Vapourtec has developed the Peptide-Builder, a fully automated, high throughput, benchtop peptide synthesiser, which was launched at the recent TIDES Europe event in Hamburg. Incorporating Vapourtec’s disruptive Variable Bed Flow Reactor (VBFR) technology, it dramatically improves cycle efficiency and reduces solvent consumption. Based on customer feedback, the Peptide-Builder is designed to be the smallest high throughput synthesiser available...
Vapourtec’s recently launched, pioneering eBPR is an innovative, self-contained, electronically adjustable back pressure regulator that does not require any external reference gas pressure. Back pressure regulators (BPR) have, until now, been fixed and manually or electronically adjustable through the external control of gas pressure. Vapourtec MD Duncan Guthrie explained: “A BPR is a critical part of any flow chemistry system...
Flow chemistry engineering specialist Vapourtec is investing in the future of flow chemistry through a partnership with the organic chemistry team at the University of Bristol’s Centre for Doctoral Training (CDT), headed up by Professor Varinder K Aggarwal. Over the next five years a minimum of 70 PhD candidates will have access to Vapourtec’s R-Series and E-Series flow chemistry systems in the first year of their doctorates as part of a scheme that is supported by the Engineering and Physical Sciences Research Council (EPSRC)...
Vapourtec has dramatically increased the capabilities of its E-Series flow chemistry system with the introduction of optional, user interface software. The new software has been developed with customer feedback and utilises intuitive touchscreen technology. It allows fully automated reactions to run unattended and provides the foundation for automated reaction optimisation...
Vapourtec has launched the Peptide-ExplorerLT aimed at chemists looking to explore and optimise linear peptide synthesis. The new system, which produces the same high-quality peptides as Vapourtec’s existing Peptide-Explorer launched in 2020, features a more compact footprint and is available at a lower price point. Vapourtec CSO Dr. Manuel Nuño explained: “Peptide chemists can now access all the benefits of Fast Flow Solid Phase Peptide Synthesis (FF-SPPS) at a price that is comparable with traditional, automated batch synthesisers...
Vapourtec and Accelerated Materials working together to develop the scope and potential of flow chemistry. Flow chemistry engineering specialists Vapourtec is working with Accelerated Materials to develop the scope and potential of machine learning (ML) in flow chemistry. Machine learning delivers a number of benefits for chemical optimisation including enhancing the efficiency and accuracy of predictive modelling...
Vapourtec’s pioneering UV-150 photochemical reactor has been enhanced with a number of significant improvements. Launched in 2014, the UV-150 was the first commercially available continuous process photochemistry reactor available for the research and development market and has, since then, been cited in over 60 peer review chemistry publications and has seen broad applications...
Flow chemistry engineering specialists Vapourtec have strengthened their presence across Europe with the signing of a distribution deal with Belgium-based Analis. Analis Sales and Marketing Manager Ken De Roover commented: “We are delighted to strengthen our chemical synthesis portfolio with Vapourtec and will be distributing their full range of flow...
After months in development flow chemistry engineering specialists Vapourtec have provided a prototype electrochemical reactor to Dr Thomas Wirth, Professor of Organic Chemistry at Cardiff University, for evaluation. The latest prototype offers a range of exciting features that will be implemented in the production versions including temperature control and operation...
Flow chemistry engineering specialists Vapourtec have been engaged in a successful collaboration with Cambridge-based New Path Molecular Research Ltd (NPM) over the past year, focusing on the development of new reactor technology and methods for peptide synthesis.
The collaboration has focused on the development of continuous flow technologies to reduce wastage and implement in-process controls in solid phase peptide synthesis (SPPS). Benefits delivered so far by the partnership include the real-time, in-process monitoring of coupling efficiency....
Flow chemistry specialists Vapourtec (Cambridge, UK) have launched the SF-10 laboratory reagent pump offering both precision and versatility and opening up a broad range of important applications within biology and chemistry labs worldwide.
