Phosphoramidites are the essential part in the chemical synthesis of oligonucleotides, short fragments of nucleotides and analogues. During the synthesis, errors can occur which is why the phosphoramidites’ purity needs to be closely monitored. In this application note, it is shown how to analyse phosphoramidites using two different separation modes: reversed phase (RP) and normal phase (NP) chromatography. Due to the complexity of the analytes different interactions can be used in order to achieve acceptable retenetion and resolution...
Since the start of the pandemic, a surge in sampling demand is putting ?laboratories under pressure, driving up the market, especially in labs that do qPCR and PCR applications. Automated liquid handling platforms, like PIPETMAX®, automate most of the liquid handling steps in your assays, increasing throughput and establishing a robust method for your laboratory workflow. Read our article "The benefits of adding robotics to your lab" to discover the major benefits of adopting automated pipetting systems into your liquid handling workflow...
PrecisionLife Limited, a global techbio company using its deep insights into disease biology and patient stratification to drive precision medicine in chronic diseases, is pleased to announce a partnership with Sano Genetics, a genetic research platform enabling patients to participate in ethical research projects, to advance understanding of the long-term effects of coronavirus infection (long COVID)...
Drawing upon decades of chromatographic expertise and knowledge, TESTA Analytical Solution is established as an OEM detector development and supply partner to a growing number of analytical and process instrumentation companies worldwide. A new case study describes how development of novel rapid scanning UV and differential refractive index detectors is helping an industrial and laboratory monitoring solutions provider offer a market leading instrumental solution for monitoring of polymerization reactions....
The biophysics research team at the University of Bayreuth has been taking advantage of the most popular and unrivaled pipette controller, INTEGRA’s PIPETBOY acu 2, for the preparation of buffers, media and samples in its cell culture workflows, simplifying culture set-up, splitting and media exchange. Technical assistant Andrea Hanold explained: “Our main area of research focuses on what influences intracellular transport, internalization processes, and how the cell organizes itself...
Laboratories are fast-paced, efficient work areas that require accurate data and confidence in your equipment, including your sample labels. A lost or damaged label can throw a lab's work into chaos. Losing this invaluable data means unknown variables now exist, such as sample contents, expiration, and impact on any other lab elements. That is why damaged labels will result in destroyed samples and lost work...
Autoscribe Informatics has announced that Covid-19 Test Laboratory, BioGrad Diagnostics, has adopted Matrix Gemini as its Laboratory Information Management System (LIMS). BioGrad manages client and sample data within the LIMS, driving automation and efficiency. BioGrad Diagnostics is a rapidly expanding diagnostics laboratory in the UK focused on fast turn-around COVID-19 samples....
Venomtech is collaborating with Charles River Laboratories, International Inc. to help drug developers explore venom-derived compounds for a wide range of therapeutic targets. This newly formed collaboration will bring together Venomtech’s biology expertise and vast venom-derived peptide library, with Charles River’s drug development and screening knowhow, providing pharmaceutical manufacturers with a one-stop service to explore this unique natural resource.
Merck, a leading science and technology company, today presented Dr. Valérie Gabelica (44), Inserm, and Director of IECB, Pessac, France, with the 2022 Heinrich Emanuel Merck Award for Analytical Science. The award ceremony took place during the analytical conference EuroFAST2022, Nijmegen, the Netherlands, where the prize winner held a lecture entitled “Advancing mass spectrometry to study nucleic acid structures and interactions”.
Can robots adapt their own working methods to solve complex tasks? Researchers at Chalmers University of Technology, Sweden, have developed a new form of AI, which, by observing human behavior, can adapt to perform its tasks in a changeable environment. The hope is that robots which can be flexible in this way will be able to work alongside humans to a much greater degree...
The Froilabo CRP Blast Freezer is designed to rapidly freeze blood plasma in preparation for long term storage in ULT freezers. To preserve the quality and function of fresh frozen plasma (FFP) the freezing process must be rapid and homogeneous. During a Site Acceptance Test (SAT) the Froilabo CRP Blast Freezer was installed on a production line which processed plasma product. In this test, the aim was to verify the final temperature inside the plasma bags was -70°C...
