AMSBIO has introduced a unique High Throughput PARP in vivo Pharmacodynamic Assay that can be used to monitor the efficacy of poly-ADP-ribose polymerase (PARP) inhibitors on PAR formation in vivo; and to measure drug action on PARP in both in vivo and in vitro settings
In recent news, AstraZeneca reported upon how their ovarian cancer drug Lynparza™ (olaparib) is the first PARP inhibitor to be granted approval by the European Commission and the US Food and Drug Administration (FDA)**. This has led to a surge of interest in this class of drugs, which can exploit tumour DNA repair pathway deficiencies to preferentially kill cancer cells. Dr William Hadlington-Booth of AMSBIO commented "Our High Throughput PARP in vivo...
Point Of Care Testing Ltd, (POCT Ltd) is a medical diagnostics distributor of point-of-care instruments and consumables for the medical and research markets in the UK and Ireland.
POCT Ltd which also provides services to the National Independent Bowel Cancer Screening Programme, announced today the completion of a share purchase agreement to acquire 100% of the shares of Analox Instruments Ltd, (Analox) a United Kingdom based instrument and reagent manufacturing company. The transaction completed on 6th February 2015. Ian Cowie, Managing Director and CEO of Point Of Care Testing Ltd, commented...
Genevac has launched a web page that brings together the latest technological innovations and application advances, with links to reference papers, detailing how new fast, safe evaporative sample preparation techniques are benefiting metabolism and toxicology studies.
Visitors to the new web page can gain an insight into how Genevac evaporators are providing fast, safe sample preparation, free from artefact, contamination or loss, from simple concentration or drying of solvent extracts from tissue samples right through to quantitative screening of workers or athletes for the presence of a drug...
Synoptics, a world leader in the development and manufacture of innovative digital imaging systems for life science applications, is pleased to announce the group’s restructuring and change in its commercial strategy has been positively received, helping the firm’s parent company, Scientific Digital Imaging (SDI) to secure over £500,000 in new investment.
Synoptics, which celebrates 30 years in business in 2015, has been restructured to capitalise on the increasing demand for products in the North American DNA imaging and microbiology market sectors. To achieve this, Synoptics has appointed Simon Leath as VP of Sales and Marketing, at Synoptics’ North American subsidiary. Simon comes with over 16 years’ experience in sales management and sales for major international life...
Magritek, a leading provider of compact NMR and MRI instruments, report on the use of their Spinsolve Benchtop NMR spectrometer for reaction monitoring studies in the Cronin Group in the Chemistry Department of the University of Glasgow.
Professor Lee Cronin holds the Regius Chair of Chemistry at the University of Glasgow. Research in the Cronin Group is motivated by the fascination for complex chemical systems and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks. They are developing a new approach to the chemical sciences which they call Chemical Cybernetics. This combines...
GPE Scientific Ltd, a leading manufacturer and distributor of laboratory equipment and industrial and research glassware, announced today that they have officially launched a new website.
The new website offers a modern design focussing on the customer navigation and interaction across the site. The Quotation Basket function allows the customer to quickly add a wide range of products to their basket and submit the order for a finalised price. This means customers will get the best possible price direct.The website now offers four main sections, Chemistry, Life Science, Industrial Glass and Glassblowing Tools allowing customers to find a range of products suitable for their needs. The site has also been developed to include extensive product information where relevant, including technical data, videos, downloadable brochures and leaflets...
A new whitepaper from Malvern Instruments provides detailed guidance on the analytical technologies that help to accelerate oral solid dosage (OSD) product formulation to a successful conclusion.
‘Analytical techniques with a place in the oral solid dosage formulation toolkit’ reviews the regulatory and QbD framework associated with OSD formulation and demonstrates how Malvern systems can be used to generate the data required. The goal of formulation is to incorporate an identified drug substance into a successful pharmaceutical product. The regulatory framework for OSD products highlights the need to comprehensively...
Optical Surfaces Ltd. has published a new guide to provide scientists and engineers with expert advice on maintaining the performance of their aluminum coated optics.
After a time, depending on the environment in which coated optics are used, they may become contaminated with dust or stained. Dust and stains can cause scattering, and impurities on the surface of the optics can react with incident light resulting in damage to the optical coating. Starting from the premise “If it’s not dirty don’t clean it” the new guide describes a simple to follow 5-step progressive process for cleaning coated optics in a clean, low dust environment...
INTEGRA Biosciences has launched PIPETGIRL - a new pink version of its popular PIPETBOY acu 2 pipette controller.
