Leica Biosystems, a global leader in anatomic and digital pathology solutions; and Indica Labs, a global leader in artificial intelligence (AI)-powered digital pathology software, have announced that Leica Biosystems has agreed to make a significant strategic investment in Indica Labs. This partnership has the potential to accelerate AI-enabled companion diagnostics (CDx) and support discoveries and treatments based on discrete or complex biomarker expression profiles which are not discernable by the human eye.

Physicists are getting closer to controlling single-molecule chemical reactions – could this shape the future of pharmaceutical research? A new study, published in the prestigious journal Nature Communications, set out to demonstrate for the first time that competing chemical reaction outcomes can be influenced by using the atomic resolution of a scanning tunnelling microscope (STM).

ZEISS partners with Mindpeak, a pioneer in AI-powered pathology solutions, to develop an integrated Multiplex Immunofluorescence (mIF) solution that serves pathologists across research, diagnostics, and clinical applications. Mindpeak’s expertise in AI-based image analysis of pathological tissues, particularly through its established algorithms for clinical routine applications, complements ZEISS's advanced instruments and software for research applications of mIF...

Conducting quality control analysis in-house can offer time-saving benefits and help to control costs and protect confidential information. However, for companies that are not experienced in selecting an appropriate microscope, outsourcing SEM capabilities to a university or laboratory can be a tempting option. Here, Robbie O’Connell, Sales Account Manager (Electron Microscopy) at SEM specialist Thermo Fisher Scientific, offers advice on what to look for when purchasing an SEM for quality control purposes...

Queensgate and the United Kingdom's National Metrology Institute have revealed their latest breakthrough at Euspen’s Special Interest Conference: Precision Motion Systems and Control in November. The development is a novel control system for a two-axis flexure stage with a 100 µm x 100 µm scanning range that enables high-speed atomic force microscopy (HS-AFM) over large areas. The result is an HS-AFM system capable of imaging large areas with molecular-level resolution...

Choosing a film for a movie night is always a battle. Now imagine if you could pick one that provided a window into some of the most fundamental biological processes that keep us alive. For the first time ever, researchers have captured a real-time molecular movie to show how two essential cellular processes – transcription and translation – interact with each other in bacteria...

Bruker Corporation announces the launch of the Dimension Nexus™ atomic force microscope (AFM). Dimension Nexus is the newest addition to the industry‑leading Dimension® AFM product line, which has had more than 4600 systems installed around the world. With the latest‑generation NanoScope® 6 controller, this new small‑footprint AFM delivers wider access to Bruker’s exclusive PeakForce Tapping® technology and over 50 AFM modes...

Jackson ImmunoResearch, a manufacturer of secondary antibodies and immunoreagents for the life science market, announces a new addition to its range of products for scientists seeking to harness the utility of the GFP (green fluorescent protein) tag. GFP is a common fusion protein tag that enables protein expression to be monitored, quantified, and localized within the complex environment of the cell...

TESCAN Group has reopened its existing Tempe R&D facility, adding a laboratory showcasing TESCAN’s latest electron microscopy technologies. The lab features the TESCAN TENSOR STEM and the newly launched Solaris 2 FIB-SEM, offering customers hands-on demonstrations and specialized support in sectors such as Materials Science and Semiconductor R&D, Failure Analysis and Process Monitoring...

Evident recently announced the release of its IXplore™ IX85 automated inverted microscope system. With an industry-leading 26.5mm field number (FN), combined with new advanced imaging tools that ensure clear, accurate results, this new system empowers researchers to capture more data and uncover new insights faster than ever before. It also delivers an unmatched level of customizability, allowing users to design or build an intelligent, high-performance imaging platform that meets their specific goals...

CrestOptics S.p.A., a manufacturer of high-end microscopy solutions and advanced systems for fluorescence microscopy, and Tomocube, a leader in holotomography (HT) technology, today announced a strategic collaboration to provide a next-generation multimodal imaging platform, the HT-X1™ Plus. By combining the expertise of both companies, this platform integrates CrestOptics’ spinning disk confocal technology with Tomocube’s latest innovation...

Spin-out ChromaTwist has won a prestigious Innovate UK Smart grant to co-fund a £0.5m project. The funding from Innovate UK, the UK’s innovation agency, covers 70% of the cost of a project that will take ChromaTwist’s novel dyes to the next level in terms of enhanced brightness and staining indices, to make cells and cellular structures stand out more clearly during bio-imaging...

Linkam Scientific Instruments has announced new updates to its specialist CMS196 cryo-stage. The CMS196V4 supports cryo-correlative light and electron microscopy (cryo-CLEM) and allows researchers to investigate samples at cryogenic temperatures down to < -195 °C. The latest updates to the CMS196V4 stage include an improved user interface featuring a touch-panel and joystick, alongside an encoded and motorised XY stage which allows high-precision automated mapping of sample grid...

These products allow direct coupling of Nikon’s LED light source to stereo microscopes without the need for fiber optics. Stereo microscopes are suitable for observing large samples. To observe detailed internal structures, a technique called "fluorescent observation" is used, in which features of interest are stained with fluorescent proteins such as GFP or fluorescent dyes to highlight them against a dark background. Epi-fluorescence attachments are needed to pass light...

Whether discovering new materials or working to overcome challenges with existing products, scanning electron microscopy (SEM) is a valuable instrument for industry. Here, Britta Siefer, Senior Sales Account Manager at industrial SEM specialist Thermo Fisher Scientific, explains the considerations when investing in an SEM microscope for an industrial application...

Beauty of cosmic proportions found in microscopic imaging. Evident unveiled the winners of its 5th annual Image of the Year contest, an awards competition that recognizes the world’s best in scientific microscopic imaging. The winners were selected from submissions from 29 countries around the world. For the first time, the competition included a video category to showcase the art of capturing small changes in motion under the microscope...

Thermo Fisher Scientific is exhibiting at filtration trade show FILTECH 2024 held from 12-14 November, at the Koelnmesse Halls in Cologne, Germany. Leaders and technical experts from Thermo Fisher will be present to offer expertise in electron microscopy and discuss how this technique  provides an advanced solution, optimising material analysis for filtration...

A new imaging technique could mean patients with aggressive brain tumours benefit from cutting edge immunotherapy treatments, according to researchers. A team from The Institute of Cancer Research, London, has developed a new immuno-PET imaging technique that could spot which glioblastoma patients would respond well to immunotherapy, and track the response over time...

Leica Microsystems, a leader in microscopy and scientific instrumentation, has released SpectraPlex, a 3D high-multiplex solution for spatial discoveries on the STELLARIS confocal platform. This groundbreaking innovation sets a new benchmark for 3D spatial phenotyping in life science research. In recent years, Omics techniques – Genomics, Transcriptomics, Proteomics, and Metabolomics – have taken a central role in life science research...