Two key challenges in chemistry innovation are solved simultaneously by exploring chemical opportunities with artificial intelligence. Researchers in Japan have developed a machine learning process that simultaneously designs new molecules and suggests the chemical reactions to make them. The team, at the Institute of Statistical Mathematics (ISM) in Tokyo, published their results in the journal Science and Technology of Advanced Materials...
LynxDx, a Michigan diagnostics laboratory specializing in prostate cancer screening and risk prediction, acquired liquid handling solutions from INTEGRA Biosciences to streamline its sample preparation for high throughput COVID-19 testing. The lab is now in the process of moving these products over to prostate cancer screening, where they are helping to improve result accuracy and turnaround times and, ultimately, support timely diagnosis and treatment...
The Earlham Institute has been awarded £31.4m from the Biotechnology and Biological Sciences Research Council (BBSRC), part of UKRI, to deliver an ambitious programme of research, develop new technology, and deliver innovation and impact over the next five years. This investment covers two new strategic programmes of research - Cellular Genomics and Decoding Biodiversity - and two National Bioscience Research Infrastructures (NBRIs) - Transformative Genomics and the Earlham Biofoundry...
Have you read a ton of articles on phase contrast microscopy, but still can’t get the full picture? Well then, watch the second movie in the mini-movie series, “Microscopy With ibidi,” for a simple explanation of how this microscopy technique works. In this short movie, we will show you why this microscopy technique is so important for scientists. and how phase contrast makes almost transparent cells clearly visible...
An international team of scientists from The Institute of Cancer Research, London, and the Max Planck Institute for Multidisciplinary Sciences in Germany employed state-of-the-art biochemical and cryo-electron microscopy (cryo-EM) methods to study the spliceosome in intricate detail and answer long standing questions about how it works. The spliceosome operates like a nanobot, processing RNA – genetic instructions copied from DNA – in a key step to allow the building of complex proteins...
As the second leading cause of death worldwide, cancer has touched the lives of most Americans. In an effort to improve treatments for patients on Earth by better understanding how cancer spreads, a team of researchers is sending cancer organoids to space in an investigation sponsored by the International Space Station (ISS) National Laboratory. In collaboration with Axiom Space, researchers from the University of California San Diego and the Sanford Stem Cell Institute, will study the properties of cancer stem cells...
GenNext Technologies, Inc., a growth-stage company that provides structural biology instrumentation, software, and services, announce that it is collaborating with Emery Pharma, a full-service CRO offering end-to-end biologic drug development support. Through this partnership, GenNext and Emery Pharma will combine forces to provide best-in-class pharmaceutical functional and structural analysis for allosteric and mono-clonal antibody therapeutics...
A new method of controlling the shape of tiny particles about one tenth of the width of human hair could make the technology that powers our daily lives more stable and more efficient, scientists claim. The process, which transforms the structure of microscopic semiconductor materials known as quantum dots, provides industry with opportunities to optimise optoelectronics, energy harvesting, photonics, and biomedical imaging technologies, according to the Cardiff University-led team...
Blood clot researchers could benefit from a new device that mimics a human vein, replacing the need for animals for some studies. The vein-on-a-chip model has been developed by scientists at the University of Birmingham and can be used in experiments to understand mechanisms of blood clot formation. The device, described in a recent paper published in Frontiers in Cardiovascular Medicine, is a tiny channel, which includes structures called ‘valves’ that ensure the correct direction of blood flow...
Revvity, Inc. has announced a new license agreement with AstraZeneca for the technology underlying its Pin-point™ base editing system, a next-generation modular gene editing platform with a strong safety profile. Dr. Alan Fletcher, Senior Vice President, Life Sciences at Revvity, said, “Our fundamental goal for the Pin-point platform is to translate the technology from pre-clinical research into the clinic, and ultimately, impact patient lives...
INTEGRA Biosciences’ PIPETBOY acu 2 pipette controller is helping researchers in the Immune Sensing and Signaling Dynamics group/ImmunoHUB at the i3S in Porto, Portugal, to further their research into the role of the aryl hydrocarbon receptor (AHR) in infection and cancer. Research technician Sérgio Marinho explained: “The AHR is used by cells to monitor their microenvironment, providing molecular cues to identify changes in microbial communities or tumor status, as well as allowing the host to react to potential imbalances in homeostasis...
