A miniature, chemically inert Stepper Dispense Pump which is designed to deliver variable micro-litre volumes in the 50µL to 250µL range with a consistent performance yet in the most compact package, has been introduced by LEE PRODUCTS.
The LPD Series pump has been developed to offer greater design flexibility and significant cost-savings to the medical and scientific industries as a result of its maintenance-free design. It can be located wherever fluidic requirements dictate, regardless of maintenance accessibility. The pump is offered in both standard and high performance models, with the latter incorporating a home sensor, encoder and backlash compensation for more demanding applications and provides a CV of ≤ 0.01% at...
Metrohm launches the 884 Professional VA, a fully integrated measuring system for voltammetry, polarography, and cyclic voltammetric stripping (CVS).
The system’s entirely modular design (including a readily exchangeable measuring head for fast switching between methods) and powerful viva software make the 884 Professional VA the preferred tool for the determination of transition metals, organic compounds, (heavy) metal speciation analysis, and the determination of organic additives in electroplating solutions.
Genevac has announced that its popular miVac SpeedTrap cold trap can now be used for freeze drying or configured as a combined concentration / freeze drying workstation with a miVac vacuum concentrator.
Utilising the updated miVac SpeedTrap with continuous chill mode in conjunction with the miVac Super Vacuum pump, up to 250ml of water, or other solvents such as 1,4- dioxane, may be freeze dried in a single operation. Samples to be dried are simply placed in the rotor of the miVac concentrator and dried at full vacuum. The vacuum boils the samples at below their freezing point, therefore the samples freeze and the ice sublimes away, leaving the sample as a dry powder. To reduce drying times a...
Microbiology specialist Lab M has been following the Food Standards Agency’s year-long survey of campylobacter in fresh chickens sold in the UK.
Campylobacter is the UK’s leading cause of food poisoning and the survey results published on 28 May 2015 (http://www.food.gov.uk/news-updates/news/2015/14003/campylobacter-survey-results-12months ) show that 73% of chickens tested positive for the presence of campylobacter, with one in five (19%) testing positive within the highest band of contamination . “As a company we work closely with microbiologists in the...
Specialised Imaging has produced a presentation that delivers an informative and unbiased review of the historical development of ultra high-speed imaging technology.
The first practical application of high-speed imaging was Eadweard Muybridge’s 1878 photographic investigation into whether a horses' feet were actually all off the ground at once during a gallop. The first photograph of a supersonic flying bullet was taken by the Austrian physicist Peter Salcher in 1886, a technique that was later used by Ernst Mach in his studies of supersonic motion. German weapons scientists later applied these high speed imaging...
Markes International (Llantrisant, UK) has announced the launch of a new web-based application that will allow users to discover how ‘soft’ electron ionisation technology could benefit their GC–MS application.
The new resource, hosted at www.select-ev.com, will allow anyone to view time-of-flight mass spectra generated using Markes’ Select-eV technology. The library has been launched with the 70 eV and low-eV spectra of over 350 compounds, but will be updated quarterly with curated spectra acquired in Markes’ laboratories, as well as from Select-eV users around the world. Laura McGregor, TOF MS Product Marketing Manager at Markes International...
Syngene, a world-leading manufacturer of image analysis solutions is delighted to announce the appointment of Matthew Dunne, as its new International Sales Manager.
The firm has appointed Matthew at this time to capitalise on the increasing demand for quality assured gel imaging systems, especially in the Middle East and Asia Pacific regions. Matthew comes to Syngene with a wealth of experience, having been active in sales management and sales for life science product suppliers, including a major international gel documentation company for over 16 years. His imaging expertise is supported by a masters...
Lonza has today released the latest addition to its L7™ hPSC System, a robust, streamlined and comprehensive platform for the generation of human induced pluripotent stem cells (hiPSCs) and the maintenance of stem cells from a variety of sources.
The new L7™ PBMC Reprogramming Bundle slots seamlessly into the existing L7™ workflow to enable researchers to reprogram peripheral blood mononuclear cells (PBMCs) for use in downstream experiments. Because of its series of reagents and protocols optimized for working specifically with PBMCs, the new bundle makes it easier and faster to generate hiPSCs. The L7™ hPSC System offers a complete workflow that combines primary cells...
Quotient Clinical, the Translational Pharmaceutics® Company, has announced the successful completion of an Enabled-First-in-Human® (Enabled-FIH) program for US biotech company Corcept Therapeutics Incorporated, focusing on a next generation selective glucocorticoid receptor antagonist (CORT125134) in development for the treatment of Cushing’s syndrome and certain cancers.
The Enabled-FIH program integrated formulation development, real-time GMP manufacturing and clinical testing, using a single adaptive protocol to assess single and multiple dose safety, pharmacokinetics, and proof of pharmacological effect. The clinical timeline for the first-in-human dose through to completion of the program was only 7 months. CORT125134 was proven to be safe and well tolerated at the doses tested, and pharmacological effect...
