Analytical Services International (ASI) at St George's, University of London, UK, has been evaluating LoGiCal certified reference materials - a new product range from LGC Standards - for its therapeutic drug monitoring (TDM) services, where high quality reference standards are an essential requirement. The use of high quality reference materials is equally important for the Company's international proficiency testing scheme for immunosuppressive drugs, co-ordinated by Professor David Holt. ASI recently validated the use of LoGiCal solutions of the immunosuppressant mycophenolic acid (MPA) and antiarrhythmic amiodarone metabolite desethylamiodarone (DEA) in its assays. 

Michelle Moreton-Clack, TDM Service Manager, explained: "As part of our therapeutic drug monitoring service, we run assays for the measurement of MPA and DEA. We usually buy the drugs in powder form and weigh them out to prepare stock solutions for our assays. The LoGiCal range includes ISO Guide 34 certified solutions of MPA and DEA, which are really easy to use and save a lot of time by eliminating weighing stages. We validated both compounds against our existing stock solutions, and they showed good correlation; I am very pleased with the results." 

To learn more about the LoGiCal product range, visit www.LoGiCal-Standards.com  

To learn more about TDM at Analytical Services International, visit www.bioanalytics.co.uk/routine_assays.html