Search News Archives
Follow us on
Conferences | Events
Lab Bulletin Media Partners
Malvern Instruments Ltd

Malvern Instruments Ltd

Malvern Instruments Ltd

Products

Contact Malvern Instruments Ltd


If you have not logged into the website then please enter your details below.

All articles from Malvern Instruments Ltd

  The Future of Particle Characterization

malvernThe live launch of Malvern Panalytical's Morphologi 4 and Morphologi 4-ID. February 14th 2 PM GMT / 9 AM EST. Be the first to learn about the new Morphologi 4 Range of automated static imaging systems - designed to help you understand and optimize your processes and particulate samples by delivering robust and reproducible insight into particle size, shape and chemical ID...

 

  Malvern Launches MicroCal PEAQ-DSC for Faster, more Accurate Characterization of Protein and Biomolecule Stability

The new MicroCal PEAQ-DSC microcalorimeter from Malvern Instruments resets the performance standard for characterizing protein and biomolecule stability.

MicroCal PEAQ DSCThis latest innovation in Differential Scanning Calorimetry (DSC) has been created specifically for the regulated environment and delivers essential data to guide biopharmaceutical development, from protein engineering, through pre-formulation and process development, to formulation and manufacture of the final product. The new system offers developers a quick stability assay to identify biotherapeutics with good stability potential and enables them to determine...

 

  Calorimetry and Collaboration

Leading Industry Experts Gather for Malvern MicroCal Open Forum Meetings in Europe and the US

Malvern MicroCal scientistsLeading microcalorimetry experts from across the globe will be joining Malvern MicroCal scientists at open forum meetings in Europe and the USA that provide a valuable opportunity for scientists to extend their understanding and application of this powerful analytical technique. Microcalorimetry enables detailed investigation of the interactions between and thermodynamics of molecules/biomolecules...

 

  The New Zetasizer AT – Automated Online Nanoparticle Sizing for Process Monitoring

Malvern Instruments has launched the new Zetasizer AT, a robust, online, automated analyzer that uses dynamic light scattering (DLS) to automatically measure the size of nanoparticles in suspensions and emulsions.

Zetasizer ATThe new analyzer provides timely and reliable data that enables tracking of processes in the sub-micron size range, such as emulsification, dispersion, milling and homogenization, while at the same time eliminating the delays and inefficiencies associated with manual analysis....

 

  New Research Highlights Efficient in Vitro Strategies for Demonstrating Bioequivalence in Generic Nasal Sprays

Experts from Nanopharm, supported by Malvern instruments and with funding from the Food and Drug Administration (FDA), have carried out experimental studies to identify analytical strategies that can help bring generic nasal sprays to market faster.  

malvernThe findings, presented at Respiratory Drug Delivery (RDD) 2016, describe the benefits of applying component-specific particle size measurement and rheological characterization to determine the Critical Material and Process Attributes of suspension nasal sprays.  By supporting fast and robust bioequivalence testing, these techniques add value in the development of abbreviated new drug applications...

 

  NanoChOp Project Highlights Value of NanoSight for Monitoring Nanoparticle Characteristics in Biological Systems

Researchers working on the European Metrology Research Project NanoChOp (Chemical and Optical Characterization of Nanomaterials in Biological Systems), funded by EURAMET, have concluded that the NanoSight Nanoparticle Tracking Analysis system from Malvern Instruments offers unique insight into the behavior of nanoparticles in biological systems.

NanoSight Nanoparticle Tracking Analysis system from Malvern Such insight supports ongoing efforts to assess the potential risks to human health posed by the increasing use of nanomaterials. Dorota Bartczak, Researcher in Inorganic Analysis at LGC commented that ”Measurement methods and techniques that provide reliable data for researchers to understand how nanoparticles behave in complex biological systems are crucial for the human risks assessments needed to ensure that the...

 

  ‘Unlocking New Areas of Disease Research’: Researchers at the University of Alabama use NanoSight from Malvern to Understand the Role of Exosomes in Disease Transmission

Data measured using the NanoSight NS300 from Malvern Instruments is providing new insights into the role of exosomes in diseases such as cancer, arthritis, Alzheimer’s disease and cystic fibrosis, in pioneering research at the University of Alabama - Birmingham (UAB).

NanoSight from Malvern“Early research on exosomes, or extracellular vesicles, focused on their role in excreting unwanted waste from cells,” said Shawn Williams, facility manager and imaging specialist. “However, we’re now starting to understand their wider functionality in intercellular communication and the transmission of disease. The NanoSight system is playing a central role in helping us advance in this new and exciting area of research, by...

 

  New research from Clausthal University Highlights the Value of Malvern’s Kinexus for Characterizing Drilling Fluids

Researchers at The Institute of Petroleum Engineering at TU Clausthal in Germany are being supported by Malvern Instruments in new work to understand and optimize the performance of Enhanced Oil Recovery (EOR) fluids.

Kinexus rheometer from MalvernThe polymeric solutions used for EOR exemplify the fluids used in a range of drilling applications to maximize oil extraction while at the same time safeguarding geological formations. Details of the work have recently been presented in a new webinar which is available for download/viewing. EOR involves injecting a solution into the porous rock surrounding a well and can boost the amount of oil extracted by up to 20%...

 

  New Software; Growing Team: Two Years on NanoSight is Reaping the Benefits of Joining Malvern Instruments

The latest software release along with an expansion of the global technical specialist team, highlight Malvern Instruments’ ongoing commitment to extending and supporting the application of NanoSight, a nanoparticle characterization technology with unique capabilities.

Nanoparticle Tracking AnalysisThe Malvern NanoSight range enables the visualization, sizing and counting of nanoparticles, exosomes, protein aggregates, and is increasingly being used in biopharma and nanoparticle research. “Two years on from joining Malvern, the benefits of becoming part of a larger global business are clear. NanoSight customers are now benefiting directly from Malvern’s highly developed skills in making complex analytical techniques more...

 

  What is it, and Where Did it Come From?: Malvern/Bio-Rad Collaboration Makes Particle Identification Quicker and Easier

A collaboration between Malvern Instruments (Malvern, UK) and Bio-Rad (Hercules, California) has delivered new analytical tools for the rapid identification of unknown particles.

MalvernNew software to support Malvern’s Morphologi G3-ID, which analyzes particle size, shape and chemical composition, enables the direct comparison of measured Raman spectra with reference spectra in the extensive database of Bio-Rad’s market-leading KnowItAll¼ software. The result is powerful, robust particle identification capabilities for scientists working in forensic analysis and pharmaceutical/biopharmaceutical development who are...

 

  Smarter Particle Sizing, Better Refreshment! Malvern Launches New Accessories for Chocolate and Coffee Analysis

Malvern Instruments have released new accessories for the Mastersizer3000 which optimize  the particle size analysis of chocolate and coffee.

Mastersizer3000The two new, innovative additions to the Mastersizer portfolio – Chocosizer and the Funnel Sample Feeder for the Aero S - enable faster analysis and make it easier to develop and apply the robust particle sizing methods that are essential to both industries. Particle size directly impacts both the flavor and strength of coffee. Consistent production of the correct grade of coffee therefore relies heavily on the quick and reproducible...

 

  Resolve Challenges, Find Solutions: Join Malvern for Expert Help on Protein Interaction Analysis with MicroCal PEAQ-ITC

At the 29th Annual Symposium of The Protein Society (22-25th July, Barcelona, Spain) Natalia Markova, Principal Scientist- MicroCal, Malvern Instruments, will be presenting a workshop on how to enable high resolution protein interaction analysis using the latest MicroCal PEAQ-ITC system. 

/MicroCal PEAQ-ITC systemStudies of biomolecular interactions are fundamentally important in all areas of the life sciences since such interactions drive and regulate all biological processes. To register for the workshop which will include a complimentary lunch please go to: http://www.malvern.com/protein2015. The workshop will address current challenges scientists face in interaction analysis through a Q&A panel session with calorimetry experts. A subsequent...

 

  Expert Presentations and Practical Demonstrations Impress Nanoparticle Characterization Seminar Attendees

A series of highly interactive 2-day seminars delivered by Malvern Instruments, which encompassed expert presentations and ‘up close’ practical workshops showcasing the latest in nanoparticle characterization technology, have been widely praised by attendees.

nanoparticlesFeedback from delegates to the ‘Latest Methods in Nanoparticle Characterization’ events, which took place in various locations across the USA, Canada, Mexico and Brazil from April through to June, confirmed especially an appreciation of the detailed presentations about different characterization technologies and their applications, and the value of being able to participate in live instrument demonstrations. The seminars were presented as part...

 

  Viscosizer TD: A New Automated Tool for Biophysical Characterization

Malvern Instruments has launched a new system based around Taylor Dispersion Analysis (TDA) to provide researchers with a novel orthogonal technique to accelerate biopharmaceutical drug candidates through the development pipeline.

Viscosizer TDThe Viscosizer TD speeds up stability and formulation studies by offering unique solution-based molecular sizing capabilities, combined with relative viscosity measurement. Ultra-low sample volumes, fully automated measurement protocols, and precise environmental control for sample storage and measurement further enhance the value of the new system for early developability screening. TDA is a microcapillary flow-based technique that...

 

  A Dynamic Approach to Educating Industry-Ready Nanotechnology Technicians

Seattle’s Hub for Industry-Driven Nanotechnology Education (Seattle, USA), an imaginative educational body with a flexible and highly productive model for nanotechnician training, has identified dynamic light scattering particle sizing as an essential analytical technique, investing in a Zetasizer Nano from Malvern Instruments.

SHINE“At SHINE we train the next generation of technicians to directly meet the needs of the nanotechnology industries in the Pacific North West,” said Peter Kazarinoff, Managing Director of SHINE. “A vital part of this is giving our students access to the analytical techniques and systems that they will use when employed.  The simplest reason we chose a Zetasizer Nano is that it is the instrument most widely used for nanoparticle and protein size...

 

  Solving the Problem of Lignin Characterization - Malvern Presents Proven Strategies for Successful GPC/SEC Analysis

Chromatography specialists from Malvern Instruments will present a reliable optimized solution for lignin characterization at a series of upcoming conferences in 2015, the first of which is Nordic Polymer Days, Denmark, June 1 – 3.

 Malvern InstrumentsLignin is a vital industrial polymer but presents significant challenges when it comes to measurement of the properties that define its performance. Through experimental study Malvern has identified the best strategy to apply when using gel permeation/size exclusion chromatography (GPC/SEC) to secure reliable information. The results of this work will also be presented at the 13th Annual UNESCO/IUPAC Conference on...

 

  New OMNISEC from Malvern Instruments Brings Unmatched Performance in the Analysis of Synthetic Polymers

The unrivalled performance of OMNISEC, Malvern Instruments’ new gel permeation chromatography/size exclusion chromatography (GPC/SEC) system, is demonstrated in a series of recently released application notes which highlight the sensitivity of the system in synthetic polymer analysis. 

OMNISEC RESOLVEThe OMNISEC platform brings together highly efficient and precise sample separation in the OMNISEC RESOLVE module with a fully integrated, high sensitivity multi-detector array in the OMNISEC REVEAL module. A complete OMNISEC system delivers the accurate molecular weight and molecular size measurements and detailed structural information needed to drive synthetic polymer research. The polymer industry is actively engaged in developing...

 

  Second edition of popular nanoparticle characterization book adds more research reviews

A brand new online edition of a highly popular book that reviews third party papers on the applications and usage of Nanoparticle Tracking Analysis (NTA) is now available from Malvern Instruments.

Updated for 2015 this latest edition reviews the first 1000 reports of the applications and usage of NTA and supersedes the original 2013 publication. The book is intended to enable readers to keep abreast of work being done in a variety of different fields and to provide Malvern NanoSight NTA users with insight into the work of others who are using the technology.

 

  Malvern to Showcase New Products for Life Science and Industry at ACHEMA 2015

Malvern Instruments will showcase their expanding range of products for the life science and industrial sectors at ACHEMA 2015.

 MicroCal The four-day event (15-19 June) being held in Frankfurt, Germany will be the first major European outing for the latest additions to Malvern’s recently acquired MicroCal microcalorimetry range and for the innovative OMNISEC GPC/SEC platform. Visit the Malvern stand in Hall 4.1, stand number D59. Malvern’s products for life scientists provide information to drive drug discovery and development. Center stage will be the recently...

 

  Malvern Zetasizer Nano Supports Advances in Carbon Nanotube Synthesis

New research from the University of Padova in Italy shows how the Zetasizer Nano S, a nanomaterial and molecular characterization system from Malvern Instruments, is supporting the development of soluble carbon nanotubes (CNTs).

Zetasizer Nano SCNTs exhibit unique electronic, optical, mechanical and structural properties and are emerging as potentially important for a number of industrial applications including organic photovoltaic cells. One of the benefits of using soluble CNTs is that they are amenable to solution-based, low-cost, commercial manufacturing methods. The Zetasizer Nano is proving to be an easy-to-use tool for tracking and optimizing the functionalization reactions...

 

  Exceptional Sensitivity of the new OMNISEC GPC/SEC System Excites Attendees at SCM-7

The ground-breaking sensitivity of Malvern Instruments’ new OMNISEC gel permeation chromatography/size exclusion chromatography system generated significant excitement from scientists meeting at the Seventh International Symposium on the Separation and Characterization of Natural and Synthetic Macromolecules (SCM-7), when the system made a well-received debut late in January.

malvern“Delegates were particularly enthusiastic about OMNISEC’s sensitivity,” said Paul Clarke, Industrial Portfolio Manager at Malvern Instruments. “Announcing ‘the most sensitive light scattering detector on the market’ is one thing but seeing what that actually means in practice is another. Demonstrations of the system measuring the molecular weight (MW) of a 100,000 Da Polystyrene standard with just a 100 ng of sample made a big impression and...

 

  Malvern Expands Recently Acquired MicroCal Range with Launch of two New-Generation Calorimeters

All new data analysis software in Malvern MicroCal PEAQ-ITC systems delivers greatest accessibility to life science users at every level 

MicroCal PEAQMalvern Instruments has launched two new-generation isothermal titration calorimeters (ITC), advancing its recently acquired MicroCal range to further support life science researchers studying biomolecular interactions. The new manual Malvern MicroCal PEAQ-ITC and fully automated Malvern MicroCal PEAQ-ITC Automated systems are designed to deliver the enhanced functionality and robust performance now demanded of...

 

  Analytical Strategies that Support OSD Formulation: A new Whitepaper from Malvern Instruments

A new whitepaper from Malvern Instruments provides detailed guidance on the analytical technologies that help to accelerate oral solid dosage (OSD) product formulation to a successful conclusion.

Raman Spectroscopy‘Analytical techniques with a place in the oral solid dosage formulation toolkit’ reviews the regulatory and QbD framework associated with OSD formulation and demonstrates how Malvern systems can be used to generate the data required. The goal of formulation is to incorporate an identified drug substance into a successful pharmaceutical product. The regulatory framework for OSD products highlights the need to comprehensively...

 

  Malvern to Show New Analytical Systems at Pittcon 2015 and Present Five Educational Short Courses

As part of its rapidly expanding range of analytical tools for materials characterization, Malvern Instruments will showcase a new chromatography system and detectors at Pittcon 2015 (Mar 8th – 12th, New Orleans, USA). New additions to Malvern’s recently acquired MicroCal microcalorimetry range will also be on display.

MAL JOB 3086AThe new systems will be shown alongside the Mastersizer 3000 laser diffraction particle size analyzer, complete with its recently introduced HydroSight imaging and Hydro SV small volume liquid dispersion accessories. Visitors can also explore nanoparticle characterization with the Zetasizer Nano and NanoSight Nanoparticle Tracking Analysis (NTA) systems, and morphological and chemical characterization with the Morphologi G3-ID, also...

 

  Malvern’s New OMNISEC GPC/SEC Platform Brings Ground-Breaking Performance to the Analysis of Polymers, Proteins and Other Macromolecules

A completely new gel permeation/size exclusion chromatography (GPC/SEC) platform from Malvern Instruments breaks new ground in delivering the high performance, ease of use and productivity demanded in today’s analytical laboratories.

OMNISEC RESOLVEMalvern’s innovative OMNISEC platform integrates highly efficient sample separation via the OMNISEC RESOLVE module and high sensitivity analysis using OMNISEC REVEAL, a fully integrated multi-detector array. The system has applications wherever there is a need for detailed analysis and understanding of natural or synthetic polymers, proteins and macromolecules. GPC/SEC is a two-step analytical process that involves separating a...

 

  Accelerating Deformulation: A New Whitepaper from Malvern Instruments for Generic Tablet Development

A new whitepaper from Malvern Instruments on Oral Solid Dose (OSD) deformulation demonstrates how the analytical technique of Morphologically Directed Raman Spectroscopy (MDRS) can be used to accelerate the development of generic products to a successful conclusion.

Oral Solid DoseDeformulation, the unpicking and investigation of a reference labeled drug (RLD), enables generic developers to understand the features of a product that define its clinical performance. “Accelerating the deformulation workflow for oral solid dosage forms” reviews the current regulatory landscape associated with generic development and considers the workflow for preparing OSD product Abbreviated New Drug Applications (ANDAs)...

 

  Viscotek GPC/SEC from Malvern Instruments Delivers Performance-Defining Information for University Team Developing Polymer Coated Nanoparticles

Researchers at the University of Lethbridge, Alberta, Canada, are using Viscotek multi-detector Gel Permeation/Size Exclusion Chromatography (GPC/SEC) (Malvern Instruments, UK) to analyze performance defining polymer features in the development of novel polymer coatings for metal nanoparticles.

malvern scientist“Multi-detection GPC/SEC helps us to monitor and control reaction conditions to engineer advanced polymer coatings which stabilize nanoparticle suspensions to ease their handling and preserve their industrial value,” said Dr. Farhad Faghihi, Research Associate at the University of Lethbridge. “GPC/SEC is the only technique that we have to determine molecular weight and molecular weight distribution with the speed and accuracy...

 

  Malvern Process Specialist Presents On-Line Nano-Particle Characterization at IFPAC 2015

Alon Vaisman, Product Development Manager for Process Systems at Malvern Instruments, will speak about two quite different analytical techniques and their applications as part of the ‘Particle Characterization’ session at this year’s IFPAC¼ (International Forum on Process Analytical Technology and Quality by Design) Annual Meeting.

Alon VaismanIn separate presentations he will discuss the ‘Applications of Dynamic Light Scattering as PAT for on-line nano-particle characterization’ and ‘In-situ monitoring of high shear and fluid bed processing using spatial filter velocimetry’. Both address areas of growing emphasis in pharmaceutical production. The continuing importance of large molecule based therapeutics, and the drive to reduce the particulate size of small molecule APIs, is bringing new challenges for...

