Multiple myeloma (MM), a proliferation (growth) of malignant plasma cells in the bone marrow destroying bones, accounts for 10% of all hematologic malignancies.
Approximately 45.000 new cases are diagnosed each year together in the US and Europe. MM is mainly a disease of elderly people with age at diagnosis between 65-70 years. During the meeting, recently developed approaches for diagnosis and monitoring will be presented. Gene-expression-profiling to detect molecular subgroups with a different prognosis and high-throughput-sequencing to identify new genetic lesions will be discussed...
INTEGRA has published a new video testimonial* in which researchers at the Institute for Clinical Chemistry at the Technical University of Munich (TUM) describe the benefits of using the VACUSAFE Laboratory Aspiration System to provide simple, reliable and safe aspiration of cell culture supernatents.
The Technische Universität München, or Technical University of Munich (TUM), is a research university with campuses in Munich, Garching and Freising-Weihensstephan, Germany. The TUM is one of the most research-focused universities in Europe and has been ranked 11th in the Academic Ranking of World Universities 2014. The TUM features a strong, characteristic profile in the fields of Science and Engineering...
HORIBA UK Ltd, Medical Division, announces that Coventry University’s Department of Biomolecular and Sports Science has recently installed new HORIBA haematology and clinical chemistry analysers to enhance the future employability of its students.
In recognition of NHS requirements, Coventry can now offer its Biomedical Science degree students practical experience of real-life clinical instrumentation and applications. Consequently, this enables these future Biomedical Scientists to become truly enthusiastic about subjects that may otherwise seem dry theoretically...
Intomics A/S enters a new collaboration with a leading Swiss-based biopharmaceutical company to accelerate a better understanding of the pathological processes underlying human neurodegenerative diseases at the molecular level through systems biology.
Intomics A/S and Actelion Pharmaceuticals Ltd have entered a new collaboration with the aim of developing a systems biology view of neurodegeneration. Intomics will assist Actelion with expertise, experience and tools in analyzing and advancing knowledge based on data specifically related to neurodegeneration...
The link between blood flow in the retina and the development of glaucoma can now be measured accurately for the first time.
This was made possible by the further development of an established measurement method, optical coherence tomography (OCT), which enables the visual assessment of the retina and has thus become an important diagnostic tool. It does not, however, provide any information about retinal function...
XEI Scientific Inc, manufacturer of the popular EVACTRON® De-Contaminator™ Plasma Cleaning System for electron microscopes and other vacuum chambers, was awarded a US patent on May 6, 2014, for a device to load TEM sample holders into a vacuum chamber.
XEI is pleased to announce that the company has been granted a new US patent # US8716676B2 which describes a new device to load TEM sample holders into a vacuum chamber. It was invented by invented by George Safar of the XEI development team. This device allows the TEM sample stage and holder to be easily inserted into XEI’s desktop Evactron® CombiClean™ plasma cleaner without fear of bumping the end of the holder or specimen when it enters...
Synbiosis, a world-leading manufacturer of automated microbiological systems, is pleased to announce its ProtoCOL 3 automated inhibition zone measurement system is being used at a major UK based microbiological contract testing laboratory to significantly speed up throughput of their antibiotic susceptibility testing.
Microbiologists at the contract testing laboratory are using a ProtoCOL 3 and SynStats software to measure zones, determine each antibiotic’s potency from measurement data and produce a result in an instant. Using the ProtoCOL 3 and SynStats software in combination is helping microbiologists at this contract testing laboratory to significantly increase their throughput when determining the efficacy of new antibiotics...
Studylog Animal Study Software Named Best of Show Finalist at the 2014 Bio-IT World Conference
Studylog Systems today announced that its Studylog Animal Study Workflow Software was named a Best of Show Finalist in the Web-Based Services and Software category at the Bio-IT World Conference & Expo 2014. Only three products were awarded this distinction, which is imparted by the Cambridge Healthtech Institute, and Studylog has the honor of being the only animal research software to be a Best of Show Finalist in the past decade....
Read MoreIntroduction to Solid State ChIP TechnologyJun 6, 2014
A new instructional video from Porvair Sciences explains exactly how to conduct a ChIP assay for epigenetic research starting from a confluent monolayer of human cells.
This live demonstration of the Chromatin Immunoprecipitation (ChIP) assay uses Porvair’s innovative solid-state ChIP kit – Chromatrap 96. The video was prepared to inform researchers of an optimised protocol for preparing fresh chromatin from a dish of growing cells and how to verify the quality of the chromatin recovered...
