Follow us...

 

Search News Archives

News Channels

 

New Laboratory Products

Lab News

What's going on at Lab Innovations

Research & Case Studies

Microscopy | Image Analysis

Separation Science

Brochures & Literature

Videos

Events | Webinars

 

 

Conferences | Events

Avacta Announces CAR-T Cell Therapy Research Collaboration with Major US Cancer Centre

publication date: Nov 14, 2016
 | 
author/source: Avacta Life Sciences

Avacta Group plc (AIM: AVCT), the developer of Affimer® biotherapeutics and research reagents announces a research collaboration with Memorial Sloan Kettering Cancer Center (MSK) to evaluate the use of Avacta’s Affimer technology in novel CAR-T cell-based immunotherapy.

AvactaCAR-T immunotherapy is a form of cancer treatment in which the patient’s own immune system T cells are modified to give them greater potency with which to attack cancer cells .Treatments using these engineered immune cells have generated promising responses in patients with advanced cancers and CAR-T immunotherapy has become an intense area of research, clinical development and investment. 

The simple structure and biophysical properties of Affimers potentially provide significant advantages over antibody fragment technology currently used in CAR-T cell modification and the collaboration announced today is intended to demonstrate a new class of CAR-T cell therapy that incorporate Affimer molecules.

The collaboration will be led by Renier J. Brentjens, MD, PhD, Director of Cellular Oncology at Memorial Sloan Kettering Cancer Center in New York.

As part of the collaboration Avacta will develop Affimer molecules that bind different regions of CD19, a surface protein specific to B-cells involved in lymphomas. Dr Brentjens’ team will construct CAR-T cells incorporating these Affimer molecules and test

Under the terms of the agreement the ownership of the results generated directly as part of this collaboration will be shared between Avacta and MSK.

Dr Alastair Smith, Chief Executive Officer, Avacta, commented:  “CAR-T cell therapy is an emerging and very exciting area of immuno-oncology which holds enormous clinical potential. We are delighted to be working with a world-leading team in the field to demonstrate the benefits that Affimer technology could bring to CAR-T therapy.  The generation of positive data in these validated models of disease has the potential to open up highly valuable licensing and partnering opportunities for Avacta in this therapy area which has attracted so much attention in the past couple of years.”


more about avacta


more news from avacta


 


If you have not logged into the website then please enter your details below.



 

 

Popular this Month...

Our Top 10 most popular articles this month

 

Today's Picks...

 

 


 

Looking for a Supplier?

Search by company or by product

 


Company Name:

Product:


 

 

Please note Lab Bulletin does not sell, supply any of the products featured on this website. If you have an enquiry, please use the contact form below the article or company profile and we will send your request to the supplier so that they can contact you directly.

Lab Bulletin is published by newleaf marketing communications ltd

 


Promotions

 

Media Partners