Intended for general laboratory use, the SF-10 is a highly chemically resistant peristaltic pump capable of delivering smooth flow at up to 10 bar pressure. Operating modes covered include; constant flow rate, ramping flow rate, volume dosing, pressure controller and gas delivery. The versatility of the SF-10 has opened up a host of uses including precise reagent delivery into batch reactors, control of gas delivery....
Interest in flow chemistry systems has doubled since 2010 according to UK-based flow chemistry engineering specialists Vapourtec (Cambridge, UK) who experienced a further 15% increase in turnover in 2015.
Vapourtec's turnover over the past 5 years has increased by 100% mirroring key industry reports that reveal an ever growing interest and engagement by chemists around the world in continuous process technology. Vapourtec founder and MD Duncan Guthrie commented: "We've experienced another rapid year of growth and this reflects growing awareness of the benefits and the impressive economies of scale that can be delivered by flow chemistry...
Flow chemistry engineering firm Vapourtec (Cambridge, UK) has unveiled a new look website that includes a host of features, exclusive resources and information aimed at chemists across all sectors and industries.
The updated online presence incorporates a member-based Knowledge Base resource, abstracts of over 180 published papers, 42 application notes and detailed data on the performance of Vapourtec's array of flow chemistry systems and component parts. Duncan Guthrie, founder and MD of Vapourtec, commented: "This has been a longstanding project to create a website that offers a wealth of invaluable flow chemistry information...
Specialist flow chemistry firm Vapourtec (Cambridge, UK) has launched a reactor housing for micromixer reactors that complements its existing standard, cooled, heated and photochemical family of reactors.
Vapourtec’s new micromixer, which plugs easily into ports within their current flow chemistry systems, features chip reactors housed within a glass and PTFE manifold that offers a clear visibility of the reactants. A range of seven different glass micromixer reactor chips has been developed for use with the new reactor housing. Cooled gas is circulated around the micromixer chips, using Vapourtec’s cooling module, to deliver temperatures as low as -40º C. Heated air, reaching temperatures up to 150º C...
Vapourtec have announced a research collaboration with Professor Pengfei Li of the Frontier Institute of Science and Technology (FIST) at Xi'an Jiaotong University in China to develop novel, continuous flow, photochemical reactions using Vapourtec's easy-Photochem reactor system.
The partnership will involve photochemical techniques for the synthesis of novel bioactive molecules and will include both direct and photo-catalysed photochemical reactions. An example of Professor Li's previous work in this area involves a visible light-induced singlet oxidative dearomatization as documented in the following published article: 'Stereocontrolled Construction of the Tricyclic Framework of Tiglianes and Daphnanes by an Oxidative...
One of the many key features of Vapourtec’s (Suffolk, UK) recently launched UV-150 Photochemical Reactor is the patented Dichroic Mirror that allows for better temperature control during continuous process photochemistry experiments.
The mirror’s reflective coating allows for the efficient absorption and despatch of heat in terms of infrared wavelengths whilst reflecting ultraviolet wavelengths back into the reaction. Andrew Mansfield of Vapourtec explained: “The UV-150 is already making its mark in the field of photochemistry with both academic groups and the pharmaceutical industry finding that it delivers levels of control, scalability and consistency that was previously unavailable...
One of the many key features of Vapourtec’s (Suffolk, UK) recently launched UV-150 Photochemical Reactor is the patented Dichroic Mirror that allows for better temperature control during continuous process photochemistry experiments.
The mirror’s reflective coating allows for the efficient absorption and despatch of heat in terms of infrared wavelengths whilst reflecting ultraviolet wavelengths back into the reaction. Andrew Mansfield of Vapourtec explained: “The UV-150 is already making its mark in the field of photochemistry with both academic groups and the pharmaceutical industry finding that it delivers levels of control, scalability and consistency that was previously unavailable...
Two of the world’s leading flow chemistry systems as well as the latest addition to the field of photochemistry technology will be on show at Chemspec Europe on 18-19 June and IMRET (Conference on Microreaction Technology) 23-25 June.