Malvern Instruments Ltd. (Malvern, UK) announced today that it has entered into an agreement with GE Healthcare Life Sciences to acquire the company’s MicroCal™ microcalorimetry business. Financial terms were not disclosed. The acquisition, which is subject to regulatory approvals, is expected to complete in the third quarter of 2014.
MicroCal has a 30-year history of developing and supplying easy-to-use microcalorimeters. These systems are used extensively to study proteins and other biomolecules in drug discovery and development. The acquisition of MicroCal will further strengthen Malvern’s rapidly expanding portfolio of analytical solutions for customers in core pharmaceutical and biopharmaceutical markets. Within Malvern, MicroCal will retain its key location in Northampton, Massachusetts and will become an integral part of the Malvern business.
LGC today announced that they have been awarded a two-year contract by the Ministry of Defence (MOD) to provide DNA Testing Services to assist with the identification of historic remains recovered from battlefields and aircraft crash sites.
The contract let on behalf of the Ministry of Defence Joint Casualty and Compassionate Centre (JCCC) will assist the work undertaken by the JCCC’s Commemorations team in their efforts to positively identify the remains of British Service personnel recovered from battlefields, or other sites, arising from conflicts in the 20th Century....
The new Vertical Maxi Z is the latest Clarit-E® innovation from Alpha Laboratories for large format vertical gel electrophoresis.
This versatile system has been designed to save time in set up and provide high quality performance across a variety of separations. Maxi Z has innovative, new vertical screw-clamp technology within the PAGE insert that requires only four screws to secure four 20x20cm gels. This makes set up extremely easy and rapid compared to traditional clamping configurations requiring up to 24 screws to secure just two glass plates...
The Clinical and Laboratory Standards Institute (CLSI) has published a new report—Understanding the Cost of Quality in the Laboratory (QMS20-R)—which focuses on understanding and managing the different types of quality costs that affect the laboratory.
QMS20-R presents an initial approach laboratories can take to identify quality costs and remove unnecessary expense from laboratory processes. Laboratories are cognizant of the quality of examination results and laboratory services they provide. Yet many nonmanagement laboratory staff members are unaware of the quality of the laboratory's financial status, and believe that staying within budget is sufficient...
Porvair Sciences has announced a new 5-layer cell culture flask developed to fulfil the need of the growing number of applications that require large numbers of cells.
While single layer flasks are well proven for small-scale cell culture scale up, their use can become laborious and time-consuming when large numbers of cells are required. Offering a sterile growth area of 870cm2 in a compact footprint - Porvair's new 5-layer cell culture flask offers a high performance solution to this application need...
Matrix Hazardous Waste Tracker from Autoscribe simplifies hazardous waste management by tracking work and samples to comply with EU / EWC / Environment Agency regulations.
This Windows-based system features a dual web/Windows user interface and allows the registration of hazardous waste items, progress/status checking, chain of custody management and reporting, lookup of EWC lists and consignment of hazardous waste. Details of carrier, consignee and users, with their associated authority, are all stored within the system...
Magritek, a leading worldwide provider of compact NMR and MRI instruments, have released three new applications notes which showcase the use of their Spinsolve Benchtop NMR Spectrometer.
Magritek has released three new applications notes to illustrate the versatility of their Spinsolve family of cost-effective benchtop NMR spectrometry solutions. Spinsolve uses standard 5 mm OD NMR test tubes, exactly the same as high field instruments, so sample handling is familiar and convenient. Spinsolve can be deployed in the lab where immediate results may now be obtained...
Analytik, leading suppliers of innovative analytical instrumentation, announce the SciAps Inspector 500 SWIR Raman system for the pharmaceutical industry.
Analytik has announced the UK and Ireland release of the SciAps Inspector 500 SWIR Raman system for the pharmaceutical analysis of API’s and excipients including cellulose-based materials like Microcrystalline Cellulose (MCC’s), Croscarmellose, nutrients like Folic Acid; and other complex molecules. The Inspector 500, featuring shortwave-infrared Raman technology, offers a new choice in handheld Raman analysers...
AMSBIO announces the introduction of CRISPR/Cas9 - a full gene editing tool designed to produce a genetically modified cell using any mammalian cell line and targeting any gene.