Intellegens has announced that it will lead a consortium to help accelerate the adoption of artificial intelligence (AI) methods such as machine learning (ML) in the UK materials and chemicals industries. The initial phase of the project, funded by Innovate UK KTN, part of UK Research and Innovation, will study factors that limit use of this technology. It will also recommend steps to increase trust and drive the application of AI/ML to optimise vital products and processes while reducing energy and resource consumption in pursuit of net zero goals...
Deluge of entries ensures one of the Society’s biggest and best ever competitions. This year’s RMS Scientific Imaging Competition has triggered a fantastic response from microscopists around the world – with 198 images submitted across seven different award categories. With the submissions deadline now expired, the competition judges have been left with the tricky task of whittling down a shortlist of images to be displayed at mmc2023, where the final decisions on the winners will be made...
Aston University has been named as one of the UK’s leading lights in what is predicted to be the future of food - lab-made meat. The University is one of 17 higher education institutions that are expected to play a major role in the development of cultivated meat. Cultivated or lab-grown meat is made from cells taken from animals via biopsy. The cells are used to create meat which doesn’t involve the slaughter of animals...
Scientists have developed new technology which has made it possible to isolate and study how a single protein – 10,000 times thinner than a human hair – behaves and changes over time. The Nottingham Trent University team says the work – the first of its kind – enables them to see how a protein behaves in its natural environment and that it could help better understand proteins linked to disease and how they might respond to certain therapies...
England’s first centre of its kind is set to make significant improvements in cancer diagnosis and treatment – by combining pioneering digital imaging with artificial intelligence. The Royal Marsden NHS Foundation Trust and its academic research partner The Institute of Cancer Research, London, have today announced the opening of their new joint Integrated Pathology Unit (IPU)...
Researchers at Emory University School of Medicine are streamlining their search for novel degenerative neurological disease biomarkers with INTEGRA Biosciences’ VOYAGER adjustable tip spacing pipettes. The Roberts Lab is developing a simple blood test to screen for the presence of protein and metalloprotein biomarkers of disorders such as Alzheimer’s, ALS and Parkinson’s, with the aim of accelerating trial recruitment and drug development for these diseases...
In support of global initiatives to advance molecular profiling in oncology, Thermo Fisher Scientific has announced the latest recipients of the Oncomine Clinical Research Grant and the opening of its submissions for Spring 2023. Grant recipients are leading the exploration of new and expanded applications for next-generation sequencing (NGS)-based testing so that more cancer patients can access the benefits of precision medicine...
Chronic wounds are a major health problem for diabetic patients and the elderly – in extreme cases they can even lead to amputation. Using electric stimulation, researchers in a project at Chalmers University of Technology, Sweden, and the University of Freiburg, Germany, have developed a method that speeds up the healing process, making wounds heal three times faster...
Prof. Dr. Immanuel Bloch, who is considered a leading quantum physicist, is to be commended with the ZEISS Research Award for his outstanding research in the field of quantum simulation using ultracold atoms. The company has been recognizing outstanding research in optics and photonics since 1990. The ceremony will take place at the Deutsches Museum in Munich on 26 June 2023. Three young scientists from Germany, Austria and Switzerland will also receive awards. They will receive the Carl Zeiss Award for Young Researchers...
Chocolate...delicious for humans, challenging for analytical methods, perfect for demonstrating the benefits of high mass resolution PTR-TOFMS! The real-time, direct injection PTR technology combined with powerful TOF-MS enables rapid, highly selective and quantitative screening of food, flavor and fragrance samples. Recently, IONICON performed an extensive food and flavor study comparing their ultimate-resolution trace VOC analyzer PTR-TOF 10k to a common high-resolution PTR-TOFMS instrument...
When you pack for an extended trip, you usually bring everything you will need while you are away—food, clothing, medication, and other necessities. But what do you do if your trip takes you to space, where cargo room is extremely limited and expensive? A team of researchers from Rhodium Scientific and the University of Florida propose that you pack some useful microbes along with your essentials. These microbes could help make other products you might need during your stay...