 

  Malvern Zetasizer APS Delivers Unattended Protein Screening for Medicon Valley’s SARomics Biostructures

An automated dynamic light scattering system from Malvern Instruments has become established as an essential part of the analytical toolkit used by SARomics Biostructures AB, a leading provider of protein 3D structure determination and structure-based drug design services.

custom/MAL JOB 3048The Zetasizer APS automated plate sampling system is supporting the systematic study of the aggregation behavior of proteins, a fundamental component of the services provided by SARomics Biostructures. The company, which is based in Lund, Sweden within the biotech cluster of the Medicon Valley, is a research-intensive organization with clients around the world. The Zetasizer APS is a robust, simple-to-operate system that uses laser light scattering to determine a number of parameters associated...

 

  Morphologi G3-ID Accelerates Environmental Particle Research at Southern Cross University, Australia

A Morphologi G3-ID particle characterization system from Malvern Instruments is opening cutting-edge research opportunities in environmental science at the School of Science, Environment and Engineering, Southern Cross University (SCU), in Australia.

MAL JOB 3046The Morphologi G3-ID, which is sold and supported in Australia by ATA Scientific, combines automated particle imaging with Raman spectroscopy to deliver particle size, morphology and chemical identification of particles within a dispersion. The technique is helping users to better understand the composition and behavior of natural particles within the environment and is generating substantial cost and efficiency savings in areas that...

 

  Malvern Releases New Guidance on the use of Automated Imaging for Agglomerate Detection

Malvern Instruments has released new guidance on using automated image analysis to detect and quantify agglomerates.

MAL JOB The ability of uncontrolled agglomeration to substantially impact the performance and value of powder products makes efficient agglomerate detection vital across a number of industries. ‘Identification of agglomerates using automated image analysis’ presents practical strategies for efficiently and robustly differentiating agglomerates from primary particles, to support product development, QC and process troubleshooting....

 

  New Whitepaper Explores how Malvern Instruments Extends a QbD Approach to Instrument Design

‘Extending the boundaries of QbD’, a new whitepaper from Malvern Instruments, explores the application of Quality by Design (QbD) principles to the development of analytical instrumentation and the benefits this brings for users.

MAL JOBTaking the example of Malvern’s development of the Mastersizer 3000 particle size analyzer, the authors illustrate how instrument companies are aligning with the QbD philosophy. This offers pharmaceutical customers the reassurance of closely similar working practices and products that meet exacting customer standards. The central idea of QbD is that quality should be built into a product from the outset. It is an approach based on...

 

  Malvern Zetasizer APS delivers unattended protein screening for SARomics Biostructures

An automated dynamic light scattering system from Malvern Instruments has become established as an essential part of the analytical toolkit used by SARomics Biostructures AB, a leading provider of protein 3D structure determination and structure-based drug design services.

The Zetasizer APS automated plate sampling system is supporting the systematic study of the aggregation behavior of proteins, a fundamental component of the services provided by SARomics Biostructures. The company, which is based in Lund, Sweden within the biotech cluster of the Medicon Valley, is a research-intensive organization with clients around the world.

 

  New Mastersizer 3000 Hydro SV Reduces Sample Volume for Particle Size Analysis to just a few Milliliters

The new Mastersizer 3000 Hydro SV small volume liquid dispersion unit delivers reliable particle size measurement using just a few milligrams of sample.

MALJOB3002Particle size is a performance-defining parameter for many industrial products. The ability to measure small samples sizes becomes crucial when sample availability prevents the use of larger amounts of material. This is especially true during early stage product development, for example. By minimizing sample and dispersant use the Hydro SV also reduces the development, purchase and disposal costs associated with routine analysis. Efficient sample dispersion...

 

  Malvern Instruments Zetasizer Nano Plays Key Role in Research to Develop 3D Cell Cultures

Researchers at the School of Engineering and Materials Science, Queen Mary University London (QMUL), are using a Malvern Instruments Zetasizer Nano to provide particle size and charge data that is being used in the development of innovative hydrogel matrices for 3D cell culture.

MAL JOB 2964bThe Zetasizer Nano’s high performance electrophoretic light scattering capabilities are allowing researchers to better understand the nature of the electrostatic interactions between proteins and peptides. These measurements are crucial to developing bespoke cell culture platforms for the production of specific biologically significant hydrogel. By creating hydrogel structures based on the charge of target biomolecules, researchers at QMUL aim to...

 

  Malvern Instruments satisfies appetites for high-end food R&D with exhibition at FoodTech 2014

Malvern Instruments will demonstrate how the Kinexus rotational rheometer and Mastersizer 3000 laser diffraction particle sizing system enable smarter, faster and more effective strategies for food development at FoodTech Processing & Packaging.

The conference takes place at MCH Messecenter Herning, Denmark, from 28 to 30 October 2014. Malvern’s food characterization experts will be on hand throughout the event to demonstrate the analytical strategies that help R&D and QC scientists develop high performance products with enhanced consumer appeal. Visit Malvern on stand M9912....

 

  Malvern Explores Rheology for Protein Formulation at 2nd Protein-Protein Interaction Conference

Malvern Instruments will contribute a scientific poster at the 2014 Protein-Protein Interaction Conference, October 23-24, Boston, MA, USA.

MAL JOB 3012The poster describes new work on rheological approaches to protein stability studies during biologics formulation and will be presented by Matt McGann, Malvern Instruments Life Science Sales and Application Specialist for the Americas. The study of rheology in protein formulation and biotherapeutic development is considered to be a developing and ultimately essential measurement. The Malvern presentation ‘Characterizing the stability of...

 

  Malvern Instruments marks 3rd anniversary of the Mastersizer 3000 with the launch of imaging accessory

As Mastersizer 3000, the world-leading laser diffraction particle size analyzer, celebrates its 3rd birthday, Malvern Instruments is delivering even smarter particle sizing with the launch of two new additions to the Mastersizer portfolio.

Join Malvern’s live web event on 9 October

 

  Malvern explores rheology for protein formulation at 2nd Protein-Protein Interaction Conference

Malvern Instruments will contribute a scientific poster at the 2014 Protein-Protein Interaction Conference, October 23-24, Boston, MA, USA.

Malvern InstrumentsThe poster describes new work on rheological approaches to protein stability studies during biologics formulation and will be presented by Matt McGann, Malvern Instruments Life Science Sales and Application Specialist for the Americas. The study of rheology in protein formulation and biotherapeutic development is considered to be a developing and ultimately essential measurement....

 

  Malvern Technology Delivers Malvern Reliability in Multi-Disciplinary Lab at Queen Mary University London

The cross-disciplinary capabilities of Malvern Instruments’ technology are being fully exploited at Queen Mary University London.

 Zetasizer NanoThe Zetasizer Nano, NanoSight Nanoparticle Tracking Analysis (NTA) and Mastersizer 2000 systems are all employed within the university’s multi-disciplinary lab. The instruments serve a wide variety of research groups working in areas as diverse as silica coating formulation through to tissue regeneration, demonstrating the value that Malvern’s robust technology brings throughout the scientific arena. “Our lab is part of The School of Engineering and...

 

  Malvern’s Dr Alan Rawle Talks TLAs in Plenary Lecture at Particulate Systems Analysis Conference

Dr Alan Rawle, Applications Manager for Malvern Instruments, will give a plenary lecture at Particulate Systems Analysis (PSA) 2014, organized by the Royal Society of Chemistry’s Particle Characterization Group.

alan rawleThe event takes place from 15-17 September 2014 at the Manchester Conference Centre, Manchester UK, and this year incorporates the UK Particle Technology Forum and Fine Bubble Symposium. The title of Dr Rawle’s lecture is ‘TLAs and the 4Qs in relation to elucidation of particle sizing issues’ where, of course, TLA stands for ‘Three-Letter Acronyms’. “The prime objective is entertainment with an educational experience as a sideline,” said Alan Rawle. “I’ve used TLAs over the years as an...

 

  Analytical Solutions from Malvern Instruments Support University of Wisconsin-Milwaukee Researchers in Understanding Environmental Effects of Nanomaterials

Researchers at The School of Freshwater Science, University of Wisconsin-Milwaukee, USA, are using NanoSight Nanoparticle Tracking Analysis (NTA) from Malvern Instruments to investigate the effects of nanoparticle contaminants on freshwater organisms.

malThe work, which is at the forefront of nanotoxicity testing, has focused on using the unique size, concentration and visualization capabilities provided by NTA to monitor how specific changes in nanoparticle surface chemistry influence the impact of the particles on molecular species in environmental media. NTA is used as part of an ensemble of analytical techniques that includes Dynamic Light Scattering (DLS) with the...

 

  Malvern Instruments completes acquisition of MicroCal and announces purchase of Archimedes product from Affinity Biosensors

Malvern Instruments Ltd has announced that it has completed the acquisition of MicroCal from GE Healthcare Life Sciences and has also purchased the Archimedes particle characterization system from Affinity Biosensors LLC 

The agreement to purchase GE Healthcare Life Sciences’ MicroCal business was announced on 4 June 2014 by Malvern’s parent company Spectris plc, and completion follows regulatory approval of the transaction. MicroCal microcalorimeters are now part of the Malvern Instruments portfolio and are being sold and supported by Malvern Instruments with immediate effect. Users of MicroCal systems have been notified directly of any changes and full details of the product range are available on the Malvern website....

 

  Malvern Instruments’ New Zetasizer Helix Combines Dynamic Light Scattering and Raman Spectroscopy for Advanced Protein Structure Analysis

The new Zetasizer Helix from Malvern Instruments is a powerful tool for early stage biopharmaceutical development that enables the detailed study of mechanisms of protein aggregation.

Zetasizer HelixThis new system combines industry-leading Zetasizer dynamic light scattering (DLS) technology, for sizing of proteins and other biomolecules, with Raman spectroscopy. Raman spectroscopy enables monitoring of the changes in secondary and tertiary protein structure. The combination of DLS and Raman spectroscopy allows measurement of protein size and structure from a single small volume sample, providing unique insight into...

 

  New Brochure from Malvern Instruments Guides GPC/SEC Detectors Choice

A new brochure from Malvern Instruments details the range of detectors available for Gel Permeation/Size Exclusion Chromatography (GPC/SEC).

malvern brouchureIt also provides scientists with the background required to choose the detector array most appropriate to maximizing information flow and experimental productivity. Available as standalone units, or as part of a fully integrated Viscotek multi-detection GPC/SEC system, Malvern’s GPC/SEC detectors provide highly accurate analysis of polymer and protein macromolecular features, such as molecular weight, and combine to offer advanced insight into molecular structure...

 

  Regional Growth Fund success sees Malvern Instruments stepping up UK recruitment

Malvern Instruments has been successful in securing £3 million support from the UK Government’s Regional Growth Fund (RGF) that will lead to the creation of 47 new jobs in the UK over the next five years.

This funding will support the research and development of new analytical instrumentation to serve the fast-growing nanomaterials and bioscience sectors, helping maximize Malvern’s export opportunities in these global markets. The company, which currently employs around 340 people in the UK and approaching 480 more in locations around the world, has already started recruiting to fill a variety of new posts....

 

  Malvern Instruments publishes new whitepaper that explores Analytical Quality by Design

A new whitepaper on the application of Analytical Quality by Design (AQbD) to particle size assessment has been published by Malvern Instruments.

AQbD is an innovative approach to the development and validation of analytical methods that brings the benefits of Quality by Design (QbD) to pharmaceutical analysis. Malvern’s new whitepaper, ‘Beyond SOPs – Exploring the rigor and requirements of Analytical QbD’, introduces the AQbD concept, explains the associated workflow and illustrates how to apply AQbD when developing methods for laser diffraction particle sizing. The whitepaper is freely available for download from the Malvern resource center....

 

  DĂ©partement Environnement et Agro-biotechnologies use Nanoparticle Tracking Analysis

Researchers from the Département Environnement et Agro-biotechnologies at the CRP - Gabriel Lippmann in Luxembourg use Nanoparticle Tracking Analysis for toxicology studies 

Malvern photoThe DĂ©partement Environnement et Agro-biotechnologies (EVA), of the Centre de Recherche Public - Gabriel Lippmann, Luxembourg, employs NanoSight Nanoparticle Tracking Analysis (NTA) method from Malvern Instruments to perform environmental analysis and toxicological testing of nanoparticles...

 

  Malvern Instruments launches the new Zetasizer NanoSampler for high throughput sample delivery

The new Zetasizer NanoSampler from Malvern Instruments is a versatile, compact, fully automated sample delivery system for the Zetasizer Nano, the most widely used system for nanoparticle and colloid characterization.

nanosmaplerDelivering precise and reproducible automated sample loading, and accommodating up to 96 sample vials, the NanoSampler enables unattended operation of the Zetasizer Nano, to maximize analytical productivity. It is especially suitable for laboratories where reproducibility is critical and where multivariate studies are routine. The new NanoSampler will work with all of the sizing systems in the Zetasizer Nano instrument range. This range includes both exceptionally high performance and entry level systems that measure particle and molecular size using dynamic light scattering, covering a size range from less than one nanometer up to several microns....

 

  Researchers from the DĂ©partement Environnement et Agro-biotechnologies at the CRP - Gabriel Lippmann in Luxembourg use Nanoparticle Tracking Analysis for toxicology studies

The DĂ©partement Environnement et Agro-biotechnologies (EVA), of the Centre de Recherche Public - Gabriel Lippmann, Luxembourg, employs NanoSight Nanoparticle Tracking Analysis (NTA) method from Malvern Instruments to perform environmental analysis and toxicological testing of nanoparticles.

Researchers within the EVA department are using the technique of Nanoparticle Tracking Analysis (NTA) for the characterization of nanoparticles within their toxicological studies. A team led by toxicologist Dr. Arno Gutleb is working closely with colleagues in the Département Science et Analyse des Matériaux (SAM) both to characterize the particles that they produce and to investigate the environmental and toxicological impact of these and other nanomaterials.....

 

  Malvern Instruments’ Alan Rawle is invited speaker in Brian Scarlett Memorial Session at World Congress for Particle Technology in Beijing

Dr. Alan Rawle, Applications Manager for Malvern Instruments, has been invited to speak as part of the Brian Scarlett Memorial Session at the 7th World Congress for Particle Technology.

Alan Rawle

Dr Rawle’s presentation will discuss ‘Sampling – another Cinderella of particle size analysis’ and he will highlight the importance of representative sampling for particle size analysis, explaining how  to employ statistical methods to obtain accurate and reproducible results. “Brian Scarlett was one of the most recognized, respected and effective leaders in particle technology and it is a real honor to be contributing to this memorial session,” said Alan Rawle....

 

  Malvern reports on the publication of the 1000th peer-reviewed paper to cite NanoSight’s Nanoparticle Tracking Analysis, NTA

Alexander Seifalian is Professor of Nanotechnology and Regenerative Medicine at UCL Centre for Nanotechnology and Regenerative Medicine within the Division of Surgery and Interventional Science at University College London, UK. His research focus is on the development of human organs using nano composite materials and stem cells as well as treatment of cancer using nanoparticles.

Professor Alexander Seifalian and Dr Achala de MelWith nanoparticles requiring rapid and repeatable measurement, Professor Seifalian selected Malvern’s NanoSight Nanoparticle Tracking Analysis (NTA) system. Previous to this, he had used techniques including scanning electron microscopy (SEM) and atomic force microscopy (AFM) but found that NTA made measuring size easier and more accurate. Professor Seifalian’s paper, "Fumed Silica Nanoparticle Mediated Biomimicry for Optimal Cell-Material Interactions for Artificial Organ Development” published in the Journal of Macromolecular Biosciences...

 

  Malvern Instruments is Premier Sponsor of Inaugural PEGS China Where the Company will Present its Analytical Toolkit for Biopharma Applications

Malvern Instruments is proud to be a premier sponsor of the inaugural PEGS China meeting.

Malvern bioscience

The PEGS China Protein & Antibody Engineering and Development summit is presented by Cambridge Healthtech Institute and takes place in Shanghai from 1 - 3 April 2014. Malvern is participating in both the conference and the associated exhibition, with Dr Wei Qi, Senior Scientist within Malvern’s Bioscience Development Initiative, presenting a paper on ‘Emerging techniques for therapeutic protein characterization – viscosity, stability and sub-visible particles’....

 

  Malvern Instruments webinar introduces new m-VROCi for industrial viscosity measurements

Following the launch of the new m-VROCi, Viscometer/Rheometer On a Chip, at Pittcon 2014, Malvern Instruments will focus on the unique technology of this system and the considerable benefits it delivers in a webinar on 16 April 2014. The m-VROCi provides safe, accurate viscosity measurement for low viscosity industrial fluids, under conditions that reflect those that apply during end-product use.

m-VROCiMalvern’s webinar will show how the innovative microfluidic technology at the heart of the m-VROCi works. The presenters will explore how the instrument meets an established need within industry for accurate and robust measurement of low viscosity formulations, most especially at ultra-high shear rates. Other benefits of the m-VROCi system include completely enclosed measurement for safe and reliable analysis of highly volatile or environmentally-sensitive samples, and the generation of accurate viscosity data using sample volumes as low as 50 ”L, essential for scarce or high value materials...

 

  New partnership between Malvern Instruments and RheoSense brings m-VROCi to industrial markets

New partnership between Malvern Instruments and RheoSense brings m-VROCi to industrial markets

New partnership between Malvern Instruments and RheoSense brings m-VROCi to industrial markets“We are delighted to be working with RheoSense, Inc to bring the benefits of the m-VROCi to industrial customers across the globe,” said Steve Carrington, Product Manager for Malvern Instruments. “The m-VROCi is highly complementary to the existing Malvern rheological portfolio, extending robust, fully enclosed (no solvent loss) flow curve measurement into areas that simply aren’t accessible with alternative rheological instrumentation...

 

  Malvern Instruments shows NanoSight Nanoparticle Tracking Analysis at BioNanoMed 2014

Malvern Instruments will demonstrate NanoSight Nanoparticle Tracking Analysis (NTA) at BioNanoMed 2014

Malvern Instruments shows NanoSight Nanoparticle Tracking Analysis at BioNanoMed 2014The 5th International Congress on Nanotechnology, Medicine and Biology, which takes place in Krems, Austria from 26 – 28 March. A specialist from the company will also make a 10-minute presentation as part of the business sessions held alongside the conference. The acquisition of NanoSight in September 2013 has extended Malvern’s range of analytical solutions for characterization at the nanoscale, with NTA ideally complementing the company’s Zetasizer Nano, Archimedes and Viscotek SEC systems...

