Follow us...

 

Search News Archives

Channels

News

 

 

View Channel

Laboratory Products

 

 

View Channel

Special Offers and Promotions

 

Microscopy | Image Analysis

 

 

View Channel

Separation Science

 

 

View Channel

Coronavirus (COVID-19)

 

 

View Channel

Research & Case Studies

 

 

View Channel

Conferences | Events

Malvern discusses complementary techniques for OINDP analysis at DDL 21

Morphologi (left) and Spraytec systems from Malvern InstrumentsAs well as exhibiting at this year's Drug Delivery to the Lungs conference (DDL21; 8-10 Dec 10; Edinburgh, Scotland), specialists from Malvern Instruments will present a scientific poster "Characterizing a nasal spray formulation from droplet to API particle size", which examines the complementarity of automated image analysis and laser diffraction for characterizing nasal spray formulations. 

Nasal spray deposition relates to the droplet size that is delivered while bioavailability depends on a  number of factors, significant among which is the size distribution of the API. Laser diffraction analysis using Malvern's Spraytec system enables the monitoring of changes in droplet size, and can be used to investigate the robustness of the delivery system. Image analysis with Malvern's Morphologi G3-ID, which integrates automated size/shape analysis of particles with the chemical identification provided by Raman spectroscopy, permits the detection of even subtle changes in API size distribution. Such changes can be brought about by the spray process itself and potentially may affect bioavailability .  

These two highly complementary techniques have applications for a variety of inhaled products. Dry powder inhaler development, which demands detailed study of the dynamics of powder entrainment and dispersion, as well as an understanding of the structure of the delivered particles, offers another example. Techniques which can follow the process of particle dispersion, and then identify which species have been dispersed to a respirable particle size, can offer significant benefits, especially when developing new combination therapies. 

For further informationplease visit www.malvern.com/spraytec_oindp  



 

Subscribe to any of our newsletters for the latest on new laboratory products, industry news, case studies and much more!

Newsletters from Lab Bulletin

 

Request your free copies HERE

 

 

 

Popular this Month

Top 10 most popular articles this month

 

Today's Picks

 

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd.


 

Media Partners