BioTek's complete line of multi-mode microplate readers have now earned Transcreener HTS Assay certifications from BellBrook Labs.
Performance of BioTek readers including the Synergy™ Neo2 and Cytation™ 5 have been confirmed as meeting validation requirements across BellBrook's supported Fluorescence Intensity, Fluorescence Polarization and TR-FRET detection modes. Synergy Neo2 is designed for speed and ultra high performance, incorporating BioTek's patented Hybrid Technology™, with its independent optical paths that ensure uncompromised performance in all detection...
AstraZeneca today announced updated data on AZD9291 in first-line patients with epidermal growth factor receptor mutation (EGFRm) positive advanced non-small cell lung cancer (NSCLC) and previously-treated patients with EGFRm T790M mutation-positive NSCLC.
The data being presented today at the World Conference on Lung Cancer (WCLC) 2015 were from the AURA Phase I trial first-line cohort and two AURA Phase II studies. Data demonstrated that in 60 patients who received AZD9291 once daily in the first-line setting, 72% (95% confidence interval (CI) 58% to 82%) were progression free (PFS) at 12 months. Confirmed overall response rate (ORR) was 75% (95% CI 62% to 85%). The longest duration of...
MIP Diagnostics recognised at Europe’s flagship Drug Discovery conference
A technology developed at the University of Leicester, and the prime focus of Leicester spin-out company MIP Diagnostics, has been recognised as ‘most commercially viable’ at Europe’s flagship Drug Discovery event. The annual ELRIG Drug Discovery conference, held at the Telford International Centre in September, is the largest Drug Discovery conference in Europe and featured a ‘Dragons’ Den’ competition. The coveted trophy is awarded to...
Haydale, a leader in the development of enhanced graphene and nanoparticulate materials, has announced that its composites division, Haydale Composite Solutions Ltd (HCS), has signed a letter of intent to start a joint development and commercialisation agreement with Huntsman Advanced Materials (Switzerland) GmbH (Huntsman), a leading global manufacturer of epoxy, acrylic and polyurethane based polymer products.
As part of agreement Haydale will functionalise Graphene Nano Platelets (GNPs) using its proprietary HDPlas® process and add them to Huntsman's ARALDITE® resins to create a highly loaded masterbatch. Under the proposed agreement, it is anticipated that Huntsman and HCS will develop and validate the use of GNPs in ARALDITE® epoxy resins, using HCS's proprietary HDPlas® process. The ultimate objective of the collaboration will be to commercialise graphene enhanced ARALDITE® resins for...
Cleaver Scientific announces the introduction of a horizontal polyacrylamide gel electrophoresis (hPAGE) system developed in collaboration with the Kirkhouse Trust, an organisation supporting research and education in the biological sciences.
Whilst vertical systems are commonly used for polyacrylamide gel electrophoresis, this newly developed unit’s horizontal format allows for a large number of samples to be run simultaneously and combines this with the greater resolution of polyacrylamide compared with agarose. The main advantage of the system is that it is very simple to pour and cast the polyacrylamide gels which takes away some of the complexity normally associated with vertical gel casting....
Read MoreOGT Helps Genetic Scientists Explore the Medical ExomeOct 5, 2015
New whitepaper demonstrates how customisable, medically focused array designs complement NGS for clinical genetics research
Oxford Gene Technology (OGT), The Molecular Genetics Company, has been speaking to genetic scientists, Dr Tracey Lewis (Associated Regional and University Pathologists [ARUP] Laboratories) and Dr Emily Farrow (Children’s Mercy Hospital), in a new whitepaper entitled “Examining the Medical Exome”. This whitepaper describes their experiences with OGT’s CytoSure™ Medical Research Exome Array and explores how this customisable array targets a variety of genetic disorders to...
Synbiosis, a long-established, expert manufacturer of automated microbiological systems, today introduced its mASTer (measuring Antibiotic Susceptibility Testing easily and rapidly) software.