Both events take place in Budapest, Hungary. Manufactured by UK firm Vapourtec, the E-Series and R-Series continuous process technologies are already established as pioneering systems within flow chemistry and the UV-150 photochemical reactor, launched earlier this year, is making its mark with those interested in photochemistry. Vapourtec founder and MD Duncan Guthrie explained: “Chemspec Europe and IMRET are prime opportunities for chemists across the globe to uncover...
Chemistry engineering specialists Vapourtec (Suffolk, UK) has reached the notable landmark of appearing in 125 peer reviewed publications, making it the clear global leader in terms of research breakthroughs and published findings for flow chemistry systems.
Vapourtec systems have been used in some notable published breakthroughs including the recent research from a leading academic group headed by Professor Steven V Ley at the University of Cambridge’s Department of Chemistry into more efficient production methods for breast cancer drug Tamoxifen utilised Vapourtec’s E-Series system. Also in 2012 the Innovative flow manufacturing route for Artemisinin, a drug that addresses Malaria, was published by Professor Peter Seeberger of the Max Planck Institute, Berlin....
Chemistry engineering specialists Vapourtec (Suffolk, UK) has seen its flagship R-Series flow chemistry system reach a notable milestone with global sales recently reaching the 200 mark.
The R-Series has a wide range of applications and is already used around the world by many major companies including BP, Pfizer, GSK, Sanofi, Novartis and Johnson & Johnson. The 200th system was purchased by the University of Manitoba, based at Winnipeg in Canada. Assistant Professor Geoff Tranmer PhD from their Faculty of Pharmacy is no stranger to Vapourtec’s technology having first used the R-Series system whilst at CambridgeUniversity in 2006....
Vapourtec (Suffolk, UK) has developed the UV-150, a pioneering photochemical reactor that will lead to more efficient, precise, consistent, safe and scalable photochemical synthesis offering potential routes for novel compounds and building blocks together with possible new manufacturing processes. Two years in development, the plug and play reactor offers a wide range of features that makes it an industry first. With no intensive set up required, it is unique within the field of flow chemistry and is designed to complement Vapourtec’s existing R-Series and E-Series flow chemistry systems used in hundreds of laboratories around the world...
The patented Cooled Reactor system, developed by Vapourtec (Suffolk, UK) and launched in 2010, is continuing to play a key role in major flow chemistry research breakthroughs.
Recently cited in an important research paper “Continuous flow-processing of organometallic reagents using an advanced peristaltic pumping system and the telescoped flow synthesis of (E/Z)-Tamoxifen” by the Group of Prof Steven V. Ley, Department of Chemistry, University of Cambridge (UK), the system contributes to a more efficient manufacturing process for Breast Cancer drug Tamoxifen....
A recent academic paper published in the journal Organic Process Research and Development by the Group of Prof Steven V. Ley, Department of Chemistry, University of Cambridge (UK) outlines a possible breakthrough for the manufacture of breast cancer drug Tamoxifen involving flow chemistry technology developed by UK specialist chemical engineering firm Vapourtec.
A prominent feature in the success of the research carried out, profiled in the article “Continuous flow-processing of organometallic reagents using an advanced peristaltic pumping system and the telescoped flow synthesis of (E/Z)-tamoxifen”, was the use of Vapourtec’s E-Series flow chemistry system that enables the processing of organometallic reagents....
Suffolk (UK) based Vapourtec has partnered up with Dr Nicholas Leadbeater and the New Synthetic Methods Group at the University of Connecticut (USA) to produce a new guide entitled “An Introduction to Flow Chemistry – A Practical Laboratory Course”.
