Thermo Fisher Scientific today announced that its San Jose, California facility has registered with the U.S. Food and Drug Administration (FDA) as a medical device establishment.

The site has established a quality in accordance with the FDA Quality System Regulations to design and manufacture devices for analyzing samples from patients for in vitro diagnostic use. “Last year we achieved ISO 13485 certification for the San Jose site, and this FDA registration is the next major milestone in our ongoing initiative to develop Class 1 mass spectrometry-based instruments for the clinical market,” said Dan Shine, president, chromatography and mass spectrometry, Thermo Fisher Scientific... 

Laboratories analyzing food, the environment, and biological samples for compounds like dioxins, PCBs, pesticides, steroids and other challenging analytes now have access to a new generation of GC-MS/MS from Thermo Fisher Scientific, designed to deliver more sensitivity at faster speeds than its predecessor.

The new Thermo Scientific TSQ 8000 Evo triple quadrupole GC-MS is making its debut at the 62^nd ASMS Conference on Mass Spectrometry and Allied Topics at the company’s hospitality suite: Holiday, Baltimore Hilton. The TSQ 8000 Evo system improves on the features of its predecessor, the TSQ 8000, with new EvoCell technology, demonstrated in company-run experiments to triple selected reaction monitoring (SRM) transition rates without compromising sensitivity...

Laboratories analyzing environmental, clinical research/toxicological, and food samples have a powerful new data tool expected to save time and money while identifying compounds with high levels of confidence.  

Thermo Fisher Scientific announces its high resolution accurate mass (HRAM) spectral library at the 62^nd ASMS Conference on Mass Spectrometry and Allied Topics. “This is a true library with full, high-resolution spectra for every compound it contains,” said Jennifer Massi, program manager, environmental and food safety for Thermo Fisher Scientific. “In fact, we ran multiple MS/MS spectra for each compound, and each was analyzed at multiple collision energies. This is designed to enhance method flexibility and confidence in results.”...

Novel Program Increases Lab Accuracy and Unknown Compound Identification with Single Quadrupole Instrumentation

Cerno Bioscience and Agilent Technologies, Inc. (NYSE: A) today announced Agilent will distribute Cerno Bioscience’s MassWorks™ calibration and analysis software with all Agilent GC/MSD systems. This novel calibration technology increases the mass accuracy of Agilent's single quadrupole GC/MSD to enable unknown compound identification. This process normally requires more complex instruments such as Time-of-Flight (TOF) mass spectrometers "Making Cerno MassWorks directly available to GC/MSD users through Agilent channels opens the qualitative power of accurate mass information to...

Merck Millipore, has launched Simplicon™ RNA Reprogramming Technology, which uses synthetic self-replicating RNA to create large numbers of human induced pluripotent stem cells (iPSCs) using a single transfection step.

This efficient reprogramming of somatic cells is accomplished without viral intermediates or host genome integration, offering a more defined and safer system for iPSC generation. "For stem cell researchers using iPSCs to study disease, differentiation and regenerative medicine, there's a real need for a reprogramming method that's as efficient as virus-based techniques yet as safe as non-viral methods," said Christophe Couturier, Head of Bioscience, Merck Millipore...

The British Laboratory Managers Association has announced the dates for the next laboratory management training course.

It will be held at Brownsover Hall hotel, Rugby on 8^th & 9^th October 2014. The course which has already been run successfully twice before in 2013 is specifically aimed to help current and aspiring laboratory managers deal with the challenges they face in managing people in a modern day laboratory...

Tecan has introduced a Dual Z arm for the popular Cavro^® Omni Robot.

Available with a broad choice of lengths, orientations and options for all three axes, the Cavro Omni Robot is designed to combine precision OEM liquid handling with straightforward integration, and the launch of the Dual Z option provides instrument designers with even greater flexibility. The Dual Z option offers two independent pipetting channels in a single housing, doubling the robot’s liquid handling capacity without having to...

