Michigan researchers use Raman spectroscopy to study various childhood diseases
Renishaw, a world leader in metrology and spectroscopy, reports on the use of its inVia confocal Raman microscope in the study of various diseases–with a major focus on childhood diseases–at the Children's Hospital of Michigan and Wayne State University. Dr Michael Klein is a surgeon with the Children's Hospital of Michigan–a part of the Detroit Medical Center (DMC)–and a researcher with the Department of Surgery at Wayne...
Dekkera bruxellensis (D. bruxellensis) is a yeast native to the Belgian Senne valley located near Brussels. It is a hemiascomycetes yeast, meaning primitive and morphologically simple, with an absent or poorly developed mycelium and no formation of hyphae.
Its genome size ranges from under 20 to over 30 mega base pairs (Mb). The asexual reproductive form in the life cycle of this organism is known as Brettanomyces bruxellensis (B. bruxellensis), one of several members of the genus Brettanomyces. In the wild this microorganism lives on the skins of fruit and plays a key role in the production of Belgian Lambic style beers. Belgium’s beer and wine tradition is no newcomer to the alcoholic beverage industry. Belgium’s monastic, spontaneously fermenting lambic wheat beer family predates the pitching of yeast by brewers, whilst fermenting of beers with cherry (Kriek) and raspberry (Framboise) and spiced white brews predate the hop....
Aske Stephenson, a pioneering alcoholic beverage manufacturer, who will be using benchtop laboratory instruments from Bibby Scientific such as the Stuart® RE300 Rotary Evaporator to produce innovative pre-bottled cocktails.
Aske Stephenson specialises in developing hand-produced cocktails that are designed to introduce consumers to new and unusual flavour combinations, using a scientific approach that pushes taste boundaries. Bibby Scientific’s Stuart Rotary Evaporators are extremely reliable, safe and user-friendly instruments that are used widely in chemistry laboratories in universities and pharmaceutical companies. The Rotary Evaporators can also operate under vacuum, making them perfect for the unique distillation requirements of Aske Stephenson’s cocktail mixology....
Cresset, innovative provider of software and contract research services for small molecule discovery and design, is pleased to announce that Cancer Therapeutics CRC (CTx), a collaborative partnership of leading research institutes, universities and biotechnology companies in Australia, has licensed the virtual screening software Blaze for cancer research.
Blaze will be used to run virtual screening projects to translate Australia’s innovative research discoveries into new cancer drugs. “Cresset’s Blaze virtual screening platform was the obvious choice for us as it has a proven track record,” says Warwick Tong, Chief Executive Officer at CTx. “With access to a super computer at the Commonwealth Scientific and Industrial Research Organization (CSIRO) we now have the capability to run virtual...
Scientists have designed a novel method for improving the delivery of therapeutic molecules into diseased cells such as those found in cancer and tuberculosis
Many drug treatments do not work in patients because of their poor ability to reach their intended targets that lie inside cells. To address this, researchers from Cardiff University’s Schools of Pharmacy and Pharmaceutical Sciences, and Biosciences, sought to improve the delivery of a relatively new class of drugs called biotherapeutics. These drugs include antibodies, such as Herceptin, that target breast and stomach cancer cells. Cancer cells often...
Minister for Universities and Science Jo Johnson MP helped to break ground to mark the construction of a new University of Glasgow-led clinical imaging centre today (Monday 26 October).
The minister was visiting the site at the Queen Elizabeth University Hospital where the new Imaging Centre of Excellence (ICE) will be based. The ICE, supported by £16m of UK Government funding through the Medical Research Council as part of the Glasgow & Clyde Valley City Deal, will provide clinical research facilities which will be unique in the UK and create more than 200 new jobs for local people. The centre is expected to be...
OHAUS, a leading worldwide manufacturer of scales and balances, who recently announced the launch of Explorer® Semi-Micro, is now focused on gathering good weighing tips in order to simplify the weighing process and support the achievement of good results.