This revolutionary software saves microbiologists hours of work by reproducibly measuring zones around antibiotic discs on AST (Antibiotic Sensitivity Testing) plates and then automatically producing a bacteria’s antibiotic SIR (Susceptible, Intermediate, Resistant) category. The versatile mASTer software can be used to analyse AST plate images generated by a Synbiosis ProtoCOL 3 automated zone measurement system or from a Syngene G:BOX...
Specialised Imaging has updated and expanded its resources web page for scientists and engineers interested in or involved with ultra high-speed imaging.
The company's comprehensive range of high resolution framing cameras, trajectory trackers, still cameras, image intensifiers and accessories open the door to exciting discoveries, ground breaking research and new measurement solutions in a wide range of applications areas. Visitors to the website are given open access to an informative bibliography of research articles, application notes, video clips and still images...
Investment will accelerate development of DESKGEN genome editing software platform
Desktop Genetics Ltd (“DTG” or “the Company”), a UK bioinformatics company aiming to revolutionize the way genetic researchers work, announced today that it has secured an investment of £1.37M GBP ($2.15M USD) from a syndicate of VCs and angel investors, including IQ Capital Partners, London Business Angels, the London Co-Investment Fund, Dr Jonathan Milner (Deputy Chairman and Founder of Abcam plc), Dr Martin Murphy (CEO of Syncona Partners LLP) and Dr Darrin M Disley (CEO of Horizon Discovery Group plc). This latest round of investment will enable Desktop Genetics to
Leading molecular diagnostics firm Multiplicom N.V. today unveiled its MASTR Facility to enable the implementation of massively parallel sequencing (MPS also referred to as NGS) capabilities in clinical genetics and pathology laboratories.
The MASTR Facility will allow labs to unlock the power of personalized medicine for improved patient outcomes in a more expedited and cost effective manner. With the MASTR Facility and the current and near-term portfolio of innovative test kits, Multiplicom feels well-positioned to drive industry-leading growth. Molecular diagnostics are revolutionizing healthcare. Patients and physicians demand for genetic information is exponentially growing as the...
Research by a Northumbria academic could have a significant impact on the teaching of chemistry after he developed a radical new interpretation of a 99-year-old rule featured in all standard textbooks.
Dr Marcus Durrant, a Reader in Northumbria?s Department of Applied Sciences, realised that the treatment of hypervalency in the Lewis theory of chemical bonding was flawed while he was teaching the theory to students. The Lewis model, which was first published in 1916, features in every elementary chemistry textbook and has been taught to generations of chemists. It states that a nitrogen atom cannot have five covalent bonds, as this would...
Courses offered at beginner and intermediate levels
Pittcon is pleased to announce the 2016 Short Courses . (March 5-10). Courses, offered at beginner and intermediate levels, range from one-half day up to two-days. With more than 100 from which to choose, there are a wide variety of classes covering relevant analytical topics in food science, water/wastewater, environmental, life science, pharmaceutical to name a few. Courses for broad-based application and general lab functions include lab management...
FLIR Systems announces that the latest version of its Research IR software - ResearchIR Max version 4.2 gives users direct access to their MATLAB scripts within the software program for the first time.
This new capability allows users to access their customized MatLab® scripts directly in ResearchIR for specially-tailored thermal image analysis and processing tasks. Many useful MatLab functions can now be directly accessed from within ResearchIR. Combining FLIR thermal and other cameras with MATLAB provides you with a flexible environment to explore algorithms for multi-sensor systems. To demonstrate the powerful utility of this new capability...
BRD4 inhibitors are among the most promising new agents in cancer therapy that are currently evaluated in clinical trials.
In a study published in NATURE today, a team of researchers at the Research Institute of Molecular Pathology (IMP) and Boehringer Ingelheim in Vienna reveals how leukemia cells can evade the deadly effects of BRD4 inhibition. Understanding this adaptation process could aid the development of sequential therapies to outsmart resistant leukemias. Over the past years, scientists have drawn an almost complete map of mutations in cancer. However, translating complex genetic knowledge into effective...