As part of their 'PIPETGIRL – Let’s fight breast cancer together!’ campaign - INTEGRA is committing to donating Euro 10 / US $15 for every PIPETGIRL purchased during 2015 to a selection of internationally renowned cancer research institutes. Liquid handling in the millilitre range is a daily task for many labs. Unlike rubber bulb fillers, the use of serological pipettors improves the efficiency and precision of your liquid handling...
Cresset, innovative provider of computational chemistry software and services, announces that its drug discovery arm Re-Pharm Ltd has used Forge to identify novel anti-inflammatory activity for an existing drug, which is widely prescribed for other non-inflammatory conditions.
Re-Pharm was searching for drugs to be re-purposed against a new enzyme target. Using known ligands and a crystal structure as a starting point, they used Cresset’s Forge to build computational templates to match any compounds likely to be active at the new target. The results were screened and RP0217 was identified as an effective new anti-inflammatory agent. Re-Pharm has filed patents on RP0217 for a variety of disease indications...
Flame brings flexible sensing power to research and teaching labs
Ocean Optics has launched a spectrometer line that combines decades of miniature spectrometer design expertise with industry-leading manufacturing techniques. The Flame spectrometer delivers high thermal stability and low unit to unit variation without compromising the flexibility and configurability that are the hallmark of modular, miniature spectrometers. Features such as interchangeable slits, indicator LEDs and simpler device...
Fisher Scientific, part of Thermo Fisher Scientific Inc., the world leader in serving science, recently announced the winners of the Supplier Awards during its fourth European Sales Conference, held in Malta.
From January 27 - 29 2015, more than 700 delegates attended the Fisher Scientific Sales Conference at the Hilton, Malta. This was the fourth event of its kind, bringing together delegates from 21 countries. The three day event included an exhibition showcase with 63 booths featuring laboratory products from Fisher Scientific and other leading suppliers. The event culminated in a gala dinner and awards ceremony, during which the...
Courses range from beginner and intermediate to advanced levels
This year there are more than 40 new courses added in subjects such as forensics, statistics, separations, LIMS, LC/GC, mass spectrometry, nanotechnology and lab management—to name a few.Pittcon is pleased to announce the 2015 Short Courses (March 7-12). With more than 100 from which to choose, there are a wide variety of classes covering relevant topics in food science, water/wastewater, environmental, life science...
Researchers at the Centre de research du Centre hospitalier universitaire de Sherbrooke (CRCHUS) unveiled today the results of a clinical study demonstrating equivalency between cyclotron-produced technetium (Tc-99m) and that produced in a nuclear reactor.
The result of many years of research, this major clinical breakthrough will significantly affect the quality and safety of care delivered to patients. Based on the study's findings, not only are the CRCHUS's medical-imaging research positioned as leaders in this area, they are demonstrating that tomorrow's supply of medical isotopes can be produced with a promising green technology. On hand for the announcement were the Minister of...
Healthy, safe and productive people create exceptional, sustainable science
KIMTECH personal protection equipment from KIMBERLY-CLARK PROFESSIONAL* is now available for sale in bundles appropriate to standard Laboratory Biosafety Levels (BSL-) 1-3 and for use in epidemic, field based, responses. This new product strategy is just one element of Kimberly-Clark’s efforts to help laboratory managers focus on creating healthier, safer and more efficient laboratories by ensuring the purchase of...
The latest addition to the Hygiena line of rapid micro-organism tests is InSite Salmonella, which is a rapid and convenient colorimetric Salmonella species test for environmental surfaces.
Its all-in-one test format contains both the pre-enrichment and selective enrichment procedures, maintains security and minimises the risk of cross contamination. It also retains the active culture for any subsequent verification and identification tests. InSite Salmonella is a self-contained, ready-to-use swab test which contains a specialised liquid medium which changes colour when Salmonella species are present in the sample...
Researchers at University Medical Center (UMC) Utrecht are developing an innovative cancer treatment with the help of a grant from Alpe d’HuZes/Dutch Cancer Society (KWF) of nearly 300,000 euros.
The treatment involves the injection of radioactive beads into tumors, thereby enabling a very precise localized radiotherapy. Direct injection of radioactive beads may be an effective treatment of tumors that are difficult or impossible to remove surgically. This is the basic principle of medical biologist Dr. Frank Nijsen, dental surgeon Dr. Robert van Es and nuclear physician Dr. Marnix Lam of UMC Utrecht. They are working...
A new series of environmental test chambers now available from Tovatech in 4 storage capacities from 24 to 80 cubic feet feature ultrasonic humidifiers producing far smaller water particles than centrifugal humidifiers.