Asynt reports how the implementation of CondenSyn waterless air condensers throughout the teaching labs at the Department of Chemistry at the College of the Sequoias (Visalia, CA) is benefitting the wider community whilst providing outstanding performance for their students. Due to ongoing water shortages, California water officials recently had no alternative but to impose new drought rules throughout the state to discourage wasteful water practices...
Scientists have created a prototype test that can predict which drug combinations are likely to work for cancer patients in as little as 24 to 48 hours. Their cutting-edge technique uses artificial intelligence to analyse large-scale protein data from tumour samples, and is able to predict patients’ response to drugs more accurately than is currently possible...
Metrohm USA is pleased to announce the winner of its 2022 Young Chemist Award, Colby Ott. Colby is a Ph.D. candidate at West Virginia University's Forensic and Investigative Science Department in Morgantown, West Virginia, where his research centers around developing novel methods for screening seized drugs. His work aims to provide reliable and rapid detection in the laboratory and the field, with future applications in forensics, clinical healthcare, and toxicology...
UK genomics company, RevoluGen Ltd welcomes data presented by scientists from its collaborator the Quadram Institute at this years’ Microbiology Society Annual Conference being held in Belfast. The Quadram’s team results demonstrate the advantages of Fire Monkey high molecular weight (HMW) DNA extraction with multiplexed Oxford Nanopore sequencing for cost effective complete hybrid assemblies of pathogen genomes in resolving genomic rearrangements important in acute and chronic Salmonella infections...
The deadly venom of a poisonous sea snail could hold the key to developing new medicines including more effective, less addictive forms of pain relief. A team led by researchers from the University of Glasgow is setting out to learn more about the unique form of venom produced by cone snails, predatory marine animals found in warm seas and oceans throughout the word...
VectorBuilder Inc., a global leader in gene delivery solutions, has announced the construction of a new R&D and manufacturing center in Guangzhou, China. The ‘Gene Delivery Research and Manufacturing Campus’ will significantly expand VectorBuilder’s R&D capabilities and its production capacity for both research-use and cGMP-grade gene delivery vectors, allowing the company to continue supporting groundbreaking research worldwide...
INTEGRA Biosciences’ VOYAGER adjustable tip spacing pipettes and EVOLVE manual pipettes are playing pivotal roles in COVID-19 testing at Children’s Minnesota, an award-winning, non-profit acute pediatric healthcare group in the ‘twin cities’ of Saint Paul and Minneapolis. These innovative tools have helped the group’s molecular laboratory to process more samples, more effectively in this unpredictable sociomedical period....
Autoscribe Informatics, a leading global LIMS provider, is pleased to announce a new case study highlighting the work of the University of Iceland’s forensic toxicology laboratory. The Laboratory of Pharmacology and Toxicology (RLE) configured the Matrix Gemini LIMS themselves, to meet their own unique needs. RLE is now using the LIMS to analyze drug and alcohol samples to support the police and the judiciary in Iceland...
Estación Enológica de Haro (EEH), a public and governmental laboratory situated in the major wine growing region La Rioja, Spain, announces its new wine analysis service for public and private organizations in the oenological sector. The first of its kind to be provided by a laboratory in Spain, the service uses Bruker’s nuclear magnetic resonance (NMR) spectroscopy to identify origin, variety, and authenticity of wine throughout the supply chain...
Deadly and currently undruggable cancer proteins will be the focus of a new research centre dedicated to opening up new approaches to cancer treatment, and made possible by a major philanthropic donation. Scientists at the centre will accelerate research in one of the most promising new areas of drug discovery – targeted protein degradation – to discover new research tools and new treatments for hard-to-treat cancers that can work highly precisely...
Analytik Jena has announced that its annual Science Awards have been awarded for work that employed Analytik Jena solutions in the fields of chemical analysis and molecular biology. Richard Pabst was recognized with the award for “Best Scientific Paper in the Field of Molecular Biology”. In his paper "Modern Species Conservation Using eDNA Analysis”, he explains the potential of PCR analysis in the detection of endangered species in their biotopes....
