Cresset, innovative provider of computational chemistry software and services, is pleased to announce that the Centre for Chemical Biology and Therapeutics (CCBT) at The Institute for Stem Cell Biology and Regenerative Medicine (inStem), a state-of-the-art research institute in Bangalore, India, has taken a three year license for use of Cresset’s Forge and Spark software tools for lead optimization and identification.
The CCBT, which is directed by Prof. Ashok Venkitaraman (University of Cambridge) in an international collaboration between Cambridge and inStem, seeks to pioneer new approaches for chemical biology and therapeutics through the development of new methods for small-molecule drug discovery. Cresset and Forge will be used in the new computational chemistry group in the CCBT. Dr. Kavitha Bharatham, who leads the...
Today GENALICE proudly announced the scheduled release of an upgraded version of its Next-Generation Sequencing (NGS) DNA data processing software solution GENALICE MAP, at the European Society of Human Genetics conference in Milan later this week.
Featuring the new 5-minute Variant Caller, the company is now capable of processing the DNA data of an entire human genome with 40x depth within 30 minutes on a commodity dual Intel Xeon E5 server. The company commercializes its software in a turnkey appliance, the GENALICE VAULT. This all-in-one bioinformatics tool is preloaded with the company’s breakthrough DNA processing solution GENALICE MAP...
Two of the world’s leading flow chemistry systems as well as the latest addition to the field of photochemistry technology will be on show at Chemspec Europe on 18-19 June and IMRET (Conference on Microreaction Technology) 23-25 June.
Both events take place in Budapest, Hungary. Manufactured by UK firm Vapourtec, the E-Series and R-Series continuous process technologies are already established as pioneering systems within flow chemistry and the UV-150 photochemical reactor, launched earlier this year, is making its mark with those interested in photochemistry. Vapourtec founder and MD Duncan Guthrie explained: “Chemspec Europe and IMRET are prime opportunities for chemists across the globe to uncover...
Thermo Fisher Scientific has developed an on-line solid-phase extraction–high-performance liquid chromatography (SPE-HPLC) method combined with ultraviolet (UV) absorbance detection for the simple and sensitive determination of tigecycline in a cell lysate sample.
Application Note 1074:Determination of Tigecycline in a Cell Lysate demonstrates that this approach, performed on a rapid separation LC (RSLC) system controlled by data management software, detects trace amounts of tigecycline in tigecycline-treated cells, concentrations so low that they cannot be assayed using a routine HPLC-UV detection method. The prevalence of multidrug-resistant bacteria in hospitals underscores the need for...
Scientists at Nuclea Biotechnologies, Inc. and Thermo Fisher Scientific are pooling their expertise to develop novel multiplexed research methods for high-throughput quantification of native insulin and its therapeutic analogs.
Monitoring the levels of these markers may be useful in predicting the response to therapy for Type 2 diabetes. Nuclea has extensive experience in developing and commercializing biomarkers and clinical tests. The Thermo Fisher Scientific Biomarker Research Initiatives in Mass Spectrometry (BRIMS) Center has successfully collaborated with numerous leading clinical researchers to apply mass spectrometry (MS) to biomarker discovery...
Analytik, leading suppliers of innovative analytical instrumentation, report on research work at the Babraham Institute to study protein microarrays using the GeSiM Nano-Plotter system.
Affinomics is an EC FP7 Collaborative Project set up to initiate the generation of a proteome-wide binder collection. To this end, the project integrates the expertise and technologies available in leading European centres in order to create an efficient pipeline for target and binder production, validation and quality control. It is coordinated by Dr Mike Taussig of the Protein Technology Group at the Babraham Institute near Cambridge...
This week an insight into the design strengths and manufacturing skills of British laboratory autoclave producer Priorclave are revealed in a new Corporate Video.
The short video clip takes the viewer on a journey that every autoclave built takes at the company’s manufacturing centre in South East London, from the design studio, through component production to final assembly, test and make-ready for delivery. The new Corporate Video also gives a brief look into the superb customer support programme from a dedicated service team that extends around the world...
The Western European next-generation sequencing (NGS) market is poised for steady growth, owing to the emergence of new applications such as non-invasive prenatal testing and comprehensive oncology panels.
NGS manufacturers are further tapping into this space by forming partnerships with molecular diagnostic companies to quicken NGS adoption in clinics, particularly for oncology-based testing. New analysis from Frost & Sullivan, Western European Next-generation Sequencing Markets, finds that the market earned revenues of $381.9 million in 2013 and estimates this to reach $697.3 million in 2018...