CRISPR/Cas9 is revolutionizing the field of genomic editing by providing scientists with a powerful tool able to change any gene, in any cell in a highly targeted manner and without introducing foreign DNA. The benefits of CRISPR/Cas9 over previous forms of gene editing, such as TALENs and zinc finger, are that it is much simpler to implement and has higher efficiency at performing bi-allelic gene modifications...
Dr Paul Gleeson and Prof Chanin Nantasenamat on Dotmatics’ Tools and their Research.
Dotmatics, a leading provider of scientific informatics solutions and services to the academic, pharmaceutical and biotechnology industries, reported today that its premium data analysis and visualisation software, Vortex, is being used by university research groups in Thailand to further their scientific research in diverse fields. Dotmatics’ Vortex is designed to assist scientists gain a deeper understanding of their data and help to draw meaningful conclusions in an efficient way...
Cresset, innovative provider of computational chemistry software and services, announces its annual user meetings, ‘Field Based Chemistry North America’ and ‘Field Based Chemistry Europe’.
Both meetings combine scientific presentations, product updates, and news on the latest Cresset research. There are also free expert training sessions for Cresset products at each meeting. The North America meeting takes place on June 11th, 2014 in Cambridge, MA, USA. Presentations will be given by Novartis, Retrophin, Harvard Medical School, leading academics and Cresset scientists...
Markes International (Llantrisant, UK) has recently announced the latest technological improvements to its range of thermal desorption (TD) instruments, which further extend the application range and enhance productivity.
The first improvement is to allow much higher-concentration samples to be analysed in the same sequence as low-concentration samples. The new changes mean users can allow only a tiny fraction of the original sample into the analytical instrument. Markes’ Product Manager, Steve Davies, explained “The enhanced electronic mass flow control technology now implemented across Markes’ range of thermal desorbers allows split ratios from zero to 125,000:1 for routine TD–GC methods...
FFEI Life Science has successfully concluded phase I of the BiognostiX project with a symposium to share the results of this 3-year EU funded FP7 research programme.
Delegates to the event, held at the Hauser Forum, Cambridge, UK on Thursday 27 February. Led by FFEI, the BiognostiX Consortium has developed a radical new approach to performing diagnostic tests at point-of-use, with potential applications in veterinary, agri-food and human diagnostics. The BiognostiX technology uses a multiplex microfluidic platform and newly invented Immuno-Ink to deliver fast, flexible, single-use tests in a format that anyone can use...
Approximately 45.000 new cases are diagnosed each year together in the US and Europe. MM is mainly a disease of elderly people with age at diagnosis between 65-70 years. During the meeting, recently developed approaches for diagnosis and monitoring will be presented. Gene-expression-profiling to detect molecular subgroups with a different prognosis and high-throughput-sequencing to identify new genetic lesions will be discussed...
The Technische Universität München, or Technical University of Munich (TUM), is a research university with campuses in Munich, Garching and Freising-Weihensstephan, Germany. The TUM is one of the most research-focused universities in Europe and has been ranked 11th in the Academic Ranking of World Universities 2014. The TUM features a strong, characteristic profile in the fields of Science and Engineering...
In recognition of NHS requirements, Coventry can now offer its Biomedical Science degree students practical experience of real-life clinical instrumentation and applications. Consequently, this enables these future Biomedical Scientists to become truly enthusiastic about subjects that may otherwise seem dry theoretically...
Intomics A/S and Actelion Pharmaceuticals Ltd have entered a new collaboration with the aim of developing a systems biology view of neurodegeneration. Intomics will assist Actelion with expertise, experience and tools in analyzing and advancing knowledge based on data specifically related to neurodegeneration...
This was made possible by the further development of an established measurement method, optical coherence tomography (OCT), which enables the visual assessment of the retina and has thus become an important diagnostic tool. It does not, however, provide any information about retinal function...
XEI is pleased to announce that the company has been granted a new US patent # US8716676B2 which describes a new device to load TEM sample holders into a vacuum chamber. It was invented by invented by George Safar of the XEI development team. This device allows the TEM sample stage and holder to be easily inserted into XEI’s desktop Evactron® CombiClean™ plasma cleaner without fear of bumping the end of the holder or specimen when it enters...
Microbiologists at the contract testing laboratory are using a ProtoCOL 3 and SynStats software to measure zones, determine each antibiotic’s potency from measurement data and produce a result in an instant. Using the ProtoCOL 3 and SynStats software in combination is helping microbiologists at this contract testing laboratory to significantly increase their throughput when determining the efficacy of new antibiotics...
