Computer modelling of our very first cells following conception has provided new insights that could lead to new ways of tackling disease through personalised medicine and cell therapy. A scientist at the University of Leicester has created the first computer model that captures the gene networks involved in human gastrulation, the point at which our cells start to develop our tissues and organs, once dubbed ‘the most important time in your life’...
Wheat containing exotic DNA from wild relatives benefits from up to 50 per cent higher yields in hot weather compared with crops lacking these genes. Following a year when temperature records have been smashed, research from the Earlham Institute in Norwich, in collaboration with the International Maize and Wheat Improvement Centre (CIMMYT), offers much-needed hope for improving crop resilience and food security in the face of climate change...
Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, has announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases. Overseen by structural biology experts Professor Helen Walden, UoG, and Dr Mehmet Gundogdu, Principal Scientist at Ubiquigent...
Waters Corporation (NYSE:WAT) has announced it has entered into an agreement to acquire Wyatt Technology, a pioneer in innovative light scattering and field-flow fractionation instruments, software, accessories, and services, for $1.36 billion in cash, subject to certain adjustments. The transaction is expected to close in the second quarter of 2023, subject to regulatory approvals and other customary closing conditions...
PEAK Scientific Instruments has been awarded a new Seal of Quality award, in recognition of outstanding feedback received from scientists globally. The Genius NM32LA Nitrogen Generator, with over 80 reviews and an average star rating of 4.7 out of 5, has earned a Silver Seal of Quality award. Seals of Quality recognize the top 0.1% of products that consistently get the highest customer review ratings on leading independent laboratory technology website...
Visitors to the Autoscribe Informatics booth will see the key developments introduced to our flagship Matrix Gemini LIMS since the last PITTCON. The world’s most configurable Laboratory Information Management System (LIMS) has been further enhanced with a completely new web-based user interface. Other significant changes include improved test creation and editing capabilities that reduce the time to set up or modify tests...
Top 5 Questions to fnd the Perfect Preparative HPLC System for your Purification needs. There are many variables to consider when configuring an HPLC system. To help, here are the top five questions you need to answer. Sample Injection, do you need manual or automated sample injection?. Pumping System, what size of column do you need? Detection, what type of detector do you require? Top tips from Gilson...
Thermo Fisher Scientific, the world leader in serving science, and Celltrio, a leading manufacturer of robotics-based solutions for the life sciences industry, have announced their collaboration to bring a fully automated cell culture system to biotherapeutics customers. The collaboration will integrate the Thermo Scientific Momentum workflow scheduling software with the Celltrio RoboCell cell line automation platform to address the critical unmet market need for high-throughput automated cell line culturing and maintenance...
Eppendorf and the journal Science are now accepting applications for the 2023 Eppendorf & Science Prize for Neurobiology. This annual international research prize of US$25,000 is awarded to young scientists for their outstanding contributions to neurobiological research based on methods of molecular and cell biology. Researchers who are not older than 35 years are invited to apply by June 15, 2023...
TransCure bioServices adds BioVolume 3D imaging to its service offerings, enabling them to deliver even higher quality tumor growth results to customers. With a deeper understanding of how tumors grow and respond to stimuli, researchers can more quickly develop the highly efficacious treatments urgently needed to tackle different cancers. The new service is a world first in 3D imaging, allowing the measurement and visualization of tumor growth in animal models across preclinical research, oncology, and drug development.
As part of a global, multiyear agreement, Thermo Fisher Scientific has announced it is working with AstraZeneca to develop a solid tissue and blood-based companion diagnostic (CDx) test for Tagrisso (osimertinib). The CDx will help identify patients with non-small cell lung cancer (NSCLC) who may be eligible for treatment with Tagrisso by identifying tumors that exhibit epidermal growth factor receptor (EGFR) alterations including exon 21 L858R mutations, exon 19 deletions or T790M mutations...