Setting up your own high quality, customised immunoassay solutions just became quicker, easier and more cost-effective. The new range of distinctive, top-quality, pre-matched capture and detection antibody pairs manufactured by BioPorto is now available from Alpha Laboratories. Each pair consists of a capture antibody and biotinylated detection antibody, custom matched to provide the best results and give you confidence in the quality of your assay...
Scientists have identified a gene mutation linked to the development of an aggressive form of brain cancer.
Researchers found that errors in a gene known as TCF12 – which plays a key role in the formation of the embryonic brain are associated with more aggressive forms of a disease called anaplastic oligodendroglioma. The new research is the largest ever genetic study of oligodendrogliomas, and provides important insights into their causes – and how they might be treated. Oligodendrogliomas are fast-growing cancers that account...
Renishaw, a world leader in metrology and spectroscopy technologies, announce their participation at MMC 2015, which takes place from 29th June to 2nd July 2015 at the Manchester Central Convention Complex, Manchester, UK.
Renishaw Applications Scientist, Dr Katherine Lau, will make a presentation as part of the conference program and lead a workshop on Raman confocal microscopic imaging. MMC 2015, incorporating EMAG 2015, is hosted by the Royal Microscopical Society and takes place from 29th June to 2nd July 2015, at the Manchester Central Convention Complex, Manchester, UK. During this exhibition and conference, Applications Scientist, Dr Katherine Lau...
The VIDA™ 80H by PAC is a fully automated reliable density analysis meter that works on an advanced osciallating stainless steel u-tube technology that offers an incredibly simple and easy approach to obtaining highly reliable density measurements.
VIDA™ 80H is user-friendly, easy to set up and use and fully automated, so it doesn’t require a highly-trained operator. Designed to be a true "push-button" solution, it is powered by smart software that automates every step of the test sequence – from sample injection to data reporting - allowing minimal operator attendance. The meter is equipped with a patented auto injection and bubble dectection technology that delivers highly accurate...
The extensive MZR range of low flow, miniature, positive displacement micro annular gear pumps provide precise, accurate and smooth, low pulse pumping and dispensing of a wide variety of liquids, including low and high viscosity fluids.
Designed and manufactured to the highest standards by HNP Mikrosysteme in Germany and distributed in the UK by MICHAEL SMITH ENGINEERS, the ultra-compact size and low mass of these pump and motor units ensure that they can be easily incorporated into the designs of many systems and are well suited to OEM applications. The range comprises six series of pumps, all of which provide smooth, accurate, virtually pulse-free liquids...
Abcam plc, a global leader in the supply of life science research tools, announced today the launch of a range of multiplex miRNA profiling assays for high-throughput validation of miRNA biomarkers, based on Abcam’s new Firefly™ particle technology.
The new Multiplex Cellular miRNA Assay and Multiplex Circulating miRNA Assay allow researchers to rapidly and cost-effectively profile up to 68 miRNAs in each well of a 96-well plate, with readout on a standard flow cytometer. These assays offer an easier workflow for larger sample numbers compared to alternative methods such as qPCR, microarray and sequencing, which can be resource intensive or require challenging data analysis. The Multiplex Circulating...
New smart fluorescence live cell movie analyser and counter.
JuLI™ FL uses novel optics to capture live-cell images from various cell culture dishes. It can perform cell- based assays, including cell counting, cell viability and GFP/RFP expression level checking. This The JuLI™ FL, from Nanoentek is the next generation, smart fluorescence live cell movie analyser and counter. The gives the user quantified cell confluence results with low variation and growth curve data....
In parallel chemistry, cross contamination is always a key concern. Genevac evaporators have been designed from the outset to withstand the rigors of working in the chemistry laboratory and to be resistant to the most common solvents and acids used.
The unique Dri-Pure anti-bumping system prevents cross contamination by preventing solvent bumping. With pre-programmed monitoring methods, and automatic stop systems, this frees someone up to perform other functions, increasing not just productivity but performance and results....
The Institut Curie (Paris, France), a world leader in oncology research, has reported how it has standardised on using MEDIACLAVE media preparation and MEDIAJET automated petri dish filling systems from INTEGRA Biosciences to prepare its petri dishes.
Research work at the Institut Curie requires petri dishes for a wide range of applications including growing bacteria, yeasts and moulds, making it necessary to regularly produce 10 to 12 different types of media in varying quantities (from one to several litres). The assurance of reliable, high throughput production of these petri dishes, free of any contamination, is critical to ongoing research work. Fatima Dekmous, Departmental Head of the Wash facility at Institut Curie commented...
