The gold standard in dsRNA detection now available to virology researchers worldwide

Absolute Biotech, a new company uniting multiple antibody-centric brands into a single organization specializing in antibody reagents, kits and services announces the reintroduction of SCICONS™ dsRNA antibodies. Originally developed in 1990, SCICONS antibodies have become the gold standard in double-stranded RNA detection, with hundreds of peer-reviewed citations characterizing their use in a diverse range of applications. The antibodies are now available to scientists worldwide through Absolute Biotech, with offerings including the original clones, ELISA kits and recombinant engineered antibody formats.

The SCICONS antibodies are used to detect dsRNA intermediates of a wide range of viruses, including chikungunya, dengue, hepatitis, rabies, rhinovirus, polio, swine fever and more. The antibody clones – J2, J5, K1 and K2 – are highly specific and lack reactivity with DNA and single-stranded RNA. They have been extensively applied by virology researchers and mRNA vaccine developers to study the viral life cycle and anti-viral responses, as well as used as a diagnostic tool to detect whether an unknown pathogen is bacterial or viral.

In addition to the original mouse monoclonal antibodies, Absolute Biotech offers the antibodies packaged into ELISA kits as well as recombinantly produced formats. The antibodies are available off-the-shelf in different species and isotypes, as well as unique formats such as Fc silenced and His-tagged Fab fragments, with other formats available upon request.

“We’re excited to reintroduce SCICONS™ dsRNA antibodies to the global scientific community, with a new look and next-generation options, using the same dsRNA technology that has been trusted for decades,” said Dr. Ed Horton, Chief Commercial Officer of Absolute Biotech. “It’s a great example of why Absolute Biotech was founded, to bring together unique product portfolios and wide-ranging antibody expertise to deliver reagents that empower scientists.”

The dsRNA manufacturer SCICONS was purchased by Nordic-MUbio in 2021 and made available through their US partner Exalpha. In 2022, Nordic-MUbio and Exalpha became part of Absolute Biotech.

Learn more about the SCICONS™ dsRNA antibodies and ELISA kits.

About Absolute Biotech

Absolute Biotech specializes in antibody reagents, kits and services, adding value to existing antibodies through annotation, validation, sequencing, engineering and recombinant manufacturing. Our company unites multiple antibody-centric brands to offer customers worldwide the full breadth of antibody-related products, services and expertise for research, diagnostic and therapeutic applications. Our mission is to serve as “antibody curators” for customers worldwide, treating each antibody like a work of art to deliver unique and absolutely defined reagents that empower scientists.

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