This live demonstration of the Chromatin Immunoprecipitation (ChIP) assay uses Porvair’s innovative solid-state ChIP kit – Chromatrap 96. The video was prepared to inform researchers of an optimised protocol for preparing fresh chromatin from a dish of growing cells and how to verify the quality of the chromatin recovered...
MicroCal has a 30-year history of developing and supplying easy-to-use microcalorimeters. These systems are used extensively to study proteins and other biomolecules in drug discovery and development. The acquisition of MicroCal will further strengthen Malvern’s rapidly expanding portfolio of analytical solutions for customers in core pharmaceutical and biopharmaceutical markets. Within Malvern, MicroCal will retain its key location in Northampton, Massachusetts and will become an integral part of the Malvern business.
This versatile system has been designed to save time in set up and provide high quality performance across a variety of separations. Maxi Z has innovative, new vertical screw-clamp technology within the PAGE insert that requires only four screws to secure four 20x20cm gels. This makes set up extremely easy and rapid compared to traditional clamping configurations requiring up to 24 screws to secure just two glass plates...
QMS20-R presents an initial approach laboratories can take to identify quality costs and remove unnecessary expense from laboratory processes. Laboratories are cognizant of the quality of examination results and laboratory services they provide. Yet many nonmanagement laboratory staff members are unaware of the quality of the laboratory's financial status, and believe that staying within budget is sufficient...
While single layer flasks are well proven for small-scale cell culture scale up, their use can become laborious and time-consuming when large numbers of cells are required. Offering a sterile growth area of 870cm2 in a compact footprint - Porvair's new 5-layer cell culture flask offers a high performance solution to this application need...
This Windows-based system features a dual web/Windows user interface and allows the registration of hazardous waste items, progress/status checking, chain of custody management and reporting, lookup of EWC lists and consignment of hazardous waste. Details of carrier, consignee and users, with their associated authority, are all stored within the system...
Magritek has released three new applications notes to illustrate the versatility of their Spinsolve family of cost-effective benchtop NMR spectrometry solutions. Spinsolve uses standard 5 mm OD NMR test tubes, exactly the same as high field instruments, so sample handling is familiar and convenient. Spinsolve can be deployed in the lab where immediate results may now be obtained...
Analytik has announced the UK and Ireland release of the SciAps Inspector 500 SWIR Raman system for the pharmaceutical analysis of API’s and excipients including cellulose-based materials like Microcrystalline Cellulose (MCC’s), Croscarmellose, nutrients like Folic Acid; and other complex molecules. The Inspector 500, featuring shortwave-infrared Raman technology, offers a new choice in handheld Raman analysers...
CRISPR/Cas9 is revolutionizing the field of genomic editing by providing scientists with a powerful tool able to change any gene, in any cell in a highly targeted manner and without introducing foreign DNA. The benefits of CRISPR/Cas9 over previous forms of gene editing, such as TALENs and zinc finger, are that it is much simpler to implement and has higher efficiency at performing bi-allelic gene modifications...
Dotmatics, a leading provider of scientific informatics solutions and services to the academic, pharmaceutical and biotechnology industries, reported today that its premium data analysis and visualisation software, Vortex, is being used by university research groups in Thailand to further their scientific research in diverse fields. Dotmatics’ Vortex is designed to assist scientists gain a deeper understanding of their data and help to draw meaningful conclusions in an efficient way...
Both meetings combine scientific presentations, product updates, and news on the latest Cresset research. There are also free expert training sessions for Cresset products at each meeting. The North America meeting takes place on June 11th, 2014 in Cambridge, MA, USA. Presentations will be given by Novartis, Retrophin, Harvard Medical School, leading academics and Cresset scientists...
The first improvement is to allow much higher-concentration samples to be analysed in the same sequence as low-concentration samples. The new changes mean users can allow only a tiny fraction of the original sample into the analytical instrument. Markes’ Product Manager, Steve Davies, explained “The enhanced electronic mass flow control technology now implemented across Markes’ range of thermal desorbers allows split ratios from zero to 125,000:1 for routine TD–GC methods...
Delegates to the event, held at the Hauser Forum, Cambridge, UK on Thursday 27 February. Led by FFEI, the BiognostiX Consortium has developed a radical new approach to performing diagnostic tests at point-of-use, with potential applications in veterinary, agri-food and human diagnostics. The BiognostiX technology uses a multiplex microfluidic platform and newly invented Immuno-Ink to deliver fast, flexible, single-use tests in a format that anyone can use...