Dolomite Bio launches new website, with exciting re brand with a new name and focus. The motivation behind the company’s name change to Do Bio reflects their evolution within the microfluidic, biology and life science space. The expertise behind Do Bio’s technology is built on a strong foundation in the field of microfluidics. As the company has grown in recent years, the focus has shifted from purely single cell based applications, to developing and supporting multiple microfluidics based products for life sciences and pharmaceuticals...
Blood samples and urine tests? MRNA or cancer research? Microbe detection in drinking water or PCR tests? Many young women in the UK have virtually no idea what it would be like to work in a laboratory profession as revealed in a survey by laboratory product manufacturer Starlab International. The lack of knowledge of career profiles in science has a severe impact on skills shortage and on many women’s choice of a profession and career opportunities...
Scientists at Microsynth – a leading European company in nucleic acid synthesis, analysis and sequencing – are taking advantage of the remarkable liquid handling capabilities of INTEGRA’s MINI 96 and VIAFLO 96 handheld electronic pipettes in workflows ranging from nucleic acid isolation to sequencing and different types of PCR. Dr Sergey Yakushev, Head of Genetic Analysis at Microsynth, explained...
Novel method of image analysis reveals how cancer cells manipulate their size to resist treatment. Cancer cells can shrink or super-size themselves to survive drug treatment or other challenges within their environment, researchers have discovered. Scientists at The Institute of Cancer Research, London, combined biochemical profiling technologies with mathematical analyses to reveal how genetic changes lead to differences in the size of cancer cells – and how these changes could be exploited by new treatments...
Computational chemistry, a branch of chemistry that applies computer simulation to assist in solving chemical problems, is a heated topic in the modern scientific community. Possessing a powerful team of experts in chemistry, biology, mathematics, crystallography, and pharmacology, Alfa Chemistry focuses on combining the power of computational chemistry with a variety of research focuses on supporting Computer Aided Drug Design...
Agilent Technologies has announced it is investing approximately $725 million to double manufacturing capacity of therapeutic nucleic acids in response to rapid growth of the $1 billion market and strong demand for the company’s high-quality active pharmaceutical ingredients (API).Therapeutic nucleic acids, also called therapeutic oligonucleotides or oligos, are short DNA and RNA molecules that serve as the API for drugs targeting a growing number of diseases...
Azenta, Inc. has announced that it has acquired Ziath, Ltd. and its subsidiaries ("Ziath"). Based in Cambridge, UK, Ziath is a leading provider of 2D barcode readers for life sciences applications. Founded in 2005, Ziath's innovative 2D barcode readers are a key component of the laboratory automation workflow serving pharmaceutical, biotech and academic customers worldwide...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2023 LIMS Webcast series on Wednesday, February 15, with See How LIMS is Making a Splash in the Water/Wastewater Industry. This webcast will provide an update on some of the leading challenges water, wastewater, and environmental laboratories are facing today and focus on the ways in which some of the latest advances in laboratory automation and LIMS are addressing these challenges...
Chemists from the Chianese Group at Colgate University (NY, USA) have shared kinetic data obtained using the Asynt Multicell 10-position high pressure laboratory reactor in their recent paper, “The Key Role of the Latent N0H Group in Milstein’s Catalyst for Ester Hydrogenation”. Their characterisation of the mechanisms of Milstein’s catalysts has enabled greater understanding of the reactivity of these catalysts in ester hydrogenation...
Analytik Jena's thermal cyclers are known for their high-performance and excellent temperature management. To make them even easier and more convenient to operate and monitor, the company has launched new thermal cycler management software. Efficiency pressure and documentation obligations – the challenges in everyday life science laboratories continue to increase. With its new thermal cycler software "Biometra TSuite", Analytik Jena is addressing precisely this issue...
Cherwell, specialists in cleanroom microbiology solutions for the pharmaceutical, healthcare and related industries, has published an update to its guide on “Environmental Monitoring Processes and Validation”, incorporating specific detail on the new version of EU GMP Annex 1. This aims to help sterile medicinal product manufacturers with reviewing and improving their Environmental Monitoring (EM) programs in preparation for compliance with the revised guidelines by August 2023...