Aimed principally at undergraduate teaching laboratories within colleges and universities but also a great asset to the research lab, the 100 page manual details a set of ten continuous-flow processing experiments, each of which can be easily delivered in conjunction with Vapourtec’s E-series flow unit during a regular lab period. Dr Leadbeater, Associate Professor at the University of Connecticut and widely recognised as one of the leading lights in the fields of flow chemistry and new educational initiatives, commented: “Flow chemistry offers a lot of exciting possibilities in terms of running reactions for a wide variety of industries and it’s vital that it is encouraged and nurtured in the field of education...
A major award from the Canada Foundation for Innovation to Professor André B. Charette allowed the Department of Chemistry at the Université de Montréal to take delivery of 5 Vapourtec R-Series systems, taking the total number installed to 6
The systems are equipped for the full range of reaction types (high temperature, cryogenic, homogeneous and heterogeneous), with advanced Flow CommanderTMcontrol software for maximum productivity, efficient Design of Experiments and reliable data recording.The department is one of the member institutions of the Centre in Green Chemistry and Catalysis, (a consortium drawing members from all the major Quebec universities) which provides analytical and synthesis services to the whole scientific community in Quebec...
Vapourtec has developed the Peptide-Builder, a fully automated, high throughput, benchtop peptide synthesiser, which was launched at the recent TIDES Europe event in Hamburg. Incorporating Vapourtec’s disruptive Variable Bed Flow Reactor (VBFR) technology, it dramatically improves cycle efficiency and reduces solvent consumption. Based on customer feedback, the Peptide-Builder is designed to be the smallest high throughput synthesiser available...
Vapourtec’s recently launched, pioneering eBPR is an innovative, self-contained, electronically adjustable back pressure regulator that does not require any external reference gas pressure. Back pressure regulators (BPR) have, until now, been fixed and manually or electronically adjustable through the external control of gas pressure. Vapourtec MD Duncan Guthrie explained: “A BPR is a critical part of any flow chemistry system...
Flow chemistry engineering specialist Vapourtec is investing in the future of flow chemistry through a partnership with the organic chemistry team at the University of Bristol’s Centre for Doctoral Training (CDT), headed up by Professor Varinder K Aggarwal. Over the next five years a minimum of 70 PhD candidates will have access to Vapourtec’s R-Series and E-Series flow chemistry systems in the first year of their doctorates as part of a scheme that is supported by the Engineering and Physical Sciences Research Council (EPSRC)...
Vapourtec has dramatically increased the capabilities of its E-Series flow chemistry system with the introduction of optional, user interface software. The new software has been developed with customer feedback and utilises intuitive touchscreen technology. It allows fully automated reactions to run unattended and provides the foundation for automated reaction optimisation...
Vapourtec has launched the Peptide-ExplorerLT aimed at chemists looking to explore and optimise linear peptide synthesis. The new system, which produces the same high-quality peptides as Vapourtec’s existing Peptide-Explorer launched in 2020, features a more compact footprint and is available at a lower price point. Vapourtec CSO Dr. Manuel Nuño explained: “Peptide chemists can now access all the benefits of Fast Flow Solid Phase Peptide Synthesis (FF-SPPS) at a price that is comparable with traditional, automated batch synthesisers...
Vapourtec and Accelerated Materials working together to develop the scope and potential of flow chemistry. Flow chemistry engineering specialists Vapourtec is working with Accelerated Materials to develop the scope and potential of machine learning (ML) in flow chemistry. Machine learning delivers a number of benefits for chemical optimisation including enhancing the efficiency and accuracy of predictive modelling...
Vapourtec’s pioneering UV-150 photochemical reactor has been enhanced with a number of significant improvements. Launched in 2014, the UV-150 was the first commercially available continuous process photochemistry reactor available for the research and development market and has, since then, been cited in over 60 peer review chemistry publications and has seen broad applications...
Flow chemistry engineering specialists Vapourtec have strengthened their presence across Europe with the signing of a distribution deal with Belgium-based Analis. Analis Sales and Marketing Manager Ken De Roover commented: “We are delighted to strengthen our chemical synthesis portfolio with Vapourtec and will be distributing their full range of flow...