LPW Technology, a global leader in the development and supply of optimised metal powders for additive manufacturing (AM), has formally established a US subsidiary, LPW Technology Inc.
Opening in June 2014, the LPW Technology Inc. office will be situated in Pittsburgh, Pennsylvania, and will provide local support and sales to a growing number of customers in the US. Announcing the news, Phil Carroll, Managing Director of LPW Technology, said, “Our global client base continues to show encouraging growth and the time feels right for this significant expansion into the US...
The application of molecular technology in clinical diagnosis is a rapidly developing area and is predicted to greatly improve the speed, efficiency and accuracy of diagnostic medicine.
A book looking at the challenges within molecular diagnostics, “Molecular Diagnostics: Current Research and Applications”, edited by Dr Jim Huggett and Dr Justin O’Grady, is published this month by Caister Academic Press. It is essential reading for anyone involved in the development or application of molecular diagnostics and is recommended for all clinical diagnostics laboratories...
Markes International’s Select-eV variable-energy ion-source technology has received an Honourable Mention at the Pittcon Editors’ Awards, following its introduction earlier this year.
Pittcon, The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, is widely regarded as one of the world’s best trade shows for innovations in analytical chemistry. It gives attendees the opportunity to observe many analytical instrument developments, all under one roof. This year, the conference attracted 16,200 attendees, including 935 exhibitors from 32 countries across 1,763 booths....
EKF Diagnostics, the global diagnostics company, today confirms the growing weight of independent scientific evidence as validation that soluble TNF Receptors 1 and 2 are strong biomarkers of progressive Diabetic Kidney Disease (DKD).
EKF affirms that the markers can be reliably used as diagnostic tests to predict end-stage renal disease (ESRD) - one of the greatest mortality risks in diabetics - up to 10 years in advance. Since signing an exclusive license agreement for this novel kidney biomarker technology with the prestigious Joslin Diabetes Center (Boston, USA) in 2012, EKF Diagnostics has worked in partnership with Joslin and other key diabetic research centers to further...
SP Scientific has announced further investment into its state-of-the-art training and demonstration laboratory facility at its Warminster, PA site.
The demonstration laboratory will now be able to offer customers and potential clients the opportunity to book an appointment to test / demo SP Scientific’s latest products including the AdVantage Pro, Benchtop Pro and LyoStar 3 Freeze Dryer with SMART™, ControLyo™ and TDLAS. If required, specialty items can be brought in upon customer request. The 1200 square foot facility will also continue to...
Nottingham-based Scientific Laboratory Supplies Ltd (SLS), the UK’s largest independent supplier of scientific equipment, chemicals and consumables has been confirmed as the single source distributor for the public sector Laboratory Consumables contract by UK Shared Business Services Ltd (UK SBS).
Under the contract, which SLS won ahead of two strong global competitor organisations, the company will manage the delivery of all consumable items to all participating public body organisations. The company expects to recruit a minimum of 5 internal staff and 4 external support staff as a direct result of the contract win. UK SBS is a key vehicle for meeting the challenge facing UK public services to increase efficiency...
Thermo Fisher Scientific has developed a high-performance liquid chromatography (LC) method that simplifies determination of clenbuterol, ractopamine, and phenolethanolamine in meat using on-line solid-phase extraction (SPE) and ultraviolet absorbance detection.
Application Brief (AB) 154: Rapid and Sensitive Determination of Clenbuterol, Ractopamine, and Phenolethanolamine in Meatdemonstrates that this method, performed using a dual rapid separation LC system controlled by data management software, achieves method detection limits equivalent to those obtained by mass spectrometry (MS). Additionally, this approach offers the advantages of...
The Institute of Genetics and Development of Rennes (IGDR), France reports on how, using a VIAFLO 96 handheld multichannel pipette from INTEGRA, they have been able to improve the efficiency and speed with which they replicate yeast strain collections and perform genetic screens in 96 well plates.
The Institute of Genetics and Development of Rennes is one of the major biological research institutes in France. The objective of the IGDR is to develop research of excellence in areas including Genetics, Cell Biology and Developmental Biology. Employing 20 teams of scientists – current research interests at IGDR include investigations into cell polarity, cell cycle, signalisation, membrane trafficking, RNA stability, splicing...
Stepping up calls for a public interest test on major takeovers, Britain’s largest union, Unite expressed fears that Pfizer ‘could be back’ in the coming months despite the company conceding defeat in its takeover bid of AstraZeneca.
