Spinout Company secures £850,000 to develop vaccines against infection
A COMPANY working to develop vaccines and antibodies to treat bacterial infections has secured a £850,000 investment. Absynth Biologics Limited, a UK biotechnology spinout company from the University of Sheffield, has secured £400,000 from The North West Fund for Biomedical, managed by SPARK Impact as well as £450,000 from Fusion IP plc, the university commercialisation company. The North West Fund for Biomedical is part of the wider £155m North West Fund, financed jointly by the European Regional Development Fund and the European Investment Bank...
New Eppendorf Tube 5.0 mL system fills the volume gap in sample preparation and storage
When working with samples between 2 and 5 mL, researchers often have no choice but to use tubes that are really designed for larger volumes, typically 15 mL conical screw cap tubes. The new Eppendorf Tube 5.0 mL now provides the ‘missing link’ for such samples, delivering a high-quality solution for volumes up to 5 mL. These new tubes feature a practical and convenient snap cap for single-hand operation and a compact conical design, removing the contamination risks associated with manipulating small volumes in large tubes...
Nanotechnology conference secures new backers for next year’s event
Nano London 2014, a conference and exhibition for the international nanotechnology industry, is heading confidently towards next year’s event after securing further investment and adding to its list of key industry partnerships. The conference will assemble the leading thinkers and players in the nanotechnology field, and serve as a platform for education, communication, collaboration and innovation...
New Cellaxess® Project Grant supports advanced research projects
As a leading provider of advanced cell-based screening technologies and services, Cellectricon is inviting researchers to apply for the recently launched Cellaxess Project Grant. The Grant is open to any scientist or research group wanting to capitalize on the advanced electromanipulation capabilities of the Cellaxess® platform for the cellular delivery of non-genetic material, particularly small molecules and peptides. Winners will be selected from two categories, basic and applied cell-based research, and will receive the Cellaxess ACE platform, along with all consumables and reagents, for a fully supported project...
Children’s Liver Disease Foundation (CLDF) is inviting applications for its 2013/14 research project award.
The charity is making £200,000 available to be applied to medical or social research in line with its research strategy. CLDF is theUK’s leading charity fighting childhood liver disease and has a strong track record in this field, with over £8m of research funding being delivered since 1980. Full details of its research strategy, previous research grants and details of how to apply are available at childliverdisease.org/research...
UK-BASED contract research and manufacturing organisation Molecular Profiles has opened the doors of its new facility following a successful inspection from the Medicines and Healthcare products Regulatory Agency (MHRA).
The Nottingham-based, £9 million pharmaceutical production site will give drug development companies across the world access to the state-of-the-art clinical manufacturing capabilities. Designed to handle a range of non-sterile dosage forms such as solids, liquids, semi-solids and inhaled products, Molecular Profiles’ new 30,000sq ft. facility marks a significant expansion for the company that started life as a spin-out from Nottingham University over 15 years ago...
With the Flexar™ PDA Plus™, the latest addition to the PerkinElmer Flexar liquid chromatography product family, scientists analyzing environmental, food, pharmaceutical and chemical samples can now better meet industry regulations and higher throughput demand.
This innovative technology brings the flexibility of modular design, the power of sensitivity and accuracy and the fastest sampling speeds to the most optically advanced photo diode array (PDA) detector on the market. Its design encompasses the widest detection range of any PDA detector on the market and rivals or exceeds that of conventional UV detectors. Delivering improved 2D and 3D chromatographic information, the PDA detector streamlines analysis with the following features...
It is also common knowledge that pipetting regularly increases the risk of developing Repetitive Strain Injuries. By applying Good Pipetting Practice in your lab you can help to prevent these risks.