 

  Malvern scientists present emerging protein characterization techniques at Biotherapeutics Analytical Summit

Dr Wei Qi and Dr Linda Kidder, both senior scientists within Malvern Instruments’ Bioscience Development Initiative, will present work on techniques for protein analysis at the 2014 Biotherapeutics Analytical Summit which takes place in Baltimore MD, USA, from 24-27 March.

analytical toolbox for biopharmaceutical developmentThe topic of Dr Wei Qi’s poster is ‘Emerging Techniques for Therapeutic Protein Characterization - Viscosity, Stability and Sub-Visible Particles’  while Dr Linda Kidder’s oral presentation on 25 March will discuss ‘Improved Understanding of Association Between Protein Colloidal and Conformation Stability with Combined DLS/Raman’. Dr Kidder will describe how the combination of dynamic light scattering (DLS) and Raman spectroscopy presents a novel approach to protein therapeutics characterization.....

 

  Malvern Instruments at Analytica 2014

Malvern Instruments shows how complementary technologies solve analytical challenges from biopharm to bulk materials 

Malvern Viscosizer 200Malvern Instruments growing range of analytical instrumentation now includes extended solutions for characterization at the nanoscale and an expanded portfolio for those working in preformulation and formulation development in the biopharmaceuticals sector. At Analytica 2014 (1-4 April, Munich, Germany) Malvern will demonstrate how using complementary technologies to address analytical challenges, across many different industry sectors and applications, delivers the detailed information and understanding required to engineer efficient processes and high quality products...

 

  Malvern specialist to explore use of Nanoparticle Tracking Analysis for characterizing extracellular vesicles at ISEV 2014

Pauline Carnell, Senior Application Scientist at Malvern Instruments, will present a paper at ISEV 2014 discussing ‘The practical use of nanoparticle tracking analysis (NTA) to characterise extracellular vesicles in general and when using fluorescence markers’.

ISEV 2014 is a meeting of the International Society for Extracellular Vesicles. It takes place in Rotterdam, The Netherlands, from 30 April to 3 May 2014, with an education day on 29 April. Pauline Carnell will present the paper, co-authored with colleagues Andrew Malloy, Agnieszka Siupa, Patrick Hole and Bob Carr, on 30 April. All the authors are experts in the technology and application of NanoSight Nanoparticle Tracking Analysis (NTA). NanoSight NTA systems are now offered as part of Malvern’s portfolio of analytical solutions for characterization at the nanoscale...

 

  Malvern Instruments announces guest presenter for March 18th protein characterization webinar

Renowned protein scientist Prof. Dr. John F. Carpenter shows how combining Dynamic Light Scattering with Raman Spectroscopy delivers new insights in protein stability, aggregation and structure

John Carpenter, PhDMalvern Instruments welcomes Prof. Dr. John F. Carpenter, from the University of Colorado Center for Pharmaceutical Biotechnology, as a guest presenter contributing to the company’s current series of webinars. Professor Carpenter is a renowned expert in mechanisms for protein degradation and stabilization in pharmaceutical formulations. In his webinar on 18 March 2014 he will discuss how the combination of dynamic light scattering technology with Raman spectroscopy delivers new insights into the measurement and prediction of protein stability, aggregation and high order structure....

 

  New partnership between Malvern Instruments and RheoSense brings m-VROCi to industrial markets

Malvern Instruments Ltd (Malvern, UK) has announced an exclusive global distribution agreement with RheoSense, Inc. (San Ramon, CA, USA) to promote, market, sell and support the VROC product range into industrial applications.

Malvern InstrumentsThe agreement enables Malvern to add the m-VROCi, microfluidic Viscometer/Rheometer On a Chip, to its existing portfolio of rotational and capillary rheometers, extending the company’s offering to industrial customers across the globe. Delivering accurate, robust, fully enclosed viscosity measurement, at high shear rates, the m-VROCi addresses an established need to measure low viscosity fluids under process relevant conditions. The results have proven application for the characterization and enhancement of inkjet inks, coatings, rechargeable batteries, lubricants, chemical and food additives, and drink formulations...

 

  Publication shows use of Morphologi G3-ID for component-specific particle characterization of pharmaceutical cream

The application of morphologically directed Raman spectroscopy to characterizing the component-specific particulate properties of the active components in a topical pharmaceutical cream is described in an application note from Malvern Instruments.

 Morphologi G3-IDWhile it is relatively straightforward to determine the particle size distributions of the individual components of a drug formulation before they are formulated as a blend, doing so post-blending is more challenging. Now, the Morphologi G3-ID, which combines automated image analysis with Raman spectroscopy in a single instrument, enables component-specific particle size and shape distributions to be obtained from a blend. The results of this analysis can provide....

 

  Malvern Instruments’ 2014 webinar program gets underway with light scattering for biopharma

Malvern Instruments has kicked off another year of its highly popular open-access webinar program and on 21 January the ‘Step into the Light’ webinar offers insight into the use of dynamic light scattering technology to improve the quality of biopharmaceutical data in purity profiles.

Malvern InstrumentsThis is followed on 23 January by ‘Optimization and characterization of nanomaterials for drug delivery applications. Part 1 – Liposomes’.  ‘Where do I find source material in light scattering?’ is the topic on 28 January, and the first of this year’s laser diffraction masterclass series goes out live on 30 January. Accurately identifying impurities and generating purity profiles presents substantial challenges to biopharmaceutical developers, who require the most sensitive analysis methods available. ‘Step into the Light’ will explore the analytical challenges within biopharmaceutical development

 

  Malvern shows newly acquired Nanoparticle Tracking Analysis systems at Pittcon 2014

Malvern Instruments brings a new addition to Pittcon in 2014, exhibiting NanoSight Nanoparticle Tracking Analysis (NTA) systems within its growing portfolio of analytical solutions for industry and academia.

Malvern Instruments Pittcon 2014 is Malvern’s first major exposition in the US since acquiring NanoSight in September 2013, a move which resulted in the addition of NTA to Malvern’s technologies for particle sizing and counting at the nanoscale. NTA systems will be on show alongside the Zetasizer Nano and the new Viscotek SEC-MALS 20 GPC/SEC detector.  Also on the Malvern booth is the Mastersizer 3000 laser diffraction particle size analyzer featuring new software....

 

  New Malvern data demonstrate monoclonal antibody characterization using the Viscotek SEC-MALS 20

Malvern Instruments has posted a new application note demonstrating the use of the company’s Viscotek SEC-MALS 20 multi angle light scattering (MALS) detector for size exclusion chromatography (SEC) in the analysis of monoclonal antibodies.

New Malvern data demonstrate monoclonal antibody characterization using the Viscotek SEC-MALS 20

The application note, ‘Molecular weight measurements of an antibody using Viscotek SEC-MALS 20’, reports experimental data for the analysis of aggregates within monoclonal antibody formulations and can be freely downloaded. Monoclonal antibodies are being targeted for use in a growing range of therapeutic applications. Measuring the molecular weight of the protein, monomer, oligomers and aggregates within the sample and in formulations is an important part of assessing their safety and efficacy as drugs.....

 

  New Malvern Instruments application note examines laser diffraction particle sizing in drilling muds

A new application note from Malvern Instruments explores the role of particle size and the importance of particle size measurement in optimizing the formulation of drilling muds used in oil extraction processes.

Mastersizer 3000The particle size of drilling mud components exerts a significant influence on the performance of the final drilling mud product. Rapid, reliable measurement and control of particle size is especially important when tailoring drilling mud formulations for individual geological situations and drilling operations. This new publication focuses on the use of laser diffraction particle sizing for this application, exploring the steps involved and providing examples of typical data generated.....

 

  The proof is in the particle sizing


New customer feedback points up benefits of the Mastersizer 3000

The second anniversary of the Mastersizer 3000

A recent webinar showcasing new software features for the Mastersizer 3000 proved an opportunity for Malvern Instruments’ customers to reflect on how, two years on from its launch, this groundbreaking instrument is delivering valuable benefits. Customers cite its small footprint, truly intuitive and intelligent software interface, as well as the ease of transferring from an existing system to the new instrument, as the most popular features. The new software further enhances these elements of performance and was demonstrated during the webinar...

 

  Malvern Viscotek SEC-MALS 20 detector launch triggers record light scattering white paper downloads

The launch of Malvern Instruments’ Viscotek SEC-MALS 20 chromatography detector has triggered record downloads of one of the supporting white papers ‘Static light scattering technologies for GPC/SEC explained’, underlining the enthusiasm amongst users for straightforward information on GPC/SEC analysis.

The new Viscotek SEC-MALS 20 has more detectors than any other commercially available MALS system for GPC SEC

The recent addition of Viscotek SEC-MALS 20 to Malvern’s range of detectors puts the company in the unique position of being the sole provider of every commercially available light scattering technology for GPC/SEC. Customers can therefore be assured of a truly unbiased choice of detector solutions. The popular white paper is just one of a suite of educational information and application notes provided by Malvern’s specialist team to help users select the right detector for their application...

 

  New data on laser diffraction particle sizing for powder metallurgy now available online

Malvern Instruments has recently released an article detailing the use of laser diffraction particle size analysis  for powder metallurgy applications.

Measuring Metal Powders

Entitled ‘Using laser diffraction to measure particle size distributions’, the article presents new data on how laboratory and on-line laser diffraction provide the comprehensive particle size and size distribution data required to support metal powder product and manufacturing process development. Powder metallurgy - the production of a solid object from the sintering of a fine metal powder - is a versatile and precise method for creating a wide range of metal components.....

 

  Malvern Instruments extends direct support with opening of new office in Mexico City

In a move that reflects continued sales growth in Mexico, Malvern Instruments has opened a new office in Mexico City.

New Malvern Premise in MexicoOperational since August 2013, the Mexico office provides both pre- and after- sales support to a growing customer base. It is also the venue for an increasing number of advanced training courses and seminars, and is part of Malvern’s operational expansion in Mexico and throughout Latin America as a whole. The opening of the office in Mexico comes just a year after the establishment of a sales and applications laboratory in Sao Paolo, Brazil...

 

  Software a significant factor: NSL Analytical Services chooses Mastersizer 3000 for particle sizing

A refreshingly modern and inviting operating environment led independent, commercial materials testing laboratory NSL Analytical Services (Cleveland, US), straight to the Mastersizer 3000 from Malvern Instruments when it came to choosing a laser diffraction particle size analyzer to extend testing capabilities.

NSL Analytical Services use the Mastersizer 3000 from Malvern Instruments to extend testing capabilities

“The software really is the shining star of this product,” said Brian Bacher, Technical Specialist at NSL. “It makes the Mastersizer 3000 feel radically different from other systems on the market and a really great instrument to use. I especially like the live trends which make it so quick and easy to compare data sets,” he continued. NSL provides physical material testing to multiple verticals including the aerospace, ceramics and powder metallurgy industries...

 

  Malvern Instruments celebrates Mastersizer 3000’s second anniversary with new software developments

Malvern Instruments is marking the second anniversary of the market leading Mastersizer 3000 laser diffraction particle sizing system with the introduction of a host of innovative software updates and an extension to the Mastersizer family, the Mastersizer 3000E.

Celebrating 2 years on the market – the Mastersizer 3000 from Malvern Instruments

A global leader for particle sizing, Malvern’s Mastersizer range has become synonymous with laser diffraction. The Mastersizer 3000 delivers unique performance and productivity benefits, wrapped in a stylish, compact and practical instrument design. New software features, developed in response to customer feedback, now make it easier than ever to obtain accurate particle size information....

 

  Malvern Instruments launches new models of the Kinexus rotational rheometer

Malvern Instruments has introduced two new models to its Kinexus line of rotational rheometers.

Kinexus range of rotational rheometersThe new Kinexus pro+ and Kinexus ultra+ incorporate enhancements to Malvern’s unique proprietary air bearing technology, the performance defining technology that sits at the heart of the rotational rheometer. These enhancements add to the capabilities of Malvern’s rotational rheometers for R&D by extending the range and robustness of test conditions that can be applied during rheological characterization. Full details of the new Kinexus models are on the Malvern website where visitors can also download a brochure describing the complete Kinexus range...

 

  Coriolis Pharma is first CRO in the world to routinely use Archimedes from Malvern Instruments

Team also publishes paper examining ability to distinguish between protein aggregates and oil droplets in biopharmaceutical formulations

ArchimedesCoriolis Pharma (Martinsried, Germany) has become the first pharmaceutical contract research organization in the world to routinely use Archimedes, a new analytical instrument supplied by Malvern Instruments. Coriolis Pharma specializes in formulation development for biopharmaceuticals such as proteins, peptides and vaccines and offers a wide variety of services to support product development...

 

  Malvern Instruments demonstrates analytical solutions for entire pharmaceutical lifecycle at 2013 AAPS Annual Meeting & Exposition

Malvern Instruments is to showcase the company’s range of analytical solutions for pharmaceutical materials characterization at the 2013 AAPS Annual Meeting & Exposition, from 11-14 November in San Antonio TX, USA.

Viscotek SEC-MALS 20 Visitors can tap into the expertise of Malvern’s technical and applications specialists and find out how the company’s range of technologies and instrumentation provides valuable information across the entire pharmaceutical development spectrum, from pre-formulation through to quality control. New systems on show will include the Viscotek SEC-MALS 20 multi-angle light scattering detector for GPC/SEC. The new Viscotek SEC-MALS 20 has more detectors than any other commercially available multi angle light scattering system

 

  Malvern Instruments acquires nanoparticle characterization company NanoSight

Malvern Instruments Ltd (Malvern, UK), a leading global provider of instrumentation and expertise for materials and biophysical characterization, has acquired nanoparticle characterization company NanoSight Ltd (Amesbury, UK). The acquisition was completed on Friday 27 September 2013.

shaking handsNanoSight has developed and commercialized a unique and patented technology, Nanoparticle Tracking Analysis (NTA). The company’s instrumentation and software enable the rapid and simultaneous multi-parameter analysis and characterization of many different types of nanoscale particles. With their ability to analyze particle size, concentration, zeta potential and aggregation, NanoSight systems are closely aligned with Malvern’s market-leading Zetasizer range, extending Malvern’s solutions for those working at the nanoscale....

 

  Malvern Instruments adds fiber analysis capabilities in new software for Morphologi G3 system

Malvern Instruments has introduced new software for the Morphologi G3 particle characterization system, extending the instrument’s capabilities to include the detailed measurement of fibers.

Malvern Instruments adds fiber analysis capabilities in new software for Morphologi G3 system

The Morphologi G3 measures the size and shape of particles by image analysis and the new software function delivers accurate measurement of fiber-specific parameters, including fiber total length, fiber width, fiber straightness and fiber elongation. Many manufactured materials and intermediates are fibrous in nature, including insulation products, reinforcing materials, textiles and of course carbon fiber. Each has its own unique properties and a detailed understanding of the individual properties is essential from R&D through to manufacturing and quality control...

 

  Publications show Zetasizer APS flexibility for automated DLS measurement of multiple protein sample

A set of application notes from Malvern Instruments demonstrates the sample integrity, flexibility and lack of cross contamination during automated, rapid screening of protein samples using the Zetasizer Auto Plate Sampler (APS) dynamic light scattering (DLS) system.

Zetasizer APS

Enabling automated measurements of multiple samples, the Zetasizer APS delivers the same high sensitivity, high specification DLS measurements as other systems in Malvern’s well-known Zetasizer series, making it ideal for protein applications. Easy data interpretation, using custom-designed results criteria, is supported by a colour-coded data quality display. Zetasizer APS allows the production of large amounts of high quality DLS data with no user intervention to maximize productivity in busy protein laboratories. The data display capability enables the operator to easily retrieve results of interest, without having to manually scan through all measurements...

 

  Coriolis Pharma is first CRO in the world to routinely use Archimedes from Malvern Instruments

Team also publishes paper examining ability to distinguish between protein aggregates and oil droplets in biopharmaceutical formulations

ArchimedesCoriolis Pharma (Martinsried, Germany) has become the first pharmaceutical contract research organization in the world to routinely use Archimedes, a new analytical instrument supplied by Malvern Instruments. Coriolis Pharma specializes in formulation development for biopharmaceuticals such as proteins, peptides and vaccines and offers a wide variety of services to support product development....

 

  Dr Alan Rawle of Malvern Instruments is now Fellow of The Royal Society of Chemistry

Long time Malvern Instruments team member Dr Alan Rawle was recently admitted as a Fellow of the Royal Society of Chemistry (FRSC).

Dr Alan Rawle, FRSCDr Rawle has worked extensively with laser diffraction and other particle characterization techniques for more than two decades and the RSC fellowship recognizes his services to chemistry and continued contribution to analytical science.Based primarily in the US and serving as Malvern’s Divisional Applications Manager, Dr Rawle is currently on a six-month secondment to Malvern’s global headquarters in the UK...

 

  Malvern Instruments’ CTO will discuss new technology for characterizing protein formulations at International BioAnalytical Congress

Dr E Neil Lewis, Chief Technology Officer at Malvern Instruments and Head of the company’s Bioscience Development Initiative, will speak at the International BioAnalytical Congress taking place in Berlin (Germany) on 11 and 12 September 2013.

Viscosizer 200The theme of the conference is the future of bioanalytical development and Dr Lewis will discuss ‘Advances in the integrated measurements of higher order proteins’, focusing especially on new technology that combines dynamic light scattering with Raman spectroscopy. He will examine this as a means of providing structural, thermodynamic and kinetic insights into mechanisms of protein aggregation and the factors that influence protein stability. Malvern is pleased also to be a sponsor and exhibitor at the Congress....

 

  Conference presentation confirms mutual benefits of Malvern Instruments ‘Open Innovation’ strategy

A presentation by technology specialist Dr Richard Tweedie, given as part of the recent UK Formulation Showcase at NanoFormulation 2013 (18-21 June 2013, University of Manchester, UK), illustrated the mutual benefits of an ‘open innovation’ approach to product development.

Mastersizer 3000 laser diffraction particle size analyzer His talk focused on the ‘open innovation’ pathway adopted by Malvern Instruments in collaboration with The University of Leeds in the UK to develop the Aero S, one of the key sample dispersion systems for Malvern’s Mastersizer 3000 laser diffraction particle size analyzer. The Aero S dry powder disperser was launched alongside the Mastersizer 3000 in September 2011 and immediately delivered new capabilities to laser diffraction users, extending dry powder dispersion to even the most fragile materials...