Under Takeover Panel rules, talks on a tie up could be reignited in three months if AstraZeneca invites Pfizer back to the negotiating table. If that does not happen, then Pfizer can make a new unsolicited bid in November later this year. Commenting, Tony Burke Unite assistant general secretary said: “Pfizer failed to convince hardly anyone that their bid was good for science and would secure skilled jobs and...
Link Technologies Ltd, a specialist oligonucleotide reagent manufacturer, has announced the availability of a novel vitamin modifier, which has shown in initial tests to have the potential of improving cell delivery of oligonucleotides.
The new reagent, 5’-Niacin-CE Phosphoramidite, is easily incorporated during solid phase oligo synthesis. The niacin-based modifier from Link offers several advantages over the use of conventional lipophilic delivery agents, including reduced risk of in vivo toxicity, and removes the necessity of cleaving the delivery reagent once in the cell. These benefits make vitamins, including niacin, an attractive method for the delivery...
The 6th Annual Next Generation Sequencing Congress is taking place on 20th & 21st November 2014 in London, UK.
It brings together over 400 senior experts to discuss crucial challenges in the next generation sequencing field. Topics covered include NGS technologies & platforms, NGS data analysis technologies & platforms, NGS for cancer drug development and NGS clinical applications & diagnostics.
A portable eye-scanning camera that could prevent blindness in millions of diabetes sufferers is being developed in Scotland, thanks to backing from angel investors.
The handheld device, built by Rosyth-based company Epipole, is the first portable and affordable camera capable of diagnosing diabetic retinopathy - a condition responsible for two million cases of preventable blindness worldwide. Now Dr Craig Robertson, 45, the managing director and founder of Epipole, has signed a £400,000 investment deal which will enable his firm to develop a single working prototype into a commercial reality. As well as being a landmark for Epipole, it is also the first major deal for newly launched Scottish angel syndicate, Lancaster Capital...
With Olympus’ unique GEM interface integrated into the latest release of the cellSens imaging software, executing even the most intricate life science imaging experiments is now realised with outstanding ease and efficiency.
Personalised automation is the key to managing complex multi-dimensional experiments, and the latest Olympus cellSens imaging software (version 1.11) seamlessly controls motorised hardware to allow effortless set-up of complex acquisition sequences and protocols. The unique Graphical Experiment Manager (GEM) interface allows the user to "draw" their experimental schematic on-screen with...
Seward Ltd., manufacturer of the world leading range of original Stomacher® paddle blenders and accessories used in sample preparation for microbiological analysis, confirms the use of its Stomacher® in USDA meat speciation protocols [1].
Following recent high profile meat provenance scandals, Seward has noted an increase in enquiries on the application of its technology for the delivery of contamination free, viable antigen samples. The complexity and globalisation of the food industry makes the management of the food chain from farm to fork increasingly difficult. The contamination of meat ingredients with unintended species in the UK has been very costly in reputations and profits....
The CCBT, which is directed by Prof. Ashok Venkitaraman (University of Cambridge) in an international collaboration between Cambridge and inStem, seeks to pioneer new approaches for chemical biology and therapeutics through the development of new methods for small-molecule drug discovery. Cresset and Forge will be used in the new computational chemistry group in the CCBT. Dr. Kavitha Bharatham, who leads the...
Featuring the new 5-minute Variant Caller, the company is now capable of processing the DNA data of an entire human genome with 40x depth within 30 minutes on a commodity dual Intel Xeon E5 server. The company commercializes its software in a turnkey appliance, the GENALICE VAULT. This all-in-one bioinformatics tool is preloaded with the company’s breakthrough DNA processing solution GENALICE MAP...
Both events take place in Budapest, Hungary. Manufactured by UK firm Vapourtec, the E-Series and R-Series continuous process technologies are already established as pioneering systems within flow chemistry and the UV-150 photochemical reactor, launched earlier this year, is making its mark with those interested in photochemistry. Vapourtec founder and MD Duncan Guthrie explained: “Chemspec Europe and IMRET are prime opportunities for chemists across the globe to uncover...
Monitoring the levels of these markers may be useful in predicting the response to therapy for Type 2 diabetes. Nuclea has extensive experience in developing and commercializing biomarkers and clinical tests. The Thermo Fisher Scientific Biomarker Research Initiatives in Mass Spectrometry (BRIMS) Center has successfully collaborated with numerous leading clinical researchers to apply mass spectrometry (MS) to biomarker discovery...
Affinomics is an EC FP7 Collaborative Project set up to initiate the generation of a proteome-wide binder collection. To this end, the project integrates the expertise and technologies available in leading European centres in order to create an efficient pipeline for target and binder production, validation and quality control. It is coordinated by Dr Mike Taussig of the Protein Technology Group at the Babraham Institute near Cambridge...