One way to help reduce the repetition of pipetting is to simply take frequent breaks every 20 or 30 minutes to stretch your shoulders, arms and hands. Especially if you spend your coffee and lunch breaks texting on your phone – your thumbs will never get a break! To help you with your daily stretches Anachem are offering you this easy & quick routine for your hands, arms, and shoulders. It's been put together by stretching authority Bob Anderson and by combining it with Anachem's Good Pipetting Posture poster...
The new Chromatography Columns and Supplies Catalogue 9 from Hichrom Limited has arrived. With 384 pages of detailed chromatography product information and other useful technical data, this catalogue is an essential tool for every laboratory.
Contained within the catalogue is information on over 100 LC column brands and details of products from over 35 chromatography suppliers. In addition to HPLC, UHPLC and superficially porous particle columns, the new catalogue contains details of SFC, GC, SPE, TLC, Flash, CE, LC-MS and GC-MS products. Vials, syringe filters, tubing, fittings and other chromatography accessories are also included.....
GPE Scientific are pleased to announce the promotion of Hannah Neville and Patrick Delaney onto the Board of Directors.
Hannah Neville has been promoted to Director from her role as Sales and Office Manager. Hannah started working at GPE in 2002 as an Office Junior, over the years Hannah has developed her knowledge of the corporate side of the business as well as an exceptional understanding of the company’s product base. Hannah progressed from Office Junior to an NMR Sales Representative, travelling around the UK and liaising with clients to build relationships and develop lucrative leads for the business.....
Analox Sensor Technologies Ltd, have appointed Presearch as their Partner for the UK. Under the agreement Presearch will be responsible for the Sales and Service for the Analox range of gas sensors in the industrial sector.
Analox manufactures a range of industrial safety equipment for toxic, flammable and inert gases. A number of portable and fixed analysers are available for use in applications such as boiler houses, petrochemical installations, water treatment plants and laboratories.....
Oxford Gene Technology (OGT), provider of innovative genetics research and biomarker solutions to advance molecular medicine, has produced a new, free-to-download application note on combined array comparative genomic hybridisation (aCGH) and single nucleotide polymorphism (SNP) arrays.
The application note, titled ‘Detecting copy number variants and runs of homozygosity on a single array — challenges and applications’ aims to support researchers in navigating this combined approach for the simultaneous detection of copy number variations (CNVs) and runs of homozygosity (ROH). aCGH has established itself as the “gold-standard” platform for array-based CNV detection. Recent advances have enabled the combination of aCGH probes for CNV detection with probes able to detect SNPs...
Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their popular THMS600 stage for polymer research at the Institute of Chemistry and Technology of Polymers (CNR), Italy.
A group of scientists from the CNR is investigating the melting kinetics of poly(3-hydroxybutyrate) (PHB), a natural thermoplastic polymer with mechanical properties comparable to synthetic polymers. PHB is now the focus of scientific interest as it has commercial potential as a fully biodegradable and biocompatible product. Potential uses include environmentally friendly packaging and films, pharmaceutical drug administration, and biocompatible resorbable medical implants. Small batches of PHB have been produced since 1925 by bacterial fermentation, but until now there is no large scale commercial production because it is more expensive than commonly used polymers...
Link Technologies’ solid-supported Cyanine 540 and 650 dyes increase workflow efficiency
Link Technologies Ltd, an ISO 9001:2008 certified specialist oligonucleotide reagent manufacturer, has launched a range of high quality cyanine dye products to support the continued increase in demand for fluorescent labelling in biological imaging and molecular diagnostics. As well as introducing a new range of 3’-CPG solid supports modified with Cyanine 540 and Cyanine 650, Link Technologies now also manufactures and supplies the commonly used phosphoramidites, so researchers can now source an extended range of cyanine reagents produced to Link Technologies’ exacting standards...
Home Office figures reveal massive 8% rise in the use of animals in scientific research
Home Office figures released today showing an 8% rise in the number of procedures conducted using animals in scientific research in 2012 make for ‘immensely distressing and upsetting news’, according to the Dr Hadwen Trust for Humane Research (DHT). In 2012, over 4.1 million procedures were carried out using 4 million animals such as mice, cats, dogs, birds and horses. This is an increase of over 317,000 procedures from 2011...