Phosphoramidites are the essential part in the chemical synthesis of oligonucleotides, short fragments of nucleotides and analogues. During the synthesis, errors can occur which is why the phosphoramidites’ purity needs to be closely monitored. In this application note, it is shown how to analyse phosphoramidites using two different separation modes: reversed phase (RP) and normal phase (NP) chromatography. Due to the complexity of the analytes different interactions can be used in order to achieve acceptable retenetion and resolution...
Since the start of the pandemic, a surge in sampling demand is putting ?laboratories under pressure, driving up the market, especially in labs that do qPCR and PCR applications. Automated liquid handling platforms, like PIPETMAX®, automate most of the liquid handling steps in your assays, increasing throughput and establishing a robust method for your laboratory workflow. Read our article "The benefits of adding robotics to your lab" to discover the major benefits of adopting automated pipetting systems into your liquid handling workflow...
PrecisionLife Limited, a global techbio company using its deep insights into disease biology and patient stratification to drive precision medicine in chronic diseases, is pleased to announce a partnership with Sano Genetics, a genetic research platform enabling patients to participate in ethical research projects, to advance understanding of the long-term effects of coronavirus infection (long COVID)...
Drawing upon decades of chromatographic expertise and knowledge, TESTA Analytical Solution is established as an OEM detector development and supply partner to a growing number of analytical and process instrumentation companies worldwide. A new case study describes how development of novel rapid scanning UV and differential refractive index detectors is helping an industrial and laboratory monitoring solutions provider offer a market leading instrumental solution for monitoring of polymerization reactions....
The biophysics research team at the University of Bayreuth has been taking advantage of the most popular and unrivaled pipette controller, INTEGRA’s PIPETBOY acu 2, for the preparation of buffers, media and samples in its cell culture workflows, simplifying culture set-up, splitting and media exchange. Technical assistant Andrea Hanold explained: “Our main area of research focuses on what influences intracellular transport, internalization processes, and how the cell organizes itself...
Laboratories are fast-paced, efficient work areas that require accurate data and confidence in your equipment, including your sample labels. A lost or damaged label can throw a lab's work into chaos. Losing this invaluable data means unknown variables now exist, such as sample contents, expiration, and impact on any other lab elements. That is why damaged labels will result in destroyed samples and lost work...
Autoscribe Informatics has announced that Covid-19 Test Laboratory, BioGrad Diagnostics, has adopted Matrix Gemini as its Laboratory Information Management System (LIMS). BioGrad manages client and sample data within the LIMS, driving automation and efficiency. BioGrad Diagnostics is a rapidly expanding diagnostics laboratory in the UK focused on fast turn-around COVID-19 samples....
Venomtech is collaborating with Charles River Laboratories, International Inc. to help drug developers explore venom-derived compounds for a wide range of therapeutic targets. This newly formed collaboration will bring together Venomtech’s biology expertise and vast venom-derived peptide library, with Charles River’s drug development and screening knowhow, providing pharmaceutical manufacturers with a one-stop service to explore this unique natural resource.
Merck, a leading science and technology company, today presented Dr. Valérie Gabelica (44), Inserm, and Director of IECB, Pessac, France, with the 2022 Heinrich Emanuel Merck Award for Analytical Science. The award ceremony took place during the analytical conference EuroFAST2022, Nijmegen, the Netherlands, where the prize winner held a lecture entitled “Advancing mass spectrometry to study nucleic acid structures and interactions”.
Can robots adapt their own working methods to solve complex tasks? Researchers at Chalmers University of Technology, Sweden, have developed a new form of AI, which, by observing human behavior, can adapt to perform its tasks in a changeable environment. The hope is that robots which can be flexible in this way will be able to work alongside humans to a much greater degree...
The Froilabo CRP Blast Freezer is designed to rapidly freeze blood plasma in preparation for long term storage in ULT freezers. To preserve the quality and function of fresh frozen plasma (FFP) the freezing process must be rapid and homogeneous. During a Site Acceptance Test (SAT) the Froilabo CRP Blast Freezer was installed on a production line which processed plasma product. In this test, the aim was to verify the final temperature inside the plasma bags was -70°C...
