Testa Analytical Solutions e.K reports on how its NanoBrook Omni particle size analyser and BI-ZTU autotitrator can be used together to detect the onset of aggregation in nanoparticles.

The NanoBrook Omni instrument offers a single powerful and accurate solution for particle sizing and zeta potential analysis. The instrument allows users to measure samples in nearly every possible suspension environment from high salts such as PBS and sea water to organic solvents and aqueous solutions. The instrument offers unmatched particle sizing, with the highest sensitivity, utilizing three light scattering measurement angles for truly unbiased measurement results. The BI-ZTU autotitrator option for the NanoBrook Omni provides an ideal solution for automated measurement of particle size as a function of pH.

Applications that use iron oxide nanoparticles are vast and growing due to its stability, low toxicity, and magnetic properties. Given the great potential for applications using iron oxide, it is highly desirable to understand the effect of chemical changes to the surface of the nanoparticle.

Aggregation of nanoparticles can occur due to changes in pH or temperature. In a newapplications report*researchers show how Dynamic light Scattering (DLS) offers a quick and easy way of determining the effective diameter (or size) of iron oxide nanoparticles and an autotitrator can help automate the process of detecting changes in particle size as a function of pH. They conclude that the NanoBrook Omni particle size analyser and BI-ZTU autotitrator provide a highly effective instrumental solution for the detection on aggregation of nanoparticles due to changes in pH.

Testa Analytical Solutions e.K. is a company dedicated to supplying the best possible instrumental solutions for characterization of polymers, particles, nanomaterials and proteins. Drawing upon over 30 years’ experience of technologies serving these markets, the staff at Testa Analytical are happy to share their knowledge with researchers worldwide to help provide them with a working solution for even the most demanding applications.

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