Weighing is one of the most basic tasks performed in the laboratory. That is why it is important we do not underestimate certain factors that can influence proper results. Incorrect usage or unsuitable conditions may cause errors, especially for semi-micro balances, that are used to weigh the lightest samples. OHAUS has been present on the market for over a 100 years and has always been concerned about the universal rules for good weighing as well as developing the perfect tools for that activity....
Read MoreACDOct 26, 2015
Use of next generation RNA In Situ Hybridization across a diverse array of applications
Advanced Cell Diagnostics Inc. (ACD), a technology and market leader in the field of molecular pathology and developer of cell and tissue-based RNA analysis tools, is celebrating a significant milestone. Over 300 peer-reviewed research papers have now been published that feature ACD’s RNAscope technology as a core part of the research methodology, reflecting its facility in advancing the latest biological research in both academia and industry. RNA in situ hybridization (ISH) is a valuable tool for studying...
Pittcon and its sponsoring society, The Society for Analytical Chemists of Pittsburgh (SACP) are pleased to announce Sanford Asher as the recipient of the 2016 SACP Award.
Asher will accept this prestigious award at Pittcon 2016 which takes place March 6-10, in Atlanta, Georgia. His session, “Photonic Crystal Hydrogel and Organogel Sensors for Chemical and Biological Analytes,” will include a discussion of sensing motifs that utilize 2-D and 3-D arrays and monolayers of particles embedded onto a molecular recognition polymer hydrogel networks. The SACP Analytical Chemistry Award, established in 1957, is presented annually to recognize outstanding...
Studies confirm utility of PointMan for molecular analysis of CTCs and circulating DNA in liquid biopsies
EKF Diagnostics, the global in vitro diagnostics company, announces that two research posters supporting the application of its PointMan™ DNA enrichment technology, for rapid and sensitive detection of lung cancer mutations, have been delivered at key conferences. Both posters are available at www.ekfmolecular.com. At the recent International Association for the Study of Lung Cancer’s 16th World Conference on Lung Cancer held in...
Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their temperature controlled stages in the study of the novel electrolytes that can be used in fuel cells.
This work was carried out at the Katholic University of Leuven in Belgium. The Katholic University of Leuven in central Belgium provides nine clusters, or Key Areas, of scientific research. The Centre for Surface Chemistry and Catalysis is a group within the Department of Microbial and Molecular Systems, M2S. Fuel cells are one of the key areas of research. Fuel cells, and in particular polymer electrolyte membrane fuel cells (PEMFCs) have been earmarked as highly...
University of Leicester, Loughborough University and University Hospitals of Leicester NHS Trust experts lead development of the East Midlands Breathomics Pathology Node
Researchers from the University of Leicester are leading the establishment of a new Centre to develop breath analysis tests that could help in the rapid diagnosis and treatment for a range of conditions, including cancers, respiratory infections and diseases such as asthma and chronic obstructive pulmonary disease. The East Midlands Breathomics Pathology Node (EMBER) has been established with a £2.5 million grant from the Medical Research...
Protagen AG, the technology leader in the development of novel molecular diagnostic and companion diagnostic tests for autoimmune diseases, has elected Dr. Dirk Ehlers, CEO of Trumpf Medical in Puchheim, to the company‘s Supervisory Board.
Simultaneously, Ulrich Kintzel, Senior Investment Manager of NRW.BANK in Düsseldorf, succeeded Dr. Aristotelis Nastos as representative of NRW.BANK, and Matthias Guth, was appointed by MIG AG in Munich, to follow Michael Motschmann in his board position. Dr. Ehlers has served in executive positions at Eppendorf, Roche Diagnostics, Evotec, Fresenius Kabi and Olympus Diagnostics and has a proven track record in the Diagnostics...
