Chromatrap, a business unit of Porvair Sciences, announces a new patented protocol that is able to simply, quickly and efficiently enrich transcription factors from Native Chromatin.
Native Chromatin Immunoprecipitation (N-ChIP) is an alternative to traditional cross-linked (X-ChIP), which removes the need for fixing cells with formaldehyde prior to extraction. As a consequence the cells remain in a more natural 'native state'. The DNA/protein fragments are selectively immunoprecipitated using antibodies directed against the protein of interest and the resulting fractions treated to separate the DNA and...
Protagen AG, a company concerned with the development of advanced diagnostic tools to address some of the most severe autoimmune diseases, has today announced that it will join the RA-MAP Consortium.
The overarching goal of the Consortium is to identify the key predictors of clinical response and remission in RA patients, and to identify those individuals at high risk of developing Rheumatoid Arthritis (RA). RA is one of the most common auto-immune diseases in the world. RA patients may experience difficulties with everyday tasks and restricted work options. Thus, RA has massive health economic implications. Early intervention...
Myeloma UK and the Structural Genomics Consortium (SGC) have entered into an open-access research partnership to discover and characterise novel drug targets for myeloma using structural biology and chemical proteomics.
In this first partnership of its kind in Europe, Myeloma UK and the SGC have explicitly agreed not to file for patents on any of the collaborative research and to make all reagents and knowledge available without restriction to the wider research community, including pharmaceutical, biotech, and academic research groups. As part of the collaboration, Myeloma UK will support scientists at the SGC to generate biology data and...
With its range of innovative features, the Stuart range of Undergrad Hotplate stirrers already has a proven track record.
Features including a mains independent hot warning light, which continues to function once the unit is switched off and even unplugged. Our unique LED temperature indicator which progressively illuminates to show the surface temperature. Compatibility with retort rods or stands, compact footprint and smart storage solutions.The entire range of Undergrad hotplates and hotplate stirrers are also compatible with the Stuart SCT1 temperature controller, enabling accurate sample temperature control....
Our world is becoming more environmentally aware with recycling being considered a necessity both domestically and commercially.
Anybody working in a laboratory and using pipettes and tips knows how much waste tip racks produce, how expensive they are to dispose of and the amount of space these used racks can take up. For most labs the cost of running a recycling scheme can be prohibatory as they tend to be priced upon the weight of the plastic being recycled.
The Priorclave Q63, 320 litre front loading capacity autoclave has given laboratories a real opportunity to consider this more economically priced cylindrical chamber design rather than investing in a large rectangular chamber steam steriliser. Users of the Q63 autoclave may also benefit from lower overall running costs associated with reduced power and water usage.
Since chamber size has a major influence on autoclave selection, Priorclave designed the cylindrical chamber of the Q63 with a taller profile than that found in most ‘cylindrical’ machines, giving these autoclaves an impressive load capacity ideally suited to sterilising larger bulky items as well as enabling small and taller items could be sterilised in a single process.
Read MoreFree Techne Water bathFeb 24, 2016
For a limited time only Techne are offering a free water bath with every TE-10D thermoregulator purchased, saving up to £380.
The Techne TE-10D thermoregulator can be used to heat and circulate liquids from ambient to 120°C and being a thermoregulator they also offer excellent temperature stability of +/-0.01°C at 40°C. The entire range comes with a bright 4 digit LED temperature display and are ideal for routine laboratory applications. Safety features include an automatic cut-out when low liquid levels are reached and a user adjustable over-temperature cut-out....
With courses delivered by world-renowned experts including John Dolan, Mel Euerby, Mark Powell, Diane Turner, Alan McKeown, Geoff Pickerell, Brian Montgomery, Helen Poole, Gemma Lo and Annette Larder, the new 2016 Hichrom training calendar is now available! Whether you are a relative newcomer to chromatography or a seasoned veteran, you can benefit from one of our courses.
Our courses will show you how to decrease costs, increase throughput, prevent costly method problems occurring, transfer methods between laboratories or from HPLC to UHPLC and develop faster, more reproducible HPLC/UHPLC or GC assays in a time effective manner. In fact, all of these courses are guaranteed to increase productivity and efficiency in your laboratory, reducing your analysis costs. If this doesn’t happen Hichrom will happily refund your money! New scheduled courses for 2016 include Data Integrity and CIM Monolith Chromatography for Biomolecules....