VICI’s Microvolume Diaphragm Valve is designed for trouble-free use in applications requiring minimal maintenance and maximum lifetime, making it the ideal choice for the process industry, automated lab analyzers, and continuous-monitoring environmental analyses.
Three configurations are available: a 4 port internal loop sample injector; a 6 port external loop sampling/switching valve; and the industry’s first 10 port multifunctional diaphragm valve. Lifetime for the DV22 can exceed 1,000,000 cycles at ambient temperature/300 psi or 500,000 cycles at 175°C/300 psi. The standard valve is for applications in which the sample is above ambient pressure, but it can also be used with sub-ambient pressures...
UniFlow LE Fume Hood 96” is constructed to meet all explosion proof specifications for classified locations.
The intrinsically safe airflow alarm that continuously monitors the face velocity is explosion proof with a hot wire sensor. The hood is constructed entirely of chemical resistant, non-conductive, flame retardant, non-metallic composite resin materials (no rust) and features an exclusive “Unitized” construction that does not require screws, bolts, rivets, or metallic hardware to assemble. The fume chamber is molded one piece seamless with all...
Microscopy tools optimized for use with emerging neurotechnologies provided for researchers
ZEISS announces that it is participating in a new public-private partnership with UC Berkeley as part of the Brain Microscopy Innovation Center (BrainMIC), a component of the Berkeley BRAIN Initiative. The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative was launched by President Obama in 2013 and is focused on revolutionizing understanding of the human brain, with the goal of helping researchers uncover the...
Horizon Discovery Group plc (LSE:HZD), the international life science company supplying research tools and services that power genomics research and the development of personalized medicines, and DefiniGEN Ltd, a leading provider of stem cell products and services, today announced their collaboration to develop a range of unique, gene-engineered iPS (induced pluripotent stem)-based cell lines for use in research.
Under the terms of the agreement, Horizon will perform genome engineering on the iPS cells, which will then be differentiated by DefiniGEN. The project will initially focus on generation of ten iPS-based cell lines for research in areas that currently lack high quality disease models. The resulting cell lines will be cultured, differentiated and quality controlled by DefiniGEN to ensure that scientists receive uniform cell populations suited to their experiments...
The LPD Series pump has been developed to offer greater design flexibility and significant cost-savings to the medical and scientific industries as a result of its maintenance-free design. It can be located wherever fluidic requirements dictate, regardless of maintenance accessibility. The pump is offered in both standard and high performance models, with the latter incorporating a home sensor, encoder and backlash compensation for more demanding applications and provides a CV of ≤ 0.01% at...
Utilising the updated miVac SpeedTrap with continuous chill mode in conjunction with the miVac Super Vacuum pump, up to 250ml of water, or other solvents such as 1,4- dioxane, may be freeze dried in a single operation. Samples to be dried are simply placed in the rotor of the miVac concentrator and dried at full vacuum. The vacuum boils the samples at below their freezing point, therefore the samples freeze and the ice sublimes away, leaving the sample as a dry powder. To reduce drying times a...
Campylobacter is the UK’s leading cause of food poisoning and the survey results published on 28 May 2015 (http://www.food.gov.uk/news-updates/news/2015/14003/campylobacter-survey-results-12months ) show that 73% of chickens tested positive for the presence of campylobacter, with one in five (19%) testing positive within the highest band of contamination . “As a company we work closely with microbiologists in the...
The first practical application of high-speed imaging was Eadweard Muybridge’s 1878 photographic investigation into whether a horses' feet were actually all off the ground at once during a gallop. The first photograph of a supersonic flying bullet was taken by the Austrian physicist Peter Salcher in 1886, a technique that was later used by Ernst Mach in his studies of supersonic motion. German weapons scientists later applied these high speed imaging...
The new resource, hosted at www.select-ev.com, will allow anyone to view time-of-flight mass spectra generated using Markes’ Select-eV technology. The library has been launched with the 70 eV and low-eV spectra of over 350 compounds, but will be updated quarterly with curated spectra acquired in Markes’ laboratories, as well as from Select-eV users around the world. Laura McGregor, TOF MS Product Marketing Manager at Markes International...
The firm has appointed Matthew at this time to capitalise on the increasing demand for quality assured gel imaging systems, especially in the Middle East and Asia Pacific regions. Matthew comes to Syngene with a wealth of experience, having been active in sales management and sales for life science product suppliers, including a major international gel documentation company for over 16 years. His imaging expertise is supported by a masters...
The new L7™ PBMC Reprogramming Bundle slots seamlessly into the existing L7™ workflow to enable researchers to reprogram peripheral blood mononuclear cells (PBMCs) for use in downstream experiments. Because of its series of reagents and protocols optimized for working specifically with PBMCs, the new bundle makes it easier and faster to generate hiPSCs. The L7™ hPSC System offers a complete workflow that combines primary cells...
