The fluorescence imaging method was invented by Dr. Eric Betzig, group leader at the Janelia Research Campus in Ashburn, Virginia, USA. Bessel beam plane illumination microscopy allows high-speed 3D fluorescence imaging of living cellular and multicellular specimens with nearly isotropic spatial resolution, low photobleaching and low photodamage. The technology uses special beam conditioning of the light sheet illumination. Enabling...


Pi-Process Intensification have been acting as distributors for Vapourtec's R-Series systems for the past three years and will now also be distributing their E-Series system. Dr Reddy's Labs is one of a number of key customers. They recently took delivery of a second R-Series system, this time for their research lab in Hyderabad. The R-Series has a wide range of applications with more than 200 systems installed and already used...
CompacT SelecT is being routinely used to automatically culture and maintain a large range of cells in 24 and 96 transwell transport assay plates. With the system, researchers are setting up their cell culture seeding, feeding, expansion, plating and maintenance protocols to automatically produce consistent quality cells for extended periods of time. This flexible approach is allowing these scientists to have a constant supply of cell lines such as...
Chromatrap®, the novel solid-based matrix for ChIP assays, available from Porvair Sciences, has been successfully used to isolate high quality chromatin from a wide range of biological matrices by research groups around the world. Chromatrap® uses a solid phase porous polymer functionalised with either protein A or G, allowing the chromatin capture to be more sensitive and efficient than bead based methods. The Chromatrap spin column approach offers significant advantages...
The effectiveness of the technology, designed and produced by UK company Bioquell, has been extensively evaluated by the NHS. The system has been deployed globally during the current outbreak. The portable, automated system uses 35% hydrogen peroxide, which is distributed as a vapour throughout the decontamination area, ensuring full three-dimensional coverage. The peroxide is then removed, allowing admission of another patient within 90 minutes...
This research was presented at the launch of the British Science Festival held this week at the University of Birmingham, UK. The scientists looked at global data from 500,000 people from the mobile phone app Foursquare which details users’ specific locations and is a forum where they can share tips and comments about a particular venue with their friends. The research team wanted to study the ‘temporal’ habits of people relating to food, for example...
Merck will acquire all of the outstanding shares of Sigma-Aldrich for $140 per share in cash. The agreed price represents a 37% premium to the latest closing price of $102.37 on September 19, 2014, and a 36% premium to the one-month average closing price. The transaction is expected to be immediately accretive to Merck’s EPS pre and EBITDA margin. Merck expects to achieve annual synergies of approximately €260 million (approximately $340 million), which should be fully realized within three years after closing....
Despite having the most comprehensive range of laboratory autoclaves there is always someone who wants something different and that is exactly what brought about the development and production by Priorclave of the H60, an autoclave with a horizontal 60 litre capacity chamber....
The UltraVap Mistral from Porvair Sciences makes it easy to integrate an automatic dry down step into your automated liquid handling protocol. Optimised to work with most commercial robotic liquid handling systems the UltraVap Mistral represents the leading edge in automated microplate drying technology. Until 30th November 2014 - Porvair Science is offering a £1000 trade-in value on any evaporator system against the purchase of a new UltraVap Mistral....
The visualization and analysis of pores is easier than ever before with the Phenom desktop SEM and the PoroMetric software. The combination of speed, ease of use and superb imaging quality of the Phenom and image pore analysis software of PoroMetric creates a powerful tool for inspecting wide range of samples like filters and membranes...
Dr Chris Doughty is a lecturer in ecosystem ecology within the Environmental Change Institute (ECI) at the University of Oxford. He is also a Junior Research Fellow in the Tropical Forest Science group of the ECI. Chris describes his work and vision where a handheld spectrometer becomes a vital part of his laboratory on the move. “Our goal is to use leaf spectroscopy to predict leaf traits (photosynthesis, leaf chemistry, etc.). We then hope to develop these techniques to eventually use airborne remote...
The Zetasizer Nano, NanoSight Nanoparticle Tracking Analysis (NTA) and Mastersizer 2000 systems are all employed within the university’s multi-disciplinary lab. The instruments serve a wide variety of research groups working in areas as diverse as silica coating formulation through to tissue regeneration, demonstrating the value that Malvern’s robust technology brings throughout the scientific arena. “Our lab is part of The School of Engineering and...
The PURELAB® Chorus, which recently won Gold in the scientific instruments, medical devices and research equipment category of the prestigious A’ Design Award, meets all the needs of tomorrow’s pharmaceutical and biotechnology laboratories. With specific technologies to remove impurities such as RNase, DNase and bacteria as well as trace ions such as silica and boron to below detectable limits, PURELAB® Chorus can be customized to deliver water purity from...
The Andor iXon Ultra 897 EMCCD camera has been used by an international team of scientists to probe the nature of the symmetry-breaking phase transitions that began the process of creating our universe – the Kibble-Zurek mechanism. Most cosmological scientists agree that within less than a billionth of a second of the Big Bang, the young universe had to ‘decide’ which new state to adopt and, everywhere that individual areas could not...
Although most thermal cameras can produce high-contrast images showing small temperature differences, they can only do so within a defined temperature range. However when extreme temperatures appear within a scene, the hottest parts of the image will be saturated and the coldest parts will appear black or noisy, resulting in a loss of image detail and invalid temperature measurements. This is a particular problem in...