Ingenza is using its proprietary inABLE® technology to help develop a robust, versatile platform for the production of cyclic peptides for therapeutic use.
This work is part of a collaboration with researchers at the University of Aberdeen and the University of St Andrews, as Professor Marcel Jaspars of the Marine Biodiscovery Centre at the University of Aberdeen explained: “Small molecule drugs, such as paracetamol, are cheap, easy to administer and readily available. At the other end of the scale are large biologics such as antibodies, which have to be administered by injection and may require patients to attend hospital for treatment....
Read MoreNew HALO-2 Peptide Columns: The Sharpest LC Tool for the Sharpest LC PeaksFeb 23, 2016
Advanced Materials Technology have launched a new tool in the BioClass Fused-Core HPLC/UHPLC columns family specifically designed for fast, high-resolution separations of peptides.
These HALO-2 Peptide columns are packed with 2 µm “core-shell” type particles having an optimised pore size of 160 Å. This provides greater separation efficiencies for these types of biomolecules.
HALO-2 Peptide columns offer many advantages including:-
Leica Biosystems, a global leader in anatomic pathology solutions and workflow automation, and Advanced Cell Diagnostics, Inc. (ACD), a world leader in RNA biomarker analysis for precision medicine, today announced a comprehensive partnership to develop and commercialize tissue-based diagnostic tests based on ACD's RNAscope in situ hybridization (ISH) assays on Leica Biosystems' BOND clinical advanced staining instruments.
The agreement supports Leica Biosystems' development and commercialization of fully automated RNAscope-based companion diagnostic (CDx) tests in partnership with biopharmaceutical companies. The combination of ACD's RNAscope technology with Leica Biosystems' fully automated pathology solutions allows companies and laboratories in clinical markets to integrate the power of new RNA-based biomarker tests into the...
‘This basic research set the grounds for structure-based drug design approaches that could be beneficial for cancer treatments’ Dr. Cyril Dominguez, University of Leicester
A team from the University of Leicester has for the first time published a detailed description of a protein linked to many types of cancer. The lab-based study from the Department of Molecular and Cell Biology now provides an opportunity for scientists to develop drugs to target this protein. Dr Cyril Dominguez who led the work at Leicester said: “My research field is structural biology. The proteins that we have studied, called...
Magritek, a leading provider of compact NMR and MRI instruments, expand the range of their Spinsolve Benchtop NMR spectrometers with the Spinsolve Phosphorus.
Key applications include routine purity assessment and reaction monitoring. Recent years have seen the rapid growth of benchtop analytical techniques with uses in teaching, research and industry. Benchtop NMR instruments bring the advantages of space saving; they do not require special laboratory conditions or advanced, highly trained operators; and they may be operated in environments which may benefit from the simplicity of mounting on a...
The new ZEISS Smartproof 5 widefield confocal microscope is designed for a wide range of industrial applications in quality assurance and quality control departments, production environments and R&D labs. The microscope system provides 3D reconstructions and roughness measurements for a wide range of work piece surfaces. Users benefit from an integrated design, repeatable results and high throughput...
Vivantis is pleased to announce the new ViPrimePLUS Real-time PCR Kits and Master Mixes Series
As part of the continuous efforts in research and development to maintain a constant stream of new innovation, Vivantis is pleased to announce the new ViPrimePLUS Real-time PCR Kits and Master Mixes Series. The aim of Vivantis is to accelerate research productivity and to address the needs of researchers worldwide. Vivantis is able to offer more than 200 kits under the ViPrimePLUS qPCR/RT-qPCR group. All of these kits have been developed with high specific genome detection capability. They are fast and easy to use as well as having high sensitivity....
The Omega Lum G from Aplegen is rapidly growing into the gel and western blot imaging documentation system of choice for many people. Installations are growing across Europe as more and more researchers learn about the high performance and yet low cost for this very popular system.
As with all Aplegen systems it is powered by the intelligent SmartCapture Technology which simplifies imaging to the point where the user just has to pick an application and the image is automatically captured with the optimum exposure. This automatically controlled system even takes care of filter selection and focusing. Within seconds the user will have a high quality publication quality image at the click of a button....