The ultrasonic humidifiers are placed above rather than inside storage cabinets thereby freeing space for additional test specimens. Dehumidification is handled by a separate latent coil. Both systems are operated by a programmable logic microprocessor controller. The ultrasonic humidifiers require water with low mineral content delivered at 10 to 60 psi. As a means of conserving this water an optional purification system for tap water is...
Company extends support and reach in the US for its Mosaic sample management software
Titian Software has further expanded its US operation following years of robust growth. Over the past decade, innovation and continued development of its pre-eminent sample management software, Mosaic, has secured it as the preferred choice for most of the world’s top 20 bio-pharma companies. Mosaic 6.0, released in late 2014, is optimised for the storage, processing, tracking and ordering of compounds, biologicals and reagents...
Back in 1965, Alexander Hawrylenko opened the Hawrylenko Technik in a vacant Basel kiosk. Fifty years later the name of the biotechnology specialist still incorporates his initials. By now, INFORS HT has become one of the world’s most prestigious developers and manufacturers of shakers, bioreactors and software. However, in this anniversary year 2015 the Swiss-based company is not just celebrating its own achievements but...
Hands-on learning and personalized consulting sessions for mass flow meter and controller users during the show
Alicat Scientific will bring a new learning program to Pittcon 2015, March 9 – 12, at the Ernest N. Morial Convention Center (New Orleans, Louisiana). The company’s display of mass flow and pressure instrumentation in booth number 2238 will be joined by a new series of educational and consulting sessions, Alicat U. Alicat meters and controllers measure mass flow using differential pressure, which results in a fast and accurate response. With a choice of up to...
A collaborative research project between Freeman Technology and GEA Pharma Systems is providing new insight to support the development of continuous tablet manufacturing processes, a long term goal for the pharmaceutical industry.
Both companies are investing significant resource in the project and it is expected to deliver further substantive results over the next quarter. Within the pharmaceutical industry the replacement of batch tablet production units with continuous manufacturing suites has the potential to significantly improve efficiency and reduce costs. Freeman Technology, a global leader in powder testing instrumentation, and GEA, a specialist provider...
In recent news, AstraZeneca reported upon how their ovarian cancer drug Lynparza™ (olaparib) is the first PARP inhibitor to be granted approval by the European Commission and the US Food and Drug Administration (FDA)**. This has led to a surge of interest in this class of drugs, which can exploit tumour DNA repair pathway deficiencies to preferentially kill cancer cells. Dr William Hadlington-Booth of AMSBIO commented "Our High Throughput PARP in vivo...
POCT Ltd which also provides services to the National Independent Bowel Cancer Screening Programme, announced today the completion of a share purchase agreement to acquire 100% of the shares of Analox Instruments Ltd, (Analox) a United Kingdom based instrument and reagent manufacturing company. The transaction completed on 6th February 2015. Ian Cowie, Managing Director and CEO of Point Of Care Testing Ltd, commented...
Visitors to the new web page can gain an insight into how Genevac evaporators are providing fast, safe sample preparation, free from artefact, contamination or loss, from simple concentration or drying of solvent extracts from tissue samples right through to quantitative screening of workers or athletes for the presence of a drug...
Synoptics, which celebrates 30 years in business in 2015, has been restructured to capitalise on the increasing demand for products in the North American DNA imaging and microbiology market sectors. To achieve this, Synoptics has appointed Simon Leath as VP of Sales and Marketing, at Synoptics’ North American subsidiary. Simon comes with over 16 years’ experience in sales management and sales for major international life...
Professor Lee Cronin holds the Regius Chair of Chemistry at the University of Glasgow. Research in the Cronin Group is motivated by the fascination for complex chemical systems and the desire to construct complex functional molecular architectures that are not based on biologically derived building blocks. They are developing a new approach to the chemical sciences which they call Chemical Cybernetics. This combines...
‘Analytical techniques with a place in the oral solid dosage formulation toolkit’ reviews the regulatory and QbD framework associated with OSD formulation and demonstrates how Malvern systems can be used to generate the data required. The goal of formulation is to incorporate an identified drug substance into a successful pharmaceutical product. The regulatory framework for OSD products highlights the need to comprehensively...
After a time, depending on the environment in which coated optics are used, they may become contaminated with dust or stained. Dust and stains can cause scattering, and impurities on the surface of the optics can react with incident light resulting in damage to the optical coating.
