Novel method of image analysis reveals how cancer cells manipulate their size to resist treatment. Cancer cells can shrink or super-size themselves to survive drug treatment or other challenges within their environment, researchers have discovered. Scientists at The Institute of Cancer Research, London, combined biochemical profiling technologies with mathematical analyses to reveal how genetic changes lead to differences in the size of cancer cells – and how these changes could be exploited by new treatments...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2023 LIMS Webcast series on Wednesday, February 15, with See How LIMS is Making a Splash in the Water/Wastewater Industry. This webcast will provide an update on some of the leading challenges water, wastewater, and environmental laboratories are facing today and focus on the ways in which some of the latest advances in laboratory automation and LIMS are addressing these challenges...
Chemists from the Chianese Group at Colgate University (NY, USA) have shared kinetic data obtained using the Asynt Multicell 10-position high pressure laboratory reactor in their recent paper, “The Key Role of the Latent N0H Group in Milstein’s Catalyst for Ester Hydrogenation”. Their characterisation of the mechanisms of Milstein’s catalysts has enabled greater understanding of the reactivity of these catalysts in ester hydrogenation...
New Virtual Powder Flow Course happening in February 2023 focusing on the properties of powders! Understanding the flow of powders is essential in many industrial applications. Anyone working with powdered materials has once experienced processability problems like a lack of flowability, heavy sticking on pipes and machine surfaces, or variability in dosage among many other examples...
In this Virtual Powder Flow Course, Granutools explore the properties of powders at different scales, from the interactions between the particles at the micro scale to the consequence on the powder processability. Then, you will learn how this new knowledge can be used to better understand the processability of powders through detailed case studies...
PhoreMost Ltd., the UK-based biopharmaceutical company dedicated to ‘Drugging the Undruggable®’ disease targets, and ThinkCyte K.K, a biotechnology company pioneering novel cell analysis and sorting instruments, has announced a strategic research partnership aimed at advancing modern phenotypic drug screening using artificial intelligence (AI)...
Agilent Technologies Inc. has announce that the U.S. Food and Drug Administration (FDA) has approved Agilent Resolution ctDx FIRST as a companion diagnostic (CDx) to identify advanced non-small cell lung cancer (NSCLC) patients with KRAS G12C mutations who may benefit from treatment with KRAZATITM (adagrasib). This is the first liquid biopsy NGS assay approved by the FDA as a CDx for the newly approved KRAZATI in advanced NSCLC and was developed in collaboration with Mirati Therapeutics...
Aptamer Group plc, the developer of novel Optimer® binders to enable innovation in the life sciences industry, announces a selection of new contract wins where Optimer technology is being explored by partners to offer new strategies for therapeutics and potentially offer improved assay sensitivity and selectivity over antibodies. Optimer binders are oligonucleotide-based affinity ligands generated through the in vitro Optimer platform, which can be used as antibody alternatives...
AMSBIO reports how the Faculty of Biological Sciences at the University of Leeds (UK) is using their specialty reagents for the production, visualization, and analysis of glycans and to investigate their interactions which are instrumental to the advance of glycobiology. Glycobiology is vital for many biological processes — from fertilization to inflammation — helping unlock information about interactions between carbohydrates and proteins...
Whole-genome sequencing of 35,000 de-identified, diverse genomic DNA samples will begin this month. Illumina Inc., a global leader in DNA sequencing and array-based technologies, and Nashville Biosciences LLC, a wholly owned subsidiary of Vanderbilt University Medical Center (VUMC), have announced an agreement with Amgen, a global biopharmaceutical company, to whole-genome sequence approximately 35,000 DNA samples...
The UK’s largest distributor of scientific instrumentation, SciMed, has released a new whitepaper that shares advice with the laboratory industry on ways it can become more sustainable without increasing costs or harming experimental efficiency. These include reducing the use of harmful solvents in procedures such as separations and extractions and using new technology that reduces utilities consumption in lab environments...