 

  Malvern Instruments highlights new analytical instruments for biopharma at The Bioprocessing Summit

Malvern Instruments is showcasing new analytical tools for biopharmaceutical applications on its exhibition booth at The Bioprocessing Summit in Boston

Viscotek SEC-MALS 20In July the company launched two new systems, the Viscotek SEC-MALS 20 and the Viscosizer 200, for the characterization of biological materials. These join Malvern’s rapidly growing range of analytical instruments, which also includes the Zetasizer Nano ZSP, for use in pre-formulation and formulation studies and for the wider characterization of proteins and other macromolecules.....

 

  Malvern Instruments adds ‘Suspension Properties’ series to its highly popular online Masterclasses

Malvern Instruments has kicked off a brand new series of Masterclass webinars available both as live events and subsequently as recorded presentations.

Malvern Masterclass webinars Particle size and sitributionBased on the company’s established Masterclass concept, the ‘Masterclass on Suspension Properties’ series guides participants on how to use rheology in combination with other analytical techniques in order to formulate suspensions to meet specific performance targets. The information is delivered in a very straightforward style, making the subject easily accessible and comprehensible to the broadest of audiences...

 

  Malvern Instruments launches Viscotek SEC-MALS 20 – a new choice of GPC/SEC light scattering detector

The launch of the Viscotek SEC-MALS 20 brings new standards of performance and greater choice in gel permeation/size exclusion chromatography (GPC/SEC) and extends the Malvern Instruments family of light scattering detectors for measuring the absolute molecular weight of proteins, macromolecules and polymers.

Malvern’s Viscotek range now includes cost-effective options with unsurpassed performance for every type of light scattering detection – low angle, right angle and multi angle – allowing Malvern to answer every GPC/SEC challenge with the most appropriate technology. With this extension to its detectors range, Malvern becomes the only vendor to offer all light scattering options....

 

  Surface Zeta Potential Cell eliminates need for dedicated instrument

A series of  new application notes posted on the Malvern Instruments website describes the quick and easy measurement of surface zeta potential using the zeta potential planar cell for the Zetasizer Nano particle characterization system.

Surface Zeta PotentialWidely used as an indicator of the stability of particle suspensions and colloidal samples, surface zeta potential is traditionally measured using the specialist technique of streaming potential. Malvern’s Surface Zeta Potential Cell eliminates the need for a dedicated solution, allowing users to measure the zeta potential of surfaces in an aqueous medium on a standard instrument. The application note ‘Determination of the zeta potential of the surface of PTFE’, and others relating to different aspects of the measurement, can now be downloaded from Malvern’s online knowledge center...

 

  Malvern Instruments’ new ‘Introduction to Static Light Scattering’ white paper available free online

Malvern Instruments has published ‘Static Light Scattering Technologies For GPC/SEC Explained’, a valuable guide for anyone assessing the value of a light scattering detector for gel permeation/size exclusion chromatography (GPC/SEC).

Static light scattering delivers absolute molecular weight measurementCovering the theory and practice of molecular weight measurements using static light scattering, this basic guide serves as both an introduction for those with no prior knowledge of the technique and a reference document for anyone looking to enhance their understanding. The white paper is available as a free download from the Malvern Instruments website

 

  Surface Zeta Potential Cell eliminates need for dedicated instrument – new Malvern application notes

A series of  new application notes posted on the Malvern Instruments website describes the quick and easy measurement of surface zeta potential using the zeta potential planar cell for the Zetasizer Nano particle characterization system.

Malvern Instruments Surface Zeta Potential CellWidely used as an indicator of the stability of particle suspensions and colloidal samples, surface zeta potential is traditionally measured using the specialist technique of streaming potential. Malvern’s Surface Zeta Potential Cell eliminates the need for a dedicated solution, allowing users to measure the zeta potential of surfaces in an aqueous medium on a standard instrument....

 

  Cemtec integrates Insitec sensors from Malvern Instruments for efficient mill monitoring and control

Cemtec (Enns, Austria) a specialist provider of grinding technologies for the mining, mineral and cement industries, is using Insitec real-time particle sizing technology from Malvern Instruments to provide fully integrated, automated milling solutions that deliver high efficiency at competitive cost.

Malvern, Cemtec intergrationAn exchange of equipment, between the two companies, has led to the installation of an Insitec system for the control of dry milling at Cemtec’s extensive pilot plant facility and now customers of both companies can see for themselves how real-time particle sizing can transform process performance. “Increasingly customers are looking for us to provide turnkey, often automated, milling circuits, rather than a stand alone mill,” said Mr Plochberger, Head of R&D and Process Technology at Cemtec...

 

  Kingston University researchers acknowledge Malvern GPC contribution to new polymer research paper

In a new paper published in Polymers & Polymer Composites (Vol 21, No 1, 2013), researchers at Kingston University in the UK report the results of continuing work to examine the effects of gamma irradiation on intraocular lenses (IOLs) used in cataract surgery. Triple detection gel permeation chromatography (GPC) using the Viscotek TDAmax system from Malvern Instruments was a key analytical tool in this work.

Kingston UniversityBaljit Ghatora and co-authors examined medical grade poly(methyl methacrylate) (PMMA), which is used especially widely in developing countries to make rigid intraocular lenses and for which low cost, convenient gamma irradiation is increasingly the preferred method for sterilisation. Previous reports have suggested that gamma irradiation has the potential to alter the structural features of the polymer, such as molecular weight and molecular size distribution, which in turn may impact the efficacy and performance of IOLs....

 

  Viscometer detector from Malvern enhances GPC/SEC analysis for polymer development

For those working at the forefront of polymer development, adding a Malvern Viscotek viscometer detector into gel permeation/size exclusion chromatography (GPC/SEC) set ups can help deliver the enhanced information need to achieve challenging performance specifications. 

MAL JOB 2703_ImageStudies with evolving commercial polymers, such as polymethylmethacrylate (PMMA) and polylactic acid (PLA), show how the structural information revealed by measuring viscosity parameters enables researchers to intelligently modify polymer chain length and branching to meet precise goals. Malvern Viscotek viscometers can be supplied as part of an integrated triple detector Viscotek GPC/SEC system or as an addition to any existing separation system....

 

  Malvern Instruments wins decisive victory over Wyatt Technology Corporation in US Court of Appeals

US Court of Appeals characterizes Wyatt Technology Corporation Lanham Act claims as “groundless, unreasonable, vexatious or pursued in bad faith”

Malvern InstrumentsMalvern Instruments Inc. has scored a decisive win in the final round of a long-running court battle waged by Wyatt Technology Corporation regarding the sale of Malvern’s Zetasizer Nano range in the US. Wyatt had alleged copyright infringement of software and other materials, false advertising and theft of trade secrets, and sought damages from Malvern in excess of $25 million (USD). However, Wyatt has ended up having to reimburse Malvern more than $2 million (USD) in respect of attorneys’ fees and costs.

 

  Malvern Instruments announces global agreement with Proveris Scientific

Malvern Instruments, a leader in the field of pharmaceutical material characterization, has announced a global agreement with Proveris Scientific Corporation, a company with complementary technology for orally inhaled and nasal drug product (OINDP) testing, to provide a complete solution for nasal spray characterization....

SpraytecThis solution comprises the SoloTM for Spraytec system (Proveris), a high performance patented automated actuator and software for the precise control of the actuation profile applied during device testing, and the Spraytec laser diffraction particle size analyzer (Malvern), which measures the evolution of particle size in real-time during a spray event. In combination these technologies support the efficient optimization of nasal spray devices and formulations, and enable robust investigation of the parameters which may impact drug delivery....

 

  Malvern Instruments and NETZSCH Grinding & Dispersing sign agreement to cooperate

Materials and biophysical characterization company Malvern Instruments Ltd and NETZSCH Grinding & Dispersing a worldwide manufacturer of industrial wet and dry grinding, mixing, dispersing and kneading equipment, have entered into a cooperative marketing agreement.

Powtech 2013Both organizations serve a broad range of market sectors from pharmaceuticals, ceramics, nano-technology applications, food and surface coatings through to mining metals and minerals. The global agreement, initially in place for three years, will harness the strength of each company’s world-leading brands and unique expertise in materials processing and materials characterization. Under the terms of the agreement NETZSCH will standardize on Malvern’s particle sizing and characterization equipment, primarily the Mastersizer 3000 laser diffraction particle size analyzer...

 

  Malvern Instruments to sponsor 8th Annual European Rheology Conference

Malvern Instruments, a company keen to share its  new technology for microrheology, is sponsoring the 8th Annual European Rheology Conference which takes place  in Leuven, Belgium, 2nd to 5th April 2013

Malvern Instruments Zetasizer Nano ZSPExpert rheologists from Malvern will be in attendance throughout the event, and on display will be the Kinexus, a high performance rotational rheometer that enables advanced shear and vertical testing, and the Zetasizer Nano ZSP, a premium light scattering system with microrheology capability.The conference brings together leading rheologists from around the world for four days of lectures and seminars. Microrheology, a relatively new technique, is sure to be a popular topic for discussion...

 

  EMBL Hamburg researchers use Viscotek TDA for enhanced protein characterization by SAXS

Researchers at the European Molecular Biology Laboratory (EMBL) in Hamburg, Germany,  have incorporated a multi-detector array size exclusion chromatography (SEC) system from Malvern Instruments (Viscotek TDA –Triple Detector Array) at the laboratory’s powerful small angle X-ray scattering (SAXS) beamline to improve the productivity and quality of detailed protein characterization work

The Viscotek TDA at Hamburg EMBL is used to enhance protein characterization by SAXS.Use of the Viscotek TDA triple detector array system prior to analysis provides complementary biophysical data and simultaneously purifies samples for measurement. This results in more information and better quality data from each experiment. This innovative set-up is not only limited to the institute itself, but  is widely accessible to structural biology researchers via BioStructX, a European Commission initiative that creates a single gateway to Europe’s leading synchrotron facilities...

 

  Visit Malvern Instruments at Powtech: new material characterization products and expert advice - Hall 1/1-357

Leading technologists from Malvern Instruments, the materials characterization experts, will be presenting at Powtech

The Mastersizer 3000Dr Alan Rawle, a highly-respected figure in the field of light scattering will present “Attrition of FCC catalysts studied by pressure size titration (PST) in laser diffraction dry dispersion” while Dr Debbie Huck, an authority on imaging, will present “Component specific particle characterization of particulate-based products.” Look out too for live instrument demos throughout the 3 days and networking events around Partec...

 

  Malvern launches new Imaging Masterclass webinar series

Malvern Instruments’ new series of web-based Imaging Masterclasses kicks off on 26 February 2013 with an introduction to imaging for particle characterization

Malvern Masterclass series on Imaging for particle characterizationThe series will then continue through the year and will cover a broad range of imaging topics. Alongside this will run the laser diffraction Masterclass series which will discuss subjects including wet method development, dry method development, optical property selection and specification setting...

 

  Morphologically directed Raman spectroscopy supports identification of particles in mixed populations

With the introduction of the Morphologi G3-ID system last year, Malvern Instruments is providing researchers with the ability to apply morphologically directed Raman spectroscopy to a range of different sample types

Morphologi G3-ID systemSuch advanced particle analysis is proving valuable and highly effective in applications that include inhaled product characterization and pharmaceutical bioequivalence studies, bioequivalence for nasal sprays being referenced specifically in a talk given by the FDA at this year’s IFPAC conference [January 22-25, 2013 Baltimore, MD, USA]. The use of morphologically targeted Raman spectroscopy has also been described in an independent article, as part of granulation studies, to provide the physical and chemical identities of particles in mixed populations [1]...

 

  New brochure shows Zetasizer Nano versatility for colloid, protein and nanoparticle characterization

Following the recent launch of the top-of-the-range Zetasizer Nano ZSP system, Malvern Instruments has published a new brochure that helps potential purchasers select the right Zetasizer Nano dynamic light scattering system for their specific colloid, nanoparticle or macromolecule application

Zetasizer Nano dynamic light scattering system brochureThe new brochure provides an introduction to dynamic light scattering, zeta potential, protein mobility and protein charge, molecular weight measurement and microrheology, as well as full details and technical specifications for Malvern’s complete family of Zetasizer Nano systems. These range from high end instruments that incorporate non-invasive back scatter (NIBS) optics, to the affordable 90-degree scattering system...

 

  Malvern brings new perspectives to protein aggregate detection at PepTalk 2013

In a session devoted to protein aggregation and emerging analytical tools at this year’s PepTalk conference, Dr E. Neil Lewis, Chief Technology Officer for Malvern Instruments, will discuss ‘Recent advances in the integrated measurements of size, high order structure and formulation viscosity of biopharmaceutical formulations’

Zetasizer Nano ZSP from MalvernThe paper he will present is co-authored by Dr Kevin Mattison, Principal Scientist, Bioanalytics, at Malvern, who will also be one of the instructors leading Malvern’s Dinner Short Course: ‘How to obtain reliable information from light scattering: theory, practical advice and data interpretation’.

 

  New data shows value of morphologically directed Raman spectroscopy for bioequivalence studies

A new application note on the Malvern Instruments website describes the use of morphologically directed Raman microscopy in assessing the bioequivalence of a generic and innovator drug with a dual active pharmaceutical ingredient (API)

Overlay of particle size distributions for generic and innovatorThe work was carried out using the Morphologi G3-ID, which combines automated image analysis with Raman spectroscopy. The Morphologi G3-ID enables the determination of component-specific particle size distributions, which in this study were important because of  the effects of particle size on tablet disintegration and subsequent bioavailability. ‘Generic versus Innovator: an In-Vitro Bioequivalence Study with the G3-ID’ is freely available as a download from the Malvern website....

 

  Mastersizer 3000 shows multi-parameter capabilities for catalyst optimization

New application note discusses particle sizing, specific surface area and predicting attrition rate in fluidized beds

Pressure titration for three different catalystsA new application note on the Malvern Instruments’ website discusses the criticality of particle size in the development and production of heterogeneous catalyst materials, and presents data to demonstrate the utility of the Mastersizer 3000 particle size analyzer in achieving optimum reactivity...

 

  Hiroshima University is first to install Malvern Instruments’ new Zetasizer Nano ZSP

Dr Kikuo Okuyama of the Department of Chemical Engineering at the Graduate School of Engineering, Hiroshima University in Japan, was the first customer to take delivery of a Zetasizer Nano ZSP, the new top-of-the-range dynamic light scattering system from Malvern Instruments

Graduate students at the Department of Chemical Engineering at the Graduate School of EngineeringIn Dr Okuyama’s work the objective is to find alternative materials for rare earths and to develop rare earth-free functional materials. This involves research into the composition and structure of functional fine particles and will use the Zetasizer Nano ZSP in the evaluation of nano particle size, dispersion and surface chemistry...

 

  Malvern’s complementary detector arrays boost GPC/SEC productivity

Apply both dynamic and static light scattering for size and molecular weight measurement

Zetasizer ”V, a versatile size and molecular weight detectorMalvern Instruments’ detector range for gel permeation/size exclusion chromatography (GPC/SEC) now includes the Zetasizer ”V, a versatile size and molecular weight detector that can be added to any system to boost experimental productivity by maximizing information flow from a single experiment. Complementary to Malvern’s established Viscotek range, which includes detectors for concentration, intrinsic viscosity and absolute molecular weight measurement, the Zetasizer ”V is a dual integrated light scattering system with particular value for protein characterization...

 

  Zetasizer Nano ZSP helps users meet new zeta potential measurement standard for biologics

One of the most significant applications for Malvern Instruments’ new Zetasizer Nano ZSP dynamic light scattering system is the highly sensitive measurement of the zeta potential, or electrophoretic mobility, of proteins

Zetasizer Nano ZSP dynamic light scattering systemThe instrument delivers unique performance specifications for both size and zeta potential measurement, employing an approach to zeta potential measurement that accords with the latest industry guidance. Published during 2012, standard guide ASTM E2865 deals with the measurement of mobility and zeta potential in systems containing biological material such as proteins, DNA, liposomes and other similar organic materials that possess particle sizes in the nanometer scale, below 100 nm...

 

  Malvern Instruments to showcase new instrument for OINDP characterization at DDL23

Malvern Instruments will showcase the new Morphologi G3-ID particle characterization system at Drug Delivery to the Lungs 23, which takes place from 5 – 7 Dec 2012 in Edinburgh, Scotland

Morphologi G3-ID particle characterization systemThe company will highlight the system’s ability to generate component-specific particle size and shape data that efficiently support the commercialization of both new and generic Orally Inhaled and Nasal Dry Products (OINDPs). Activities at the conference will include a poster presentation that details results from a new study in which the Morphologi G3-ID was used to successfully measure nasal sprays in the formulated liquid state with minimal sample preparation...

 

  Exclusive agreement to distribute Affinity Biosensors’ Archimedes system extends Malvern Instruments’ biopharma solutions

Materials characterization company Malvern Instruments Ltd. (Malvern, UK) has signed an exclusive distribution agreement with Affinity Biosensors LLC (Santa Barbara, CA, USA) which will extend the range of solutions that Malvern offers to the biopharmaceutical sector. The distribution agreement covers all geographies outside the USA and Canada

Archimedes systemUnder the terms of the agreement Malvern will distribute the Archimedes Particle Metrology system, developed and manufactured by Affinity Biosensors, through its subsidiaries in Europe and Asia. Malvern will establish a co-marketing arrangement with Affinity Biosensors in North America...

 

  Malvern Instruments and Novozymes Biopharma publish collaborative study using light scattering techniques to support formulation development

In a recently published article, researchers from Novozymes Biopharma (Nottingham, UK) and Malvern Instruments (Malvern, UK) describe collaborative work using light scattering techniques to demonstrate the short- and long-term stability of the novel recombinant human albumins AlbucultÂź and RecombuminÂź

Malvern Zetasizer systemsThese rAlbumins have been developed and optimized to deliver a safe, stable and regulatory-compliant product for therapeutic formulations. The teams applied the resolving and detection capabilities of size exclusion chromatography light scattering (SEC-LS) and dynamic light scattering (DLS) offered by Malvern systems to monitor the stability of these Novozymes products. The article ‘Tools for evaluating the stability of human recombinant albumins used in human therapeutics’ can be accessed at...

 

  Malvern Instruments & Malvern St James Girls’ School encourage girls into science and engineering

Malvern Instruments, a leading provider of scientific instruments for materials characterization, kicked off a scientific discovery programme with a presentation to Malvern St James Girls’ School in Worcestershire to encourage students into a career in science or engineering

Malvern St James Girls’ School The House of Lords Science and Technology Committee back in July 2012 called for immediate action to be taken to ensure that enough young people study Science, Technology, Engineering and Maths (STEM) subjects at school, in further education and postgraduate level. In order for UK technology companies to remain competitive and to continue to bring innovative R&D products to the market place, the next generation of students need to be inspired and be educated within STEM subjects to maintain current levels of economic growth in this sector in the future...

