Cambio now supplies UK life scientists with the new Globin-Zero™ Gold Kit from Epicentre. This innovative product is used to clean up excess globin mRNA and rRNA in total blood RNA samples, allowing improved identification and sequencing of the target RNA components
Globin-Zero™ Gold Kits efficiently remove abundant globin RNAs from both intact and degraded human, mouse and rat total blood RNA samples. In these samples, as much as 70% of the mRNA can be globin mRNA, and this would account for a large majority of sequencing reads in RNA-Seq experiments. By removing excess RNA, the Globin-Zero™ Gold Kit enables deeper sequencing into blood RNA samples and improved identification of less abundant RNA types, including viral RNA. Complete in just 90 minutes, the rapid, single-pass process saves time and reduces sample waste compared to common multi-step procedures, which require the use of various kits to complete the same task....
Materials and biophysical characterization company Malvern Instruments Ltd and NETZSCH Grinding & Dispersing a worldwide manufacturer of industrial wet and dry grinding, mixing, dispersing and kneading equipment, have entered into a cooperative marketing agreement.
Both organizations serve a broad range of market sectors from pharmaceuticals, ceramics, nano-technology applications, food and surface coatings through to mining metals and minerals. The global agreement, initially in place for three years, will harness the strength of each company’s world-leading brands and unique expertise in materials processing and materials characterization. Under the terms of the agreement NETZSCH will standardize on Malvern’s particle sizing and characterization equipment, primarily the Mastersizer 3000 laser diffraction particle size analyzer...
A new informative booklet entitled ‘Short Guide to 3D Cell Culture’ has been produced by AMSBIO
Drawing upon a wealth of experience of working with a wide range of 3D cell culture procedures and formats the guide is aimed at assisting research scientists looking to culture cells in more physiologically relevant environments. Traditional monolayer cell culture on plastic dishes or in flasks, rarely recreates the conditions cells experience in vivo. Over the past 20 years, many researchers have actively sought ways to culture cells in 3D...
Read MoreCreative Biogene has Announced Stable Cell Line Generation ServiceApr 25, 2013
Creative Biogene has announced a rapid and cost-effective stable cell line service for cellular function assays, trafficking, protein production, target validation, and other research purposes using an innovative and unique platform that allows one to go from gene to stable cell line
The service includes commercial and research cell line based on its proprietary expression vector, for example, ″Lenti-Stable″ (stable cell line using lentivector) and ″Select-Stable″ (stable cell line using selection system) , high throughput cell screening technologies and serum, animal components free process without any adaptation issue in a significantly reduced timeline....
Read MoreMicrosaic Systems Signs Commercial Agreement for Novel Miniaturised Chip-based Scientific InstrumentApr 25, 2013
Microsaic Systems plc (AIM: MSYS), the high technology company developing next generation mass spectrometry instruments, is pleased to announce the signing of a second major agreement to provide its miniature mass spectrometer - the Microsaic 4000 MiD® - as an Original Equipment Manufacturer (OEM).
The agreement is for the global, non-exclusive marketing and sale of the 4000 MiD® as a stand-alone instrument for use in specified applications. The terms of the agreement include commitments to minimum quantities during an initial period of 42 months. Shipments under the agreement are anticipated to commence in Q3 2013....
SELECTBIO is delighted to announce that the European Lab Automation (ELA) 2013 Conference and Tradeshow will open its doors from 6 June
A two day, five conference track congress, the event offers over 75 presentations on automation and its application within life science, alongside an exhibition from leading equipments vendors and supporting companies. ELA provides life science researchers and professionals with an unparalleled opportunity to encourage technological discussions and scientific collaboration....
Biopharma Process Systems (BPS) is pleased to be representing Avestin Liposome Extruders and High Pressure Homogenisers within the UK and Ireland
Avestin is the leading manufacturer of high pressure homogenizers suitable for high-pressure applications such as pharmaceuticals and biotechnology. Founded in 1991, Avestin’s focus on quality of engineering and design led to the development of a unique design that eliminates all o-rings and gaskets in the product path. This means less risk of contamination, easier cleaning and no risk of leakage. All face seals are precision-machined metal-to-metal or metal-to-ceramic for optimal durability and efficiency....
