studies that show how just a single mutation can create highly infectious or ‘hypervirulent’ strains of disease-causing bacteria, fungi and water moulds...
Anima Biotech, based in Tel Aviv, Israel, is using INTEGRA’s VIAFLO 96/384 handheld electronic pipette to study protein translation in the drive to tackle undruggable targets in diseases such as fibrosis, respiratory syncytial virus, oncology and Huntington's disease. The VIAFLO 96/384’s ability to simultaneously transfer liquids into every well of a multi-well plate has increased the speed of pipetting, improved throughput and enhanced the accuracy of the process....
INTEGRA Biosciences is dedicated to developing innovative solutions to improve ergonomic pipetting in the lab, helping you to avoid repetitive strain injuries (RSIs). Prolonged manual pipetting is an occupation that puts you at risk of developing hand, neck and shoulder injuries, including carpal tunnel syndrome, tendonitis, tenosynovitis, and tennis elbow. INTEGRA supplies a wide range of electronic and manual pipettes suited to various applications....
TTP plc (TTP), a leading independent technology and product development company, has announced that its Desktop Biology™ service has enabled the fast-track development of a novel technology in partnership with DnaNudge Ltd, the developer of the world’s first DNA-based service to “nudge” consumers towards genetically optimal buying behaviour. The technology is designed to help consumers make healthier food and drink choices based on their unique genetic profile...
Hamilton announced that a new Southeast Regional Office joins with its Reno, NV, Franklin, MA, and global locations in providing training programs specific to the software powering their precision liquid handling workstations. The office, located in close proximity to the Research Triangle Park (RTP) area and local airports, opened earlier this year to expand upon Hamilton’s well-known customer service excellence at the local level....
Merck, a leading science and technology company, has announced that it has signed a license agreement providing Evotec SE access to Merck’s foundational CRISPR intellectual property. Evotec, an international biotechnology company headquartered in Hamburg, Germany, will use Merck’s CRISPR genome-editing technology to create edited cell lines for Evotec’s commercial and internal research purposes....
Climate crisis, artificial intelligence, and vaccines top the list of 2019’s most discussed research. From the increasing use of artificial intelligence to the climate emergency facing us all, many of this year’s most polarizing issues feature in the Altmetric Top 100. The annual Altmetric Top 100 highlights research published in 2019 that has generated significant international online attention and discussion...
2019 was an exciting year for science as it marked the 150th birthday of the periodic table of elements and as a result, the year was designated as the International Year of the Periodic Table. From an old invention to modern day discoveries, in this article Radleys take a look at some more recent advances in the field of Chemistry and the highlights of 2019....
PhoreMost has leveraged its proprietary SITESEEKER® drug discovery platform and PROTEINi® libraries to identify a peptide sequence inhibiting a novel protein target which was previously thought to be undruggable, relevant to an oncogenic cellular pathway. Cresset Discovery Services has been contracted under a flexible service agreement to determine how the peptide binds to the target, and to ultimately help find small molecules that have the same effect....
BioMed X has announced the successful completion of their first research collaboration project with AbbVie in the field of tau-mediated neurodegeneration in Alzheimer’s disease. BioMed X received a milestone payment and the results of the project were transferred to AbbVie. The BioMed X team successfully developed research tools to assess disease-associated post-translational modification signatures of the tau protein in the brains and cerebrospinal fluids...
Scientists have tested a new way to protect crops from a widespread and devastating bacterial disease, without using environmentally damaging chemical sprays. An interdisciplinary team at the University of Glasgow have revealed a new method that could protect many important crop species against the common crop bacteria Pseudomonas syringae (Ps). Ps and related bacterial species attack a wide variety of important crops in the UK and worldwide...
Testa Analytical Solutions reports on considerable interest from protein scientists to use Dynamic Light Scattering (DLS) as a tool for screening for the presence of aggregates as it is extremely sensitive to these larger compounds. Applications Lab Manager - Raffaele Carano said "Protein aggregation is a common challenge in the manufacturing of biological products. Protein scientists particularly like DLS because it provides them with a simple, fast and non-destructive test for aggregate detection....
We live in a three-dimensional ever-changing world. Yet in microscopy, our ability to image in 3D and at the speeds required to observe fast living processes remains a challenge. Compared to other light microscopy techniques, fluorescence microscopy can achieve high specificity and contrast, though there are still major limitations in signal-to-noise ratio and phototoxicity.
Deben, a leading provider of in-situ testing stages together with innovative accessories and components for microscopy, reports on the University of Surrey’s efforts to develop the groundwork of new, state of the art ceramic composites that will revolutionise the treatment of oral disease. Dr Tan Sui is a Materials Engineering Lecturer (Assistant Professor) in the Department of Mechanical Engineering Sciences at the University of Surrey, UK...
Intellegens, an artificial intelligence (AI) start-up, and, Optibrium™, leading providers of software and services for drug discovery, have announced joint success in the Open Source Malaria (OSM) global initiative aimed at identifying the best predictive models for antimalarial compounds. Together, the companies developed one of the top models, deploying a cutting-edge deep neural network algorithm [1], Alchemite™, to accurately predict active compounds...
