Uniqsis has published details of a new flow-through protocol developed by the Lamaty Group at Universite de Montpellier (France) on a FlowSyn™ Multi-X system that provides efficient ring closing olefin metathesis.

Olefin metathesis is an important reaction that provides a useful synthetic route to highly functionalized molecules such as drug precursors or polymers. Although this reaction is highly efficient in batch, scaling-up usually results in poor reproducibility. While several research groups have reported the development of olefin metathesis in continuous flow, most of them have focused on the use of a heterogeneous catalyst....

Goldfinch Bio’s researchers select StarDrop to guide successful drug discovery

Optibrium, a developer of software for small molecule discovery, and Goldfinch Bio, a company focused on discovering and developing precision therapies to treat patients with kidney disease, today announced that the company has signed a multi-year agreement to license Optibrium’s StarDrop software....

Deben reports on how the Marrow group in the Materials Department at the University of Oxford applies Deben’s mechanical stage for in situ µXCT studies of multiple engineering and natural materials. 

Professor James Marrow leads a research group specialising in the structure-property relationship of a broad range of engineering and natural materials. Based in the Materials Department at the University of Oxford, Marrow's team use high resolution X-ray computed tomography to make in situ studies of three-dimensional deformation and damage....

Phasefocus provides a range of products and services based on its proprietary Ptychographic Quantitative Phase Imaging (QPI) technology to provide a wide range of analytical applications including label-free cell imaging and quantitative electron phase microscopy.

Here, they report on a poster presented at ASCB that shows the power of Livecyte for individual cell segmentation. Professor Norman Maitland's team from the Cancer Research Unit at the University of York presented a poster that showed the potential of Phasefocus’ Livecyte label-free cell analysis system as a rapid characterisation tool of cell cultures derived from patient tissue. “Characterisation of the subpopulations of heterogeneous primary...

King Abdullah University of Science and Technology (KAUST) and Thermo Fisher Scientific Inc. held an opening ceremony on May 9 for the Electron Microscopy Center of Excellence at the KAUST campus in Thuwal, Saudi Arabia.

This new center builds upon the long-standing partnership between KAUST and Thermo Fisher, and will focus on excellence in instrument performance and R&D collaboration. The Center of Excellence aims to offer KAUST scientists and collaborators exploration and experimentation capabilities through Thermo Fisher’s leading electron microscopy platform...

Oxford Nanoimaging Limited manufacture and sell custom microscopes offering super-resolution and single-molecule capabilities to research users.

The BioMAN Laboratory is led by Professor Rizal Hariadi. Situated in the Biodesign Institute at Arizona State University, the super-resolution Nanoimager is being used to understand cell functionality emerging from interactions between proteins in healthy & disease states....

PerkinElmer, Inc. Provides Research-Use-Only Automated Immunoassay to Detect Creatine Kinase Muscle Isozyme in Dried Blood Spots

A new study published in Clinical Chemistry has revealed a potential automated assay for identifying Duchenne muscular dystrophy (Duchenne) in newborn babies. Duchenne is a progressive, X-chromosome linked neuromuscular disorder with a worldwide average incidence rate of approximately 1 in 5,000 babies....

Funding by entrepreneur Mr Jimmy Mayer to establish world’s first register of patients with disease that is one of the biggest causes of kidney failure globally

The University of Leicester has received its biggest ever single gift from a private  individual - £2.7 million- which will be used to fund life-saving kidney research of global significance in the College of Medicine, Biological Sciences and Psychology.

Genevac has published a customer report that describes an evaporative sample preparation protocol for highly sensitive analytical methods used to test foodstuffs, principally meat, fish and shellfish, for the presence of antibiotics. 

The analytical method calls for good upstream sample preparation to eliminate the effects of the matrix, and can be manual and time consuming, particularly where evaporation is concerned. The authors describe how the installation of the Genevac EZ-2 evaporator in their laboratory is estimated to save the laboratory 2-3 hours per day that previously was spent on evaporation tasks...

Isogenica Ltd, a leader in the design and construction of innovative and highly diverse synthetic antibody libraries, announces the availability of its new fully synthetic, human Fab fragment library.

An announcement was made at the 13^th annual PEGS meeting in Boston, MA by Guy Hermans, Isogenica’s CSO, who commented: “This novel fully synthetic antibody library, built using the company’s DNA library synthesis method (COLIBRA™), takes advantage of the most up to date understanding of the human antibody repertoire. Combining massive sequence diversity and dispersity with high functionality and developability, it offers the most efficient route to...