In advance of the 2015 Nobel Prize announcement, Preservica future proofs over 1m pages of the 1962 DNA Prize winning collection, including the famous ‘Photo 51’
Wellcome Library chooses Preservica to safeguard its online medical resource, as collection grows rapidly beyond 12 million images (20TB) The Wellcome Library, one of the world’s most significant resources for medical history, and part of the Wellcome Collection, has partnered with Preservica to protect and future proof its 20TB and growing collection of digitised and born digital material. The Wellcome Library is one of the world's major resources...
Analytik, leading suppliers of innovative analytical instrumentation, report on how the National Physical Laboratory applies the ASD, a PANalytical company FieldSpec 4 analyser to study vegetation to compare with data recorded from satellites.
The Environmental Division of the National Physical Laboratory (NPL) has a group which specialises in the investigation of the quality of Earth Observation satellite data. The TREES group (TRaceability in tErrestrial vEgetation Sensors and biophysical products) aims to provide end-to-end traceability for terrestrial vegetation sensors and satellite-derived products of biophysical Essential Climate Variables (ECVs) through a range of research activities...
Haydale, a leader in the development and commercialisation of enhanced graphene and nanoparticulate materials, has announced that it has recently been awarded a number of research grants, totalling over £450,000.
The projects relating to each grant are expected to run for a period of between 18 to 24 months. These new projects include The development of low cost, self-cleaning graphene enhanced coatings for industrial membranes used in the cleaning and filtering of waste water, swimming pools, desalination and offshore drilling fluids, amongst others as part of the project recently announced by G20 Water. The project’s target sectors of nanofiltration from...
Ingenza is collaborating with researchers at Plymouth University to develop an efficient, scalable microbial production system for epidermicin, an exciting new antibiotic that rapidly kills methicillin-resistant Staphylococcus aureus (MRSA) and other harmful bacteria.
Mathew Upton, Associate Professor in Medical Microbiology at Plymouth University, explained: “Epidermicin is a stable, 51 amino acid peptide originally found in Staphylococcus epidermidis, which is effective against gram-positive bacteria such as staphylococci, streptococci and enterococci. It is more potent than existing antibiotics, is non-toxic and represents a new tool in the arsenal of antibiotic medications. However, epidermicin is produced in...
Genomics’ proprietary statistical analysis tools and integrated multi-phenotype database will be used to inform Biogen’s drug research and development processes
Genomics plc (“Genomics”), a leading analysis company developing algorithms, data resources, and software solutions to uncover the relationships between genetic variation and human disease, today announced that it has entered into a collaboration agreement with Biogen. The collaboration aims to refine drug target selection through the use of sophisticated analysis of human genetic data. Under the terms of the agreement Biogen...
Presents data on how scientists at Merck are using the ambr® 250 system as a tool for rapid development of both cell culture bioprocesses and microbial fermentation
Sartorius Stedim Biotech (SSB) today announced a new paper entitled, ‘Automated disposable small-scale bioreactor reactor for high-throughput process development: implementation of the 24 bioreactor array’ has been published in the respected, peer reviewed journal, Pharmaceutical Bioprocessing. The paper details how scientists at leading pharmaceutical firm, Merck are utilising the ambr® 250 automated mini bioreactor system to improve process...
A new technical study from Micronic reports on tests carried out to demonstrate the absence of extractable organic contaminants in their polypropylene sample storage tubes.Extractables-free sample storage
The possibility of extractables being leached out of polypropylene tubes by aqueous or organic solvents is a major concern to many organisations looking to safeguard their valuable stored samples from contamination. In the tests carried out, samples of Micronic polypropylene sample storage tubes were extracted with 10% absolute ethanol in ultrapure water and the extract was then analysed using highly sensitive GC-FID and GC-MS instrumentation...
Magritek, a leading provider of compact NMR and MRI instruments, report on the use of their Spinsolve Benchtop NMR spectrometer in the Chemistry Department of Durham University.
It is being applied to general NMR research, reaction monitoring and teaching at the undergraduate level. Dr Alan Kenwright is Reader in Spectroscopy and Manager of the solution-state NMR facility in the Chemistry Department at Durham University. His personal research is focussed on developing and using NMR techniques to solve a range of chemical problems, but in addition to that (and growing out of it), he works in collaboration with a number of other...