The Enabled-FIH program integrated formulation development, real-time GMP manufacturing and clinical testing, using a single adaptive protocol to assess single and multiple dose safety, pharmacokinetics, and proof of pharmacological effect. The clinical timeline for the first-in-human dose through to completion of the program was only 7 months. CORT125134 was proven to be safe and well tolerated at the doses tested, and pharmacological effect...
Setting up your own high quality, customised immunoassay solutions just became quicker, easier and more cost-effective. The new range of distinctive, top-quality, pre-matched capture and detection antibody pairs manufactured by BioPorto is now available from Alpha Laboratories. Each pair consists of a capture antibody and biotinylated detection antibody, custom matched to provide the best results and give you confidence in the quality of your assay...
Researchers found that errors in a gene known as TCF12 – which plays a key role in the formation of the embryonic brain are associated with more aggressive forms of a disease called anaplastic oligodendroglioma. The new research is the largest ever genetic study of oligodendrogliomas, and provides important insights into their causes – and how they might be treated. Oligodendrogliomas are fast-growing cancers that account...
Renishaw Applications Scientist, Dr Katherine Lau, will make a presentation as part of the conference program and lead a workshop on Raman confocal microscopic imaging. MMC 2015, incorporating EMAG 2015, is hosted by the Royal Microscopical Society and takes place from 29th June to 2nd July 2015, at the Manchester Central Convention Complex, Manchester, UK. During this exhibition and conference, Applications Scientist, Dr Katherine Lau...
VIDA™ 80H is user-friendly, easy to set up and use and fully automated, so it doesn’t require a highly-trained operator. Designed to be a true "push-button" solution, it is powered by smart software that automates every step of the test sequence – from sample injection to data reporting - allowing minimal operator attendance. The meter is equipped with a patented auto injection and bubble dectection technology that delivers highly accurate...
Designed and manufactured to the highest standards by HNP Mikrosysteme in Germany and distributed in the UK by MICHAEL SMITH ENGINEERS, the ultra-compact size and low mass of these pump and motor units ensure that they can be easily incorporated into the designs of many systems and are well suited to OEM applications. The range comprises six series of pumps, all of which provide smooth, accurate, virtually pulse-free liquids...
The new Multiplex Cellular miRNA Assay and Multiplex Circulating miRNA Assay allow researchers to rapidly and cost-effectively profile up to 68 miRNAs in each well of a 96-well plate, with readout on a standard flow cytometer. These assays offer an easier workflow for larger sample numbers compared to alternative methods such as qPCR, microarray and sequencing, which can be resource intensive or require challenging data analysis. The Multiplex Circulating...
JuLI™ FL uses novel optics to capture live-cell images from various cell culture dishes. It can perform cell- based assays, including cell counting, cell viability and GFP/RFP expression level checking. This The JuLI™ FL, from Nanoentek is the next generation, smart fluorescence live cell movie analyser and counter. The gives the user quantified cell confluence results with low variation and growth curve data....
Research work at the Institut Curie requires petri dishes for a wide range of applications including growing bacteria, yeasts and moulds, making it necessary to regularly produce 10 to 12 different types of media in varying quantities (from one to several litres). The assurance of reliable, high throughput production of these petri dishes, free of any contamination, is critical to ongoing research work. Fatima Dekmous, Departmental Head of the Wash facility at Institut Curie commented...
Three configurations are available: a 4 port internal loop sample injector; a 6 port external loop sampling/switching valve; and the industry’s first 10 port multifunctional diaphragm valve. Lifetime for the DV22 can exceed 1,000,000 cycles at ambient temperature/300 psi or 500,000 cycles at 175°C/300 psi. The standard valve is for applications in which the sample is above ambient pressure, but it can also be used with sub-ambient pressures...
The intrinsically safe airflow alarm that continuously monitors the face velocity is explosion proof with a hot wire sensor. The hood is constructed entirely of chemical resistant, non-conductive, flame retardant, non-metallic composite resin materials (no rust) and features an exclusive “Unitized” construction that does not require screws, bolts, rivets, or metallic hardware to assemble. The fume chamber is molded one piece seamless with all...
ZEISS announces that it is participating in a new public-private partnership with UC Berkeley as part of the Brain Microscopy Innovation Center (BrainMIC), a component of the Berkeley BRAIN Initiative. The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative was launched by President Obama in 2013 and is focused on revolutionizing understanding of the human brain, with the goal of helping researchers uncover the...
Under the terms of the agreement, Horizon will perform genome engineering on the iPS cells, which will then be differentiated by DefiniGEN. The project will initially focus on generation of ten iPS-based cell lines for research in areas that currently lack high quality disease models. The resulting cell lines will be cultured, differentiated and quality controlled by DefiniGEN to ensure that scientists receive uniform cell populations suited to their experiments...