Allows German Researchers to Easily Detect Leukaemia Associated Proteins

Syngene, a world-leading manufacturer of image analysis solutions, is pleased to announce its PXi multi-application imager is being used by scientists at the prestigious Freie Universtät Berlin for the new application of imaging fluorescent peptides on Western blots....

INTEGRA announces how its VIAFLO 96 multichannel electronic pipette has been adopted by Neoteryx LLC as an integral part of a new high throughput biological sample collection and processing system. 

An increasing number of clinical labs are being confronted with a growing need to process more samples in parallel without jeopardizing the quality of their results. At a certain point it becomes impossible to keep up the pace using traditional multichannel pipettes...

ResistancePlus™ MG Test would bring disease and antibiotic resistance testing for potential “superbug”

ROMIL solvents are helping researchers at the Cavendish Laboratory, the University of Cambridge’s Department of Physics, to develop novel quantum dots which could be used in the next generation of solar panels.

James Xiao, a PhD student in the laboratory, explained: “We’re currently working on quantum dots which emit light in the infrared range, with the aim of significantly increasing the efficiency of photovoltaic cells.”....

The University of Dundee has been awarded £7.9 million by the Wellcome Trust for a joint project with GSK to boost efforts to find new drugs to treat some of the world’s most devastating parasitic diseases including visceral and cutaneous leishmaniasis, and Chagas’ disease.

These neglected diseases cause substantial suffering and an estimated 60,000 deaths annually world-wide. The funding will enable the established Dundee/GSK team to continue their work to develop novel drugs to treat these diseases over the next five years....

Research led by University of Leicester and University Hospitals of Leicester NHS Trust reveals ‘transformative outcomes’ for patients with chronic lymphocytic leukaemia

Scientists have described new results of a blood cancer study as ‘outstanding’ in tackling previously untreatable forms of chronic lymphocytic leukaemia (CLL). The advance led by a team from the University of Leicester and University Hospitals of Leicester NHS Trust, within the Hope Clinical Trials Facility...

Exclusive licence enables the development and commercialisation of 5hmC technologies for epigenetic biomarker discovery

Cambridge Epigenetix, a pioneer in the development and application of epigenetic technologies, today announced that it has entered into an exclusive license agreement with Boston Children’s Hospital giving access to leading-edge DNA profiling technologies...

The new £multi-million food and health research centre that will become the state-of-the-art home for the Quadram Institute is on schedule to be complete by mid-2018. 

As a first step to realising the ambition of the Quadram Institute, the Institute of Food Research (IFR) has realigned its science strategy to deliver to the vision of the new Institute. In preparation for the full opening of the Quadram Institute in 2018, IFR will transition into Quadram Institute Bioscience....

Leading autoclave and steriliser manufacturers, Astell Scientific, has a proud history dating back to 1884, but even they were slightly taken aback when Manchester brewers JW Lees asked them to replace their Astell laboratory autoclave: it was 30 years old!

JW Lees has been brewing since 1828 and produces a range of cask ales including CAMRA award-winning Moonraker dark ale, and limited edition seasonal cask ales, as well as lagers and smooth beers. The laboratory monitors the microbiology of the brewing process from wort to final packaging....

LGC Standards is delighted to announce that their agreement to distribute the National Measurement Institute of Australia (NMIA)’s reference materials (RMs) has been renewed, allowing customers continuing access to the NMIA’s expanding range of specialist RMs in four key areas: forensic drugs, sports drugs, pesticides and veterinary materials.

The NMIA is a world renowned National Measurement Institute (NMI). It has NATA accreditation for chemical reference materials production and is fully compliant with ISO Guide 34. In particular, the NMIA is a leading centre of expertise for sports drugs testing...

AMSBIO reports on an independent study that evaluated the use of CELLBANKER® and STEM CELLBANKER® reagents for cryopreservation and thawing of organoids.

Data is presented that clearly shows that liver organoids recovered and grew well in STEM-CELLBANKER®–GMP, CELLBANKER® 1 and CELLBANKER® 2 freezing media after being thawed out after 2 days and 4-days cryopreservation....

Merck has announced that BioInvent International AB, a Swedish company which develops novel immuno-regulatory antibodies to treat cancer, is upgrading and expanding its drug manufacturing facility with a full line of Merck’s Mobius^® single-use bioreactors.

BioInvent will add 3-, 50-, 200- and 1000-liter bioreactors to its upstream facility in Lund, Sweden, expanding capacity and improving flexibility and scalability....