Re-Pharm was searching for drugs to be re-purposed against a new enzyme target. Using known ligands and a crystal structure as a starting point, they used Cresset’s Forge to build computational templates to match any compounds likely to be active at the new target. The results were screened and RP0217 was identified as an effective new anti-inflammatory agent. Re-Pharm has filed patents on RP0217 for a variety of disease indications...
Ocean Optics has launched a spectrometer line that combines decades of miniature spectrometer design expertise with industry-leading manufacturing techniques. The Flame spectrometer delivers high thermal stability and low unit to unit variation without compromising the flexibility and configurability that are the hallmark of modular, miniature spectrometers. Features such as interchangeable slits, indicator LEDs and simpler device...
From January 27 - 29 2015, more than 700 delegates attended the Fisher Scientific Sales Conference at the Hilton, Malta. This was the fourth event of its kind, bringing together delegates from 21 countries. The three day event included an exhibition showcase with 63 booths featuring laboratory products from Fisher Scientific and other leading suppliers. The event culminated in a gala dinner and awards ceremony, during which the...
This year there are more than 40 new courses added in subjects such as forensics, statistics, separations, LIMS, LC/GC, mass spectrometry, nanotechnology and lab management—to name a few.Pittcon is pleased to announce the 2015 Short Courses (March 7-12). With more than 100 from which to choose, there are a wide variety of classes covering relevant topics in food science, water/wastewater, environmental, life science...
The result of many years of research, this major clinical breakthrough will significantly affect the quality and safety of care delivered to patients. Based on the study's findings, not only are the CRCHUS's medical-imaging research positioned as leaders in this area, they are demonstrating that tomorrow's supply of medical isotopes can be produced with a promising green technology. On hand for the announcement were the Minister of...
KIMTECH personal protection equipment from KIMBERLY-CLARK PROFESSIONAL* is now available for sale in bundles appropriate to standard Laboratory Biosafety Levels (BSL-) 1-3 and for use in epidemic, field based, responses. This new product strategy is just one element of Kimberly-Clark’s efforts to help laboratory managers focus on creating healthier, safer and more efficient laboratories by ensuring the purchase of...
Its all-in-one test format contains both the pre-enrichment and selective enrichment procedures, maintains security and minimises the risk of cross contamination. It also retains the active culture for any subsequent verification and identification tests. InSite Salmonella is a self-contained, ready-to-use swab test which contains a specialised liquid medium which changes colour when Salmonella species are present in the sample...
The treatment involves the injection of radioactive beads into tumors, thereby enabling a very precise localized radiotherapy. Direct injection of radioactive beads may be an effective treatment of tumors that are difficult or impossible to remove surgically. This is the basic principle of medical biologist Dr. Frank Nijsen, dental surgeon Dr. Robert van Es and nuclear physician Dr. Marnix Lam of UMC Utrecht. They are working...
The ultrasonic humidifiers are placed above rather than inside storage cabinets thereby freeing space for additional test specimens. Dehumidification is handled by a separate latent coil. Both systems are operated by a programmable logic microprocessor controller. The ultrasonic humidifiers require water with low mineral content delivered at 10 to 60 psi. As a means of conserving this water an optional purification system for tap water is...
Titian Software has further expanded its US operation following years of robust growth. Over the past decade, innovation and continued development of its pre-eminent sample management software, Mosaic, has secured it as the preferred choice for most of the world’s top 20 bio-pharma companies. Mosaic 6.0, released in late 2014, is optimised for the storage, processing, tracking and ordering of compounds, biologicals and reagents...
Back in 1965, Alexander Hawrylenko opened the Hawrylenko Technik in a vacant Basel kiosk. Fifty years later the name of the biotechnology specialist still incorporates his initials. By now, INFORS HT has become one of the world’s most prestigious developers and manufacturers of shakers, bioreactors and software. However, in this anniversary year 2015 the Swiss-based company is not just celebrating its own achievements but...
Alicat Scientific will bring a new learning program to Pittcon 2015, March 9 – 12, at the Ernest N. Morial Convention Center (New Orleans, Louisiana). The company’s display of mass flow and pressure instrumentation in booth number 2238 will be joined by a new series of educational and consulting sessions, Alicat U. Alicat meters and controllers measure mass flow using differential pressure, which results in a fast and accurate response. With a choice of up to...
Both companies are investing significant resource in the project and it is expected to deliver further substantive results over the next quarter. Within the pharmaceutical industry the replacement of batch tablet production units with continuous manufacturing suites has the potential to significantly improve efficiency and reduce costs. Freeman Technology, a global leader in powder testing instrumentation, and GEA, a specialist provider...