More than a century after giving the world aspirin, another potential drug has been found in the stem and leaves of willows – this time with anti-cancer properties. Scientists led from Rothamsted Research, working with cancer biologists at the University of Kent have discovered the chemical, miyabeacin, which has been found to kill various cancer cells, including those resistant to other drugs....
Merck, a leading science and technology company, has announced a second Carlsbad, California, U.S.A.-based facility for its BioReliance® viral and gene therapy service offering. The new, € 100 million commercial facility is expected to open next year. “Viral vector manufacturing has transitioned from a niche industry to the cornerstone of the future of biopharmaceuticals,” said Udit Batra, member of the Merck Executive Board and CEO, Life Science....
A wholistic tumour sampling method that more accurately detects genetic alterations in tumours, which are critical in allowing treatment to be personalised to each and every patient, has been developed by researchers from the Crick, Roche and The Royal Marsden NHS Foundation Trust and published in Cell Reports. To help doctors select treatment options for cancer patients, a sample from their tumour can be DNA sequenced....
Fully inclusive and managed RBDS uses Bioquell’s 35% hydrogen peroxide vapour solution to eliminate pathogens, providing a 6-log sporicidal kill. With the number of COVID-19 cases rising globally, Bioquell, a leading manufacturer of high-performance bio-decontamination systems, is offering a proven solution to help eradicate coronavirus in a range of healthcare, life sciences and pharmaceutical environments, including isolation rooms and public spaces....
Avacta Group plc (AIM: AVCT), the developer of Affimer® biotherapeutics and reagents, is pleased to announce that it has entered into a collaboration with Cytiva, formerly known as GE Healthcare Life Sciences. The companies will develop and manufacture an Affimer-based point-of-care rapid test intended for screening of large populations to diagnose the COVID-19 coronavirus infection. The World Health Organisation recently....
With years of experience in providing quality contract research services, Profacgen has accumulated experience in virtually all aspects of protein development and protein production. Now, scientists have access to Profacgen’s recently released Trimeric Protein Production Service, generating new insights into the assembly and maturation of trimers that will have implications for the design of effective vaccines....
If you have ever tried to measure formaldehyde by GC using an FID, you will have noticed that the response you get is significantly lower than you might have expected. The flame ionization detector (FID) is the most widely used detector in gas chromatography. It is extremely sensitive with a wide linear range for most organic compounds. However, compounds such as oxygenates, ethers, amides and other organic compounds containing heteroatoms (e.g. O, N, S, Cl, Si), generate a lower or sometimes negligible response....
The accurate identification of biomarkers in biological samples – such as volatiles in breath, saliva and urine – has the potential to provide rapid, minimally-invasive disease diagnosis. However, diagnostic compounds are rarely of high abundance in these complex matrices, so a sensitive and comprehensive approach is required to discover the maximum number of compounds in a realistic run time. Attend this free-of-charge webinar...
Scientists from the University of Oxford’s Engineering Science Department and the Oxford Suzhou Centre for Advanced Research (OSCAR) have developed a rapid testing technology for the novel corona virus SARS-CoV-2 (COVID-19). The team, led by Prof Zhanfeng Cui and Prof Wei Huang, have been working to improve test capabilities as the virus spreads internationally.The new test is much faster and does not need a complicated instrument. The research team has developed a new test, based on a technique which is capable of giving results in just half an hour...
Labs working to combat COVID-19 will benefit from this initiative, as CytoSMART aims to reduce the huge workload currently facing researchers on projects vital to controlling the disease. “We aim to do our part to assist researchers in minimizing the time they have to spend in high-contamination labs, by providing them with remote video access to evaluate the status of their cell cultures. The video data is used to remotely monitor the cytopathic effect, this way researchers know when it’s the right time to harvest the virus....
The movements of cell muscles in the form of tiny filaments of proteins have been visualised at unprecedented detail by University of Warwick scientists. In a study published in the Biophysical Journal, scientists from the University’s Department of Physics and Warwick Medical School have used a new microscopy technique to analyse the molecular motors inside cells that allow them to move and reshape themselves, potentially providing new insights that could inform the development of new smart materials....