Computer modelling of our very first cells following conception has provided new insights that could lead to new ways of tackling disease through personalised medicine and cell therapy. A scientist at the University of Leicester has created the first computer model that captures the gene networks involved in human gastrulation, the point at which our cells start to develop our tissues and organs, once dubbed ‘the most important time in your life’...
Wheat containing exotic DNA from wild relatives benefits from up to 50 per cent higher yields in hot weather compared with crops lacking these genes. Following a year when temperature records have been smashed, research from the Earlham Institute in Norwich, in collaboration with the International Maize and Wheat Improvement Centre (CIMMYT), offers much-needed hope for improving crop resilience and food security in the face of climate change...
Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, has announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases. Overseen by structural biology experts Professor Helen Walden, UoG, and Dr Mehmet Gundogdu, Principal Scientist at Ubiquigent...
Waters Corporation (NYSE:WAT) has announced it has entered into an agreement to acquire Wyatt Technology, a pioneer in innovative light scattering and field-flow fractionation instruments, software, accessories, and services, for $1.36 billion in cash, subject to certain adjustments. The transaction is expected to close in the second quarter of 2023, subject to regulatory approvals and other customary closing conditions...
PEAK Scientific Instruments has been awarded a new Seal of Quality award, in recognition of outstanding feedback received from scientists globally. The Genius NM32LA Nitrogen Generator, with over 80 reviews and an average star rating of 4.7 out of 5, has earned a Silver Seal of Quality award. Seals of Quality recognize the top 0.1% of products that consistently get the highest customer review ratings on leading independent laboratory technology website...
Visitors to the Autoscribe Informatics booth will see the key developments introduced to our flagship Matrix Gemini LIMS since the last PITTCON. The world’s most configurable Laboratory Information Management System (LIMS) has been further enhanced with a completely new web-based user interface. Other significant changes include improved test creation and editing capabilities that reduce the time to set up or modify tests...
Top 5 Questions to fnd the Perfect Preparative HPLC System for your Purification needs. There are many variables to consider when configuring an HPLC system. To help, here are the top five questions you need to answer. Sample Injection, do you need manual or automated sample injection?. Pumping System, what size of column do you need? Detection, what type of detector do you require? Top tips from Gilson...
Thermo Fisher Scientific, the world leader in serving science, and Celltrio, a leading manufacturer of robotics-based solutions for the life sciences industry, have announced their collaboration to bring a fully automated cell culture system to biotherapeutics customers. The collaboration will integrate the Thermo Scientific Momentum workflow scheduling software with the Celltrio RoboCell cell line automation platform to address the critical unmet market need for high-throughput automated cell line culturing and maintenance...
Eppendorf and the journal Science are now accepting applications for the 2023 Eppendorf & Science Prize for Neurobiology. This annual international research prize of US$25,000 is awarded to young scientists for their outstanding contributions to neurobiological research based on methods of molecular and cell biology. Researchers who are not older than 35 years are invited to apply by June 15, 2023...
TransCure bioServices adds BioVolume 3D imaging to its service offerings, enabling them to deliver even higher quality tumor growth results to customers. With a deeper understanding of how tumors grow and respond to stimuli, researchers can more quickly develop the highly efficacious treatments urgently needed to tackle different cancers. The new service is a world first in 3D imaging, allowing the measurement and visualization of tumor growth in animal models across preclinical research, oncology, and drug development.
As part of a global, multiyear agreement, Thermo Fisher Scientific has announced it is working with AstraZeneca to develop a solid tissue and blood-based companion diagnostic (CDx) test for Tagrisso (osimertinib). The CDx will help identify patients with non-small cell lung cancer (NSCLC) who may be eligible for treatment with Tagrisso by identifying tumors that exhibit epidermal growth factor receptor (EGFR) alterations including exon 21 L858R mutations, exon 19 deletions or T790M mutations...