Field-based non-dispersive infra-red spectroscopy instrument produces results that were previously only possible using lab-based techniques. A new scientific report by Concawe, which reviewed field-based and lab-based methods of analysing oil-contaminated soils, determined that the InfraCal 2 ATR-SP total petroleum hydrocarbon (TPH) analyser is an effective instrument for measuring oil contamination of soil and water...
This new application note describes the analysis of 7 RNA markers (100 – 1000 bases) using the recently introduced bioinert YMC-Accura Triart Bio C4 column at pH 7 and 80 °C. While conventional column hardware leads to peak tailing and loss of recovery when analysing oligonucleotides, the bioinert coated YMC-Accura Triart Bio C4 column shows excellent recoveries and peak shapes for all 7 well resolved markers...
BioGrad is to open the UK's second largest biobank facility in Liverpool, as part of a £7.6m investment into a new headquarters at Wavertree Technology Park. In collaboration with the University of Leicester, BioGrad biobank has already welcomed up to 261,000 samples from the largest long-Covid study in the UK. Further partnerships with Liverpool Women’s Hospital and three private research companies will see BioGrad bank over one million human cell samples banked in its first year...
Staying ahead of the competition with INTEGRA Biosciences’ pipettes. Students of Technische Universität Braunschweig, Germany, used INTEGRA Biosciences’ VIAFLO electronic pipettes and EVOLVE manual pipettes to perform sample transfers and dilutions as part of their project for the 2022 iGEM competition. The pipettes helped the team to speed up liquid handling and increase pipetting accuracy, giving the students a competitive edge over their peers...
Asynt reports how the deepmatter® Group, with facilities in the UK, France and Germany, have developed the cloud-based SmartChemistry® platform to share chemical reaction and sensor data direct from the laboratory to allowing analysis of this information on an unprecedented scale. This single platform allows reaction data to be compiled from multiple data sources to provide...
Recent data released by Autoscribe Informatics shows the breadth of industries purchasing a Laboratory Information Management System (LIMS); many for the first time. This market analysis from recent projects shows the cross-section of clients is moving well beyond what many think of as the LIMS core market of Healthcare, Medical Devices, and Pharmaceuticals....
World-leading cancer researchers announce plans to create a new generation of treatments that target the ecosystems supporting cancer. Cancer is supported by complex ecosystems within the body which can be disrupted by cutting-edge new treatments and cures, world-leading cancer researchers conclude. Scientists and clinicians have come together to identify cancer’s reliance on the ecosystems of our body’s cells and signals as a major opportunity in the next five years of research and treatment...
When cancer is detected at an early stage, the rates of survival increase drastically, but today only a few cancer types are screened for. An international study led by researchers from Chalmers University of Technology, Sweden, shows that a new, previously untested method can easily find multiple types of newly formed cancers at the same time – including cancer types that are difficult to detect with comparable methods...
Ziath reports how a leading Dutch genome diagnostics lab is using their Mohawk semi-automated tube picker to retrieve DNA samples accurately and rapidly from their extensive biobank. The Genome Diagnostics Laboratory (AGDx) is centred at the VU Medical Centre in Amsterdam - the largest University Medical Centre in the Netherlands. Bringing together a network of medical specialists in
Exact Sciences Corp., a leading provider of cancer screening and diagnostic tests, announce that new data presentations supporting the clinical value of its Precision Oncology portfolio will be shared in ten abstracts and three presentations at the 2022 San Antonio Breast Cancer Symposium® (SABCS®). “The breadth of evidence presented at SABCS 2022 showcases Exact Sciences’ growing Precision Oncology portfolio...
The Central Teaching Laboratories and the Department of Chemistry at the University of Liverpool (UK) has published an in-depth study that reports upon their implementation of Asynt laboratory equipment across multiple undergraduate teaching modules as they strive to meet their primary sustainability goals, reducing waste and to become net zero by 2035...
