AYOXXA Biosystems GmbH, an international biotechnology company, is one of two industrial partners of EYE-RISK, a large biomedical consortium bringing together the expertise of ten renown scientific and clinical institutions and a patient organization from six European countries.
It is led by Prof. Dr. Marius Ueffing of the University Medical Center of Tübingen, Germany and Prof. Dr. Caroline Klaver of the Erasmus University Medical Center Rotterdam, Netherlands. AYOXXA contributes the LUNARIS™ technology platform to develop biomarker footprints to stratify patient subgroups. The program is funded by the Horizon 2020 Research and Innovation Program of the European Union, aiming to study the combined...
Prior Scientific has announced that the Core Imaging Facility at the UK's prestigious National Institute for Medical Research (NIMR) has chosen a Prior HLD117 linear motor stage to be the sample platform at the centre of a new system based around an Olympus IX83 microscope.
NIMR is one of the world’s leading medical research institutes. It is dedicated to studying important questions about biological processes that are relevant to all aspects of health. Research at NIMR covers a broad spectrum of basic biomedical science, including infectious diseases, immunology, cell and developmental biology, neuroscience and structural biology. The world-class facilities for research include biological imaging resources, the...
Synbiosis,a long-established, expert manufacturer of automated microbiological systems, is pleased to announce its ProtoCOL 3 automated colony counter is being used at a world-renowned UK vaccine research facility, the Oxford Vaccine Group to speed up throughput of their vaccine testing programmes.
Microbiologists in the Oxford Vaccine Group at the University of Oxford are using a ProtoCOL 3 to count colonies on their post SBA (serum bactericidal antibody) assay test plates to rapidly determine each vaccine’s potency from colony counts. Using the ProtoCOL 3 is helping this group’s immunologists to significantly increase their throughput when determining the efficacy of vaccines against capsular group B meningococcal...
The first installation of a new Orbitrap-based GC-MS/MS instrument, designed to bring the highest levels of detection and identification capabilities to GC-MS studies, has taken place at the Muenster Electrochemical Energy Technology (MEET) Battery Research Center, University of Muenster, Germany.
Under the direction of Prof. Dr. Martin Winter, the MEET focuses on the research and development of innovative electrochemical energy storage devices with a high energy density, longer durability, and maximum safety. Dr. Nowak, Head of Division, Analytics and Environmental Aspects, will be the first to use the new Thermo Scientific Q Exactive GC hybrid quadrupole-Orbitrap GC-MS/MS instrument for his lab, with the aim to...
Planning and developing new laboratories and research suites can provide an ideal platform to create a perfect environment for the research team to prosper and reach their potential.
A carefully planned laboratory can simplify day-to-day research and experimentation – making every day lab work simpler and increasing focus on the important tasks at hand. Here are a few tips to help you make the most out of your laboratory when planning the layout.
Pipettes are often the foundation of many laboratory processes and experiments, but for many researchers, pipettes require little thought to operate. Because of the simplicity of pipettes, many users overlook the need for maintenance. Like all precision tools, pipettes require regular calibration and maintenance to ensure accurate performance. A leading pipette manufacture and distributor has accumulated data suggesting that a significant...
In Alzheimer’s disease proteins clump together to long fibrils causing the death of nerve cells.
Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. Using the example of a small heat shock protein, researchers at the Technical University of Munich (TUM) and the Helmholtz Zentrum München have now uncovered how the protein interacts with other proteins. Small heat shock proteins are the “catastrophe aid workers” of the cell...
Unique System Proven to Improve Laboratory Workflow and Productivity at Sheffield Teaching Hospitals NHS Trust
Beckman Coulter is pleased to announce the results of recently commissioned independent trials of the new DxN VERIS Molecular Diagnostics System* which showed enhanced workflow and productivity over incumbent systems. UK trial was undertaken within The Department of Virology at Sheffield Teaching Hospitals NHS Foundation Trust, whose annual automated workload is approximately 105,000 serology samples...
A ChemiSens Calorimeter is helping researchers at Germany’s Max Planck Institute of Colloids and Interfaces to quantitatively evaluate polymerization reaction profiles and accurately determine end points.
Klaus Tauer, Leader of the Department of Colloid Chemistry’s Heterophase Polymerization – Polymer Dispersions Group, explained: “We do a lot of fundamental research, studying the heterophase polymerization processes used to produce latexes. We rely on a ChemiSens Calorimeter for this work, using it almost daily for three main purposes; heterophase polymerizations, to follow reaction kinetics, and as a tool for polymer synthesis...