Kidney involvement seems to be frequent in patients with Covid-19. Proteinuria (and/or blood in urine) often occurs at the beginning or during the infection, a few patients even develop acute kidney injury (AKI). This shows that Covid-19 also attacks the kidneys. Nephrologists from all countries are dedicated and committed to help these patients....
Leica Biosystems, a world-leading cancer diagnostics company, today launches The Future of Pathology Expert Report, now availible for download. The report calls for pathologists and healthcare leaders to collaborate in pursuit of their common goal – to improve cancer diagnostics. Given the uncertain times currently faced by our healthcare communities globally, The Future of Pathology Report details how the field of pathology can evolve....
The likelihood of emerging viruses spreading to humans from animals may not depend on the specific animal reservoir of the original virus. Like the current pandemic caused by the coronavirus SARS-CoV-2, which is thought to have originated in bats, most emerging infectious diseases are zoonotic viruses – diseases that spread from animals to infect humans...
BBI Solutions has been announced as part of a consortium of the UK’s top Diagnostic companies to rapidly develop and rollout millions of coronavirus tests. As part of the government’s National Testing Plan, the expertise and resources of the UK’s world-leading life sciences industries are being pooled to build a large British diagnostics industry as quickly as possible...
The machine, a Tecan Freedom EVO 100, will be used to help automate and accelerate the analysis of samples at the first of the UK Government’s new Lighthouse Labs in Milton Keynes. The state-of-the-art liquid handling machine is designed to automate the pipetting of multiple samples in laboratories undertaking biological testing. The EVO 100 is considerably faster than manual pipetting, increasing the speed at which assays can be run and enhancing sample through-put. The equipment also facilitates better assay reproducibility and allows resources and testing equipment to be used more efficiently....
Researchers at the Cancer Institute, University College London, are using INTEGRA’s unique electronic pipette range to simplify their workflows.Yvette Hoade, a research technician in the Payne Laboratory, Department of Haematology, is investigating mutations associated with various blood diseases such as bone marrow failure and myelodysplastic syndrome (MDS), both age-related disorders that greatly increase the risk of developing leukemia...
Merck, a leading science and technology company, and The Jenner Institute today announced that the Jenner Institute has laid the foundation for large-scale production of its Covid-19 vaccine candidate, ChAdOx1 nCoV-19. With patients enrolled for clinical trials for this vaccine, rapid development of the large-scale manufacturing process is a critical step in quickly and safely delivering it from the lab to patients....
Beaumont Health’s Research Institute is launching America’s largest serological testing study to help answer many questions surrounding the spread of COVID-19 and potentially help treat patients battling the virus. New study aims to determine the total population with COVID-19 antibodies across a health system, identify potential convalescent plasma donors, better understand disease transmission and contribute to a scientifically-based methodology for returning people to work....
ELISAs (enzyme-linked immunosorbent assays) are popular plate-based methods to detect and quantify peptides, proteins, antibodies or hormones. However, they generally involve multiple pipetting steps that are time-consuming and tedious to perform, requiring consistent processing to ensure success. INTEGRA Biosciences offers a range of liquid handling solutions to improve ELISA workflows...
LGC has launched a Proficiency Testing (PT) service for the detection of SARS-CoV-2 (COVID 19) by nucleic acid amplification testing, one of the first global schemes for COVID-19. As increasing numbers of diagnostic methods are made available in the global fight against COVID 19, it is essential that laboratories ensure that their application of methods and subsequent results are reliable and accurate...
Care Access Research, the leader in rapid development and management of high-performing clinical research sites, announced it is leading a validation trial in conjunction with the FDA for a new at-home COVID-19 test developed by a private genomics lab that manufactures DNA screening kits. The goal of this validation study is to evaluate the efficacy of the new at-home test for diagnosing COVID-19....