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Microsaic Systems Exhibits the World’s Smallest MS System at Analytica 2012

publication date: Mar 9, 2012
author/source: The Scott Partnership Ltd
Microsaic 3500 MiDMicrosaic Systems plc, the high technology company developing next generation mass spectrometry instruments, is to exhibit the Microsaic 3500 MiD at Analytica 2012, Munich, 17th - 20th April 2012, Hall A2, Booth 240. Developed in collaboration with three major pharmaceutical companies, the 3500 MiD® is the world's first chip-based mass spectrometer  is an extremely robust system which is simple and intuitive to use. 90% smaller than conventional mass spectrometers and with fewer infrastructure requirements, the revolutionary Microsaic 3500 MiD is a versatile, portable solution for bench chemists in medicinal chemistry laboratories. Able to be configured and ready to use in one hour, the drastically reduced footprint and ease of use means the 3500 MiD is the ideal mass spectrometer for the modern laboratory.

Microsaic Systems has successfully transformed mass spectrometry by integrating key miniaturised components onto patented chip technologies called ionchip®, spraychip®, and vac-chip. The core technologies are chip-scale versions of traditional mass spectrometry components which can be interchanged rapidly by the user, enabling greater adaptability and speed of use. The 3500 MiD is the only MS system on the market which does not require an external vacuum pump, and is significantly smaller than legacy systems.  The ability to control the 3500 MiD remotely via a LAN connection removes the need for a monitor or keyboard next to the system, further minimizing the footprint, meaning the product is small enough to sit inside a fume hood. Previously, MS had only been used for off-line analysis but with the 3500 MiD MS analysis can be now performed on-line within the fume-hood.

The 3500 MiD is designed to integrate with existing HPLC equipment with no extra footprint and no infrastructure requirements (e.g. sound proofing, A/C). Other separation methods such as Prep LC, Flash LC and SFC can also be combined with the 3500 MiD to offer mass directed purification. The ability to monitor reactions in real time provides the chemist with vital data which can be acted upon to rapidly speed up reaction optimisation, improve safety and save valuable time.

The company's products retain the functionality of larger conventional MS systems but are considerably smaller, lighter, consume less energy and operate at only 10% of the standard running costs. The highly innovative modular approach enables users to maintain the system without the need for expensive service contracts and time consuming call outs. Users are able to increase the use of mass spectrometry in the lab while benefiting from significant cost savings owing to fewer necessary structural components such as gas generators and air conditioning. There are also sizeable savings with the use of ‘Plug and Play' components which enable users to maintain the system themselves, resulting in less downtime and greater flexibility within the laboratory.

"Microsaic Systems has revolutionised MS by developing the world's first chip based mass spectrometer," said Professor Eric Yeatman, Acting CEO of Microsaic Systems. "The 3500 MiD is compatible with a wide range of methods, flow rate and solvents. The ‘plug and play' chips make the 3500 MiD configurable, flexible and future proof and its greatly reduced footprint means mass spectrometry is now more accessible to more laboratories than ever before."

For more information about the Microsaic 3500 MiD system, please visit the Microsaic Systems booth at Hall A2 - Booth 240, Analytica 2012. Alternatively please call +44 1483 751 577, email or visit

About Microsaic Systems plc

Microsaic Systems plc is a high technology company developing and marketing next generation mass spectrometry (MS) instruments for the analysis of gaseous, liquid and solid samples. Microsaic has successfully miniaturised mass spectrometry by integrating the key MS components onto patented chip technologies called ionchip®, spraychip® and vac-chip. Microsaic's MS products retain the speed and sensitivity of larger, conventional MS systems but are substantially smaller, lighter, consume less energy and have lower running costs. The Company's first product, the Microsaic 3500 MiD®, was launched in January 2011 and is the world's smallest MS system.

Microsaic Systems plc was established in 2001 to develop miniaturized MS instruments based on Micro-Electrical-Mechanical Systems (MEMS) originating at the highly regarded Optical and Semiconductor Devices Group at Imperial College London. Microsaic has subsequently established a large portfolio of 88 patents, of which 36 are granted. The Company has been based at headquarters in Woking, UK since September 2004 and was admitted to AIM, a market of the London Stock Exchange, in April 2011 (ticker: MSYS).

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