Scientists have detected an exotic tick-borne parasite within sheep in the North of Scotland, according to a new study. The research, by scientists at the University of Glasgow’s School of Veterinary Medicine and Institute of Biodiversity, Animal Health and Comparative Medicine, was published in Emerging Infectious Diseases, the journal of the Centre for Disease Control (CDC). The study reports that this is the first time this organism, called Babesia venatorum (B. venatorum), has been identified in animals in the UK...
Postnova Analytics has posted a new on-demand webinar introducing how advanced analytical techniques are impacting the field of nanogeochemistry. The webinar discusses the advanced analytical approaches that are used to apply Asymmetric Flow Field-Flow Fractionation with online UV-Visible and ICP-MS detectors to nano-geochemical systems in the SWAMP (Soils, Water, Air, Manures, and Plants) laboratory, at the University of Alberta, Canada....
Radleys explores and looks into how automation is making a significant difference to labs, offering a variety of benefits. It is arguable that we are currently in the midst of an automation revolution. Most things are becoming digitised and everywhere you turn, it seems that technology is doing a job once reserved for a human. From the self-service checkout at the supermarket, to the maps app on your smartphone; some things are now so ingrained in our everyday lives....
Scientists have reported an effective and environmentally sustainable way to block the transmission of mosquito-borne dengue virus, in trials carried out in Malaysia. Using a strain of the bacteria Wolbachia, which inhibit mosquitoes from transmitting viruses to humans, researchers at the Universities of Glasgow and Melbourne and the Institute for Medical Research in Malaysia were successfully able to reduce cases of dengue at sites in Kuala Lumpur...
Rapid 3D imaging and in-depth structural analysis opens up quality monitoring and spermatozoa selection for artificial insemination in humans and animals. A key determinant for success in artificial insemination for humans and animals is the quality of the spermatozoa. However, current 2D label-free imaging methods can only detect abnormal spermatozoa with significant morphological changes or incomplete structures and are unable to provide information on their internal structure or composition....
The Glasgow Precision Oncology Laboratory (GPOL) at the University of Glasgow has developed a ground-breaking new cancer test for research and clinical trials that could ultimately change the way cancer medicine is delivered. The Glasgow Cancer Tests are a suite of affordable solid tumour and blood cancer tests, developed specifically to enable patients to benefit from real-world precision medicine-based cancer treatments....
Agilent Technologies, Inc. has announced that the nomination process to submit proposals to receive an Agilent-sponsored LabCentral Golden Ticket is open for interested life sciences and biotech startup companies. LabCentral, based in Cambridge, Massachusetts, is an independent, shared laboratory space designed as a launchpad for high-potential life sciences and biotech startups.
Lab discoveries of single mutations that increase infectiousness have quadrupled since 2015. Far more bacteria are one step away from becoming dangerous than previously thought, say the team managing the world’s only specialist database on the disease-causing genes of microbes. The scientists, led from Rothamsted Research, say there has been a sharp rise in the number of laboratory studies that show how just a single mutation can create highly infectious or ‘hypervirulent’ strains of disease-causing bacteria, fungi and water moulds...
Anima Biotech, based in Tel Aviv, Israel, is using INTEGRA’s VIAFLO 96/384 handheld electronic pipette to study protein translation in the drive to tackle undruggable targets in diseases such as fibrosis, respiratory syncytial virus, oncology and Huntington's disease. The VIAFLO 96/384’s ability to simultaneously transfer liquids into every well of a multi-well plate has increased the speed of pipetting, improved throughput and enhanced the accuracy of the process....
INTEGRA Biosciences is dedicated to developing innovative solutions to improve ergonomic pipetting in the lab, helping you to avoid repetitive strain injuries (RSIs). Prolonged manual pipetting is an occupation that puts you at risk of developing hand, neck and shoulder injuries, including carpal tunnel syndrome, tendonitis, tenosynovitis, and tennis elbow. INTEGRA supplies a wide range of electronic and manual pipettes suited to various applications....
TTP plc (TTP), a leading independent technology and product development company, has announced that its Desktop Biology™ service has enabled the fast-track development of a novel technology in partnership with DnaNudge Ltd, the developer of the world’s first DNA-based service to “nudge” consumers towards genetically optimal buying behaviour. The technology is designed to help consumers make healthier food and drink choices based on their unique genetic profile...
Hamilton announced that a new Southeast Regional Office joins with its Reno, NV, Franklin, MA, and global locations in providing training programs specific to the software powering their precision liquid handling workstations. The office, located in close proximity to the Research Triangle Park (RTP) area and local airports, opened earlier this year to expand upon Hamilton’s well-known customer service excellence at the local level....
Merck, a leading science and technology company, has announced that it has signed a license agreement providing Evotec SE access to Merck’s foundational CRISPR intellectual property. Evotec, an international biotechnology company headquartered in Hamburg, Germany, will use Merck’s CRISPR genome-editing technology to create edited cell lines for Evotec’s commercial and internal research purposes....