Two key challenges in chemistry innovation are solved simultaneously by exploring chemical opportunities with artificial intelligence. Researchers in Japan have developed a machine learning process that simultaneously designs new molecules and suggests the chemical reactions to make them. The team, at the Institute of Statistical Mathematics (ISM) in Tokyo, published their results in the journal Science and Technology of Advanced Materials...
LynxDx, a Michigan diagnostics laboratory specializing in prostate cancer screening and risk prediction, acquired liquid handling solutions from INTEGRA Biosciences to streamline its sample preparation for high throughput COVID-19 testing. The lab is now in the process of moving these products over to prostate cancer screening, where they are helping to improve result accuracy and turnaround times and, ultimately, support timely diagnosis and treatment...
The Earlham Institute has been awarded £31.4m from the Biotechnology and Biological Sciences Research Council (BBSRC), part of UKRI, to deliver an ambitious programme of research, develop new technology, and deliver innovation and impact over the next five years. This investment covers two new strategic programmes of research - Cellular Genomics and Decoding Biodiversity - and two National Bioscience Research Infrastructures (NBRIs) - Transformative Genomics and the Earlham Biofoundry...
Have you read a ton of articles on phase contrast microscopy, but still can’t get the full picture? Well then, watch the second movie in the mini-movie series, “Microscopy With ibidi,” for a simple explanation of how this microscopy technique works. In this short movie, we will show you why this microscopy technique is so important for scientists. and how phase contrast makes almost transparent cells clearly visible...
An international team of scientists from The Institute of Cancer Research, London, and the Max Planck Institute for Multidisciplinary Sciences in Germany employed state-of-the-art biochemical and cryo-electron microscopy (cryo-EM) methods to study the spliceosome in intricate detail and answer long standing questions about how it works. The spliceosome operates like a nanobot, processing RNA – genetic instructions copied from DNA – in a key step to allow the building of complex proteins...
As the second leading cause of death worldwide, cancer has touched the lives of most Americans. In an effort to improve treatments for patients on Earth by better understanding how cancer spreads, a team of researchers is sending cancer organoids to space in an investigation sponsored by the International Space Station (ISS) National Laboratory. In collaboration with Axiom Space, researchers from the University of California San Diego and the Sanford Stem Cell Institute, will study the properties of cancer stem cells...
GenNext Technologies, Inc., a growth-stage company that provides structural biology instrumentation, software, and services, announce that it is collaborating with Emery Pharma, a full-service CRO offering end-to-end biologic drug development support. Through this partnership, GenNext and Emery Pharma will combine forces to provide best-in-class pharmaceutical functional and structural analysis for allosteric and mono-clonal antibody therapeutics...
A new method of controlling the shape of tiny particles about one tenth of the width of human hair could make the technology that powers our daily lives more stable and more efficient, scientists claim. The process, which transforms the structure of microscopic semiconductor materials known as quantum dots, provides industry with opportunities to optimise optoelectronics, energy harvesting, photonics, and biomedical imaging technologies, according to the Cardiff University-led team...
Blood clot researchers could benefit from a new device that mimics a human vein, replacing the need for animals for some studies. The vein-on-a-chip model has been developed by scientists at the University of Birmingham and can be used in experiments to understand mechanisms of blood clot formation. The device, described in a recent paper published in Frontiers in Cardiovascular Medicine, is a tiny channel, which includes structures called ‘valves’ that ensure the correct direction of blood flow...
Revvity, Inc. has announced a new license agreement with AstraZeneca for the technology underlying its Pin-point™ base editing system, a next-generation modular gene editing platform with a strong safety profile. Dr. Alan Fletcher, Senior Vice President, Life Sciences at Revvity, said, “Our fundamental goal for the Pin-point platform is to translate the technology from pre-clinical research into the clinic, and ultimately, impact patient lives...
INTEGRA Biosciences’ PIPETBOY acu 2 pipette controller is helping researchers in the Immune Sensing and Signaling Dynamics group/ImmunoHUB at the i3S in Porto, Portugal, to further their research into the role of the aryl hydrocarbon receptor (AHR) in infection and cancer. Research technician Sérgio Marinho explained: “The AHR is used by cells to monitor their microenvironment, providing molecular cues to identify changes in microbial communities or tumor status, as well as allowing the host to react to potential imbalances in homeostasis...