Comparative study of tumor biopsy v noninvasive blood-based analyses published
EKF Diagnostics, the global in vitro diagnostics company, announces that results from a study involving EKF Molecular’s PointMan™ DNA enrichment technology have been published in Clinical Cancer Research [1], a journal of the American Association for Cancer Research which focusses on innovative clinical cancer research studies. The study comparing tumor biopsy with noninvasive blood-based analyses brings together...
University of Leicester researchers evaluate the effectiveness of testing methods
The process for screening for Type 2 diabetes or those at high risk of the condition needs “careful re-evaluation”, according to the first study on the effectiveness of testing methods. Diabetes screening has been advocated, yet information on the response and diagnostic rates of different screening strategies is not available. But researchers at the University of Leicester have now found that ‘multi-step’ programmes lead to more people responding...
Lab Innovations, the UK’s only event dedicated to laboratory equipment, technology and services, returns to Birmingham’s NEC on 4 & 5 November, with two new show initiatives.
This year’s show will see the launch of a Live Lab, where 8 leading lab suppliers, including Datech Scientific, Radleys, Bibby Scientific, Spectro Analytics, QCL and Asynt, will provide practical live demonstrations of their latest technologies. Also new for 2015 is the free-to-attend European Laboratory Research & Innovation Group (ELRIG) seminar programme. This will provide highly practical seminar sessions and learning opportunities...
A new technical study from Micronic reports on tests carried out to demonstrate the absence of extractable organic contaminants in their polypropylene sample storage tubes. Extractables-free sample storage
The possibility of extractables being leached out of polypropylene tubes by aqueous or organic solvents is a major concern to many organisations looking to safeguard their valuable stored samples from contamination. In the tests carried out, samples of Micronic polypropylene sample storage tubes were extracted with 10% absolute ethanol in ultrapure water and the extract was then analysed using highly sensitive GC-FID and GC-MS...
Cell History File designed as ‘cell passport’ for developers and manufacturers of tissue and cell based medicinal products
The Cell Therapy Catapult, the organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the availability of the Cell History File (CHF) template document. The Cell History File template has been developed in conjunction with the UK’s Medicines and Healthcare products Regulatory Agency (MHRA), the Human Tissue Authority (HTA) and...
BioTek Instruments recently donated $10,000 to the Pulmonary and Critical Care Division at the University of Vermont (UVM) College of Medicine, in Burlington, Vermont to support the program's research into lung health and disease.
A multi-disciplinary team of UVM engineers, physicians, researchers and senior engineering students will use the funds to develop a customized 3D bioprinter from an existing 3D printer without existing bio-capabilities. This will allow the development of novel, multi-perspective approaches for studying lung airways and lung regeneration. The 3D bioprinter modifications will be spearheaded and jointly coordinated by Patrick Lee, Ph.D., UVM...
INTEGRA has published a new white paper that discusses how observing good pipetting practice helps to achieve better results in serial dilution assays.
Preparation of reproducible serial dilution assays, especially in 384-well plates, is a challenging task because they require many pipetting actions and are highly dependent on an operator's technique and experience. However, observing good pipetting practice helps immensely to improve reproducibility and accuracy. In this white paper the author focuses on a selection of good pipetting techniques, which if maintained offer the best chance of...
AMSBIO has launched a unique series of monoclonal and polyclonal antibodies against S-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) that allows immunoassays to be used in methylation regulation research.
Methylation is involved in nearly every aspect of life. SAM is the sole methyl donor for a variety of methyl-transfer reactions in DNA, RNA, proteins, lipids, phosphilipids, hormones and neurotransmitters. Proper DNA methylation is essential for normal embryonic development. However, when the methyl-transferase gene is homozygously deleted, it is lethal. DNA improperly methylated has been found in many tumors. Alterations in...
East Midlands health and social care under the spotlight as regional awards recognise incredible innovations
The East Midlands Academic Health Science Network (EMAHSN) shines a light on health and social care as finalists from across the region, including two projects involving University of Leicester researchers, are announced in the second East Midlands Innovation in Healthcare awards. The shortlist highlights the astonishing range of innovations and ideas developed by frontline healthcare staff, local patients, charities, companies, GP surgeries...
Lonza, one of the market leaders in primary cells, has announced an increase in recent publications referencing its specialized BulletKit™ Growth and Differentiation Media.