Waters Introduces Xevo G2-XS QTof and Xevo TQ-S micro Mass Spectrometers, Taking Benchtop Quantitative and Qualitative MS Applications to New Levels

Company also Expands ionKey/MS System to SYNAPT and Xevo Time-of-Flight Mass Spectrometers with New UPLC-Grade iKey Chemistries.
Waters Corporation (NYSE:WAT) today introduced two new Xevo® mass spectrometers and expanded the ionKey/MS System at the 62nd conference of the American Society of Mass Spectrometry (ASMS). The Waters® Xevo G2-XS mass spectrometer, a new high performance benchtop quadrupole time-of-flight (QTofTM) mass spectrometer, and the Xevo TQ-S micro, a new and compact benchtop tandem quadrupole mass spectrometer, take...

GENALICE has announced that the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre’s Molecular Diagnostics Centre has signed a contract for a larger model of the GENALICE VAULT, GENALICE’s Next-Generation Sequencing (NGS) data processing appliance.

This all-in-one bioinformatics appliance is preloaded with the ultra-fast and highly accurate NGS data processing software, GENALICE MAP. GENALICE recently announced the upgrade of its groundbreaking DNA processing solution to include Variant Calling. This upgrade makes GENALICE MAP a complete processing workflow. The product is specifically designed to support high volume DNA sequencing centers that require high throughput at high quality...

Qlucore Omics Explorer turns the world of bioinformatics software on its head.

It’s so easy to use that you will no longer be dependent on an expert in Bioinformatics to explore your data sets and verify your hypotheses. Now you can "Do It Yourself"! Qlucore Omics Explorer is next-generation bioinformatics software that combines powerful statistical methods with real time visualization and an intuitive user interface. With Qlucore Omics Explorer you immediately have a visual representation of all your results...

Available from your Techne Distributor

Special offer
Until July 31, you can buy a Techne Prime gradient thermal cycler at our lowest ever price. The Prime range offers a model for every application, from personal 30 wells to advanced 1536 well networks.

• ³Prime 48-well personal is now £1995 / €2395 / $3195
• Prime 96-well full size is now £2495 / €2995 / $3995
• Prime Elite premium is now £3200 / €3840 / $5120

The advent of nonwoven nanofibers is enabling the development of a new generation of highly sensitive filters. Surging global demand is creating a compelling need for improved production and quality control methods.

Currently, much of the industry is using old technology for process monitoring and control, yielding limited data. As a result, critical details that affect a filter’s performance are often overlooked because accurate performance data cannot be easily and quickly verified. Without SEM imaging, it is not possible to discern the important features during nanofiber filter design. The Fibermetric software supported on the Phenom desktop SEM is the first integrated system designed for submicron fiber development....

Scientists at Thermo Fisher Scientific and BioAnalytix, Inc., of Cambridge, MA, are combining their expertise to develop advanced analytical profiling platforms and applications to characterize biologic and biosimilar drugs.

Biologic drugs, such as therapeutic monoclonal antibodies, are extremely large and complex biomolecules, and represent one of the most significant areas in the pharmaceutical industry today. Minor differences in biologic structure from drug to drug, or from manufacturing lot to manufacturing lot, however, can profoundly affect these drugs’ safety and efficacy profiles...

Dr Rico Tabor leads the Soft Materials and Colloids Group in the School of Chemistry at Monash University.

Research focuses on several areas. At a fundamental level, the group is interested in exploring the interactions that cause aggregation and assembly, in everything from nanoparticles, droplets and graphene to proteins and cells. This ranges from quite fundamental studies of things like the van der Waals force (of quantum origin) and electrical double-layer interactions, right through to unwinding protein molecules and the forces experienced by...

J.G. Finneran Associates is a highly recognized, respected and independent, family-owned and operated glass and plastic manufacturer. 

