AMSBIO reports on how several leading European research groups have used their Lipidure® coated microplates to help culture physiologically functional, light-responsive retinal organoids. Development of in vitro models of the human retina in which to perform pharmacological and toxicological studies is an urgent area of vital research. An essential step for developing in vitro models of human retina is the ability to generate laminated....
In a paper published in the American Chemical Society journal researchers from Bourgogne University showed that the use of superparamagnetic iron oxide nanoparticles (NPs) using multi modal – PET/MRI - showed promising improvements in imaging capabilities. Using an MR Solutions, cryogen free, 3T scanner with a PET clip on the sequential images were found to be highly beneficial providing high spatial resolution, high sensitivity....
SP Scientific has video interviewed Dr Kevin Ward of Biopharma Process Systems Ltd, to discuss the key benefits of the Lyostat5 Freeze-Drying Microscope (FDM), and how it can be used to generate critical formulation-specific data. Every freeze-drying formulation has a critical temperature, below which it should be maintained during primary drying in order to prevent processing defects....
A new type of drug that targets a genetic weakness in an untreatable childhood brain cancer could become the first ever treatment designed to target the disease. The prototype treatment could also offer hope for patients with the rare and devastating ‘stone man syndrome’ – in which muscles and ligaments turn to bone. Scientists at The Institute of Cancer Research, London, led research with an international team of colleagues....
Deben, a leading provider of in-situ testing stages together with innovative accessories and components for microscopy, reports on the study of snake fangs at Stellenbosch University. The university used the Deben CT500 in the process of analysing the internal and external morphology and mechanical properties of venomous snake fangs. The motivation behind the campaign was to understand in detail the internal and external morphology and mechanical properties of snake fangs....
new study, published in Science Translational Medicine, details the pioneering work undertaken by a collaboration led by Stephen Kingsmore, MD, DSc, President and CEO of Rady Children’s Institute for Genomic Medicine. The team, which includes British company Clinithink, utilized a machine learning process and clinical natural language processing to diagnose rare genetic diseases in record time....
Freeman Technology, a Micromeritics company, specialises in systems for measuring the flow properties of powders and has over 15 years’ experience in powder flow and powder characterisation. Expert teams provide comprehensive support alongside the company’s range of products. Systems are installed around the world across a diverse range of industries....
Dolomite Bio’s Nadia Instrument is helping researchers to gain a deeper understanding of motor neuron disease through the use of single nuclei RNA sequencing (sNuc-Seq).This automated, microfluidic droplet-based platform allows flexible encapsulation of up to eight samples in parallel in under 20 minutes, helping to accelerate studies and generate high quality data. Christopher Sibley, a Junior Research Fellow in the Brain Science Division at Imperial College London...
Testa Analytical Solutions e.K reports that its BI-XDC X-Ray Disc Centrifuge is enabling scientists to make accurate, high resolution particle size distribution measurements, from nanometres to tens of micrometres, without time consuming calibration or absorption correction. Based on the principle of photosedimentation, the BI-XDC measures the size of particles according to the time the particle takes to sediment in...
Postnova Analytics Inc. reports how its Electrical Asymmetrical Flow Field Flow Fractionation (EAF4) and Size Exclusion Chromatography (SEC) modules have been used to determine the physicochemical and biophysical attributes of monoclonal antibodies. EAF4 technology uniquely combines the principle of Electrical and Asymmetrical Field Flow Fractionation in just one system....
Wildcat Laboratory Solutions reports on their recent installation of a custom designed Biological Safety Cabinet at Eligo Bioscience - a biotech start-up in Paris, France. Erica Lieberman - Head of Discovery and Automation at Eligo Biosciences commented “We needed to put our liquid-handling robot inside a biological safety cabinet so that it could be used for high-throughput screening of drug candidates against pathogenic bacterial strains....
Deben, a leading provider of in-situ testing stages together with innovative accessories and components for microscopy, reports on how University of Ghent have used the Deben CT5000 to study the Uniaxial Compressive Strength of four different depositional limestones. Sourced from the Paris Basin these limestones are often used as building material in France and Belgium. The University’s work was performed using HECTOR µCT partnered with...
The collaboration provides StarDrop™ users with easy access to ICSYNTHlight, an entry-level version of InfoChem’s computer-aided synthesis design (CASD) software to generate synthesis pathways for a target molecule. By stimulating new and unbiased ideas, researchers can explore alternative or novel synthetic routes with the potential to save time and reduce costs...
“The world of microwave synthesis”is a website addressed to experienced microwave chemists as well as chemists who are new to the field of microwave synthesis. Visitors to the website benefit from highly useful tools, such as an application database including more than 1000 chemical reactions which have been successfully performed in Anton Paar synthesis reactors....
Researchers at TauRx Therapeutics are using the automation capabilities of the Syrris Atlas HD reactor systems to simplify and accelerate process development for its product pipeline. Based at the company’s primary research facilities at the University of Aberdeen, Scotland, the Syrris equipment is an integral part of the quality by design (QBD) process optimization workflow....
Evotec AG and The Global Antibiotic Research and Development Partnership announce the formation of a new strategic public-private partnership to tackle the growing threat of antimicrobial resistance. By joining forces, Evotec and GARDP will leverage their capabilities and networks to address drug-resistant bacterial infections. This includes bringing together GARDP's clinical expertise and...
Interactive Software is working with UKCRC Tissue Directory and Coordination Centre to connect UK Biobanks and help them achieve their aim of assisting researchers by simplifying the sourcing of biological samples. The centralised tissue directory will also help raise the profile of Biobanks and ensure donated samples are visible and used for the purpose for which they were collected....
The Chromatographic Society and Separation Science Group of the Royal Society of Chemistry are pleased to announce “Emerging Separations Technologies 2019”. This one day meeting will be held at RSC Burlington House, London, UK where a full symposium program will be run alongside a vendor exhibition, opportunity to network and lunch provided by the excellent Burlington House team. The agenda will cover a range of highly pertinent topics...
Project to focus on data-driven cell conversions to produce cell therapies with potential application in wound healing, and oncology immunotherapy. Cell Mogrify Ltd, a UK company aiming to transform the future development of cell therapies, today announced that it has been awarded $555,000 USD (£420,000 GBP) funding from Innovate UK,the UK’s innovation agency, through the investment accelerator for innovation in precision medicine....
Accelerated Technology Laboratories, Inc. (ATL), continues the 2019 LIMS Webcast Series with 'A Practical Guide to Selecting the Right LIMS'. This webcast is targeted at laboratories who are planning to implement a new LIMS, either for the first time or as a replacement for an existing system. Where do you start and what evaluation factors are most important?....
The University of Manchester, and Owlstone Medical,a global diagnostics company developing a breathalyzer for applications in early disease detection and precision medicine, today announce the award of an Asthma UK/Innovate UK grant for theimprovement of asthma diagnosis. Under a joint Asthma UK and Innovate UK funding initiative, which seeks to broker research collaborations between academia and UK industry to develop new tools that can...
The Videometerlab4 Multispectral Imaging System from Analytik now makes it possible to scan crop samples for Fusarium infection in under 10 seconds. The analytical methodology employed does not require traditional time-consuming sample preparation and eliminates the need for chemicals and costly consumables. Fusarium is a fungal disease which commonly affects wheat, barley, oats, triticale and grasses as seeds, seedlings and adult plants. The range of symptoms caused by...