 

  Malvern Instruments introduces DLS Microrheology

New Zetasizer Nano ZSP offers emerging rheology technique for weakly structured fluids

An Introduction to DLS MicrorheologyWith the recent launch of the new top of the range Zetasizer Nano ZSP system, Malvern Instruments has added dynamic light scattering (DLS) Microrheology to its portfolio of materials characterization techniques. To introduce this powerful technique, the company has published an in-depth paper that explains the background to microrheology, and how it can be used to investigate the rheological properties of even the most weakly structured fluids, using sample volumes on the microliter scale. ‘An Introduction to DLS Microrheology’ includes data for protein (bovine serum albumin (BSA)) and polyethylene oxide (PEO) solutions that illustrate the significance and usefulness of the method. It is freely available from the Malvern website.

 

  Malvern Instruments launches Morphologi G3-ID to global markets

Following the completion of a highly successful early access program, Malvern Instruments has launched the Morphologi G3-ID particle characterization system to the global market

Morphologi G3-ID particle characterization system A live webinar on 2 October 2012 introduced participants to the unique capabilities of the system, which combines automated particle imaging with the chemical identification of individual particles using Raman spectroscopy. This fully automated system measures particle size, shape and chemical identity in a single platform...

 

  Moving laser diffraction from the laboratory into the production process

In a new presentation from Malvern Instruments entitled ‘Moving laser diffraction from the laboratory into the production process’, Product Group Manager Dr. Paul Kippax discusses the benefits and challenges of taking laboratory-based particle sizing out into the production process

Moving laser diffraction from the laboratory into the production processThe presentation is particularly tailored to the pharmaceutical industry but is generally relevant to all manufacturers considering an investment in on-plant real-time particle size measurement and can be freely downloaded...

 

  Malvern launches the Zetasizer Nano ZSP to global audience

On 12 September 2012 Malvern Instruments conducted the global launch of an exciting addition to its Zetasizer family, bringing unique protein measurement and novel microrheology capabilities to this established and market-leading range of dynamic light scattering (DLS) systems

The new Zetasizer Nano ZSP from Malvern Introduced in the space of 24 hours, via a series of webcasts, to audiences around the world, the new high specification Zetasizer Nano ZSP delivers enhanced sensitivity and comes with advanced software that drives the two new measurement types. Like other systems in the range, the Zetasizer Nano ZSP is a single, compact unit. It shares the simplicity and ease of use that have made Zetasizer Nano systems a firm favourite in industry and academia for almost a decade. Where the Zetasizer Nano ZSP stands apart, however, is in its unique performance specifications for both size and zeta potential measurement...

 

  A breakthrough in Nylon characterization from Malvern Instruments

A novel gel permeation chromatography (GPC) method for characterizing Nylon, developed by researchers at Malvern Instruments, significantly reduces the cost of analysis while simultaneously improving safety, when compared with conventional techniques

Nylon molecular modelThe new method uses formic acid as a solvent for Nylon, in place of the traditional choice of hexafluoroisopropanol (HFIPA), a relatively expensive, aggressively corrosive solvent with poor health and safety characteristics. First presented at a recent webinar by Dr Wei Sen Wong, his breakthrough is expected to generate significant industrial interest...

 

  Malvern Zetasizer Nano is integral to Queen’s University’s polymer characterization lab

"The Zetasizer Nano ZS is an integral piece of equipment in our polymer characterization laboratory," said Daniel Krasznai, Department of Chemical Engineering, Queen's University, Kingston, Canada. "The most important features that the Zetasizer Nano ZS offers are rapidity, reproducibility, and a user-friendly interface."

The Zetasizer Nano from Malvern InstrumentsDaniel Krasznai's supervisor, Dr. Michael F. Cunningham, holds the Ontario Research Chair in Green Chemistry and Engineering at Queen's University. His team focuses on the synthesis of polymer colloids using a range of dispersed free-radical polymerization techniques. Together with Dr. Niels M.B. Smeets, and fellow collaborators Dr. Pascale Champagne and Dr. Timothy F.L. McKenna, they have recently published a paper in which they use the Zetasizer Nano ZS to characterize novel core-shell materials in pure water.

 

  New data confirm Mastersizer 3000 is breaking new ground in dry powder particle sizing

New experimental data published by Malvern Instruments illustrate the real-world capability and flexibility of the Mastersizer 3000 laser diffraction system for the particle size measurement of dry powders

Mastersizer 3000 with Aero S dry dispersion unitEquipped with the unique Aero S dry dispersion unit, the Mastersizer 3000 breaks new ground in dry powder particle sizing and experimental results are described in "Extending the boundaries of laser diffraction measurements: Enhanced dry dispersion with the Aero S" , a new publication on the Malvern website.

 

  Malvern Spraytec used in characterizing agricultural spray nozzles A new application note from Malvern Instruments discusses  the importance of droplet size in agricultural spraying and describes the use of the company's Spraytec system in defining the performance of agrochemical application systems. 

Droplet size is important for effective agrochemical spray applications‘Characterization of agricultural spray nozzles using the Malvern Spraytec' provides insight into the way this laser diffraction droplet size analyzer helps in understanding the performance of spray nozzles used for the application of herbicides, fungicides and insecticides.

 

  Zetasizer Nano delivers essential data in environmental nanosafety work in Canada Researchers at the University of Alberta, Canada, working as part of a major Canadian initiative to investigate the aquatic and environmental aspects of nanoparticles, are using the Zetasizer Nano from Malvern Instruments to characterize nanoparticle behavior in biological and aqueous matrices.

Mr Van OrtegaSize is known to affect nanoparticle toxicity and toxicology and the technique of dynamic light scattering (DLS) provides the average size behavior in solution. As implemented in the Zetasizer Nano, it delivers information for physical characterization in terms of charge and solubility...

 

  Malvern’s Viscotek makes HT-GPC safer at Jordi Labs LLC According to Dr Mark Jordi, President at Jordi Labs LLC, the online filtration capability offered by Viscotek high temperature gel permeation chromatography (HT-GPC) systems from Malvern Instruments has removed the need for dangerous and difficult manual filtration during high temperature polymer analysis.

The Viscotek HT-GPC system in situ at Jordi Labs LLC"GPC is an integral part of Jordi Labs' analytical capabilities," said Dr Jordi. "The Viscotek systems provide a richness of information not obtained with other instruments. The online filter for the high temperature GPC instruments works well. We previously performed this manually and it was both dangerous and difficult. Online high temperature filtration is a big improvement."...

 

  New advice from Malvern Instruments for implementing on-line particle size analysis A new white paper from Malvern Instruments examines the different strategies open to anyone adopting on-line particle size analysis, providing guidance on its design and implementation and highlighting the economic and practical benefits of selecting an approach best suited to the project in hand.

on-line particle size analysisThe white paper discusses the choices around project implementation, advises on how to take best advantage of in-house expertise and suggests when to draw on outside help. ‘Strategies for success: How will you implement on-line particle sizing? Choosing the right approach' is available for download...

 

  Johns Hopkins experience shows Malvern customers buy more than just an instrument Zetasizer Nano Justin Galloway, a graduate member of the Searson and Devreotes Group at The Johns Hopkins University in the Institute of NanoBioTechnology (Maryland, USA), cites Malvern Instruments customer support as being instrumental in helping interpret and develop some of the data associated with the publication of a paper in the journal Nanomedicine...

 

  Back to basics with Malvern Instruments particle characterization white paper A basic guide to particle characterizationFrom a starting point of ‘what is a particle?', Malvern Instruments' new ‘A basic guide to particle characterization' white paper  takes the reader through descriptions of a range of particle properties and then goes on to introduce a variety of different particle characterization techniques. Designed both as a primer for those new to particle characterization and as a refresher for the more experienced...

 

  Malvern presenter at ISPAC 2012 aims to answer the challenges of biopolymer characterization Malvern Viscotek TDAmax multi-detector GPCSeparations expert Bert Postma from Malvern Instruments will talk about the challenges of biopolymer characterization  at the International Symposium on Polymer Analysis and Characterization 2012 (ISPAC) being held in Kerkrade, The Netherlands, June 10-12, 2012. Malvern is also a sponsor and exhibitor at the event.  The company offers a wide range of  instrumentation for characterizing many different types of polymer, enabling the rapid generation of information on molecular weight, molecular weight distribution, branching, conformation, rheological properties, morphology and particle size...

 

  Malvern’s new white paper provides expert guidance for rheological measurement of yield stress A performance-defining parameter in products from paint and coatings to personal care

measurement of yield stressA new white paper from Malvern Instruments is aimed at helping product developers and formulators get to grips with the measurement of yield stress. Yield stress is a rheological parameter that is industrially important in defining the performance of food, paint, personal care and many other products. In order to obtain relevant, robust and reproducible yield stress data for a particular material, it is essential to make an assessment of both the test type, and the measurement protocol used to perform the test. The white paper ‘Understanding yield stress measurements' provides a valuable introduction to the topic...

 

  Malvern team presents ‘Nanoparticle characterization by light scattering’ poster at ACS Colloids 2012 symposium Nanoparticle characterization by light scatteringMalvern Instruments light scattering specialists Dr Ana Morfesis and Dr Ulf Nobbmann, will present a poster on ‘Nanoparticle characterization by light scattering' as part of the 86th ACS Colloid and Surface Science Symposium being held at the University of Baltimore in Maryland,  USA, June 10-13, 2012. Their poster will be displayed from 5.30 until 7.30 pm on Monday June 11 in a session held in the exhibition area, where delegates will also be able to visit the Malvern booth to find out more about the company's full range of systems for nanoparticle characterization, including the market leading Zetasizer Nano.

 

  Protein mobility using laser Doppler electrophoresis at IACIS 2012 Protein mobility using laser Doppler electrophoresisRobert Jack, Principal Scientist at Malvern Instruments is to speak at the upcoming IACIS 2012 (International Association of Colloid and Interface Scientists) Conference held over 13-18 May at the Sendai International Centre in Japan. His talk is titled ‘Non-electrode contact colloid and protein mobility using laser Doppler electrophoresis - the diffusion barrier technique'. It will take place at 10:45 on Thursday 17 May and covers a novel technique developed by Malvern Instruments for the measurement of protein mobility using laser Doppler electrophoresis...

 

  New Malvern download with detailed Zetasizer specifications helps users match system with application Malvern Zetasizer particle characterization systemsIn line with a policy of continuous improvement, Malvern Instruments has reviewed, verified and published updated specifications for the Zetasizer series of dynamic light scattering (DLS) particle characterization systems, all fully backed by measurements on real samples. Full updated specification details are available online...

 

  Malvern particle characterization systems supporting inhaled drug development at RDD 2012 Malvern Mastersizer 3000Particle size is a critical parameter for inhaled drugs, with a defining influence on deposition behavior in the lung. Particle characterization specialists Joe Wolfgang and Julie Chen from Malvern Instruments will be on hand to discuss these issues at the Respiratory Drug Delivery conference (RDD 2012) in Phoenix, Arizona, May 13-17, where Malvern will showcase the recently launched  Mastersizer 3000 particle size analyzer...

 

  Mastersizer 3000 wins best new instrument award in China Malvern Instruments' Mastersizer 3000 Malvern Instruments' Mastersizer 3000 laser diffraction particle size analyzer has been awarded ‘Best New Instrument of the Year 2011' by the Annual Conference of China Scientific Instruments 2012 (ACCSI 2012) held in March 2012 in Beijing. A total of 533 new instruments from 257 companies were proposed for the award and the Mastersizer 3000, which was launched in September 2011, was one of only 23 new instruments declared winners...

 

  Malvern foundations in rheology web seminars now available in eight languages Malvern RheologyIn support of expanding global demand, materials characterization company Malvern Instruments is rapidly increasing its provision of multilanguage webcasts. In the latest posting, researchers across the world can now download a two-part foundation presentation covering rheology principles and applications, in eight different languages...

 

  Malvern refocuses laser diffraction masterclasses to include new Mastersizer 3000 Mastersizer 3000Malvern Instruments has refocused its popular Mastersizer Masterclass webinars to encourage exploitation of the full potential of the new Mastersizer 3000. The Mastersizer Masterclass series provides all the information required to apply best practice and get the most from laser diffraction measurements. The course is open to all laser diffraction users, whether or not they are Malvern customers...

 

  Malvern experts contribute to University of Leeds ‘Fundamentals of formulation course’ for colloid and interface scientists Fundamentals of Formulation Science and Technology coarseMalvern Instruments technical experts, Dr Stephen Ward-Smith and Martina Pfau, will contribute to the inaugural ‘Fundamentals of Formulation Science and Technology' course. Beginning on Monday 28 May 2012 at the University of Leeds (UK) and spanning three days, this course is aimed at industry personnel and academic researchers and will deliver a broad overview of the fundamentals of formulation. According to its hosts, Intelligent Formulation Ltd and ParticlesCIC, course presenters have been selected for their distinguished record in practical industrial applications of formulation science and technology...

 

  How to measure polymer solution viscosity safely The Viscotek Dilute Solution Viscometry (DSV) systemA new recorded presentation from Malvern Instruments compares the use of Dilute Solution Viscometry (DSV) with that of traditional glassware for measuring polymer intrinsic viscosity. Intrinsic viscosity correlates directly with molecular weight, which is a critical variable for polymers due to its controlling influence on processability and the mechanical properties of the final product. Intrinsic viscosity is therefore used as part of the specification for many commodity and engineering polymers...

 

  Coffee break! Malvern on-line particle sizing helps De'Longhi achieve 100% testing of each ‘bean to cup’ coffee maker Insitec particle size analyzer Renowned globally for the quality of its coffee makers, manufacturer De'Longhi has transformed  QC processes for grinders at its manufacturing facility in Mignagola di Carbonera, using the Insitec on-line particle size analyzer from Malvern Instruments. The Malvern applications team worked closely with engineers at De'Longhi to develop a fully automated solution that supports the target of achieving 100% testing, of every element, of each ‘bean to cup' coffee maker. Grinder set-up is assessed on the assembly line by analyzing the particle size of freshly ground coffee beans...

 

  A trio of Malvern characterization tools measures up for food science Researchers at the Department of Food ScienceArmed with a Zetasizer Nano, a Mastersizer 2000 particle size analyzer, and a Kinexus rheometer, Professor David Julian McClements and his team of researchers at the Department of Food Science, University of Massachusetts (UMass), Amherst, USA, have developed a recipe for success in the development of foods. This trio of characterization tools from Malvern Instruments has enabled the UMass team to develop a variety of improved and novel colloidal delivery systems for food and pharmaceutical applications, including microemulsions, nanoemulsions, multilayered emulsions, solid lipid nanoparticles, and hydrogel particles...

 

  Malvern Instruments opens new multipurpose facility in Houston Malvern Instruments new multipurpose facility in HoustonOn 19 March 2012, and just one week after moving in, materials characterization company Malvern Instruments has officially opened a new multipurpose facility in Houston, Texas. At 22,000 sq. ft. the new building is double the size of Malvern’s previous premises in Houston and houses state-of-the-art laboratories, product development, manufacturing and commercial operations. The site will be a Center of Excellence for the company’s separations products, as well as providing applications development and demonstration facilities for all Malvern systems...

 

  Malvern team will lead light scattering workshop at PEGS summit Malvern Instruments Zetasizer Nano SystemDrs Kevin Mattison, Ulf Nobbmann and Jean-Luc Brousseau of Malvern Instruments will lead a workshop on ‘Light Scattering – Theory, Do’s & Don’ts, and Data Interpretation’ at the 8th Annual PEGS - Protein & Antibody Engineering Summit, which takes place in Boston MA, from April 30 - May 4, 2012...

 

  Join Malvern’s April seminars around the UK

Malvern InstrumentsJoin one of Malvern Instruments UK seminars in April and learn how to develop better products by understanding the size, shape, chemistry and rheological behaviour of materials.  These one-day events, which combine expert presentations with hands-on sessions, are taking place in Newport (17 April), Ascot (18 April), Stirling (25 April) and Bradford (26 April)...

 

  Mastersizer 3000 particle size analyzer makes Analytica debut Mastersizer 3000 particle size analyzerMalvern Instruments' new Mastersizer 3000 laser diffraction particle size analyzer will make its Analytica debut on Stand No A1.320 (April 17-20, Munich). This state-of-the-art, small footprint instrument is designed for smart particle sizing, delivering precise, high-resolution wet and dry sample measurement from 10 nm to 3.5 mm. New sample dispersion units provide a solution for every application, including the dry dispersion of fragile particles, while simple intuitive software drives user-defined measurements and simplifies method development.... 

 

  Lessons in sizing up surface science Malvern Zetasizer Nano Associate Professor Albena Ivanisevic and her team in the Department of Materials Science and Engineering at North Carolina State University (US) are so pleased with results from the department's Zetasizer Nano particle characterization system that they have purchased two further instruments for teaching purposes. Part of the Malvern Instruments materials characterization portfolio, the Zetasizer Nano light scattering system has a reputation for ease-of-use, robust performance, and low maintenance, making it the ideal tool for use in multi-application, multi-user environments and for educating newcomers in the science of particle characterization....

 

  Smart approach to method development as new Mastersizer 3000 takes ‘ease of use’ to new levels Mastersizer 3000 particle size analyzerReflecting the wealth of engineering and applications expertise at Malvern Instruments, the company's new Mastersizer 3000 particle size analyzer takes performance and ease of use to the highest level. This new system wraps groundbreaking optical capabilities with software that supports the user every step of the way - from method development right through to routine measurement - helping operators at every level to gather appropriate, reliable and reproducible data...

 

  Malvern Instruments commits to extensive program of free educational webinars in 2012 Malvern Instruments WebinarsWith more than 70 English language webinars scheduled for 2012, plus many presented in multiple languages, Malvern Instruments continues its commitment to the company's firmly established cultural premise that knowledge sharing has great benefits for all concerned. Now in its 11th year, Malvern's program of online web seminars includes a wide range of material characterization presentations, appropriate for beginners through to experts from a wide range of industries...

 

  Malvern specialist presents GPC/SEC benefits at Chromatographic Society meeting Malvern InstrumentsA separation technique specialist from Malvern Instruments will speak at the upcoming symposium ‘Chromatographic characterisation and purification techniques for Biopharm', a meeting with a packed programme of presentations and workshops that will focus on monoclonal antibody-derived drugs. This 2-day event is organised by the Chromatographic Society and will be hosted at the GlaxoSmithKline Medicines Research Centre in Stevenage, UK on 14/15 March 2012. Malvern is also one of the symposium sponsors...