Dolomite Bio launches new website, with exciting re brand with a new name and focus. The motivation behind the company’s name change to Do Bio reflects their evolution within the microfluidic, biology and life science space. The expertise behind Do Bio’s technology is built on a strong foundation in the field of microfluidics. As the company has grown in recent years, the focus has shifted from purely single cell based applications, to developing and supporting multiple microfluidics based products for life sciences and pharmaceuticals...
Blood samples and urine tests? MRNA or cancer research? Microbe detection in drinking water or PCR tests? Many young women in the UK have virtually no idea what it would be like to work in a laboratory profession as revealed in a survey by laboratory product manufacturer Starlab International. The lack of knowledge of career profiles in science has a severe impact on skills shortage and on many women’s choice of a profession and career opportunities...
Scientists at Microsynth – a leading European company in nucleic acid synthesis, analysis and sequencing – are taking advantage of the remarkable liquid handling capabilities of INTEGRA’s MINI 96 and VIAFLO 96 handheld electronic pipettes in workflows ranging from nucleic acid isolation to sequencing and different types of PCR. Dr Sergey Yakushev, Head of Genetic Analysis at Microsynth, explained...
Novel method of image analysis reveals how cancer cells manipulate their size to resist treatment. Cancer cells can shrink or super-size themselves to survive drug treatment or other challenges within their environment, researchers have discovered. Scientists at The Institute of Cancer Research, London, combined biochemical profiling technologies with mathematical analyses to reveal how genetic changes lead to differences in the size of cancer cells – and how these changes could be exploited by new treatments...
Computational chemistry, a branch of chemistry that applies computer simulation to assist in solving chemical problems, is a heated topic in the modern scientific community. Possessing a powerful team of experts in chemistry, biology, mathematics, crystallography, and pharmacology, Alfa Chemistry focuses on combining the power of computational chemistry with a variety of research focuses on supporting Computer Aided Drug Design...
Agilent Technologies has announced it is investing approximately $725 million to double manufacturing capacity of therapeutic nucleic acids in response to rapid growth of the $1 billion market and strong demand for the company’s high-quality active pharmaceutical ingredients (API).Therapeutic nucleic acids, also called therapeutic oligonucleotides or oligos, are short DNA and RNA molecules that serve as the API for drugs targeting a growing number of diseases...
Azenta, Inc. has announced that it has acquired Ziath, Ltd. and its subsidiaries ("Ziath"). Based in Cambridge, UK, Ziath is a leading provider of 2D barcode readers for life sciences applications. Founded in 2005, Ziath's innovative 2D barcode readers are a key component of the laboratory automation workflow serving pharmaceutical, biotech and academic customers worldwide...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2023 LIMS Webcast series on Wednesday, February 15, with See How LIMS is Making a Splash in the Water/Wastewater Industry. This webcast will provide an update on some of the leading challenges water, wastewater, and environmental laboratories are facing today and focus on the ways in which some of the latest advances in laboratory automation and LIMS are addressing these challenges...
Chemists from the Chianese Group at Colgate University (NY, USA) have shared kinetic data obtained using the Asynt Multicell 10-position high pressure laboratory reactor in their recent paper, “The Key Role of the Latent N0H Group in Milstein’s Catalyst for Ester Hydrogenation”. Their characterisation of the mechanisms of Milstein’s catalysts has enabled greater understanding of the reactivity of these catalysts in ester hydrogenation...
Analytik Jena's thermal cyclers are known for their high-performance and excellent temperature management. To make them even easier and more convenient to operate and monitor, the company has launched new thermal cycler management software. Efficiency pressure and documentation obligations – the challenges in everyday life science laboratories continue to increase. With its new thermal cycler software "Biometra TSuite", Analytik Jena is addressing precisely this issue...
Cherwell, specialists in cleanroom microbiology solutions for the pharmaceutical, healthcare and related industries, has published an update to its guide on “Environmental Monitoring Processes and Validation”, incorporating specific detail on the new version of EU GMP Annex 1. This aims to help sterile medicinal product manufacturers with reviewing and improving their Environmental Monitoring (EM) programs in preparation for compliance with the revised guidelines by August 2023...