The ideal solution for scaling studies and low volume ultra- and diafiltration operations
Sartorius Stedim Biotech (SSB), an international leading supplier for the biopharmaceutical industry, announces the launch of SARTOFLOW® Smart, the smart and easy benchtop crossflow system for optimized ultra- and diafiltration applications. It can ideally be used in many downstream processes, such as purification of vaccines, monoclonal antibodies and recombinant proteins. The system is suitable for flexible use in laboratory...
Genevac Series 3 HT evaporators provide an ideal solution for evaporation bottlenecks in high throughput medicinal chemistry, natural product and production laboratories that generate large numbers of samples for processing.
Compact in design and offering a very high capacity for a wide range of sample formats including microplates, vials, and fraction collection tubes, Series 3 HT evaporators offer the versatility and productivity to assist chemists tasked with drying large numbers of samples. The high-throughput design of a Series 3 HT evaporator allows up to 48 shallow-well microplates to be dried down at the same time, while capacity for standard 16 x 100mm fraction collector tubes is...
Prior Scientific reports that its OptiScan® controller together with associated microscope stage and focus motor have been used to create stunning artistic designs.
Using this equipment, Richard Weston, a former Professor of Architecture at Cardiff University (UK) has acquired high magnification images of minerals, such as agate, fluorite, and calcite, to produce unique designs for a range of products including scarves, glass panels, and in one case a facade for a three story house. Asked about his novel use of the Prior stage and stepper motor, Richard Weston commented...
The ease of configuration offered within Matrix Gemini LIMS (Laboratory Information Management System) will be showcased at PITTCON by Autoscribe Informatics.
Visitors to Booth #4063 can see a sample registration/submission screen tailored to their exact requirements. Visitors simply need to stop by Booth #4063 with a sketch of how they would like the screen to look and let Autoscribe Informatics staff configure it before their very eyes! This real-life demonstration highlights how easy it is to modify any workflow, screen or report to the exact needs of any laboratory and see the...
Themis Bioscience GmbH, a leading company developing prophylactic vaccines against emerging tropical infectious diseases, today announced the appointment of two new leadership members, Dr. Philippe Dro and Dr. Christian Mandl.
The appointment follows in the wake of the successful completion of a phase I clinical trial of the company's Chikungunya vaccine, and so Themis is heading for hot times – and is growing steadily. Dr. Philippe Dro, a renowned life science entrepreneur will join the Board of Directors. The Scientific Advisory Board of Themis Bioscience will in the future benefit from the outstanding experience of Dr. Christian Mandl as chai....
The ideal solution for scaling studies and low volume ultra- and diafiltration operations
Sartorius Stedim Biotech (SSB), an international leading supplier for the biopharmaceutical industry, announces the launch of SARTOFLOW® Smart, the smart and easy benchtop crossflow system for optimized ultra- and diafiltration applications. It can ideally be used in many downstream processes, such as purification of vaccines, monoclonal antibodies and recombinant proteins. The system is suitable for flexible use in laboratory...
Native Chromatin Immunoprecipitation (N-ChIP) is an alternative to traditional cross-linked (X-ChIP), which removes the need for fixing cells with formaldehyde prior to extraction. As a consequence the cells remain in a more natural 'native state'. The DNA/protein fragments are selectively immunoprecipitated using antibodies directed against the protein of interest and the resulting fractions treated to separate the DNA and...
The overarching goal of the Consortium is to identify the key predictors of clinical response and remission in RA patients, and to identify those individuals at high risk of developing Rheumatoid Arthritis (RA). RA is one of the most common auto-immune diseases in the world. RA patients may experience difficulties with everyday tasks and restricted work options. Thus, RA has massive health economic implications. Early intervention...
In this first partnership of its kind in Europe, Myeloma UK and the SGC have explicitly agreed not to file for patents on any of the collaborative research and to make all reagents and knowledge available without restriction to the wider research community, including pharmaceutical, biotech, and academic research groups. 
Anybody working in a laboratory and using pipettes and tips knows how much waste tip racks produce, how expensive they are to dispose of and the amount of space these used racks can take up. For most labs the cost of running a recycling scheme can be prohibatory as they tend to be priced upon the weight of the plastic being recycled.
Since chamber size has a major influence on autoclave selection, Priorclave designed the cylindrical chamber of the Q63 with a taller profile than that found in most ‘cylindrical’ machines, giving these autoclaves an impressive load capacity ideally suited to sterilising larger bulky items as well as enabling small and taller items could be sterilised in a single process.
