The PREP Symposium strives to provide the participants with a stage to present and discuss the very latest scientific and technological advances in preparative and process chromatography, with an exposure to the latest chromatography products available on the market, and with opportunities for training and continuing education.
Researchers with new results in areas relevant to the meeting topics are encouraged to submit abstracts online. We are striving to ensure the broadest possible coverage and exchange of recent advances. Please go to the link to "Key Dates" and "Topics" to see abstract submission deadlines. The meeting will include: A Strong Applications-Oriented Workshop Program, A Vendor Exhibit Providing Access to the Latest Advances on...
Single-letter genetic variations within parts of the genome once dismissed as ‘junk DNA’ can increase cancer risk through wormhole-like effects on far-off genes, new research shows.
Researchers found that DNA sequences within ‘gene deserts’ – so called because they are completely devoid of genes – can regulate gene activity elsewhere by forming DNA loops across relatively large distances. The study, led by scientists at The Institute of Cancer Research, London, helps solve a mystery about how genetic variations in parts of the genome that don’t appear to be doing very much can increase cancer risk...
Awarded as part of £20M competition bringing innovative biotechnology projects to market
Cobra Biologics, international CDMO of biologics and pharmaceuticals, and The University of Manchester have been awarded collaborative funding of £217K as one of only 23 projects which will share almost £20M from the Innovate UK / Biotechnology and Biological Sciences Research Council (BBSRC) supported Industrial Biotechnology Catalyst. The joint project, PeriTune, is to develop a protein expression optimisation platform for the...
The Eco 48 real time PCR system from PCRmax, a Bibby Scientific company, has shown itself to have world leading uniformity of ??0.1?ŠC across the block, measured at 95 ?ŠC with no settle time.
In comparison to other systems, the Eco has proven that its unique heating and cooling system provides exceptionally accurate temperature control, so that researchers can always be completely confident in their results. One failed run in Next Generation Sequencing is a huge cost on the laboratory, and so by implementing the Eco system, there is potential for significant cost savings. The instrument is reliable for 430,000 cycles, still...
Handheld pipetting requires considerable experience and expertise to achieve reproducible results in applications such as serial dilution.
Serial dilutions can be difficult to perform reproducibly due to the many mixing steps that are required. The INTEGRA VIAFLO ASSIST enables scientists of all pipetting skill levels to achieve better serial dilution results. To use the VIAFLO ASSIST, simply mount a VIAFLO II electronic pipette onto the pipette adapter, define the number of mixing cycles, speed and mix volume, and press the run button. VIAFLO ASSIST will then obtain the protocol via Bluetooth from the VIAFLO II electronic pipette and automatically execute it.
New Webinar on Integrating DoE Tools and ambr® 15 Micro Bioreactors
Featuring a Case Study Showing how this Combined Technology can Reduce Timelines for Process Optimisation. Sartorius Stedim Biotech (SSB) today announced that it will be presenting a new bioprocess webinar on Wednesday, March 18th at 9am GMT (10am CET / 2.30pm IST/ 5pm China Standard Time) and again at 4pm GMT (8am PST/11am EST). The live events will detail how to use the new ambr® 15 automated micro...
Frost & Sullivan finds that direct to consumer genomics, which were close to absent a decade ago, are currently thriving
As the era of personalized medicine dawns on healthcare, the need to understand an individual’s genetic information through genomic testing has risen. This emerging branch of medicine has given birth to multiple companies that provide genetic tests to help end users understand their genetic profiles and assess their predisposition to inherited and terminal diseases like Alzheimer’s and Parkinson’s. New analysis from Frost & Sullivan...
New report highlights how the nanoparticle device could save NHS millions of pounds a year and revolutionise kidney disease treatment
A new medical device which combines nanotechnology with a pregnancy tester could help diagnose and treat the 1 million people in the UK who don’t know they have kidney disease, a new report by the Institution of Mechanical Engineers reveals today. Developed by engineers in London, the £10 device can be used at home and could revolutionise kidney disease care in the UK, which currently costs the NHS over £1.4 billion...
A lot goes into selecting a laboratory balance. Let’s start with weight.
You’ll need to select a balance that displays sample weight to the resolution desired. This is described as readout. Readout can be to several decimal places presented in grams or milligrams. Select a balance with a weighing capacity in excess of the samples you plan to weigh. Some balances also specify the minimum load that can be placed on the weighing plate. Why is this you ask? If the sample weight is not much larger than the expected weighing...