These peer-reviewed papers highlight the versatility of the media kits, which are proving especially useful for researchers looking to transition from established cell lines to primary cell culture or when co-culturing different cell types, mostly due to their convenience, adaptability and ease-of-use. Researchers often work with established cell lines before transitioning to primary cells, as the former are usually easier to culture in the...
Horizon Discovery Group plc (LSE: HZD), the international life science company supplying research tools and services that power genomics research and the development of personalised medicines, announces today that its leveraged business unit has signed a programme in-licensing and option agreement with Servier, the independent French research-based pharmaceutical company.
The agreement is potentially worth over £50 million to Horizon in preclinical and clinical milestones, payments linked to net sales, and tiered royalties on future product sales. Horizon has in-licensed novel kinase inhibitors from Servier that exhibit great promise based on pre-clinical data for treatment of a range of cancer types but do not currently have a biomarker to define a sensitive patient population. Horizon will use its world-leading platform...
Trends and Challenges in Quality Assurance and Regulatory Compliance
The Sartorius Lab Technology Forum will focus on the latest trends and challenges in quality assurance and regulatory compliance. This is the perfect opportunity to share knowledge and novel approaches with industry leaders and peers. International experts from the pharmaceutical and biotech industry, universities and the National Regulatory & Safety Institutes will cover topics of high interest around quality control, development...
With its unrivalled sensitivity, the PlasmaQuant ® MS Elite delivers the lowest detection limits of any ICP-MS when measuring both organic and inorganic species of arsenic in food and beverages. The high toxicity of inorganic arsenic means regular monitoring of food products is important. Various seafoods for example contain high levels of the less toxic organic arsenic species. Therefore, the dangers of arsenic depend not only on the total concentration, but also its chemical forms which vary in terms of toxicity and bioavailability....
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It is led by Prof. Dr. Marius Ueffing of the University Medical Center of Tübingen, Germany and Prof. Dr. Caroline Klaver of the Erasmus University Medical Center Rotterdam, Netherlands. AYOXXA contributes the LUNARIS™ technology platform to develop biomarker footprints to stratify patient subgroups. The program is funded by the Horizon 2020 Research and Innovation Program of the European Union, aiming to study the combined...
NIMR is one of the world’s leading medical research institutes. It is dedicated to studying important questions about biological processes that are relevant to all aspects of health. Research at NIMR covers a broad spectrum of basic biomedical science, including infectious diseases, immunology, cell and developmental biology, neuroscience and structural biology. The world-class facilities for research include biological imaging resources, the...
Microbiologists in the Oxford Vaccine Group at the University of Oxford are using a ProtoCOL 3 to count colonies on their post SBA (serum bactericidal antibody) assay test plates to rapidly determine each vaccine’s potency from colony counts. Using the ProtoCOL 3 is helping this group’s immunologists to significantly increase their throughput when determining the efficacy of vaccines against capsular group B meningococcal...
Under the direction of Prof. Dr. Martin Winter, the MEET focuses on the research and development of innovative electrochemical energy storage devices with a high energy density, longer durability, and maximum safety. Dr. Nowak, Head of Division, Analytics and Environmental Aspects, will be the first to use the new Thermo Scientific Q Exactive GC hybrid quadrupole-Orbitrap GC-MS/MS instrument for his lab, with the aim to...
Pipettes are often the foundation of many laboratory processes and experiments, but for many researchers, pipettes require little thought to operate. Because of the simplicity of pipettes, many users overlook the need for maintenance. Like all precision tools, pipettes require regular calibration and maintenance to ensure accurate performance. A leading pipette manufacture and distributor has accumulated data suggesting that a significant...
Small heat shock proteins can counteract this effect. Scientists, therefore, hope to deploy them as agents in the treatment of neurodegenerative diseases. Using the example of a small heat shock protein, researchers at the Technical University of Munich (TUM) and the Helmholtz Zentrum München have now uncovered how the protein interacts with other proteins. Small heat shock proteins are the “catastrophe aid workers” of the cell...
Beckman Coulter is pleased to announce the results of recently commissioned independent trials of the new DxN VERIS Molecular Diagnostics System* which showed enhanced workflow and productivity over incumbent systems. UK trial was undertaken within The Department of Virology at Sheffield Teaching Hospitals NHS Foundation Trust, whose annual automated workload is approximately 105,000 serology samples...
Klaus Tauer, Leader of the Department of Colloid Chemistry’s Heterophase Polymerization – Polymer Dispersions Group, explained: “We do a lot of fundamental research, studying the heterophase polymerization processes used to produce latexes. We rely on a ChemiSens Calorimeter for this work, using it almost daily for three main purposes; heterophase polymerizations, to follow reaction kinetics, and as a tool for polymer synthesis...