Read MoreNovasep discovers explosive properties of Togni reagent IIApr 23, 2013
Novasep reclassifies reagent and informs market about new safety measures required
Novasep, a leading supplier of purification and global manufacturing solutions of synthetic molecules and biomolecules, today announces its R&D team has discovered and characterised the explosive properties of the Togni reagent II and intermediates at the Novasep Leverkusen site in Germany. The findings have been published in the March edition of the journal Organic Process Research and Development....
Read MoreApr 22, 2013
A two day symposium focussing on today’s challenges to Separation Science posed by Complex Matrices to be held at the Bat Research Labs on 22nd & 23rd May 2013
Chromatographic and mass spectrometric analysis in vegetable matter, smoke aerosols, particulates and products of combustion will be explored by specialists from a variety of industries. An exhibition of analytical instrumentation by leading manufacturers will also form an important element of the symposium....
Metrohm and FOSS have entered into a strategic alliance strengthening the two companies’ leading positions in their respective markets
In this alliance, we, Metrohm, will become the sole global distributor of FOSS NIR instruments for the chemical, petrochemical, pharmaceutical, and environmental sectors. In a nutshell, FOSS NIRSystems will become Metrohm NIRSystems. Metrohm has been known for top-quality solutions for wet chemical analysis for more than 60 years. Now, we are taking a step beyond, bringing to you the finest solutions for NIR Spectroscopy. Our enlarged portfolio gives you even more options to choose and find the perfect solution for your analytical requirements...
Analytik Jena AG, based in Jena, Germany has acquired all of the outstanding shares of Upland, California based UVP, LLC including its subsidiary, Ultra-Violet Products, Ltd., located in Cambridge UK.
UVP is a leading manufacturer of bioimaging systems for applications in proteomics, genomics, plant and animal sciences. The company also manufactures ultraviolet products, light sources, and laboratory equipment such as hybridization ovens, transilluminators, crosslinkers and PCR hoods....
Curie-Cancer, the body responsible for developing Institut Curie’s industry partnership activities, today announces a strong increase in the number of early stage clinical trials (phase I) from three in 2010 to ten in 2012. The studies are being conducted with industry partners
The rise in the number of studies is a direct result of the changes in strategic direction put in place by professor Pierre Teillac, director of the Institut Curie Hospital Group and the recent launch of the Clinical Research Department, headed by Veronique Dieras, in response to the needs of industry partners...
Read MoreExtended Mass Spec Imaging Services Now AvailableApr 18, 2013
Protea Biosciences, a leading developer of innovative bioanalytical products and services, announced today the release of an extended mass spectrometry imaging (MSI) service offering from the Mass Spec Imaging Center (MSIC™).
This new service portfolio offers advanced MSI services using Protea’s proprietary LAESI DP-1000 Direct Ionization System as well as MALDI (Matrix-Assisted Laser Desorption/Ionization) mass spectrometry for a wide variety of sample types and applications. “This new portfolio of services offers researchers an opportunity to ‘detect’ where their molecules of interest reside in a biological matrix,” said Alessandro Baldi PhD, Protea’s Vice President and General Manager. “This spatial information offers critical insight for researchers working in the fields like metabolomics, biomarker discovery, drug discovery, and histopathology.”....
Wyatt Technology is pleased to report the success of the Calypso® composition-gradient multi-angle light scattering (CG-MALS) system in a study conducting by the Molecular Interactions Research Group (MIRG) of the Association of Biomolecular Research Facilities (ABRF). The conclusions of the 2012 MIRG study were announced at the ABRF 2013 annual meeting in Palm Springs earlier this month.
In the study, a pair of unknown proteins, prepared and characterized by the ABRF, was sent out to multiple labs to determine binding affinity and stoichiometry. In a single afternoon consisting of 2 CG-MALS runs, the Wyatt Calypso system correctly determined that Protein Y (26.3 kDa) contains two binding sites for Protein X (11.9 kDa). The first X binds with KD of 10 nM and the second X binds with 14 μM. This analysis agreed perfectly with extensive analytical ultracentrifugation (AUC) and isothermal titration calorimetry (ITC) measurements performed by ABRF prior to distributing the samples....