Magritek, a leading provider of compact NMR and MRI instruments, report on the use of their Spinsolve Benchtop NMR spectrometer for reaction monitoring studies in the Cronin Group in the Chemistry Department of the University of Glasgow.
Professor Lee Cronin holds the Regius Chair of Chemistry at the University of Glasgow. Research in the Cronin Group is motivated by the fascination for complex chemical systems and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks. They are developing a new approach to the chemical sciences which they call Chemical Cybernetics. This combines...
A new whitepaper from Malvern Instruments provides detailed guidance on the analytical technologies that help to accelerate oral solid dosage (OSD) product formulation to a successful conclusion.
‘Analytical techniques with a place in the oral solid dosage formulation toolkit’ reviews the regulatory and QbD framework associated with OSD formulation and demonstrates how Malvern systems can be used to generate the data required. The goal of formulation is to incorporate an identified drug substance into a successful pharmaceutical product. The regulatory framework for OSD products highlights the need to comprehensively...
Cresset, innovative provider of computational chemistry software and services, announces that its drug discovery arm Re-Pharm Ltd has used Forge to identify novel anti-inflammatory activity for an existing drug, which is widely prescribed for other non-inflammatory conditions.
Re-Pharm was searching for drugs to be re-purposed against a new enzyme target. Using known ligands and a crystal structure as a starting point, they used Cresset’s Forge to build computational templates to match any compounds likely to be active at the new target. The results were screened and RP0217 was identified as an effective new anti-inflammatory agent. Re-Pharm has filed patents on RP0217 for a variety of disease indications...
Courses range from beginner and intermediate to advanced levels
This year there are more than 40 new courses added in subjects such as forensics, statistics, separations, LIMS, LC/GC, mass spectrometry, nanotechnology and lab management—to name a few.Pittcon is pleased to announce the 2015 Short Courses (March 7-12). With more than 100 from which to choose, there are a wide variety of classes covering relevant topics in food science, water/wastewater, environmental, life science...
Researchers at the Centre de research du Centre hospitalier universitaire de Sherbrooke (CRCHUS) unveiled today the results of a clinical study demonstrating equivalency between cyclotron-produced technetium (Tc-99m) and that produced in a nuclear reactor.
The result of many years of research, this major clinical breakthrough will significantly affect the quality and safety of care delivered to patients. Based on the study's findings, not only are the CRCHUS's medical-imaging research positioned as leaders in this area, they are demonstrating that tomorrow's supply of medical isotopes can be produced with a promising green technology. On hand for the announcement were the Minister of...
Researchers at University Medical Center (UMC) Utrecht are developing an innovative cancer treatment with the help of a grant from Alpe d’HuZes/Dutch Cancer Society (KWF) of nearly 300,000 euros.
The treatment involves the injection of radioactive beads into tumors, thereby enabling a very precise localized radiotherapy. Direct injection of radioactive beads may be an effective treatment of tumors that are difficult or impossible to remove surgically. This is the basic principle of medical biologist Dr. Frank Nijsen, dental surgeon Dr. Robert van Es and nuclear physician Dr. Marnix Lam of UMC Utrecht. They are working...
Hands-on learning and personalized consulting sessions for mass flow meter and controller users during the show
Alicat Scientific will bring a new learning program to Pittcon 2015, March 9 – 12, at the Ernest N. Morial Convention Center (New Orleans, Louisiana). The company’s display of mass flow and pressure instrumentation in booth number 2238 will be joined by a new series of educational and consulting sessions, Alicat U. Alicat meters and controllers measure mass flow using differential pressure, which results in a fast and accurate response. With a choice of up to...
A collaborative research project between Freeman Technology and GEA Pharma Systems is providing new insight to support the development of continuous tablet manufacturing processes, a long term goal for the pharmaceutical industry.
Both companies are investing significant resource in the project and it is expected to deliver further substantive results over the next quarter. Within the pharmaceutical industry the replacement of batch tablet production units with continuous manufacturing suites has the potential to significantly improve efficiency and reduce costs. Freeman Technology, a global leader in powder testing instrumentation, and GEA, a specialist provider...
A self-assembling catalyst helps to construct complex biological scaffolds
Terpenes and their derivatives exert important biological and pharmaceutical functions. Starting out from a few basic building blocks nature elegantly builds up complex structures. Chemically particularly challenging are bridged ring systems such as eucalyptol. Chemists at the Technische Universität München (TUM) have now developed a catalyst that initiates the formation of such compounds. A special feature of the catalyst...