Water is an unwanted constituent of all kinds of gases. Precise determination is therefore a must, e. g., in medical gases, noble gases, process gases, and welding gases.
The 875 KF Gas Analyzer is a highly robust solution for this kind of analysis, combining precise sampling with the accuracy of coulometric Karl Fischer titration in a fully integrated, software controlled analyzer. Water can be determined with various analytical techniques at trace levels. However, water in gases is a particular challenge: Most of the feasible methods need to be calibrated and can only determine the water content indirectly.
Renishaw, a world leader in metrology and spectroscopy, reports on the use of its inVia confocal Raman microscope in the study of various diseases–with a major focus on childhood diseases–at the Children's Hospital of Michigan and Wayne State University. Dr Michael Klein is a surgeon with the Children's Hospital of Michigan–a part of the Detroit Medical Center (DMC)–and a researcher with the Department of Surgery at Wayne...
Blaze will be used to run virtual screening projects to translate Australia’s innovative research discoveries into new cancer drugs. “Cresset’s Blaze virtual screening platform was the obvious choice for us as it has a proven track record,” says Warwick Tong, Chief Executive Officer at CTx. “With access to a super computer at the Commonwealth Scientific and Industrial Research Organization (CSIRO) we now have the capability to run virtual...
Many drug treatments do not work in patients because of their poor ability to reach their intended targets that lie inside cells. To address this, researchers from Cardiff University’s Schools of Pharmacy and Pharmaceutical Sciences, and Biosciences, sought to improve the delivery of a relatively new class of drugs called biotherapeutics. These drugs include antibodies, such as Herceptin, that target breast and stomach cancer cells. Cancer cells often...
The minister was visiting the site at the Queen Elizabeth University Hospital where the new Imaging Centre of Excellence (ICE) will be based. The ICE, supported by £16m of UK Government funding through the Medical Research Council as part of the Glasgow & Clyde Valley City Deal, will provide clinical research facilities which will be unique in the UK and create more than 200 new jobs for local people. The centre is expected to be...
Advanced Cell Diagnostics Inc. (ACD), a technology and market leader in the field of molecular pathology and developer of cell and tissue-based RNA analysis tools, is celebrating a significant milestone. Over 300 peer-reviewed research papers have now been published that feature ACD’s RNAscope technology as a core part of the research methodology, reflecting its facility in advancing the latest biological research in both academia and industry. RNA in situ hybridization (ISH) is a valuable tool for studying...
Asher will accept this prestigious award at Pittcon 2016 which takes place March 6-10, in Atlanta, Georgia. His session, “Photonic Crystal Hydrogel and Organogel Sensors for Chemical and Biological Analytes,” will include a discussion of sensing motifs that utilize 2-D and 3-D arrays and monolayers of particles embedded onto a molecular recognition polymer hydrogel networks. The SACP Analytical Chemistry Award, established in 1957, is presented annually to recognize outstanding...
EKF Diagnostics, the global in vitro diagnostics company, announces that two research posters supporting the application of its PointMan™ DNA enrichment technology, for rapid and sensitive detection of lung cancer mutations, have been delivered at key conferences. Both posters are available at www.ekfmolecular.com. At the recent International Association for the Study of Lung Cancer’s 16th World Conference on Lung Cancer held in...
This work was carried out at the Katholic University of Leuven in Belgium. The Katholic University of Leuven in central Belgium provides nine clusters, or Key Areas, of scientific research. The Centre for Surface Chemistry and Catalysis is a group within the Department of Microbial and Molecular Systems, M2S. Fuel cells are one of the key areas of research. Fuel cells, and in particular polymer electrolyte membrane fuel cells (PEMFCs) have been earmarked as highly...