Intellegens has announced that it will lead a consortium to help accelerate the adoption of artificial intelligence (AI) methods such as machine learning (ML) in the UK materials and chemicals industries. The initial phase of the project, funded by Innovate UK KTN, part of UK Research and Innovation, will study factors that limit use of this technology. It will also recommend steps to increase trust and drive the application of AI/ML to optimise vital products and processes while reducing energy and resource consumption in pursuit of net zero goals...
Deluge of entries ensures one of the Society’s biggest and best ever competitions. This year’s RMS Scientific Imaging Competition has triggered a fantastic response from microscopists around the world – with 198 images submitted across seven different award categories. With the submissions deadline now expired, the competition judges have been left with the tricky task of whittling down a shortlist of images to be displayed at mmc2023, where the final decisions on the winners will be made...
Aston University has been named as one of the UK’s leading lights in what is predicted to be the future of food - lab-made meat. The University is one of 17 higher education institutions that are expected to play a major role in the development of cultivated meat. Cultivated or lab-grown meat is made from cells taken from animals via biopsy. The cells are used to create meat which doesn’t involve the slaughter of animals...
Scientists have developed new technology which has made it possible to isolate and study how a single protein – 10,000 times thinner than a human hair – behaves and changes over time. The Nottingham Trent University team says the work – the first of its kind – enables them to see how a protein behaves in its natural environment and that it could help better understand proteins linked to disease and how they might respond to certain therapies...
England’s first centre of its kind is set to make significant improvements in cancer diagnosis and treatment – by combining pioneering digital imaging with artificial intelligence. The Royal Marsden NHS Foundation Trust and its academic research partner The Institute of Cancer Research, London, have today announced the opening of their new joint Integrated Pathology Unit (IPU)...
Researchers at Emory University School of Medicine are streamlining their search for novel degenerative neurological disease biomarkers with INTEGRA Biosciences’ VOYAGER adjustable tip spacing pipettes. The Roberts Lab is developing a simple blood test to screen for the presence of protein and metalloprotein biomarkers of disorders such as Alzheimer’s, ALS and Parkinson’s, with the aim of accelerating trial recruitment and drug development for these diseases...
In support of global initiatives to advance molecular profiling in oncology, Thermo Fisher Scientific has announced the latest recipients of the Oncomine Clinical Research Grant and the opening of its submissions for Spring 2023. Grant recipients are leading the exploration of new and expanded applications for next-generation sequencing (NGS)-based testing so that more cancer patients can access the benefits of precision medicine...
Chronic wounds are a major health problem for diabetic patients and the elderly – in extreme cases they can even lead to amputation. Using electric stimulation, researchers in a project at Chalmers University of Technology, Sweden, and the University of Freiburg, Germany, have developed a method that speeds up the healing process, making wounds heal three times faster...
Prof. Dr. Immanuel Bloch, who is considered a leading quantum physicist, is to be commended with the ZEISS Research Award for his outstanding research in the field of quantum simulation using ultracold atoms. The company has been recognizing outstanding research in optics and photonics since 1990. The ceremony will take place at the Deutsches Museum in Munich on 26 June 2023. Three young scientists from Germany, Austria and Switzerland will also receive awards. They will receive the Carl Zeiss Award for Young Researchers...
Chocolate...delicious for humans, challenging for analytical methods, perfect for demonstrating the benefits of high mass resolution PTR-TOFMS! The real-time, direct injection PTR technology combined with powerful TOF-MS enables rapid, highly selective and quantitative screening of food, flavor and fragrance samples. Recently, IONICON performed an extensive food and flavor study comparing their ultimate-resolution trace VOC analyzer PTR-TOF 10k to a common high-resolution PTR-TOFMS instrument...
When you pack for an extended trip, you usually bring everything you will need while you are away—food, clothing, medication, and other necessities. But what do you do if your trip takes you to space, where cargo room is extremely limited and expensive? A team of researchers from Rhodium Scientific and the University of Florida propose that you pack some useful microbes along with your essentials. These microbes could help make other products you might need during your stay...