A specialist in chromatography, biotechnology and environmental products which include glass and plastic vials, closures and accessories, the  patented 96-Well Multi-Tier™ Micro Plate System and accessories, VOA/EPA vials, and sampling bottles and jars – pre-cleaned and pre-cleaned/certified.  Their manufacturing operations located in Vineland, NJ, USA, combine the most modern and highly automated equipment with our own custom designed machinery to handle volume production while maintaining product integrity and the highest quality products in the industry.

Some of the UK’s brightest young scientists will be taking part in the Royal Society of Medicine’s Medical Innovations Summit on Saturday 5 July.

Eighteen-year old twin sisters Ameeta and Aneeta Kumar, winners of the UK Young Scientist of the Year competition, will describe their project to develop a diagnostic tool for identifying cancerous tumours at an early stage of development. Beating off competition from 4,000 other entries, the pair are now both considering a career in medicine. Also in her teens, Amber McCleary will explain how the anti-bacterial and healing properties of the copper-infused pyjamas she and inventor Paula Ward produced last year quite possibly saved the life of a new mother who had acquired MRSA from a caesarean section wound...

AFFiRiS halted clinical progression in Alzheimer patients upon treatment with AD04 in a phase II clinical study

AFFiRiS announced today the results of a phase II study in Alzheimer patients. AFFiRiS' proprietary compound AD04 is the first drug ever to demonstrate clinical and biomarker effects consistent with disease modification in Alzheimer patients. Upon treatment with AD04, effects consistent with disease modification were achieved for at least 18 months in 47 % of treated patients. This beneficial effect was dose dependent and more effective in early disease patients. Furthermore, prevention of hippocampal decline was correlated with the beneficial impact on clinical progression and...

A recently published study has highlighted the economic and clinical benefits of incorporating a near patient nucleic acid amplification test (NAAT) for Chlamydia trachomatis and Neisseria gonorrhoeae into genitourinary medicine clinics.

Sponsored by leading molecular diagnostics company Cepheid, this prospective study estimates savings of up to £11.75m per annum from the adoption of laboratory-standard POC NAATs, such as Cepheid’s Xpert^® CT/NG. Recent advances in technology have enabled the latest generation of in-clinic analysers – such as Cepheid’s GeneXpert^® series – to offer rapid, PCR-based testing at the point of patient care. This new generation of assays can provide laboratory quality results within...

New micro-volume probes from Jenway are designed for the accurate and reliable measurement of solutions in volumes as low as 150μl.

The micro-volume probes are available in two variants - the 4mm probe with a 120mm reach and the 6mm probe has a 180mm reach. The specific designs of each of the probes ensure their suitability for use in test tubes and small vessels, while the small shaft diameters allow for accurate readings in sample volumes as small as 150µl and 200µl respectively. Both probes are made from glass and can be used with any of the bench conductivity meters supplied by Jenway...

Anasys Instruments reports on EPFL’s latest research on lysozyme droplets and α-synuclein macromolecular aggregates illustrating application of the nanoscale AFM-IR technique to demonstrate α to β secondary structure transition associated with amyloid formation. 

Proteins aggregating into amyloid structures are involved in important neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease. During aggregation, initially monomeric proteins undergo internal structural rearrangement forming amyloid fibrils with a universal cross β -sheet quaternary structure. During fibrillation, several coexisting amyloidogenic species are formed and the study of these species would allow...

EKF Molecular Diagnostics, and GILUPI, an innovator in medical devices for in vivo isolation of rare cells directly from a patient’s blood stream, announce results from collaborative work using the GILUPI CellCollector^TM and EKF Molecular’s PointMan^TM DNA Enrichment technology.

The first results of the collaboration have successfully demonstrated the detection of gene mutations from as few as three or less cells isolated in a model in vitro system and from the blood of lung cancer patients.  PointMan DNA Enrichment was used to detect and analyse cells with known mutation status that had been collected on GILUPI CellCollectors under laboratory conditions.  The known mutations were those typically seen in...