 

  Malvern expert speaks on high temperature GPC at Texas polyolefins conference The Malvern Viscotek HT-GPC systemChromatography applications expert Wei Sen Wong from Malvern Instruments, will talk about the  practicalities of high temperature gel permeation chromatography (HT-GPC) at the Society of Plastics Engineers (SPE) Joint International Polyolefins/FlexPack Conference being held in Houston, Texas, February 26-29, 2012. Malvern Instruments is also an exhibitor at the event and will display their systems at Booth #40.

 

  Malvern Instruments and Postnova Analytics co-operate to deliver combined solution for characterizing challenging particulate systems Malvern Instruments and Postnova AnalyticsMalvern Instruments (Malvern, UK) and Postnova Analytics (Landsberg/Lech, Germany) have announced that they are co-operating to deliver the combined FFF (Field-Flow Fractionation) and DLS (Dynamic Light Scattering) solutions that today provide critical insight when characterizing a number of challenging particulate systems. Such systems include complex, aggregated, surface-coated and heterogeneous particles, as well as larger polymers, and aggregated, cross-linked, nano-particles and fibrillated proteins...

 

  ‘Smarter particle sizing’ on Malvern booth at Pittcon 2012 The new Mastersizer 3000 from MalvernMaterials characterization company Malvern Instruments focuses on ‘smarter particle sizing' as the Mastersizer 3000 laser diffraction particle size analyzer makes its Pittcon debut in 2012 (Booth #3641 Pittcon 2012, 11-15 Mar 2012, Orlando, FL). This small footprint instrument delivers precise high-resolution wet and dry sample measurement from 10 nm to 3.5 mm, with rapid operator-independent measurement enabling increased lab productivity...

 

  Four leading companies collaborate to deliver complete package ARTMiS – An automated real time micronization solution The results of a unique collaboration between four market leading companies serving the powder processing industries will be unveiled on Booth #2443 at Interphex 2012 (1-3 May; New York, USA). This new turnkey isolated milling suite encloses the innovative ARTMiS Automated RealTime Milling System within Powder Systems Ltd's (PSL) containment unit, providing a secure, advanced processing solution for those dealing with highly potent and/or high value materials...

 

  Productivity gains using Mastersizer 3000 add value in raw material testing Mastersizer 3000 from Malvern InstrumentsParticle size analysis of raw materials is often a necessary but routine task where speed and efficiency are critical to decision-making and the smooth operation of a manufacturing process. The Mastersizer 3000 from Malvern Instruments supports improved  productivity through fast, fully automated measurement and cleaning, combined with instrument and data analysis software that streamlines every aspect of the instrument's use. In-built intelligence supports each measurement, from the outset through to a successful conclusion. The result is robust and reliable data produced with ease and efficiency and minimal operator input...

 

  Dow Corning uses Malvern Viscotek GPC to provide customers with in-depth polymer structure data Malvern InstrumentsThe installation of a multi-detection Viscotek TDAmax gel permeation chromatography (GPC) system from Malvern Instruments is enabling Dow Corning Europe S.A. in Belgium to meet customer demand for increasingly comprehensive polymer structure data. In addition, Dow Corning experts are saving resources by applying rapid, cost-effective GPC methods to pre-select the most promising new polymer candidates, significantly reducing the number of nuclear magnetic resonance (NMR) investigations required wherever possible...

 

  Malvern rheology expert contributes chapter to Handbook of Nutraceuticals Malvern InstrumentsDr Samiul Amin, Strategic Technology Group Manager at Malvern Instruments has collaborated with Dr Krassimir P. Velikov from Unilever R&D Vlaardingen to provide a chapter examining the ‘Rheology of Complex Fluids Containing Nutraceuticals', in a recently published book for industry professionals...

 

  New Mastersizer 3000’s intelligent particle sizing supports R&D productivity Mastersizer 3000 from Malvern InstrumentsBy streamlining method development, automating measurement and continuously verifying data quality, the new Mastersizer 3000 laser diffraction particle size analyzer from Malvern Instruments provides R&D scientists with the high degree of flexibility and responsiveness needed to drive efficient, cost-effective product and process development...

 

  Malvern Spraytec excels in zero gravity testing of new fire extinguisher for International Space Station Malvern Spraytec excels in zero gravity testing of new fire extinguisher for International Space StationADA Technologies (Littleton, Colorado, USA) recently confirmed that both NASA's new space-bound fire extinguisher and the Spraytec laser diffraction spray particle size analyzer from Malvern Instruments function in zero gravity just as well as they do on Earth. By carrying out droplet size distribution experiments on the infamous ‘vomit comet', Zero Gravity Corporation aircraft, ADA and NASA researchers have shown that water atomization is independent of gravity and the Fine Water Mist portable fire extinguisher (PFE) currently under development for use on the International Space Station (ISS) will put out fires in space safely and cleanly...

 

  DDL22 poster reports on the power of imaging in OINDP development Malvern InstrumentsImaging specialist Dr Deborah Huck from Malvern Instruments will present a poster at Drug Delivery to the Lungs 22 (7-9 Dec, Edinburgh, Scotland) exploring how automated imaging can be used alongside cascade impaction to support the development of inhaled drug products. Hanne Kinnunen of the Department of Pharmacy and Pharmacology, University of Bath (UK), will also reference work with the Morphologi G3-ID in her presentation ‘Effect of lactose fines on the de-agglomeration behaviour of dry powder inhaler formulations', on Friday 9 December...

 

  Malvern’s light scattering supports formulation development for Novozymes’ recombinant albumins Malvern InstrumentsScientists from Malvern Instruments and from biological ingredients and technology developers, Novozymes Biopharma, have successfully completed the first phase of extensive collaborative studies. These have involved the application of Malvern's light scattering technologies in evaluating the formulation stability of two of Novozymes leading recombinant albumin products - AlbucultÂź and RecombuminÂź - which are used in the manufacture of human therapeutics....

 

  Malvern Instruments scientist receives Ernst Abbe Memorial Award at 50th anniversary of the Eastern Analytical Symposium Malvern InstrumentsDr E. Neil Lewis, Chief Technology Officer at Malvern Instruments can now count the prestigious Ernst Abbe Memorial Award of the New York Microscopical Society among his accolades. He received the award, presented in recognition of his outstanding contributions to the science of microscopy, on 17 November 2011 during the 50th Eastern Analytical Symposium & Exposition in New Jersey, and he joins a list of previous recipients who have made significant contributions to the field. Dr. Lewis is being recognized specifically for the development of chemical imaging microscopy...

 

  University of Texas researchers use Malvern Viscotek systems to characterize challenging polymers Prof. Christopher Bielawski and the Malvern Viscotek system at The University of Texas at AustinThe Viscotek multi-detector gel permeation chromatography (GPC) system from Malvern Instruments is proving to be the ideal solution for researchers at The University of Texas at Austin whose work is taking them to the very limits of what can be achieved by GPC. The research team from the Department of Chemistry and Biochemistry is using multiple Viscotek GPC instruments to help guide the development of new monomers and polymers for use in high performance solar cells...

 

  Driving diffraction’s dry powder dispersion - New Mastersizer 3000 measures the particle size of even friable dry powders Aero S dry powder disperser from Malvern InstrumentsEquipped with the novel Aero dry dispersion unit, the new Mastersizer 3000 particle size analyzer from Malvern Instruments now extends dry measurement to the widest possible range of sample types. The design of the Aero reflects state-of-the-art dry powder dispersion knowledge and enables users to measure materials from cement to coffee, cohesive minerals to fragile pharmaceuticals, from 0.1 micron up to 3.5 mm in the dry state...

 

  Malvern still talking materials after one year! Materials Talks blog celebrates first anniversary Materials Talks blogOn 1 November 2011, Malvern Instruments celebrated the first anniversary of its increasingly successful blog. Launched to open up discussions in the world of materials characterization in a new and exciting way, the Materials Talks blog has gone from strength to strength during 2011 with multiple authors providing science and technology news, views and insight...

 

  HRH The Duke of Kent presents Queen’s Award to Malvern Instruments HRH The Duke of Kent presents the 2011 Queen’s Award for Enterprise to Paul Walker (left), Managing Director of Malvern InstrumentsOn Thursday 27 October 2011, HRH The Duke of Kent visited the global headquarters of Malvern Instruments in Malvern, Worcestershire, UK, to present the company with the 2011 Queen's Award for Enterprise in the category of International Trade. During a tour of the Malvern Instruments' facility the Royal Party was briefed about the company, its history and future plans. They also met staff and saw examples of products and operations...

 

  Malvern specialist presents nasal spray analysis at Indian Pharmaceutical Association Symposium Paul Kippax Malvern InstrumentsDr Paul Kippax, Product Group Manager at Malvern Instruments, will speak at the Indian Pharmaceutical Association's (IPA) 5th Symposium on Nasal and Pulmonary Drug Delivery at Juhu, Mumbai, India 10-11 November 2011. Malvern is a gold sponsor of the event and will also conduct a workshop on using the Spraytec laser diffraction analyzer to characterize pharmaceutical aerosols...

 

  New data demonstrate the value of Zetasizer ”V in protein SEC Zetasizer ”V from MalvernTwo new, free to download, technical notes from Malvern Instruments describe the function and benefits of using the Zetasizer ”V as a detector for size exclusion chromatography (SEC), focusing on its suitability for protein characterization. Capable of dynamic (DLS) and static light scattering (SLS) detection, the compact Zetasizer ÎŒV simultaneously measures absolute size and molecular weight, maximizing the information produced by each measurement to increase experimental productivity. The OmniFACE connection interface from Malvern Instruments (Malvern, UK) enables the...

 

  Award-winning Mastersizer 3000 is tribute to skills of development team The Mastersizer 3000 development teamMalvern Instruments is celebrating the global launch of the next generation of one of its flagship products, already the recipient of an Innovation Award at October’s Powtech event. According to Product Group Manager Paul Kippax, “delivering so many productivity advantages in such a beautiful design is a real tribute to the expertise and skill of the Mastersizer 3000 particle size analyzer product development team at Malvern.” In celebration, development team members have been sharing their experiences on the company’s Materials Talks blog...

 

  Zetasizer Nano used to accurately characterize nanoparticles in ecotoxicology study The Zetasizer Nano from Malvern InstrumentsAssociate Professor James F. Ranville, from the Department of Chemistry and Geochemistry at the Colorado School of Mines, is using a Zetasizer Nano ZS from Malvern Instruments to characterize nanoparticles as part of an ecotoxicology study. Designed to quantitatively detect, characterize and assess the environmental health and safety of metal and metal oxides such as nanosilver, the study aims to uncover what happens when these nanomaterials are released into environments such as our water supply and stomach fluids following ingestion...

 

  New Mastersizer 3000’s high performance particle sizing enables quick, confident decision making from drug development to manufacturing The Mastersizer 3000 from Malvern InstrumentsSpecified to meet the stringent requirements of today's pharmaceutical industry for secure, reliable particle size analysis, the new Mastersizer 3000 laser diffraction system from Malvern Instruments provides a single platform that can be used throughout the drug development cycle, with easy transfer of methods from R&D right through to QC...

 

  Malvern’s Mastersizer 3000 wins Powtech Innovation Award The Malvern Instruments team receives the Innovation Award at Powtech 2011Just a month after its launch, the Mastersizer 3000 laser diffraction particle size analyzer from Malvern Instruments is enjoying yet another moment in the spotlight, as one of the winners at the Powtech Innovation Awards presented on 11 October 2011 at a ceremony in NĂŒrnberg, Germany...

 

  Malvern’s Mastersizer 3000 will be in action at the AAPS Annual Meeting & Exposition Mastersizer 3000 laser diffraction particle size analyzer from Malvern InstrumentsAt this year's AAPS Annual Meeting & Exposition (24-27 October 2011; Washington DC, US), experts from Malvern Instruments will be showcasing the new Mastersizer 3000 laser diffraction particle size analyzer, both on the Malvern booth at the exposition and in a series of live demonstrations. This will be the Mastersizer 3000's first appearance at a US trade show...

 

  Simplifying entangled polymer synthesis. Malvern’s Viscotek 270max helps University of Houston team simplify polymer synthesis Professor Rigoberto Advincula, Department of Chemistry, University of HoustonUniversity of Houston, USA, researchers have recently developed and verified a new route for synthesizing superior forms of entangled or knotted polymers with pre-designed characteristics for use in applications such as drug delivery and smart coatings. Using a Viscotek 270max triple detector gel permeation chromatography (GPC) system from Malvern Instruments, the Houston team successfully confirmed the innovative synthesis of interlocking polymer rings (catenanes) by atom transfer radical polymerization (ATRP) from templated initiators...

 

  Beauty that’s more than skin deep! New Mastersizer 3000 reflects the collective expertise of a skilled development team at Malvern Instruments The development team at Malvern is celebrating the launch of the new Mastersizer 3000 particle size analyzerSince Malvern Instruments revealed the new Mastersizer 3000 laser diffraction particle size analyzer to the world it has become clear that the development team's vision of a beautifully designed, technologically advanced system that anyone can use has been realized. Certainly that's what initial feedback suggests!

 

  New cell makes surface zeta potential measurement quick and easy using standard Zetasizer Nano system A diagram of the new surface zeta potential cell from Malvern InstrumentsA new accessory for Malvern Instruments' Zetasizer Nano particle characterization system allows users to measure the zeta potential of surfaces in an aqueous medium on a standard instrument. Malvern's new surface zeta potential measurement cell eliminates the need to use the specialist technique of streaming potential, which requires instrumentation dedicated only to that measurement...

 

  The new Mastersizer 3000 makes European show debut at Powtech 2011 Mastersizer 3000 laser diffraction particle size analyzer from Malvern InstrumentsAt POWTECH 2011, Not just a new instrument a new Mastersizer. Meet the exciting new Mastersizer 3000 laser diffraction particle size analyzer from Malvern Instruments. Visit the stand or join Malvern’s particle sizing specialists for a detailed presentation and demonstration of the Mastersizer 3000 at the NĂŒrnbergmesse on either 11 & 12 October 2011. Events will run in English and German...

 

  Smaller system, sleeker styling, smarter sizing – meet the new Mastersizer 3000 particle size analyzer from Malvern Instruments Mastersizer 3000 from Malvern InstrumentsRaising particle sizing to a smarter level, the new Mastersizer 3000 from Malvern Instruments delivers unique performance and productivity advantages, wrapped in a stylish, compact and practical instrument design. Now anyone can make good measurements and get exactly the data they need quickly and easily...

 

  Malvern Instruments and Purdue University present joint symposium on light scattering techniques for nanoparticle characterization Malvern InstrumentsMalvern Instruments and the Birck Nanotechnology Center at Purdue University will jointly host a one day symposium on 21st September 2011 examining the application of light scattering techniques in the characterization of nanoparticles. The symposium will take place on the Purdue Campus at West Lafayette, Indiana and is designed for scientists who manufacture, process or formulate nanoparticles, and those working with liposome and biomolecule applications in the area of drug delivery...

 

  University of Iowa’s vocal fold research keeps teachers talking University of Iowa researchers aim to keep our school teachers talking (From left: Alexander Tomesch, Dr. Sarah Klemuk, Andrew Wagner, Stacey Church, John Nichols)Researchers at the Department of Communication Sciences & Disorders at the University of Iowa in the US replicate the stresses that affect the human voice. The team studies how vibration affects laryngeal cells, using a rotational shear rheometer from Malvern Instruments coupled with a piezo-electric driver to measure viscoelastic properties of soft tissues. The team is also part of the National Center for Voice and Speech (NCVS), a consortium of voice researchers and professionals from institutions across the country...

 

  Malvern’s novel diffusion barrier zeta potential method improves protein characterization new diffusion barrier method to eliminate protein denaturation when measuring zeta potential using electrophoretic light scattering. Malvern Instruments has developed a new diffusion barrier method to eliminate protein denaturation when measuring zeta potential using electrophoretic light scattering. Utilising a U-shaped disposable capillary cell, the new method delivers significant improvement in the accuracy and repeatability of zeta potential results for proteins. Ultimately, the method makes protein characterization with Malvern's Zetasizer range even easier. A new application note explaining the technology and its applications is available...

 

  Malvern automates sample filtering for safety and productivity in demanding high temperature GPC applications Viscotek HT-GPCBringing fully automated, state-of-the-art GPC technology to the polyolefin industry, the Viscotek HT-GPC (high temperature gel permeation chromatography) system from Malvern Instruments is detailed in a new brochure available on the company's website. The Viscotek HT-GPC system requires no user interventions for sample filtering and is uniquely specified for safe, routine operation at the high temperatures (160oC) necessary for analyzing polyethylene and polypropylene...

 

  Malvern exhibits new Automated RealTime Milling System at Powtech ARTMiS, a new jointly developed Automated RealTime Milling System. Malvern Instruments will show the very latest in particle characterization systems. Exhibits will include Sturtevant's MicronizerÂź Jet Mill displayed together with a Malvern Insitec particle size analyzer and the Schenck AccuRate Feeder as the first time international introduction of ARTMiS, a new jointly developed Automated RealTime Milling System...

 

  Field experience and new measurement challenges drive enhancements to Malvern’s Insitec L Malvern Insitec L particle size analyzerWorking in conjunction with mineral and metallurgical processing specialists Outotec (Espoo, Finland), and following more than a year's experience in the field, Malvern Instruments has introduced a new version of the Insitec L particle size analyzer. The Insitec L provides a robust solution for real-time measurement of slurries and emulsions...

 

  University of Melbourne student wins Malvern poster prize at UK Colloids 2011 Malvern InstrumentsThe winner of the Malvern Instruments ÂŁ250 prize for the best student poster presented at the recent UK Colloids 2011 conference was Thakshila Balasuriya from The University of Melbourne, for her work describing ‘Dynamic Forces between Bubbles with Switchable Peptide Surfactants'. Thakshila is a third year PhD student in the Dynamic Interfacial Forces Group...

 

  New software for Malvern’s Morphologi G3 puts particles in a different light! Particle image from the Morphologi G3 using episcopic dark-field with colour and polarizers  Malvern Instruments has released a new version of software for the company's Morphologi G3 particle characterization system. This fully automated image analysis-based system delivers particle size and shape information for wet and dry samples, and for the analysis of foreign particulate matter collected on filters. Among the new applications in the version 7.40 software are facilities for user-defined light settings and automated dark-field measurements...