Milestone payment triggered by first patient enrolment in the phase IIb clinical trial for refractory Crohn’s disease
TxCell SA (FR0010127662 – TXCL), a biotechnology company developing innovative, cost-effective, personalized T-cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today the receipt of the latest milestone payment of EUR 1 million from the Ovasave collaboration option, development and license agreement from Trizell (Trizell Holding SA)...
Experts from Northumbria University, Newcastle, are taking part in an international project to build the world?s biggest and most revolutionary solar telescope.
The $344 million (£220m) Daniel K Inouye Solar Telescope, to be known as DKIST, will be situated on Haleakala Mountain in Maui, Hawaii, and aims to unlock the secrets of the Sun. With a four-metre diameter primary mirror, the super-telescope will be able to pick up unprecedented detail on the Sun?s surface ? the equivalent of being able to examine a £1 coin from a distance of 100km. It is hoped that DKIST will address fundamental...
Pioneering prostate cancer drug abiraterone significantly extends the lives of men with advanced prostate cancer if given before chemotherapy, the results of a major phase III clinical trial have shown.
The results, published in Lancet Oncology, showed that men with advanced, aggressive prostate cancer lived more than four months longer on average if they received abiraterone before chemotherapy than if they did not. The trial, led in the UK by Professor Johann de Bono of The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust, could fill an important gap in previous evidence for abiraterone’s...
A worldwide study of the DNA of 100,000 women has discovered two new genetic variants associated with an increased risk of breast cancer.
The genetic variants are specifically linked to the most common form of breast cancer, oestrogen receptor positive, and provide important insights into how the disease develops. Scientists believe screening women for all the genetic variants so far identified could eventually pick out those at highest risk of breast cancer and improve strategies for preventing the disease. The study was led by scientists at The Institute of Cancer Research...
Researchers with new results in areas relevant to the meeting topics are encouraged to submit abstracts online. We are striving to ensure the broadest possible coverage and exchange of recent advances. Please go to the link to "Key Dates" and "Topics" to see abstract submission deadlines. The meeting will include: A Strong Applications-Oriented Workshop Program, A Vendor Exhibit Providing Access to the Latest Advances on...
Researchers found that DNA sequences within ‘gene deserts’ – so called because they are completely devoid of genes – can regulate gene activity elsewhere by forming DNA loops across relatively large distances. The study, led by scientists at The Institute of Cancer Research, London, helps solve a mystery about how genetic variations in parts of the genome that don’t appear to be doing very much can increase cancer risk...
Cobra Biologics, international CDMO of biologics and pharmaceuticals, and The University of Manchester have been awarded collaborative funding of £217K as one of only 23 projects which will share almost £20M from the Innovate UK / Biotechnology and Biological Sciences Research Council (BBSRC) supported Industrial Biotechnology Catalyst. The joint project, PeriTune, is to develop a protein expression optimisation platform for the...
In comparison to other systems, the Eco has proven that its unique heating and cooling system provides exceptionally accurate temperature control, so that researchers can always be completely confident in their results. One failed run in Next Generation Sequencing is a huge cost on the laboratory, and so by implementing the Eco system, there is potential for significant cost savings. The instrument is reliable for 430,000 cycles, still...
Featuring a Case Study Showing how this Combined Technology can Reduce Timelines for Process Optimisation. Sartorius Stedim Biotech (SSB) today announced that it will be presenting a new bioprocess webinar on Wednesday, March 18th at 9am GMT (10am CET / 2.30pm IST/ 5pm China Standard Time) and again at 4pm GMT (8am PST/11am EST). The live events will detail how to use the new ambr® 15 automated micro...
As the era of personalized medicine dawns on healthcare, the need to understand an individual’s genetic information through genomic testing has risen. This emerging branch of medicine has given birth to multiple companies that provide genetic tests to help end users understand their genetic profiles and assess their predisposition to inherited and terminal diseases like Alzheimer’s and Parkinson’s. New analysis from Frost & Sullivan...
A new medical device which combines nanotechnology with a pregnancy tester could help diagnose and treat the 1 million people in the UK who don’t know they have kidney disease, a new report by the Institution of Mechanical Engineers reveals today. Developed by engineers in London, the £10 device can be used at home and could revolutionise kidney disease care in the UK, which currently costs the NHS over £1.4 billion...