Structural Proteomics Laboratory Directed by Prof. Dr. Amit Kumar Mandal Recognized for Global Disease Research
At a ceremony at St. John’s Research Institute (Bangalore, India) Waters announced the selection of the St. John’s Research Institute for its Centers of Innovation Program for research in the field of structural proteomics. It is the first institution in India to receive the designation of a Waters® Center of Innovation. Under the direction of Prof. Dr. Amit Kumar Mandal, a Professor of Molecular Medicine and Clinical Proteomics, St. John’s has earned a reputation for its research in blood disorders and other diseases that disproportionately affect disadvantaged populations...
The German Society for Cell Biology (DGZ) in Heidelberg has recognized outstanding research in the field of basic cell biology this year with the BINDER Innovation Prize with a 4,000 Euro endowment
Among the many scientific papers, the work from Dr. Stephan Grill of the Max Planck Institute for Physics of Complex Systems (MPI-PKS) and Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBF) in Dresden, Germany stood above the rest. The scientist impressed the independent jury with his article on the interaction of mechanical and biochemical signals for the biological process of cell polarization....
Researchers at the University Medical Center (UMC) Utrecht, the Netherlands, have identified a novel gene mutation that predisposes to seminoma, the most common form of testicular cancer in young men
The newly identified mutation, in the LRRC50 gene, can be considered as a new risk factor for testicular cancer and may be useful for screening purposes. The finding was published this week in PLoS Genetics. In preclinical research in zebrafish, it was found that mutation in the LRRC50 gene predisposes to testicular tumor formation and that zebrafish LRRC50 tumors are similar to human seminoma. These unique findings make zebrafish a useful animal model for human seminoma associated with mutation of the LRRC50 gene...
METTLER TOLEDO’s new on-demand webinar, “Methods to Improve Chemical Process Development,” takes on the challenges of today’s pharmaceutical market
The free webinar lays out the pressures currently being faced by the industry—including cost and regulatory pressures—and explores the chemistry workflows and emerging technologies that are helping industry participants address these challenges, remain competitive, and protect profits. With the reality of patent cliffs, regulatory standards, attrition, and globalization, companies are learning to work fast and “lean” without sacrificing effectiveness and safety...
Anasys Instruments continues to expand the capabilities of their nanoscale materials characterization techniques with the Lorentz Contact Resonance (LCR) imaging mode. This is now available for their afm+® and nanoIR™ systems
The Lorentz Contact Resonance imaging mode further enhances the capabilities of the afm+ and nanoIR systems from Anasys. LCR allows rapid broadband nanomechanical measurements over a range of temperatures. LCR imaging differentiates between multiple components of a sample and allows precise location of the probe for subsequent chemical or thermal analysis with nanoscale resolution...
Read MoreNew Eppendorf Advantage promotion delivers up to 20% savingsApr 16, 2013
Valid until 30 June 2013, Eppendorf’s latest Advantage promotion delivers considerable savings on a variety of product bundles, offering researchers the chance to try products from this leading brand for the first time at a lower than usual investment, or to stock up on valued consumables and equipment
Purchasers can make savings of up to 20% on Eppendorf Combitips® advanced/Multipette® bundles, as well as taking advantage of offers on the Eppendorf µCuvette™ G1.0 and BioSpectrometers.Supporting serial pipetting together with the Eppendorf Multipette®, Eppendorf Combitips advanced are available in a range of purity grades to support work across all life science laboratories, whatever the application....
Thermo Fisher Scientific and Life Technologies Corporation, a leading life sciences company, have signed a definitive agreement under which Thermo Fisher will acquire Life Technologies for $76.00 in cash per fully diluted common share, or approximately $13.6 billion, plus the assumption of net debt at close ($2.2 billion as of year end 2012)
The transaction, which was approved by both companies’ boards of directors, will create an unrivaled leader in serving research, specialty diagnostics and applied markets. The combination builds on both companies’ technological strengths to accelerate results for life sciences customers working in proteomics, genomics and cell biology...