 

  Malvern’s Viscotek TDAmax “warms the heart” of an academic polymer scientist Professor Kenneth J Wynne "Good value and excellent performance is a combination that will warm the heart of any academic polymer scientist," said Professor Kenneth J Wynne of the Department of Chemical and Life Science Engineering at Virginia Commonwealth University, when asked about his 11-year use of Viscotek gel permeation chromatography (GPC) systems from Malvern Instruments...

 

  Malvern Instruments and Paraytec enter into development and technology licensing agreement Malvern InstrumentsMalvern Instruments Ltd (Malvern, UK) and Paraytec Ltd (York, UK) have entered into a development and licensing agreement that will see Paraytec's ActiPixÂź technology being added to Malvern's materials characterization portfolio. The agreement will give Malvern exclusive rights to further develop, market and sell ActiPixÂź UV area imaging technology in specific fields of use related to the characterization of complex fluids for applications in biopharmaceuticals, foods and personal care industrial sectors...

 

  Malvern particle characterization supports cost control in solar cell manufacture The Sysmex FPIA-3000 from Malvern InstrumentsWorldwide demand for photovoltaic (PV) solar cells is fuelling the emergence of a strong manufacturing sector across Europe and Asia. In support, the Sysmex FPIA-3000 Flow Particle Image Analyzer from Malvern Instruments is being used to aid cost control and waste reduction by providing the particle size and shape data necessary for effective recycling of the high value slurries used in cutting silicon wafers...

 

  University of Sheffield choose Zetasizer Nano from Malvern Instruments to monitor the rapid and efficient production of nanolatexes Transmission Electron Microscopy image of nanolatex particles prepared by aqueous dispersion polymerisation. Image courtesy of Prof. Steve Armes of Sheffield University,Prof Steven Armes and his research team in the Department of Chemistry, at The University of Sheffield in the UK, are using a Zetasizer Nano from Malvern Instruments to monitor the rapid and efficient production of nanolatexes. This single instrument can determine both the particle size distribution and also monitor the zeta potential, making it an ideal characterisation tool for following the in situ synthesis of many types of polymer colloids, such as latexes, microgels or colloidal nanocomposite particles...

 

  Malvern Instruments sponsors UK Colloids 2011 Malvern InstrumentsMalvern Instruments is a major sponsor for UK Colloids 2011, a new international colloid and surface science symposium that takes place in London, UK, from 4-6 July. The event, jointly organized by the Royal Society of Chemistry (RSC) Colloid and Interface Science Group and the Society of Chemical Industry (SCI) Colloid and Surface Science Group, is an opportunity for researchers to discuss current issues in the field. Scientists from Malvern will take an active role in the conference itself and part of Malvern's support for the meeting includes sponsorship of the poster prize...

 

  Malvern Zetasizer Nano shows aptitude for interdisciplinary research at Purdue Malvern InstrumentsResearchers at the Birck Nanotechnology Center (BNC) within Purdue University's unique Discovery Park, are finding the Malvern Instruments Zetasizer Nano particle characterization system is ideally suited to the center's interdisciplinary research environment. The system is housed within the Chemical Nanotechnology/Microfluidics laboratory and users range from those who are highly experienced with the instrument to complete novices...

 

  University of Georgia materials researchers rely on Malvern’s Viscotek GPC the Viscotek TDAmax system "The Viscotek gel permeation chromatography system with triple detection is the most important tool in our laboratory," said Assistant Professor Jason Locklin of the Department of Chemistry and Faculty of Engineering, University of Georgia, when referring to the Viscotek TDAmax system from Malvern Instruments...

 

  Dry powder nasal sprays a hot topic at RDD Malvern InstrumentsLaser diffraction particle size analysis, already widely used in the characterization of a variety of OINDPs (orally inhaled and nasal drug products) is proving its value in the development of some of the newest drug delivery formulations - dry powder nasal sprays. This was the conclusion of a well-attended workshop on ‘Characterizing the Performance of Nasal Dry Powder Devices' presented by Dr Paul Kippax, from Malvern Instruments, and Dr Julie Suman, President of NextBreath LLC, during May's Respiratory Drug Delivery Europe 2011 (RDD 2011) conference in Berlin, Germany...

 

  Malvern particle characterization systems help Sweden’s YKI connect colloid science with product formulation Malvern Zetasizer NanoSweden's YKI, Institute for Surface Chemistry, a subsidiary of the SP Technical Research Institute of Sweden, is combining the benefits of the Mastersizer 2000 and Zetasizer Nano particle characterization systems from Malvern Instruments, in order to aid their customers in developing stable products with improved physical properties...

 

  New video and conference poster highlight versatility of Parsum In-line Particle Probe The Parsum In-line Particle Probe A new 3-minute video highlighting the versatility of the Parsum IPP 70 In-line Particle Probe is now available on the Malvern Instruments website. Designed to measure continuously the size, size distribution, and velocity of granular particles, directly in the process, the Parsum In-line Particle Probe (IPP) is a valuable tool for process development and automated production. It has applications in many sectors including the food, chemical and pharmaceutical industries...

 

  Malvern Instruments host a series of complimentary training schools for users of the Viscotek triple detection gel permeation/size exclusion chromatography (GPC/SEC) systems. Part of the Viscotek range of GPC/SEC systems, the Viscotek TDAmax comes with a triple or tetra detector array suitable for all macromolecular applications.Malvern Instruments will host a series of complimentary training schools in North America this year for users of the company's Viscotek triple detection gel permeation/size exclusion chromatography (GPC/SEC) systems...

 

  Malvern’s new telephoto lens challenges the limits of real-time particle size measurement Malvern InstrumentsThe introduction of a new telephoto lens for Insitec laser diffraction process systems from Malvern Instruments enables the on-line measurement of larger particles, extending their application in the minerals, powder coatings and food industries, amongst others...

 

  Malvern Instruments to lead workshop on ‘Characterization techniques for protein therapeutics’ Malvern ZetasizerDrs Kevin Mattison*, Ulf Nobbmann and Jason Sanchez of Malvern Instruments will lead a workshop on ‘Characterization techniques for protein therapeutics' - at the 7th Annual PEGS - Protein & Antibody Engineering Summit being held in Boston MA, from 9-13 May 2011...

 

  Exploring the links between rheology, gel permeation chromatography and particle characterization The Kinexus rotational rheometerAt the 7th Annual European Rheology Conference (AERC 2011), May 10 - 14, 2011, Suzdal, Russia, Malvern Instruments will focus on how to maximize analytical benefit and impact by combining rheology with complementary techniques such as gel permeation chromatography and particle characterization...

 

  Industrial corrosion protection systems manufacturer uses Malvern Kinexus rheometer in formulation development The Kinexus rotational rheometer from Malvern InstrumentsDevelopment teams at Steuler KCH Materials GmbH (Siershahn, Germany) are using the Kinexus rotational rheometer from Malvern Instruments to help analyze the rheological characteristics of products such as spray coatings. Steuler KCH GmbH is a world leader in the provision of industrial corrosion protection, in the form of mechanically and thermally resistant materials and linings for steel and concrete structures...

 

  Tools for Polymer Characterization The Viscotek TDAmax GPC system from Malvern InstrumentsMaterials characterization company Malvern Instruments is focusing on tools for polymer characterization as part of its exhibit at this year's Annual Technical Conference for the polymer industry (ANTEC 2011, May 1-5, Boston MA, USA). Highlights include Malvern's Viscotek gel permeation chromatography (GPC) systems for measuring polymer architecture and the company's range of capillary rheometers for determining polymer processability...

 

  ‘Two in a row’ as Malvern Instruments wins Queen’s Award Exchanging gifts: Paul Walker (right) Managing Director of Malvern Instruments and Hisashi Ietsugu, President and CEO of Sysmex Corporation during a recent celebration to mark the extension of Malvern’s direct operations in JapanUK-based materials characterization company Malvern Instruments is celebrating winning the Queen's Award for Enterprise in two successive years. Details of the 2011 awards were announced on 21st April, with Malvern receiving the Queen's Award for Enterprise in the category of International Trade. While this is a considerable achievement in its own right, it is all the more noteworthy for being the seventh time that Malvern Instruments has been recognised in the Queen's Awards...

 

  Poster and podium presentations for Malvern team at Polymer Processing Society Annual Meeting 2011 The Kinexus Rotational Rheometer enables users to analyze precisely the rheology, flow and deformation properties of different samples.Dr Gerhard Heinzmann from Malvern Instruments will make poster and podium presentations at the 27th Annual Meeting of the Polymer Processing Society, which takes place in Marrakech, Morocco from 10-14 May 2011. The subject of the poster is Large Amplitude Oscillatory Shear (LAOS) measurement of polymer gels, while the podium presentation will discuss the use of gel permeation chromatography (GPC) to study poly methyl methacrylate (PMMA)...

 

  Join discussions about zeta potential measurement at the International BES Symposium 2011 The Zetasizer Nano measures particle size, zeta potential and molecular weight of colloids, nanoparticles and proteinsMalcolm Connah, Product Marketing Manager, Nanometrics for Malvern Instruments, will make presentations about novel methods for measuring the zeta potential of proteins at a pre-conference workshop and as part of the plenary session during the 21st International Symposium of the Bioelectrochemical Society (BES). The conference takes place in Cracow (Poland) from 8-12 May 2011...

 

  Made to measure viral drug delivery. Malvern’s Zetasizer Nano proves to be the perfect instrument for a student environment The Zetasizer Nano in use at Indiana University’s (IU) Molecular and Cellular Biochemistry departmentWhile viruses are so often seen as the enemy, modern scientific techniques may soon be able to harness the strengths of a virus for drug delivery systems that are designed to treat diseases, rather than cause them. Using a Zetasizer Nano particle characterization system from Malvern Instruments, researchers at Indiana University's (IU) Molecular and Cellular Biochemistry Department have been studying self-assembled virus-based drug delivery systems that can be tuned to a particular size enabling the uptake of specific functional cargo...

 

  Malvern specialist discusses light scattering techniques at BioProcess International Europe 2011 Malvern InstrumentsMalvern Instruments' product technical specialist, Dr Hanna Jankevics, will present a poster on ‘Light scattering for protein characterization in formulation studies' at the 7th annual BioProcess International Europe conference in Nice (France), which runs from 6 - 7 April 2011. The conference includes sessions to discuss protein aggregation, cell culture, and formulation in biomanufacturing...

 

  Malvern’s upcoming webinars for process engineers Malvern Insitec particle size analyzerA series of webinars aimed at those working in the processing environment will take place during April, May and September 2011 as part of Malvern Instruments' extensive web seminar program. Subjects covered will range from the use of on-line particle sizing in micronization through to process optimization and control of cement production. Two further webinars will be available in Portuguese. These events are free to attend, and open to all...

 

  Malvern Instruments Insitec system is integral to new Automated RealTime Milling System on Sturtevant Inc. booth #1827 at Interphex 2011 Malvern Instruments Insitec on-line particle size analyzerFollowing recent joint development, Malvern Instruments Insitec on-line particle size analyzer will be exhibited on the Sturtevant Inc. booth at Interphex 2011 (March 29-31, New York). The Insitec will be displayed together with a Sturtevant Mill and Schenck Accurate Feeder as the first time introduction of ARTMiS, a new Automated RealTime Milling System.

 

  Morphologi G3 with Raman microprobe helps identify particulate contaminants Raman spectra using the Morphologi G3-IDA new application note describing ‘Raman chemical identification of contaminant particles’ is now available on the Malvern Instruments website. It highlights the ability of the company’s Morphologi G3 equipped with Raman microprobe accessory to target particulate impurities, an area of considerable interest to manufacturers of complex, high value products where control of particle size and shape is crucial...

 

  Malvern Instruments joins SoftComp Consortium and European Soft Matter Infrastructure (ESMI) Project Malvern InstrumentsMaterials characterization specialist Malvern Instruments has joined two key European initiatives that aim to promote excellence in cross-disciplinary research and technique development in soft matter composites and complex fluids. These are: the SoftComp Consortium; and, the newly funded EU FP7 project, European SoftMatter Infrastructure (ESMI)...

 

  Malvern specialist will focus on particle size and shape analysis at workshop on building materials analysis Malvern InstrumentsRolf Weiser, Sales Manager for Germany at Malvern Instruments, is part of a line up of invited speakers at ‘Building materials analysis 2011', a workshop organised by the Mineralogical/Geochemical Group of the University of Halle/Saale in Germany in co-operation with Malvern's sister company PANalytical...

 

  New publication describes laser diffraction and automated imaging for characterizing nasal sprays Malvern Instruments’ Spraytec and Morphologi G3-ID use powerful, complementary techniques to enable the efficient characterization and commercialization of nasal spray products.A newly published article demonstrates the effectiveness of combining laser diffraction and automated particle imaging (including Raman spectroscopy) in the characterization of nasal spray products. Co-authored by materials characterization specialists from Malvern Instruments together with Julie Suman, President of Nextbreath LLC, ‘Characterizing a nasal spray formulation from droplet to API particle size' can be downloaded from the Malvern website...

 

  Lund University scientists rely on the Zetasizer Nano ZS for cost-effective molecular characterization The Malvern Zetasizer NanoThe work of Dr Sindra Peterson Årsköld, Associate Professor, and her colleagues at Lund University’s (Sweden) proton channel group, focuses on liposomal investigations of viral proteins and anti-viral agents. The liposomes are used as artificial models of the virion, enabling systematic scrutiny of key membrane-bound drug targets. Dr Peterson Årsköld believes that, because her research depends on accurate, routine sample quality control in a wide range of sample conditions, it would not be feasible without the rapid, reliable, resource-efficient measurement capabilities of the Zetasizer Nano particle characterization system from Malvern Instruments...

 

  Engineering nanoparticle coatings -Quebec researchers use Malvern’s new high temperature chromatography system in novel work Drops of water at the surface of a novel polyolefin coating on a steel coupon, showing the low wettability of the coatingResearchers working at NanoQAM, the nanotechnology research centre of the University of Quebec (Montreal, Canada), are successfully innovating novel polymer coatings on the basis of data measured using a Viscotek high temperature gel permeation chromatography (HT-GPC) system from Malvern Instruments. The system is proving crucial for efficient polymer characterization, reliably providing absolute molecular weight and structural information to support research goals...

 

  Malvern specialist explores real-time particle size analysis at Europact The Insitec online particle size analyzer Bernd Looser, Applications Specialist for Process Systems at Malvern Instruments, will discuss particle size analysis both as part of a pre-conference course and in a poster session at EuroPACT 2011, the 2nd conference on process analytics and control technology being held in Glasgow from April 26th - 29th. Malvern Instruments will also exhibit at the associated trade show...

 

  Using GPC/SEC to accurately characterise complex biopolymers in food Published work, now freely available on the Malvern Instruments website, shows that the Viscotek TDAmax gel permeation/size exclusion chromatography (GPC/SEC) system is an information-rich, time-efficient analytical solution for the comprehensive characterization of complex food ingredients and additives based on polysaccharides. The work by Dr Gerhard Heinzmann and Dr Bernd Tartsch is detailed in a paper "Alginates, Chitosanes and Xanthans - Characterisation of Food Ingredients by GPC/SEC with Triple Detection".

 

  Method development for laser diffraction particle size analysis Malvern InstrumentsRecently published and now available for download on the Malvern Instruments website, ‘Method development for laser diffraction particle size analysis' by diffraction specialist Dr Anne Virden provides practical guidance on developing robust analytical methods.

 

  Malvern’s new SEC-LS dual integrated detector is dedicated to proteins Zetasizer ”V with OmniFACE and OmniSECMalvern Instruments has launched the Zetasizer ”V with OmniFACE and OmniSEC, a new SEC-LS (size exclusion chromatography - light scattering) detector package dedicated to protein analysis. The proven Zetasizer ”V offers dual DLS (dynamic light scattering) and SLS (static light scattering) capabilities. It can be used as a stand-alone detector, analyzing samples in a cuvette, and now as a fully-featured modular chromatography detector. For protein applications, this makes the Zetasizer ”V an ideal tool

 

  Easing the transition into profitable manufacture Malvern Instruments INFORM white paperMalvern Instruments latest INFORM white paper - ‘The benefits of real-time analysis for process development' - presents the case for investing in real-time process measurement at the pilot studies stage, and is now available for free download from the company's website

 

  And the winner is
‘Basic Principles of Particle Size Analysis’ – Malvern’s most downloaded document Malvern Instruments Ltd Materials characterization company Malvern Instruments is known for the breadth and accessibility of the educational offering on its website, from simple news stories to in depth applications notes and interactive presentations. However, by far the most popular document is ‘Basic Principles of Particle Size Analysis', a paper written by Applications Manager Dr Alan Rawle, that has been downloaded more than 7500 times in the past three years.

 

  Malvern Kinexus installed in new GMP testing facility at NMI Reutlingen Malvern KinexusResearchers at the Natural and Medical Sciences Institute (NMI) at the University of TĂŒbingen in Germany have installed a Kinexus rheometer from Malvern Instruments in the new GMP testing facility at its subsidiary, NMI Technologietransfer GmbH. The Kinexus is used primarily for the characterization of biomaterials, mainly hydrogels containing patient cells..

 

  Malvern shows new SEC-LS dual integrated detector package at macromolecules conference Zetasizer ”V with OmniFACE and OmniSECMalvern Instruments will introduce the Zetasizer ”V with OmniFACE and OmniSEC, a new SEC-LS (size exclusion chromatography - light scattering) detector package, at SCM-5, the 5th International Symposium on the Separation and Characterization of Natural and Synthetic Macromolecules

 

  Zetasizer Nano supports functional nanoparticle development at micromod Partikeltechnologie GmbH Zetasizer NanoResearchers at micromod Partikeltechnologie GmbH are using the Zetasizer Nano particle characterization system from Malvern Instruments, equipped with an MPT-2 Autotitrator and degasser, to determine particle size and to measure the zeta potential of nanoparticles as a function of pH.

 

  Particle and molecular characterization focus for Malvern Instruments short courses at Pittcon 2011 Malvern InstrumentsMalvern Instruments will run two one-day short courses as part of the established program at Pittcon 2011(March 13th -18th 2011; Atlanta GA). The first of these on March 14th covers the fundamentals of particle sizing with an emphasis on light scattering techniques, and the second, which takes place March 16th, examines molecular and particle characterization by dynamic light scattering and zeta potential. Registration is open for both via the Pittcon website.