You’ll need to select a balance that displays sample weight to the resolution desired. This is described as readout. Readout can be to several decimal places presented in grams or milligrams. Select a balance with a weighing capacity in excess of the samples you plan to weigh. Some balances also specify the minimum load that can be placed on the weighing plate. Why is this you ask? If the sample weight is not much larger than the expected weighing...
Professor Lee Cronin holds the Regius Chair of Chemistry at the University of Glasgow. Research in the Cronin Group is motivated by the fascination for complex chemical systems and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks. They are developing a new approach to the chemical sciences which they call Chemical Cybernetics. This combines...
‘Analytical techniques with a place in the oral solid dosage formulation toolkit’ reviews the regulatory and QbD framework associated with OSD formulation and demonstrates how Malvern systems can be used to generate the data required. The goal of formulation is to incorporate an identified drug substance into a successful pharmaceutical product. The regulatory framework for OSD products highlights the need to comprehensively...
Re-Pharm was searching for drugs to be re-purposed against a new enzyme target. Using known ligands and a crystal structure as a starting point, they used Cresset’s Forge to build computational templates to match any compounds likely to be active at the new target. The results were screened and RP0217 was identified as an effective new anti-inflammatory agent. Re-Pharm has filed patents on RP0217 for a variety of disease indications...
This year there are more than 40 new courses added in subjects such as forensics, statistics, separations, LIMS, LC/GC, mass spectrometry, nanotechnology and lab management—to name a few.Pittcon is pleased to announce the 2015 Short Courses (March 7-12). With more than 100 from which to choose, there are a wide variety of classes covering relevant topics in food science, water/wastewater, environmental, life science...
The result of many years of research, this major clinical breakthrough will significantly affect the quality and safety of care delivered to patients. Based on the study's findings, not only are the CRCHUS's medical-imaging research positioned as leaders in this area, they are demonstrating that tomorrow's supply of medical isotopes can be produced with a promising green technology. On hand for the announcement were the Minister of...
The treatment involves the injection of radioactive beads into tumors, thereby enabling a very precise localized radiotherapy. Direct injection of radioactive beads may be an effective treatment of tumors that are difficult or impossible to remove surgically. This is the basic principle of medical biologist Dr. Frank Nijsen, dental surgeon Dr. Robert van Es and nuclear physician Dr. Marnix Lam of UMC Utrecht. They are working...
Alicat Scientific will bring a new learning program to Pittcon 2015, March 9 – 12, at the Ernest N. Morial Convention Center (New Orleans, Louisiana). The company’s display of mass flow and pressure instrumentation in booth number 2238 will be joined by a new series of educational and consulting sessions, Alicat U. Alicat meters and controllers measure mass flow using differential pressure, which results in a fast and accurate response. With a choice of up to...
Both companies are investing significant resource in the project and it is expected to deliver further substantive results over the next quarter. Within the pharmaceutical industry the replacement of batch tablet production units with continuous manufacturing suites has the potential to significantly improve efficiency and reduce costs. Freeman Technology, a global leader in powder testing instrumentation, and GEA, a specialist provider...
Terpenes and their derivatives exert important biological and pharmaceutical functions. Starting out from a few basic building blocks nature elegantly builds up complex structures. Chemically particularly challenging are bridged ring systems such as eucalyptol. Chemists at the Technische Universität München (TUM) have now developed a catalyst that initiates the formation of such compounds. A special feature of the catalyst...
TxCell SA (FR0010127662 – TXCL), a biotechnology company developing innovative, cost-effective, personalized T-cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today the receipt of the latest milestone payment of EUR 1 million from the Ovasave collaboration option, development and license agreement from Trizell (Trizell Holding SA)...
The $344 million (£220m) Daniel K Inouye Solar Telescope, to be known as DKIST, will be situated on Haleakala Mountain in Maui, Hawaii, and aims to unlock the secrets of the Sun. With a four-metre diameter primary mirror, the super-telescope will be able to pick up unprecedented detail on the Sun?s surface ? the equivalent of being able to examine a £1 coin from a distance of 100km. It is hoped that DKIST will address fundamental...
The results, published in Lancet Oncology, showed that men with advanced, aggressive prostate cancer lived more than four months longer on average if they received abiraterone before chemotherapy than if they did not. The trial, led in the UK by Professor Johann de Bono of The Institute of Cancer Research, London, and The Royal Marsden NHS Foundation Trust, could fill an important gap in previous evidence for abiraterone’s...