After months in development flow chemistry engineering specialists Vapourtec have provided a prototype electrochemical reactor to Dr Thomas Wirth, Professor of Organic Chemistry at Cardiff University, for evaluation. The latest prototype offers a range of exciting features that will be implemented in the production versions including temperature control and operation...
The collaboration has focused on the development of continuous flow technologies to reduce wastage and implement in-process controls in solid phase peptide synthesis (SPPS). Benefits delivered so far by the partnership include the real-time, in-process monitoring of coupling efficiency....
Intended for general laboratory use, the SF-10 is a highly chemically resistant peristaltic pump capable of delivering smooth flow at up to 10 bar pressure. Operating modes covered include; constant flow rate, ramping flow rate, volume dosing, pressure controller and gas delivery. The versatility of the SF-10 has opened up a host of uses including precise reagent delivery into batch reactors, control of gas delivery....
Vapourtec's turnover over the past 5 years has increased by 100% mirroring key industry reports that reveal an ever growing interest and engagement by chemists around the world in continuous process technology. Vapourtec founder and MD Duncan Guthrie commented: "We've experienced another rapid year of growth and this reflects growing awareness of the benefits and the impressive economies of scale that can be delivered by flow chemistry...
The updated online presence incorporates a member-based 
Vapourtec’s new micromixer, which plugs easily into ports within their current flow chemistry systems, features chip reactors housed within a glass and PTFE manifold that offers a clear visibility of the reactants. A range of seven different glass micromixer reactor chips has been developed for use with the new reactor housing. Cooled gas is circulated around the micromixer chips, using Vapourtec’s cooling module, to deliver temperatures as low as -40º C. Heated air, reaching temperatures up to 150º C...
The partnership will involve photochemical techniques for the synthesis of novel bioactive molecules and will include both direct and photo-catalysed photochemical reactions. An example of Professor Li's previous work in this area involves a visible light-induced singlet oxidative dearomatization as documented in the following published article: 'Stereocontrolled Construction of the Tricyclic Framework of Tiglianes and Daphnanes by an Oxidative...
The mirror’s reflective coating allows for the efficient absorption and despatch of heat in terms of infrared wavelengths whilst reflecting ultraviolet wavelengths back into the reaction. Andrew Mansfield of Vapourtec explained: “The UV-150 is already making its mark in the field of photochemistry with both academic groups and the pharmaceutical industry finding that it delivers levels of control, scalability and consistency that was previously unavailable...
The mirror’s reflective coating allows for the efficient absorption and despatch of heat in terms of infrared wavelengths whilst reflecting ultraviolet wavelengths back into the reaction. Andrew Mansfield of Vapourtec explained: “The UV-150 is already making its mark in the field of photochemistry with both academic groups and the pharmaceutical industry finding that it delivers levels of control, scalability and consistency that was previously unavailable...
Both events take place in Budapest, Hungary. Manufactured by UK firm Vapourtec, the E-Series and R-Series continuous process technologies are already established as pioneering systems within flow chemistry and the UV-150 photochemical reactor, launched earlier this year, is making its mark with those interested in photochemistry. Vapourtec founder and MD Duncan Guthrie explained: “Chemspec Europe and IMRET are prime opportunities for chemists across the globe to uncover...
Vapourtec (Suffolk, UK) has developed the UV-150, a pioneering photochemical reactor that will lead to more efficient, precise, consistent, safe and scalable photochemical synthesis offering potential routes for novel compounds and building blocks together with possible new manufacturing processes. Two years in development, the plug and play reactor offers a wide range of features that makes it an industry first. 
The systems are equipped for the full range of reaction types (high temperature, cryogenic, homogeneous and heterogeneous), with advanced Flow CommanderTMcontrol software for maximum productivity, efficient Design of Experiments and reliable data recording.The department is one of the member institutions of the Centre in Green Chemistry and Catalysis, (a consortium drawing members from all the major Quebec universities) which provides analytical and synthesis services to the whole scientific community in Quebec...