New website designed as an easy point of reference for Stomacher® applications and protocols
Seward Limited, founding manufacturer and developer of the world leading, patented Stomacher® Laboratory Paddle Blender range, has launched a new, fully refreshed website. This is designed as a readily accessible point of reference for customers seeking assistance in sample preparation for microbiological analysis in the food, life science and environmental sectors. New to the Seward website includes a Resource Centre to help visitors identify how the Stomacher® may be used. In addition, user guides and technical data are available for download, with useful videos demonstrating various routine protocols...
Merck Millipore, the Life Science division of Merck, and Plasticell of London, UK, today announced the availability of OsteoMAX-XF™, the first fully defined, xeno-free human mesenchymal stem cell differentiation medium for the differentiation of mesenchymal stem cells into osteocytes.
Enables rapid differentiation of fully functional human bone tissue from MSCs. More consistent and potent than currently available formulations. Accelerates time to mineralization to less than one week compared to the typical three weeks. Mineralization can be detected in less than one week, whereas competing products that contain serum require approximately 21 days to produce similar levels of bone formation...
Read More Olink Bioscience Introduces Scalable Protein Biomarker Assays with Proseek MultiplexJul 25, 2013
Molecular tools specialist Olink today launched Proseek® Multiplex - a new generation of multiplexed protein biomarker immunoassays based on its proprietary Proximity Extension Assay (PEA) platform.
Until now, it has been impossible to scale up conventional assays due to increased antibody cross-reactivity when large numbers of assays are run simultaneously. Now with the introduction of Proseek Multiplex, biomarker researchers can quantify 92 proteins in just one microliter sample without compromising data quality orperformance. "We are very proud at Olink to introduce a new and scalable era in immunoassays. Proseek has harnessed the tools that have fueled genomics for many years and put them to use in protein biomarker research. In a few years, we aim to offer the market’s most comprehensive portfolio of protein biomarker assays." says Simon Fredriksson, CEO of Olink Bioscience...
‘Free Range’ Listeria processed by Stomacher 400 Circulator
Seward Limited,manufacturer and developer of the world leading, patented Stomacher® Laboratory Paddle Blender range, has announced that its Stomacher 400 Circulator has been used in a recent study1 to evaluate environmental contamination by Listeria species. The increased interest in animal welfare and free range methods, such as pasture reared poultry, has made it important that there is a greater understanding of the ecology and epidemiology of Listeria in these systems...
A novel solution for analyzing 3D cell cultures, based on Tecan’s Infinite® M200 PRO and InSphero’s 3D InSight™ microtissue technology, is helping to reduce the cost of early phase drug development.
Dr Jens M Kelm, Co-founder and Chief Scientific Officer of InSphero, explained: “Although classical 2D cell culture techniques are still widely used throughout the pharmaceutical industry, their limitations are becoming increasingly apparent. The efficacy of a candidate drug depends on a number of factors, including the physical and chemical environments in vivo, drug penetration and clearance rates. 2D cell cultures do not accurately reflect how all of these factors will affect drug behavior in vivo; 3D cell culturing techniques offer greater biological relevance for drug screening...
Nanounity announces the public launch of new characterization tools and techniques for the microscopy community. Products from Pemtron & Delmic will debut at the annual 2013 Microscopy & Microanalysis Conference & Exhibition to be held in Indianapolis, August 4-8. The company will be presenting exciting new products of manufacturers from the USA, Korea and Europe.