Carl Zeiss Microscopy announces that it provided equipment used in the analysis of a meteorite that recently fell in the Chelyabinsk region of Russia
Russian News Agencies said on 18 February that scientists have confirmed the extra-terrestrial origin of dozens of tiny fragments found near Chebarkul Lake. The analysis was performed by the Research-Educational Centre “Nanomaterials and Nanotechnologies" in Urals Federal University. The Ural Federal University (UrFU) is a state-owned university and one of nine in Russia which have the ‘Federal’ status....
Globin-Zero™ Gold Kits efficiently remove abundant globin RNAs from both intact and degraded human, mouse and rat total blood RNA samples. In these samples, as much as 70% of the mRNA can be globin mRNA, and this would account for a large majority of sequencing reads in RNA-Seq experiments. By removing excess RNA, the Globin-Zero™ Gold Kit enables deeper sequencing into blood RNA samples and improved identification of less abundant RNA types, including viral RNA. Complete in just 90 minutes, the rapid, single-pass process saves time and reduces sample waste compared to common multi-step procedures, which require the use of various kits to complete the same task....
Both organizations serve a broad range of market sectors from pharmaceuticals, ceramics, nano-technology applications, food and surface coatings through to mining metals and minerals. The global agreement, initially in place for three years, will harness the strength of each company’s world-leading brands and unique expertise in materials processing and materials characterization. Under the terms of the agreement NETZSCH will standardize on Malvern’s particle sizing and characterization equipment, primarily the Mastersizer 3000 laser diffraction particle size analyzer...
Drawing upon a wealth of experience of working with a wide range of 3D cell culture procedures and formats the guide is aimed at assisting research scientists looking to culture cells in more physiologically relevant environments. Traditional monolayer cell culture on plastic dishes or in flasks, rarely recreates the conditions cells experience in vivo. Over the past 20 years, many researchers have actively sought ways to culture cells in 3D...
The service includes commercial and research cell line based on its proprietary expression vector, for example, ″Lenti-Stable″ (stable cell line using lentivector) and ″Select-Stable″ (stable cell line using selection system) , high throughput cell screening technologies and serum, animal components free process without any adaptation issue in a significantly reduced timeline....
The agreement is for the global, non-exclusive marketing and sale of the 4000 MiD® as a stand-alone instrument for use in specified applications. The terms of the agreement include commitments to minimum quantities during an initial period of 42 months. Shipments under the agreement are anticipated to commence in Q3 2013....
A two day, five conference track congress, the event offers over 75 presentations on automation and its application within life science, alongside an exhibition from leading equipments vendors and supporting companies. ELA provides life science researchers and professionals with an unparalleled opportunity to encourage technological discussions and scientific collaboration....
Avestin is the leading manufacturer of high pressure homogenizers suitable for high-pressure applications such as pharmaceuticals and biotechnology. Founded in 1991, Avestin’s focus on quality of engineering and design led to the development of a unique design that eliminates all o-rings and gaskets in the product path. This means less risk of contamination, easier cleaning and no risk of leakage. All face seals are precision-machined metal-to-metal or metal-to-ceramic for optimal durability and efficiency....
Novasep, a leading supplier of purification and global manufacturing solutions of synthetic molecules and biomolecules, today announces its R&D team has discovered and characterised the explosive properties of the Togni reagent II and intermediates at the Novasep Leverkusen site in Germany. The findings have been published in the March edition of the journal Organic Process Research and Development....
Chromatographic and mass spectrometric analysis in vegetable matter, smoke aerosols, particulates and products of combustion will be explored by specialists from a variety of industries. An exhibition of analytical instrumentation by leading manufacturers will also form an important element of the symposium....
In this alliance, we, Metrohm, will become the sole global distributor of FOSS NIR instruments for the chemical, petrochemical, pharmaceutical, and environmental sectors. In a nutshell, FOSS NIRSystems will become Metrohm NIRSystems. Metrohm has been known for top-quality solutions for wet chemical analysis for more than 60 years. Now, we are taking a step beyond, bringing to you the finest solutions for NIR Spectroscopy. Our enlarged portfolio gives you even more options to choose and find the perfect solution for your analytical requirements...