Novel method of image analysis reveals how cancer cells manipulate their size to resist treatment. Cancer cells can shrink or super-size themselves to survive drug treatment or other challenges within their environment, researchers have discovered. Scientists at The Institute of Cancer Research, London, combined biochemical profiling technologies with mathematical analyses to reveal how genetic changes lead to differences in the size of cancer cells – and how these changes could be exploited by new treatments...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2023 LIMS Webcast series on Wednesday, February 15, with See How LIMS is Making a Splash in the Water/Wastewater Industry. This webcast will provide an update on some of the leading challenges water, wastewater, and environmental laboratories are facing today and focus on the ways in which some of the latest advances in laboratory automation and LIMS are addressing these challenges...
Chemists from the Chianese Group at Colgate University (NY, USA) have shared kinetic data obtained using the Asynt Multicell 10-position high pressure laboratory reactor in their recent paper, “The Key Role of the Latent N0H Group in Milstein’s Catalyst for Ester Hydrogenation”. Their characterisation of the mechanisms of Milstein’s catalysts has enabled greater understanding of the reactivity of these catalysts in ester hydrogenation...
New Virtual Powder Flow Course happening in February 2023 focusing on the properties of powders! Understanding the flow of powders is essential in many industrial applications. Anyone working with powdered materials has once experienced processability problems like a lack of flowability, heavy sticking on pipes and machine surfaces, or variability in dosage among many other examples...
In this Virtual Powder Flow Course, Granutools explore the properties of powders at different scales, from the interactions between the particles at the micro scale to the consequence on the powder processability. Then, you will learn how this new knowledge can be used to better understand the processability of powders through detailed case studies...
PhoreMost Ltd., the UK-based biopharmaceutical company dedicated to ‘Drugging the Undruggable®’ disease targets, and ThinkCyte K.K, a biotechnology company pioneering novel cell analysis and sorting instruments, has announced a strategic research partnership aimed at advancing modern phenotypic drug screening using artificial intelligence (AI)...
Agilent Technologies Inc. has announce that the U.S. Food and Drug Administration (FDA) has approved Agilent Resolution ctDx FIRST as a companion diagnostic (CDx) to identify advanced non-small cell lung cancer (NSCLC) patients with KRAS G12C mutations who may benefit from treatment with KRAZATITM (adagrasib). This is the first liquid biopsy NGS assay approved by the FDA as a CDx for the newly approved KRAZATI in advanced NSCLC and was developed in collaboration with Mirati Therapeutics...
Aptamer Group plc, the developer of novel Optimer® binders to enable innovation in the life sciences industry, announces a selection of new contract wins where Optimer technology is being explored by partners to offer new strategies for therapeutics and potentially offer improved assay sensitivity and selectivity over antibodies. Optimer binders are oligonucleotide-based affinity ligands generated through the in vitro Optimer platform, which can be used as antibody alternatives...
AMSBIO reports how the Faculty of Biological Sciences at the University of Leeds (UK) is using their specialty reagents for the production, visualization, and analysis of glycans and to investigate their interactions which are instrumental to the advance of glycobiology. Glycobiology is vital for many biological processes — from fertilization to inflammation — helping unlock information about interactions between carbohydrates and proteins...
Whole-genome sequencing of 35,000 de-identified, diverse genomic DNA samples will begin this month. Illumina Inc., a global leader in DNA sequencing and array-based technologies, and Nashville Biosciences LLC, a wholly owned subsidiary of Vanderbilt University Medical Center (VUMC), have announced an agreement with Amgen, a global biopharmaceutical company, to whole-genome sequence approximately 35,000 DNA samples...
The UK’s largest distributor of scientific instrumentation, SciMed, has released a new whitepaper that shares advice with the laboratory industry on ways it can become more sustainable without increasing costs or harming experimental efficiency. These include reducing the use of harmful solvents in procedures such as separations and extractions and using new technology that reduces utilities consumption in lab environments...