The Techne TE-10D thermoregulator can be used to heat and circulate liquids from ambient to 120°C and being a thermoregulator they also offer excellent temperature stability of +/-0.01°C at 40°C. The entire range comes with a bright 4 digit LED temperature display and are ideal for routine laboratory applications. Safety features include an automatic cut-out when low liquid levels are reached and a user adjustable over-temperature cut-out....
These HALO-2 Peptide columns are packed with 2 µm “core-shell” type particles having an optimised pore size of 160 Å. This provides greater separation efficiencies for these types of biomolecules.
The agreement supports Leica Biosystems' development and commercialization of fully automated RNAscope-based companion diagnostic (CDx) tests in partnership with biopharmaceutical companies. The combination of ACD's RNAscope technology with Leica Biosystems' fully automated pathology solutions allows companies and laboratories in clinical markets to integrate the power of new RNA-based biomarker tests into the...
A team from the University of Leicester has for the first time published a detailed description of a protein linked to many types of cancer. The lab-based study from the Department of Molecular and Cell Biology now provides an opportunity for scientists to develop drugs to target this protein. Dr Cyril Dominguez who led the work at Leicester said: “My research field is structural biology. The proteins that we have studied, called...
Key applications include routine purity assessment and reaction monitoring. Recent years have seen the rapid growth of benchtop analytical techniques with uses in teaching, research and industry. Benchtop NMR instruments bring the advantages of space saving; they do not require special laboratory conditions or advanced, highly trained operators; and they may be operated in environments which may benefit from the simplicity of mounting on a...
The new ZEISS Smartproof 5 widefield confocal microscope is designed for a wide range of industrial applications in quality assurance and quality control departments, production environments and R&D labs. The microscope system provides 3D reconstructions and roughness measurements for a wide range of work piece surfaces. Users benefit from an integrated design, repeatable results and high throughput...
As with all Aplegen systems it is powered by the intelligent SmartCapture Technology which simplifies imaging to the point where the user just has to pick an application and the image is automatically captured with the optimum exposure. This automatically controlled system even takes care of filter selection and focusing. Within seconds the user will have a high quality publication quality image at the click of a button....
Sartorius Stedim Biotech (SSB), an international leading supplier for the biopharmaceutical industry, announces the launch of SARTOFLOW® Smart, the smart and easy benchtop crossflow system for optimized ultra- and diafiltration applications. It can ideally be used in many downstream processes, such as purification of vaccines, monoclonal antibodies and recombinant proteins. The system is suitable for flexible use in laboratory...
Compact in design and offering a very high capacity for a wide range of sample formats including microplates, vials, and fraction collection tubes, Series 3 HT evaporators offer the versatility and productivity to assist chemists tasked with drying large numbers of samples. The high-throughput design of a Series 3 HT evaporator allows up to 48 shallow-well microplates to be dried down at the same time, while capacity for standard 16 x 100mm fraction collector tubes is...
Using this equipment, Richard Weston, a former Professor of Architecture at Cardiff University (UK) has acquired high magnification images of minerals, such as agate, fluorite, and calcite, to produce unique designs for a range of products including scarves, glass panels, and in one case a facade for a three story house. 
Visitors to Booth #4063 can see a sample registration/submission screen tailored to their exact requirements. Visitors simply need to stop by Booth #4063 with a sketch of how they would like the screen to look and let Autoscribe Informatics staff configure it before their very eyes! This real-life demonstration highlights how easy it is to modify any workflow, screen or report to the exact needs of any laboratory and see the...
The appointment follows in the wake of the successful completion of a phase I clinical trial of the company's Chikungunya vaccine, and so Themis is heading for hot times – and is growing steadily. Dr. Philippe Dro, a renowned life science entrepreneur will join the Board of Directors. The Scientific Advisory Board of Themis Bioscience will in the future benefit from the outstanding experience of Dr. Christian Mandl as chai....
Sartorius Stedim Biotech (SSB), an international leading supplier for the biopharmaceutical industry, announces the launch of SARTOFLOW® Smart, the smart and easy benchtop crossflow system for optimized ultra- and diafiltration applications. It can ideally be used in many downstream processes, such as purification of vaccines, monoclonal antibodies and recombinant proteins. The system is suitable for flexible use in laboratory...