The short video clip takes the viewer on a journey that every autoclave built takes at the company’s manufacturing centre in South East London, from the design studio, through component production to final assembly, test and make-ready for delivery. The new Corporate Video also gives a brief look into the superb customer support programme from a dedicated service team that extends around the world...
NGS manufacturers are further tapping into this space by forming partnerships with molecular diagnostic companies to quicken NGS adoption in clinics, particularly for oncology-based testing. New analysis from Frost & Sullivan, Western European Next-generation Sequencing Markets, finds that the market earned revenues of $381.9 million in 2013 and estimates this to reach $697.3 million in 2018...
Opening in June 2014, the LPW Technology Inc. office will be situated in Pittsburgh, Pennsylvania, and will provide local support and sales to a growing number of customers in the US. Announcing the news, Phil Carroll, Managing Director of LPW Technology, said, “Our global client base continues to show encouraging growth and the time feels right for this significant expansion into the US...
Pittcon, The Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, is widely regarded as one of the world’s best trade shows for innovations in analytical chemistry. It gives attendees the opportunity to observe many analytical instrument developments, all under one roof. This year, the conference attracted 16,200 attendees, including 935 exhibitors from 32 countries across 1,763 booths....
EKF affirms that the markers can be reliably used as diagnostic tests to predict end-stage renal disease (ESRD) - one of the greatest mortality risks in diabetics - up to 10 years in advance. Since signing an exclusive license agreement for this novel kidney biomarker technology with the prestigious Joslin Diabetes Center (Boston, USA) in 2012, EKF Diagnostics has worked in partnership with Joslin and other key diabetic research centers to further...
The demonstration laboratory will now be able to offer customers and potential clients the opportunity to book an appointment to test / demo SP Scientific’s latest products including the AdVantage Pro, Benchtop Pro and LyoStar 3 Freeze Dryer with SMART™, ControLyo™ and TDLAS. If required, specialty items can be brought in upon customer request. The 1200 square foot facility will also continue to...
Under the contract, which SLS won ahead of two strong global competitor organisations, the company will manage the delivery of all consumable items to all participating public body organisations. The company expects to recruit a minimum of 5 internal staff and 4 external support staff as a direct result of the contract win. UK SBS is a key vehicle for meeting the challenge facing UK public services to increase efficiency...
The Institute of Genetics and Development of Rennes is one of the major biological research institutes in France. The objective of the IGDR is to develop research of excellence in areas including Genetics, Cell Biology and Developmental Biology. Employing 20 teams of scientists – current research interests at IGDR include investigations into cell polarity, cell cycle, signalisation, membrane trafficking, RNA stability, splicing...
Under Takeover Panel rules, talks on a tie up could be reignited in three months if AstraZeneca invites Pfizer back to the negotiating table. If that does not happen, then Pfizer can make a new unsolicited bid in November later this year. Commenting, Tony Burke Unite assistant general secretary said: “Pfizer failed to convince hardly anyone that their bid was good for science and would secure skilled jobs and...
The new reagent, 5’-Niacin-CE Phosphoramidite, is easily incorporated during solid phase oligo synthesis. The niacin-based modifier from Link offers several advantages over the use of conventional lipophilic delivery agents, including reduced risk of in vivo toxicity, and removes the necessity of cleaving the delivery reagent once in the cell. These benefits make vitamins, including niacin, an attractive method for the delivery...
The handheld device, built by Rosyth-based company Epipole, is the first portable and affordable camera capable of diagnosing diabetic retinopathy - a condition responsible for two million cases of preventable blindness worldwide. Now Dr Craig Robertson, 45, the managing director and founder of Epipole, has signed a £400,000 investment deal which will enable his firm to develop a single working prototype into a commercial reality. As well as being a landmark for Epipole, it is also the first major deal for newly launched Scottish angel syndicate, Lancaster Capital...
Personalised automation is the key to managing complex multi-dimensional experiments, and the latest Olympus cellSens imaging software (version 1.11) seamlessly controls motorised hardware to allow effortless set-up of complex acquisition sequences and protocols. The unique Graphical Experiment Manager (GEM) interface allows the user to "draw" their experimental schematic on-screen with...
Following recent high profile meat provenance scandals, Seward has noted an increase in enquiries on the application of its technology for the delivery of contamination free, viable antigen samples. The complexity and globalisation of the food industry makes the management of the food chain from farm to fork increasingly difficult. The contamination of meat ingredients with unintended species in the UK has been very costly in reputations and profits....