Researchers from the University of Leicester are leading the establishment of a new Centre to develop breath analysis tests that could help in the rapid diagnosis and treatment for a range of conditions, including cancers, respiratory infections and diseases such as asthma and chronic obstructive pulmonary disease. The East Midlands Breathomics Pathology Node (EMBER) has been established with a £2.5 million grant from the Medical Research...
Simultaneously, Ulrich Kintzel, Senior Investment Manager of NRW.BANK in Düsseldorf, succeeded Dr. Aristotelis Nastos as representative of NRW.BANK, and Matthias Guth, was appointed by MIG AG in Munich, to follow Michael Motschmann in his board position. Dr. Ehlers has served in executive positions at Eppendorf, Roche Diagnostics, Evotec, Fresenius Kabi and Olympus Diagnostics and has a proven track record in the Diagnostics...
Wellcome Library chooses Preservica to safeguard its online medical resource, as collection grows rapidly beyond 12 million images (20TB) The Wellcome Library, one of the world’s most significant resources for medical history, and part of the Wellcome Collection, has partnered with Preservica to protect and future proof its 20TB and growing collection of digitised and born digital material. The Wellcome Library is one of the world's major resources...
The Environmental Division of the National Physical Laboratory (NPL) has a group which specialises in the investigation of the quality of Earth Observation satellite data. The TREES group (TRaceability in tErrestrial vEgetation Sensors and biophysical products) aims to provide end-to-end traceability for terrestrial vegetation sensors and satellite-derived products of biophysical Essential Climate Variables (ECVs) through a range of research activities...
The projects relating to each grant are expected to run for a period of between 18 to 24 months. These new projects include The development of low cost, self-cleaning graphene enhanced coatings for industrial membranes used in the cleaning and filtering of waste water, swimming pools, desalination and offshore drilling fluids, amongst others as part of the project recently announced by G20 Water. The project’s target sectors of nanofiltration from...
Mathew Upton, Associate Professor in Medical Microbiology at Plymouth University, explained: “Epidermicin is a stable, 51 amino acid peptide originally found in Staphylococcus epidermidis, which is effective against gram-positive bacteria such as staphylococci, streptococci and enterococci. It is more potent than existing antibiotics, is non-toxic and represents a new tool in the arsenal of antibiotic medications. However, epidermicin is produced in...
Genomics plc (“Genomics”), a leading analysis company developing algorithms, data resources, and software solutions to uncover the relationships between genetic variation and human disease, today announced that it has entered into a collaboration agreement with Biogen. The collaboration aims to refine drug target selection through the use of sophisticated analysis of human genetic data. Under the terms of the agreement Biogen...
Sartorius Stedim Biotech (SSB) today announced a new paper entitled, ‘Automated disposable small-scale bioreactor reactor for high-throughput process development: implementation of the 24 bioreactor array’ has been published in the respected, peer reviewed journal, Pharmaceutical Bioprocessing. The paper details how scientists at leading pharmaceutical firm, Merck are utilising the ambr® 250 automated mini bioreactor system to improve process...
The possibility of extractables being leached out of polypropylene tubes by aqueous or organic solvents is a major concern to many organisations looking to safeguard their valuable stored samples from contamination. In the tests carried out, samples of Micronic polypropylene sample storage tubes were extracted with 10% absolute ethanol in ultrapure water and the extract was then analysed using highly sensitive GC-FID and GC-MS instrumentation...
It is being applied to general NMR research, reaction monitoring and teaching at the undergraduate level. Dr Alan Kenwright is Reader in Spectroscopy and Manager of the solution-state NMR facility in the Chemistry Department at Durham University. His personal research is focussed on developing and using NMR techniques to solve a range of chemical problems, but in addition to that (and growing out of it), he works in collaboration with a number of other...
The 875 KF Gas Analyzer is a highly robust solution for this kind of analysis, combining precise sampling with the accuracy of coulometric Karl Fischer titration in a fully integrated, software controlled analyzer. Water can be determined with various analytical techniques at trace levels. However, water in gases is a particular challenge: Most of the feasible methods need to be calibrated and can only determine the water content indirectly.