EKF Diagnostics, the global in vitro diagnostics company, announces that results from a study involving EKF Molecular’s PointMan™ DNA enrichment technology have been published in Clinical Cancer Research [1], a journal of the American Association for Cancer Research which focusses on innovative clinical cancer research studies. The study comparing tumor biopsy with noninvasive blood-based analyses brings together...
The process for screening for Type 2 diabetes or those at high risk of the condition needs “careful re-evaluation”, according to the first study on the effectiveness of testing methods. Diabetes screening has been advocated, yet information on the response and diagnostic rates of different screening strategies is not available. But researchers at the University of Leicester have now found that ‘multi-step’ programmes lead to more people responding...
This year’s show will see the launch of a Live Lab, where 8 leading lab suppliers, including Datech Scientific, Radleys, Bibby Scientific, Spectro Analytics, QCL and Asynt, will provide practical live demonstrations of their latest technologies. Also new for 2015 is the free-to-attend European Laboratory Research & Innovation Group (ELRIG) seminar programme. This will provide highly practical seminar sessions and learning opportunities...
The possibility of extractables being leached out of polypropylene tubes by aqueous or organic solvents is a major concern to many organisations looking to safeguard their valuable stored samples from contamination. In the tests carried out, samples of Micronic polypropylene sample storage tubes were extracted with 10% absolute ethanol in ultrapure water and the extract was then analysed using highly sensitive GC-FID and GC-MS...
The Cell Therapy Catapult, the organisation dedicated to the growth of the UK cell and gene therapy industry by bridging the gap between scientific research and commercialisation, today announces the availability of the Cell History File (CHF) template document. The Cell History File template has been developed in conjunction with the UK’s Medicines and Healthcare products Regulatory Agency (MHRA), the Human Tissue Authority (HTA) and...
A multi-disciplinary team of UVM engineers, physicians, researchers and senior engineering students will use the funds to develop a customized 3D bioprinter from an existing 3D printer without existing bio-capabilities. This will allow the development of novel, multi-perspective approaches for studying lung airways and lung regeneration. The 3D bioprinter modifications will be spearheaded and jointly coordinated by Patrick Lee, Ph.D., UVM...
Preparation of reproducible serial dilution assays, especially in 384-well plates, is a challenging task because they require many pipetting actions and are highly dependent on an operator's technique and experience. However, observing good pipetting practice helps immensely to improve reproducibility and accuracy. In this white paper the author focuses on a selection of good pipetting techniques, which if maintained offer the best chance of...
Methylation is involved in nearly every aspect of life. SAM is the sole methyl donor for a variety of methyl-transfer reactions in DNA, RNA, proteins, lipids, phosphilipids, hormones and neurotransmitters. Proper DNA methylation is essential for normal embryonic development. However, when the methyl-transferase gene is homozygously deleted, it is lethal. DNA improperly methylated has been found in many tumors. Alterations in...
These peer-reviewed papers highlight the versatility of the media kits, which are proving especially useful for researchers looking to transition from established cell lines to primary cell culture or when co-culturing different cell types, mostly due to their convenience, adaptability and ease-of-use. Researchers often work with established cell lines before transitioning to primary cells, as the former are usually easier to culture in the...
The agreement is potentially worth over £50 million to Horizon in preclinical and clinical milestones, payments linked to net sales, and tiered royalties on future product sales. Horizon has in-licensed novel kinase inhibitors from Servier that exhibit great promise based on pre-clinical data for treatment of a range of cancer types but do not currently have a biomarker to define a sensitive patient population. Horizon will use its world-leading platform...
The Sartorius Lab Technology Forum will focus on the latest trends and challenges in quality assurance and regulatory compliance. This is the perfect opportunity to share knowledge and novel approaches with industry leaders and peers. International experts from the pharmaceutical and biotech industry, universities and the National Regulatory & Safety Institutes will cover topics of high interest around quality control, development...
With its unrivalled sensitivity, the PlasmaQuant ® MS Elite delivers the lowest detection limits of any ICP-MS when measuring both organic and inorganic species of arsenic in food and beverages. The high toxicity of inorganic arsenic means regular monitoring of food products is important. Various seafoods for example contain high levels of the less toxic organic arsenic species. Therefore, the dangers of arsenic depend not only on the total concentration, but also its chemical forms which vary in terms of toxicity and bioavailability....