UVP is a leading manufacturer of bioimaging systems for applications in proteomics, genomics, plant and animal sciences. The company also manufactures ultraviolet products, light sources, and laboratory equipment such as hybridization ovens, transilluminators, crosslinkers and PCR hoods....
The rise in the number of studies is a direct result of the changes in strategic direction put in place by professor Pierre Teillac, director of the Institut Curie Hospital Group and the recent launch of the Clinical Research Department, headed by Veronique Dieras, in response to the needs of industry partners...
This new service portfolio offers advanced MSI services using Protea’s proprietary LAESI DP-1000 Direct Ionization System as well as MALDI (Matrix-Assisted Laser Desorption/Ionization) mass spectrometry for a wide variety of sample types and applications. “This new portfolio of services offers researchers an opportunity to ‘detect’ where their molecules of interest reside in a biological matrix,” said Alessandro Baldi PhD, Protea’s Vice President and General Manager. “This spatial information offers critical insight for researchers working in the fields like metabolomics, biomarker discovery, drug discovery, and histopathology.”....
In the study, a pair of unknown proteins, prepared and characterized by the ABRF, was sent out to multiple labs to determine binding affinity and stoichiometry. In a single afternoon consisting of 2 CG-MALS runs, the Wyatt Calypso system correctly determined that Protein Y (26.3 kDa) contains two binding sites for Protein X (11.9 kDa). The first X binds with KD of 10 nM and the second X binds with 14 μM. This analysis agreed perfectly with extensive analytical ultracentrifugation (AUC) and isothermal titration calorimetry (ITC) measurements performed by ABRF prior to distributing the samples....
At a ceremony at St. John’s Research Institute (Bangalore, India) Waters announced the selection of the St. John’s Research Institute for its Centers of Innovation Program for research in the field of structural proteomics. It is the first institution in India to receive the designation of a Waters® Center of Innovation. Under the direction of Prof. Dr. Amit Kumar Mandal, a Professor of Molecular Medicine and Clinical Proteomics, St. John’s has earned a reputation for its research in blood disorders and other diseases that disproportionately affect disadvantaged populations...
Among the many scientific papers, the work from Dr. Stephan Grill of the Max Planck Institute for Physics of Complex Systems (MPI-PKS) and Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBF) in Dresden, Germany stood above the rest. The scientist impressed the independent jury with his article on the interaction of mechanical and biochemical signals for the biological process of cell polarization....
The newly identified mutation, in the LRRC50 gene, can be considered as a new risk factor for testicular cancer and may be useful for screening purposes. The finding was published this week in PLoS Genetics. In preclinical research in zebrafish, it was found that mutation in the LRRC50 gene predisposes to testicular tumor formation and that zebrafish LRRC50 tumors are similar to human seminoma. These unique findings make zebrafish a useful animal model for human seminoma associated with mutation of the LRRC50 gene...
The free webinar lays out the pressures currently being faced by the industry—including cost and regulatory pressures—and explores the chemistry workflows and emerging technologies that are helping industry participants address these challenges, remain competitive, and protect profits. With the reality of patent cliffs, regulatory standards, attrition, and globalization, companies are learning to work fast and “lean” without sacrificing effectiveness and safety...
The Lorentz Contact Resonance imaging mode further enhances the capabilities of the afm+ and nanoIR systems from Anasys. LCR allows rapid broadband nanomechanical measurements over a range of temperatures. LCR imaging differentiates between multiple components of a sample and allows precise location of the probe for subsequent chemical or thermal analysis with nanoscale resolution...
Purchasers can make savings of up to 20% on Eppendorf Combitips® advanced/Multipette® bundles, as well as taking advantage of offers on the Eppendorf µCuvette™ G1.0 and BioSpectrometers.Supporting serial pipetting together with the Eppendorf Multipette®, Eppendorf Combitips advanced are available in a range of purity grades to support work across all life science laboratories, whatever the application....
The transaction, which was approved by both companies’ boards of directors, will create an unrivaled leader in serving research, specialty diagnostics and applied markets. The combination builds on both companies’ technological strengths to accelerate results for life sciences customers working in proteomics, genomics and cell biology...