Field-based non-dispersive infra-red spectroscopy instrument produces results that were previously only possible using lab-based techniques. A new scientific report by Concawe, which reviewed field-based and lab-based methods of analysing oil-contaminated soils, determined that the InfraCal 2 ATR-SP total petroleum hydrocarbon (TPH) analyser is an effective instrument for measuring oil contamination of soil and water...
This new application note describes the analysis of 7 RNA markers (100 – 1000 bases) using the recently introduced bioinert YMC-Accura Triart Bio C4 column at pH 7 and 80 °C. While conventional column hardware leads to peak tailing and loss of recovery when analysing oligonucleotides, the bioinert coated YMC-Accura Triart Bio C4 column shows excellent recoveries and peak shapes for all 7 well resolved markers...
BioGrad is to open the UK's second largest biobank facility in Liverpool, as part of a £7.6m investment into a new headquarters at Wavertree Technology Park. In collaboration with the University of Leicester, BioGrad biobank has already welcomed up to 261,000 samples from the largest long-Covid study in the UK. Further partnerships with Liverpool Women’s Hospital and three private research companies will see BioGrad bank over one million human cell samples banked in its first year...
Staying ahead of the competition with INTEGRA Biosciences’ pipettes. Students of Technische Universität Braunschweig, Germany, used INTEGRA Biosciences’ VIAFLO electronic pipettes and EVOLVE manual pipettes to perform sample transfers and dilutions as part of their project for the 2022 iGEM competition. The pipettes helped the team to speed up liquid handling and increase pipetting accuracy, giving the students a competitive edge over their peers...
Asynt reports how the deepmatter® Group, with facilities in the UK, France and Germany, have developed the cloud-based SmartChemistry® platform to share chemical reaction and sensor data direct from the laboratory to allowing analysis of this information on an unprecedented scale. This single platform allows reaction data to be compiled from multiple data sources to provide...
Recent data released by Autoscribe Informatics shows the breadth of industries purchasing a Laboratory Information Management System (LIMS); many for the first time. This market analysis from recent projects shows the cross-section of clients is moving well beyond what many think of as the LIMS core market of Healthcare, Medical Devices, and Pharmaceuticals....
World-leading cancer researchers announce plans to create a new generation of treatments that target the ecosystems supporting cancer. Cancer is supported by complex ecosystems within the body which can be disrupted by cutting-edge new treatments and cures, world-leading cancer researchers conclude. Scientists and clinicians have come together to identify cancer’s reliance on the ecosystems of our body’s cells and signals as a major opportunity in the next five years of research and treatment...
When cancer is detected at an early stage, the rates of survival increase drastically, but today only a few cancer types are screened for. An international study led by researchers from Chalmers University of Technology, Sweden, shows that a new, previously untested method can easily find multiple types of newly formed cancers at the same time – including cancer types that are difficult to detect with comparable methods...
Ziath reports how a leading Dutch genome diagnostics lab is using their Mohawk semi-automated tube picker to retrieve DNA samples accurately and rapidly from their extensive biobank. The Genome Diagnostics Laboratory (AGDx) is centred at the VU Medical Centre in Amsterdam - the largest University Medical Centre in the Netherlands. Bringing together a network of medical specialists in
Exact Sciences Corp., a leading provider of cancer screening and diagnostic tests, announce that new data presentations supporting the clinical value of its Precision Oncology portfolio will be shared in ten abstracts and three presentations at the 2022 San Antonio Breast Cancer Symposium® (SABCS®). “The breadth of evidence presented at SABCS 2022 showcases Exact Sciences’ growing Precision Oncology portfolio...
The Central Teaching Laboratories and the Department of Chemistry at the University of Liverpool (UK) has published an in-depth study that reports upon their implementation of Asynt laboratory equipment across multiple undergraduate teaching modules as they strive to meet their primary sustainability goals, reducing waste and to become net zero by 2035...