Asynt reports how the implementation of CondenSyn waterless air condensers throughout the teaching labs at the Department of Chemistry at the College of the Sequoias (Visalia, CA) is benefitting the wider community whilst providing outstanding performance for their students. Due to ongoing water shortages, California water officials recently had no alternative but to impose new drought rules throughout the state to discourage wasteful water practices...
Scientists have created a prototype test that can predict which drug combinations are likely to work for cancer patients in as little as 24 to 48 hours. Their cutting-edge technique uses artificial intelligence to analyse large-scale protein data from tumour samples, and is able to predict patients’ response to drugs more accurately than is currently possible...
Metrohm USA is pleased to announce the winner of its 2022 Young Chemist Award, Colby Ott. Colby is a Ph.D. candidate at West Virginia University's Forensic and Investigative Science Department in Morgantown, West Virginia, where his research centers around developing novel methods for screening seized drugs. His work aims to provide reliable and rapid detection in the laboratory and the field, with future applications in forensics, clinical healthcare, and toxicology...
UK genomics company, RevoluGen Ltd welcomes data presented by scientists from its collaborator the Quadram Institute at this years’ Microbiology Society Annual Conference being held in Belfast. The Quadram’s team results demonstrate the advantages of Fire Monkey high molecular weight (HMW) DNA extraction with multiplexed Oxford Nanopore sequencing for cost effective complete hybrid assemblies of pathogen genomes in resolving genomic rearrangements important in acute and chronic Salmonella infections...
The deadly venom of a poisonous sea snail could hold the key to developing new medicines including more effective, less addictive forms of pain relief. A team led by researchers from the University of Glasgow is setting out to learn more about the unique form of venom produced by cone snails, predatory marine animals found in warm seas and oceans throughout the word...
VectorBuilder Inc., a global leader in gene delivery solutions, has announced the construction of a new R&D and manufacturing center in Guangzhou, China. The ‘Gene Delivery Research and Manufacturing Campus’ will significantly expand VectorBuilder’s R&D capabilities and its production capacity for both research-use and cGMP-grade gene delivery vectors, allowing the company to continue supporting groundbreaking research worldwide...
INTEGRA Biosciences’ VOYAGER adjustable tip spacing pipettes and EVOLVE manual pipettes are playing pivotal roles in COVID-19 testing at Children’s Minnesota, an award-winning, non-profit acute pediatric healthcare group in the ‘twin cities’ of Saint Paul and Minneapolis. These innovative tools have helped the group’s molecular laboratory to process more samples, more effectively in this unpredictable sociomedical period....
Autoscribe Informatics, a leading global LIMS provider, is pleased to announce a new case study highlighting the work of the University of Iceland’s forensic toxicology laboratory. The Laboratory of Pharmacology and Toxicology (RLE) configured the Matrix Gemini LIMS themselves, to meet their own unique needs. RLE is now using the LIMS to analyze drug and alcohol samples to support the police and the judiciary in Iceland...
Estación Enológica de Haro (EEH), a public and governmental laboratory situated in the major wine growing region La Rioja, Spain, announces its new wine analysis service for public and private organizations in the oenological sector. The first of its kind to be provided by a laboratory in Spain, the service uses Bruker’s nuclear magnetic resonance (NMR) spectroscopy to identify origin, variety, and authenticity of wine throughout the supply chain...
Deadly and currently undruggable cancer proteins will be the focus of a new research centre dedicated to opening up new approaches to cancer treatment, and made possible by a major philanthropic donation. Scientists at the centre will accelerate research in one of the most promising new areas of drug discovery – targeted protein degradation – to discover new research tools and new treatments for hard-to-treat cancers that can work highly precisely...
Analytik Jena has announced that its annual Science Awards have been awarded for work that employed Analytik Jena solutions in the fields of chemical analysis and molecular biology. Richard Pabst was recognized with the award for “Best Scientific Paper in the Field of Molecular Biology”. In his paper "Modern Species Conservation Using eDNA Analysis”, he explains the potential of PCR analysis in the detection of endangered species in their biotopes....