 

  Malvern’s Mastersizer 2000 is frontline instrument for research into the health hazard of volcanic ash Malvern’s Mastersizer 2000 is frontline instrument for research into the health hazard of volcanic ashThe Mastersizer 2000 laser diffraction particle size analyzer is one of the first instruments applied by scientists when assessing the respiratory health hazard of volcanic ash. Dr Claire Horwell, Director of the International Volcanic Health Hazard Network, receives volcanic ash samples from all over the world at her lab at Durham University, UK. Working within the Institute of Hazard Risk and Resilience, Dr Horwell's remit is to provide rapid advice as to the likely health hazard of ash from particular volcanoes to support agencies working at the site of the eruption.

 

  Malvern Instruments experts win industry poster award at DDL21 Malvern team receives DDL Industry Poster Award (from left: Carl Levoguer, Andrew France, Deborah Huck, Anne Virden).This year's Drug Delivery to the Lungs conference (DDL21; 8-10 Dec 10; Edinburgh, Scotland), was a resounding success for Malvern Instruments with Deborah Huck, Malvern's Product Technical Specialist for imaging, and co-authors scooping the industry poster award for, "Characterizing a Nasal Spray Formulation from Droplet to API Particle Size." The prize was presented to the team by Jolyon Mitchell of Trudell Medical International and highlights Malvern's active development of analytical instrumentation for inhaled product applications

 

  Malvern Link II named as Breakthrough Product of the Year Malvern Link IIMalvern Link II has been named by Processing magazine as one of its Breakthrough Products of the Year for 2010. This powerful OPC-standardized software package from Malvern Instruments provides a universal interface for system integrators, simplifying the integration of analytical devices with expert control systems in manufacturing processes.

 

  ‘Blogs away’ for Malvern Instruments at www.materials-talks.com Malvern InstrumentsWith the launch of www.materials-talks.com the Malvern Instruments team have opened a new global channel through which they can share their thoughts, opinions, experience and expertise, and readers are most definitely encouraged to share back!

 

  Malvern to present US asphalt market survey at 12th annual AMAP Conference Rheology specialists from Malvern Instruments will present the very latest statistics about modified asphalt use in the United States at the 12th annual conference of AMAP - the Association of Modified Asphalt Producers. The conference takes place in Kansas City, MO, from 15 - 17 February 2011. Details of the survey will be presented as part of the main conference program by John Casola, Products Sales Manager at Malvern Instruments, who will also be one of the instructors at an opening day workshop covering "An introduction to modified asphalt binder and emulsion technology ".

 

  Explaining molecular sizing using GPC/SEC molecular sizing using GPC/SEC For many applications that include the use of biologically important molecules, such as proteins or polysaccharides, molecular size is an important parameter but its accurate measurement can be challenging. A new application note from Malvern Instruments describes the use of triple detection gel permeation/ size exclusion chromatography (GPC/SEC) using the VIscotek TDAmax system for this purpose.

 

  Malvern discusses complementary techniques for OINDP analysis at DDL 21 Morphologi (left) and Spraytec systems from Malvern InstrumentsAs well as exhibiting at this year's Drug Delivery to the Lungs conference (DDL21; 8-10 Dec 10; Edinburgh, Scotland), specialists from Malvern Instruments will present a scientific poster "Characterizing a nasal spray formulation from droplet to API particle size", which examines the complementarity of automated image analysis and laser diffraction for characterizing nasal spray formulations

 

  Malvern shows latest imaging solutions at AAPS Malvern InstrumentsVisitors to Malvern Instruments booth (#1647) at next week's AAPS Annual Meeting and Exposition will have an early opportunity to discover the benefits of integrating the automated size/shape analysis of particles with the chemical identification provided by Raman spectroscopy, using Malvern's Morphologi G3-ID system.

 

  Malvern specialist to speak at London seminar on challenges and experiences of developing dry powder inhalers Malvern Instruments logoOn November 8 2010, Dr Paul Kippax, product group manager for Micrometrics systems at Malvern Instruments, will speak about the use of laser-based technologies in formulation screening, as part of a seminar focusing on the experiences and challenges of developing dry powder inhalers. The one-day seminar precedes the annual Management Forum conference on Inhaled Drug delivery, an international event that takes place on the 8 and 9 November at Le Meridien Hotel, Piccadilly, London, UK

 

  Macromolecular separations made simple! Macromolecular separations Delve into the background and theory behind one of today's most powerful techniques for separating and characterizing natural and synthetic polymers. The theory behind all aspects of Gel Permeation Chromatography (GPC), also known as Size Exclusion Chromatography (SEC), is clearly and simply set out in a series of pages on the Malvern Instruments website

 

  Building Teeth. Dental researchers use Malvern Zetasizer Nano to characterize tooth enamel made in the laboratory Dental researchers use Malvern Zetasizer Nano to characterize tooth enamel made in the laboratoryDr Vuk Uskokovic, from the Department of Preventive and Restorative Dental Sciences, School of Dentistry at the University of California, San Francisco (UCSF), is involved in a study that aims to mimic the growth of tooth enamel in the laboratory. A key analytical tool in this NIH-funded project is the Zetasizer Nano particle characterization system from Malvern Instruments.

 

  Malvern rheologists play a lead role in NCAT project to develop new test standards for asphalt Malvern rheologists play a lead role in NCAT project to develop new test standards for asphalt"Growth in the use of polymer modified binders has intensified the need for more appropriate testing, prompting the National Cooperative Highway Research Programme (NCHRP) to initiate this project," remarks Dr. Randy West, director of NCAT. "Malvern's support for the work has been exemplary throughout, most especially in the development of a new oscillatory test method which was very much a product of their expertise.

 

  Malvern specialist tests sensitivity limits of dynamic light scattering A recording of a recent Malvern Instruments web seminar addressing the question of "What is the real sensitivity of DLS [dynamic light scattering] for nanoparticle and protein measurements?" is now freely available on line. In the seminar, biophysical characterization specialist Dr Ulf Nobbmann explores the limits of each system in the Malvern Zetasizer Nano range and examines best practice methodologies for measuring nanoparticle and protein samples at the extreme ends of the particle size scale

 

  Real-time emulsion monitoring for the oil industry - Malvern presents new research at ChemInnovation 2010 Close up of the Malvern LPS online particle size analyzerDuring ChemInnovation 2010, (19 - 21 Oct 2010, Houston, Texas) Jeff DeNigris, Sales Manager, Process Systems from Malvern Instruments will present new collaborative work with the Universidade Federal de Itajuba, Brazil (UNIFEI) demonstrating the value of Insitec, an on-line particle size analyzer, for monitoring the droplet size of oil/water emulsions.

 

  Zetasizer Nano proves indispensable for studying nanoparticles in water Researchers in the new environmental nanoscience laboratory at Baylor University's Department of Geology (Texas, USA) hail the Zetasizer Nano from Malvern Instruments as an indispensable laboratory instrument. Run by Dr. Boris Lau, the new laboratory addresses cutting edge research focusing on the fate and transport of nanomaterials in an aquatic environment.

 

  Malvern rheometer helps Grace Davison bring new food-grade sealants to market Rotational Rheometer from Malvern Instruments Grace Davison Materials and Packaging Technologies, a product group of W. R. Grace and Co, a leading supplier of state-of-the-art closure systems for rigid packaging, uses a rotational rheometer from Malvern Instruments to accelerate the development of new food-grade and industrial sealants.

 

  Malvern imaging specialist to review NIRCI applications for pharma at FACSS 2010 Analytical imaging specialist Dr Janie Dubois of Malvern Instruments will present a paper reviewing the role of near infrared chemical imaging (NIRCI) in the pharmaceutical industry at the Federation of Analytical Chemistry and Spectroscopy Societies FACSS 2010 conference. The conference takes place from October 17th - 21st in Raleigh, North Carolina.

 

  Malvern specialist presents at PEGS Europe protein aggregation short course Dr Berndt Tartsch, protein applications specialist for size exclusion chromatography and light scattering techniques at Malvern Instruments, is one of three speakers presenting a pre-conference short course on "Protein Aggregation in Biopharmaceutical Products" on 4 October 2010 as part of the 2nd PEGS Europe - Protein & Antibody Engineering Summit. PEGS Europe this year runs alongside Biotechnica in Hannover, Germany

 

  From marine sediments to storm drains – multiple applications for Trinity College Dublin’s Mastersizer 2000 Thanks to its versatility, the Mastersizer 2000 particle size analyzer (Malvern Instruments) installed in the School of Natural Sciences at Trinity College Dublin (Ireland) is proving to be an essential tool for a number of different research groups whose projects range from particle sizing in marine sediments to the investigation of storm drains - and even analyzing dust from the university library.

 

  ‘Why closer is better’ - new GPC/SEC application note from Malvern Instruments A newly available application note from Malvern Instruments explains why, when measuring samples using Gel Permeation Chromatography/Size Exclusion Chromatography (GPC/SEC), low angle light scattering (LALS) is the only LS technique that actually measures a scattered light intensity directly proportional to molecular weight.

 

  Lord Lieutenant presents 2010 Queen’s Award to Malvern Instruments Sir Michael Brinton, the Lord Lieutenant* of Worcestershire, today formally presented the 2010 Queen's Award for Enterprise in Innovation to materials characterization company Malvern Instruments in a ceremony held at its UK headquarters and attended by employees from all parts of the organisation.

 

  Analyzing Dynamic Light Scattering. New Malvern Instruments presentation examines factors for success "What is the real accuracy and reproducibility of dynamic light scattering and the relevance for my applications?" is the question tackled by Biophysical Characterization Specialist Dr Ulf Nobbmann in a new downloadable presentation available via the Malvern Instruments website.

 

  Additional speakers add new dimensions to Particle Summit program Organisers of the two-day Particle Summit, which takes place near Boston in October (October 20-21, 2010; The Charles Hotel, Cambridge MA), have announced two further speakers for the event, adding to an already packed program

 

  Malvern Spraytec helps specialist manufacturer optimize furniture coating Researchers from Becker Acroma, a manufacturer of high quality solutions and customised systems for the wood finishing industry, have used the Spraytec laser diffraction particle size analyzer from Malvern Instruments to help optimize the application of water-based furniture coatings using airless spraying.

 

  Big jump in demand for Malvern’s real-time process control consultancy Since introducing a consultancy service in 2007 that enables clients to examine the implications of implementing real-time process control, Malvern Instruments has seen uptake grow each year. By July, demand in 2010 was already more than double that for the whole of 2009.

 

  Minerals, metals and the Malvern Morphologi! Particle characterization by image analysis using the Morphologi G3 from Malvern Instruments is proving valuable in a diverse range of mineral and metals applications. The shape and size of mineral and metal particles can play an important role in determining process efficiency and final product quality in applications spanning the measurement of metal powders for Metal Injection Moulding (MIM) to the production of mineral-based cosmetics

 

  New Malvern presentation tackles the “overlooked second virial coefficient” Dr Jean-Luc Brousseau from the separations systems team at Malvern Instruments has recorded a downloadable presentation that helps illustrate the importance of specific analytical details when characterizing protein or polymer solutions. In "On the overlooked second virial coefficient" he explains the reasons why and how protein and polymer scientists can improve characterization results by measuring the 2nd virial coefficient, using either static light scattering or gel permeation chromatography/size exclusion chromatography (GPC/SEC).

 

  Malvern Instruments extends direct operations in Japan Malvern Instruments is extending its direct operations in Japan and has concluded an agreement with Sysmex Corporation, the current distributor of its laboratory-based particle characterization systems, to transfer responsibility for sales and support to Malvern Instruments Japan.

 

  Malvern exhibits new applications for Viscotek TDAmax At the American Chemical Society (ACS) Fall 2010 National Meeting & Exposition (August 22-26, Boston, MA), Malvern Instruments will exhibit the Viscotek TDAmax multiple detection gel permeation chromatography (GPC) system together with instruments from the Zetasizer particle characterization family.

 

  Light scattering and chromatography – Malvern exhibits characterization solutions at Protein Society Conference Malvern Instruments is exhibiting the latest in its comprehensive range of solutions for characterizing proteins, peptides and other macromolecules at the 24th Annual Symposium of The Protein Society, August 1-5, 2010 at the Manchester Grand Hyatt San Diego in San Diego, California.

 

  ‘Still spraying after all these years
?’ Malvern offers prize draw at ILASS Europe for photos of active 2600 systems It is now 30 years since the launch of the 2600, Malvern Instruments' first laser diffraction particle size analyzer capable of routine, rapid spray droplet size measurements. To celebrate, Malvern wants to contact anyone still successfully using the 2600 for spray analysis and is inviting visitors to ILASS Europe (6 - 8 September 2010, Brno, Czech Republic) to bring a photo of their 2600 in action to the Malvern booth. Anyone who does so will be entered into a prize draw to win an iPod Nano. Alternatively photos can be posted to 2600@malvern.com

 

  Reverse engineering tablets for counterfeit investigations Chemical imaging specialists at Malvern Instruments are demonstrating how data derived from reverse engineering of pharmaceutical tablets can aid the fight against counterfeit drugs. Using the SyNIRgi near infrared chemical imaging (NIRCI) system they have been able to collect data detailed enough to characterize the formulation and processes used to create individual dosages

 

  Registration opens for inaugural Particle Summit Information-rich, practical program focusing on particle and molecular characterization

 

  Particle shape analysis throws new light on battery performance Work undertaken in Japan and described in a new application note on the Malvern Instruments website, examines the influence of particle shape on the characteristics of coating film for battery electrodes. Using the Sysmex Flow Particle Image Analyzer FPIA-3000, available from Malvern Instruments, researchers at Hokkaido University looked at both the size and shape of graphite particles in coating films produced by different methods

 

  Malvern’s Zetasizer Nano supports charge optimization in water treatment plants An advanced particle characterization system from Malvern Instruments is being used to support water treatment plant operators in their optimization of treatment processes, and is removing the need to wait for external laboratory results. Saving valuable resources, the Zetasizer Nano enables operators to easily measure and track the zeta potential (charge) of inflowing waters on site - hourly, daily, or across cycles, according to seasonal needs.

 

  Fleming PTC and Malvern Instruments unique approach accelerates co-extrusion process development Recent polymer co-extrusion studies demonstrate the value of a unique die developed by Fleming Polymer Testing and Consultancy, for use with the Rosand capillary rheometer from Malvern Instruments. In combination the die and rheometer generate all the data needed to develop and validate co-extrusion process models, reducing the need for pilot scale studies.

 

  New Malvern web resource goes straight to the point for OINDP With the continuing focus on OINDPs (orally inhaled and nasal drug products) as effective delivery vehicles for a wide variety of therapeutics, Malvern Instruments has established a new gateway within its website that guides visitors directly to technical information, downloadable application notes, case studies and interactive presentations on particle size measurement for this class of product

 

  Leading academics select Viscotek GPC systems for polymer reaction engineering research A team of researchers led by Professor Timothy McKenna, Canada Research Chair in polymer reaction engineering at Queen's University in Kingston, Ontario, is using the Viscotek TDAmax gel permeation chromatography (GPC) system from Malvern Instruments to optimize polymerisation conditions for the production of specifically tailored materials, including those with applications in the paints and adhesives industries.

 

  Malvern publishes online chemical imaging bibliography By combining conventional spectroscopy with sophisticated mapping and imaging technology in its SyNIRgi chemical imaging system and ISys chemical imaging software, Malvern Instruments has greatly extended the application of vibrational spectroscopy. This is evidenced by the extensive online chemical imaging bibliography now available on Malvern's website. Research papers and published abstracts by both Malvern users and Malvern's own experts demonstrate a vast range of practical case studies using SyNIRgy, ISys or both.

 

  Malvern exhibits at NanoMaterials 2010 as conference aims at ‘inspiring commercial success’ Malvern Instruments is exhibiting the Zetasizer Nano particle characterization system at NanoMaterials 2010, on 8-10 June at the Hotel Russell in London, UK. Europe's leading conference and exhibition on the safe and profitable commercialisation of nanomaterials, the theme of this year's NanoMaterials is ‘Inspiring commercial success'.

 

  Powering up! Malvern Mastersizer 2000 helps manufacturers improve battery design As battery developers and manufacturers strive to combine even greater power storage and output into lightweight, fast-charging products, the Mastersizer 2000 laser diffraction particle size analyzer from Malvern Instruments is proving valuable in characterizing the materials used to make electrodes.

 

  Protein analysis under spotlight in Malvern’s free webinar On Tuesday, 8 June 2010, at 10:30 am EDT - Eastern Daylight Time/ 3.30pm BST - British Summer Time, Malvern Instruments will deliver a web seminar focusing on light scattering and chromatography, key laboratory tools for protein formulation and characterization studies.

 

  SDTech/Malvern Instruments collaboration enters a new phase Following a number of convincing trials over the past year, SDTech, a company specialising in the micronisation and analysis of powders, has opted to routinely use a dedicated Insitec Voyager system for on-line particle size analysis.

 

  Malvern ISys 5.0 cross-platform chemical imaging analysis software available to license Rapidly becoming the industry standard for analyzing chemical imaging data, ISys 5.0 from Malvern Instruments is available for license on a wide range of analytical systems.

 

  High sensitivity of Zetasizer Nano proves essential for protein aggregation studies at University of South Florida Dr Martin Muschol, Assistant Professor at the University of South Florida's (USF) Department of Physics and his team are carrying out important research to gain a better understanding of protein aggregation phenomena, including protein crystallization and amyloid fibril growth.

 

  Malvern’s ‘can do’ attitude wins repeat asphalt rheology business with Holly Holly Asphalt's purchase of five Dynamic Shear Rheometers over a period of eight years is testament to Malvern's ability to provide exemplary support to asphalt producers, and to sustain and nourish long-term commercial relationships.

 

  Sysmex FPIA-3000 measures sub-visible particulates in biotherapeutics Specialists at Malvern Instruments have demonstrated the application of dynamic particle image analysis to the measurement of sub-visible particulates in biological therapeutics, using the Sysmex FPIA-3000 particle characterization system.

 

  Malvern Instruments celebrates fifth Queen’s Award Now entering its fortieth year in business, materials characterization specialist Malvern Instruments is celebrating winning its fifth Queen's Award, a significant achievement that reflects the drive and commitment of everyone in this high-tech company.

 

  Light scattering illuminated – New eLearning courses from Malvern Instruments Malvern Instruments has introduced a comprehensive eLearning course that details light scattering for materials characterization using the company's Zetasizer Nano system. Course modules introduce dynamic and electrophoretic light scattering techniques as well as sample preparation, instrument configuration and how to set up standard operating procedures (SOPs).

 

  PTL adds Malvern’s Morphologi G3 to its testing technologies Particle Technology Labs (Chicago, USA) has added the Morphologi G3 from Malvern Instruments to the extensive range of technologies it has available for analyzing its clients' materials. PTL, which is based in Chicago, is a leading service laboratory dedicated to quality particle sizing and characterization