New instrumentation, tools and techniques, will be featured on the Nanounity booth, #828, at this year's annual M&M meeting being held in Indianapolis, August 4-8, 2013. The Pemtron SEMART™ PS-250 scanning electron microscope (SEM) will be making its Nanounity US debut. This intermediate microscope provides users with quick and easy operation offering high performance at a reasonable price, a level that a user might expect to pay at least twice to own. With the power of the PS-230, the PS250 allows users to work with larger samples up to 140 mm while retaining 3 nm spatial resolution. Users may add optional EBSD (Electron Detector Back Scattered) and EDS (Energy Dispersive Spectrometer) for more comprehensive analytical performance...
BBI Solutions, a world leader in immunoassay development and contract manufacturing, will launch its unique range of Recombinant Fab Monoclonal Antibodies on booth #3363 at the American Association for Clinical Chemistry’s (AACC) Annual Meeting and Clinical Lab Expo, on July 28-August 31, 2013, in Houston, Texas.
These matched antibodies pairs, developed using proprietary phage display selection and the Luminex platform, exhibit sub-nanomolar affinities, exceptional sensitivity, and provide assay developers with clinically relevant performance characteristics to 34 biomarkers, with more in development...
A COMPANY working to develop vaccines and antibodies to treat bacterial infections has secured a £850,000 investment. Absynth Biologics Limited, a UK biotechnology spinout company from the University of Sheffield, has secured £400,000 from The North West Fund for Biomedical, managed by SPARK Impact as well as £450,000 from Fusion IP plc, the university commercialisation company. The North West Fund for Biomedical is part of the wider £155m North West Fund, financed jointly by the European Regional Development Fund and the European Investment Bank...
Nano London 2014, a conference and exhibition for the international nanotechnology industry, is heading confidently towards next year’s event after securing further investment and adding to its list of key industry partnerships. The conference will assemble the leading thinkers and players in the nanotechnology field, and serve as a platform for education, communication, collaboration and innovation...
As a leading provider of advanced cell-based screening technologies and services, Cellectricon is inviting researchers to apply for the recently launched Cellaxess Project Grant. The Grant is open to any scientist or research group wanting to capitalize on the advanced electromanipulation capabilities of the Cellaxess® platform for the cellular delivery of non-genetic material, particularly small molecules and peptides. Winners will be selected from two categories, basic and applied cell-based research, and will receive the Cellaxess ACE platform, along with all consumables and reagents, for a fully supported project...
The charity is making £200,000 available to be applied to medical or social research in line with its research strategy. CLDF is theUK’s leading charity fighting childhood liver disease and has a strong track record in this field, with over £8m of research funding being delivered since 1980. Full details of its research strategy, previous research grants and details of how to apply are available at childliverdisease.org/research...
One way to help reduce the repetition of pipetting is to simply take frequent breaks every 20 or 30 minutes to stretch your shoulders, arms and hands. Especially if you spend your coffee and lunch breaks texting on your phone – your thumbs will never get a break! To help you with your daily stretches Anachem are offering you this easy & quick routine for your hands, arms, and shoulders. It's been put together by stretching authority Bob Anderson and by combining it with Anachem's Good Pipetting Posture poster...
Contained within the catalogue is information on over 100 LC column brands and details of products from over 35 chromatography suppliers. In addition to HPLC, UHPLC and superficially porous particle columns, the new catalogue contains details of SFC, GC, SPE, TLC, Flash, CE, LC-MS and GC-MS products. Vials, syringe filters, tubing, fittings and other chromatography accessories are also included.....
Hannah Neville has been promoted to Director from her role as Sales and Office Manager. Hannah started working at GPE in 2002 as an Office Junior, over the years Hannah has developed her knowledge of the corporate side of the business as well as an exceptional understanding of the company’s product base. Hannah progressed from Office Junior to an NMR Sales Representative, travelling around the UK and liaising with clients to build relationships and develop lucrative leads for the business.....
