BioTek Instruments continues to expand its Synergy^TM Multi-Mode Microplate Reader family with the introduction of the patent-pending Synergy H4 with Hybrid Technology^TM. Synergy H4 combines the sensitivity of filter-based optics with the flexibility of monochromator-based optics in one compact instrument for high-performance fluorescence-based applications. This unique hybrid of both technologies provides for endless flexibility in current and future microplate-based assay choice. Additionally, Synergy H4 is compatible with BioTek's Take3^TM Multi-Volume Plate for low-volume measurements down to 2 µL.

Filter/dichroic-based fluorescence optics provide superior light filtering and purification with fast wavelength switching and read speeds. This exceptional performance is perfect for demanding applications including TR-FRET, fluorescence polarization or AlphaScreen^®/AlphaLISA^®. 

Quadruple monochromator-based fluorescence optics provide the flexibility to choose any wavelength from the UV to the near infrared for a broad range of applications; and the variable bandpass selection system is ideal for spectral scanning applications. Top and bottom optics enhance assay flexibility even further. 

"Many laboratories have varying assay requirements, from simple biochemical assays to complex cell-based assays," noted Xavier Amouretti, BioTek Instruments Product Manager. "The Hybrid Technology in our Synergy H4 allows the lab to get the best of all worlds for both current and future assays. It's like having two instruments for the price of one." 

Synergy H4 is modular, and the fully equipped configuration may be used for fluorescence intensity/FRET, time-resolved fluorescence (TRF) and TR-FRET, fluorescence polarization, AlphaScreen/AlphaLISA, Luminescence and UV-Visible Absorbance. 

BioTek Instruments, Inc., headquartered in Winooski, VT, USA, is a worldwide leader in the design, manufacture, and sale of microplate instrumentation and software. BioTek instrumentation is used to aid in the advancement of life science research, facilitate the drug discovery process and to enable cost-effective quantification of disease relevant molecules in the clinic.