A group of scientists from the CNR is investigating the melting kinetics of poly(3-hydroxybutyrate) (PHB), a natural thermoplastic polymer with mechanical properties comparable to synthetic polymers. PHB is now the focus of scientific interest as it has commercial potential as a fully biodegradable and biocompatible product. Potential uses include environmentally friendly packaging and films, pharmaceutical drug administration, and biocompatible resorbable medical implants. Small batches of PHB have been produced since 1925 by bacterial fermentation, but until now there is no large scale commercial production because it is more expensive than commonly used polymers...
Link Technologies Ltd, an ISO 9001:2008 certified specialist oligonucleotide reagent manufacturer, has launched a range of high quality cyanine dye products to support the continued increase in demand for fluorescent labelling in biological imaging and molecular diagnostics. As well as introducing a new range of 3’-CPG solid supports modified with Cyanine 540 and Cyanine 650, Link Technologies now also manufactures and supplies the commonly used phosphoramidites, so researchers can now source an extended range of cyanine reagents produced to Link Technologies’ exacting standards...
Home Office figures released today showing an 8% rise in the number of procedures conducted using animals in scientific research in 2012 make for ‘immensely distressing and upsetting news’, according to the Dr Hadwen Trust for Humane Research (DHT). In 2012, over 4.1 million procedures were carried out using 4 million animals such as mice, cats, dogs, birds and horses. This is an increase of over 317,000 procedures from 2011...
Seward Limited, founding manufacturer and developer of the world leading, patented Stomacher® Laboratory Paddle Blender range, has launched a new, fully refreshed website. This is designed as a readily accessible point of reference for customers seeking assistance in sample preparation for microbiological analysis in the food, life science and environmental sectors. New to the Seward website includes a Resource Centre to help visitors identify how the Stomacher® may be used. In addition, user guides and technical data are available for download, with useful videos demonstrating various routine protocols...
Enables rapid differentiation of fully functional human bone tissue from MSCs. More consistent and potent than currently available formulations. Accelerates time to mineralization to less than one week compared to the typical three weeks. Mineralization can be detected in less than one week, whereas competing products that contain serum require approximately 21 days to produce similar levels of bone formation...
Until now, it has been impossible to scale up conventional assays due to increased antibody cross-reactivity when large numbers of assays are run simultaneously. Now with the introduction of Proseek Multiplex, biomarker researchers can quantify 92 proteins in just one microliter sample without compromising data quality orperformance. "We are very proud at Olink to introduce a new and scalable era in immunoassays. Proseek has harnessed the tools that have fueled genomics for many years and put them to use in protein biomarker research. In a few years, we aim to offer the market’s most comprehensive portfolio of protein biomarker assays." says Simon Fredriksson, CEO of Olink Bioscience...
Dr Jens M Kelm, Co-founder and Chief Scientific Officer of InSphero, explained: “Although classical 2D cell culture techniques are still widely used throughout the pharmaceutical industry, their limitations are becoming increasingly apparent. The efficacy of a candidate drug depends on a number of factors, including the physical and chemical environments in vivo, drug penetration and clearance rates. 2D cell cultures do not accurately reflect how all of these factors will affect drug behavior in vivo; 3D cell culturing techniques offer greater biological relevance for drug screening...
New instrumentation, tools and techniques, will be featured on the Nanounity booth, #828, at this year's annual M&M meeting being held in Indianapolis, August 4-8, 2013. The Pemtron SEMART™ PS-250 scanning electron microscope (SEM) will be making its Nanounity US debut. This intermediate microscope provides users with quick and easy operation offering high performance at a reasonable price, a level that a user might expect to pay at least twice to own. With the power of the PS-230, the PS250 allows users to work with larger samples up to 140 mm while retaining 3 nm spatial resolution. Users may add optional EBSD (Electron Detector Back Scattered) and EDS (Energy Dispersive Spectrometer) for more comprehensive analytical performance...
These matched antibodies pairs, developed using proprietary phage display selection and the Luminex platform, exhibit sub-nanomolar affinities, exceptional sensitivity, and provide assay developers with clinically relevant performance characteristics to 34 biomarkers, with more in development...