A new short and engaging SimpleShow’ format video from INTEGRA introduces and explains the unique features and benefits of their Multichannel Pipette Reagent Reservoirs.
The video features the continuing story of animated lab heroes Mason and Mary. Watching this funny video you will learn about how INTEGRA 10ml, 25ml and 100ml Multichannel reagent reservoirs are designed to nest inside each other, making it possible to get twice as many reservoirs in half the space of other products, reducing inventory space requirements and shipping costs. Unlike traditional reservoirs that have hard to see graduations moulded...
Markes International (Llantrisant, UK) has announced that it has opened a second office in the USA, near Sacramento, California.
This office will provide more local support to West Coast customers, and following the opening of Markes’ Cincinnati office in 2012, reflects the extent to which the company’s business is growing within the USA. Ken Umbarger, Markes’ VP of Sales & Service for the Americas, said “A large part of our business and potential business is in California, so having a West Coast presence for sales and service means we can assist local customers much...
Greenovation Biotech GmbH announced today that it has received approval to begin a phase I clinical trial in Europe for its first drug candidate moss-aGal (agalsidase) from Germany's regulatory authority, the Federal Institute for Drugs and Medical Devices (BfArM).
Moss-aGal, a recombinant form of human alpha galactosidase, has been developed by Greenovation as an enzyme replacement therapy (ERT) for patients with the genetic lysosomal storage disorder Fabry disease. Greenovation has used its proprietary BryoTechnology, an innovative moss gene expression system, to express the moss-aGal protein in Physcomitrella patens. The technology attaches mannose molecules to the surface of the moss aGal protein...
High purity water experts Veolia Water Technologies has completed installation of laboratory water purification systems at the National Institute for Health Research’s National Biosample Centre in Milton Keynes.
The £24m Centre, which is managed by UK Biocentre on behalf of the University of Oxford and the NIHR, has the capacity to store up to 20 million biological samples and provides laboratory facilities for research into treatments for conditions such as dementia and diabetes. The NBC facility has several laboratories, each requiring two grades of water: Type II water for general laboratory applications such as; media preparation and buffer solutions, and ultrapure Type I+ water for critical processes...
BMG LABTECH showcases its wide range of microplate reader at the Biotechnica in Hannover.
Visitors of booth D05 have the possibility to see readers and accessories for use in life science, drug discovery and other research areas. BMG LABTECH shows its multimode microplate reader CLARIOstar® with new Atmospheric Control Unit (ACU). The CLARIOstar® multimode microplate reader is equipped with BMG LABTECH’s unique LVF monochromatorTM technology, filters, and an UV/Vis spectrometer. The triple technology offers high...
The proportion of cancers diagnosed as a result of emergency presentation at hospital has decreased.
At the same time, the proportion of cancers diagnosed through urgent GP referral with a suspicion of cancer (known as the two week wait) has increased. Presented at the second day of the PHE Conference 2015, these results are taken from the updated Routes to Diagnosis data, covering patients diagnosed with cancer from 2006 to 2013, with 2011-2013 being published for the first time. These new preliminary figures show the proportion of patients diagnosed...
Asynt reports on how chromatography specialists - Reach Separations Ltd. are benefiting from the installation of an onsite nitrogen generator at their laboratories in Nottingham, UK.
Reach Separations specialises in chiral chromatography for the analysis and purification of small molecules. Using state-of-the-art HPLC and SFC instrumentation, Reach Separations offer screening, method development and purification for chiral and achiral molecules across the pharmaceutical, agrochemical and fine chemical sectors. To further enhance the speed and efficiency of their contract research service, Reach Separations recently invested in an Asynt nitrogen generator to replace their use of...
Maven Capital Partners (“Maven”) and Albion Ventures LLP (“Albion”), two of the largest independent venture capital investors in the UK, today jointly announce the successful sale of their investment in Lab M Holdings, a developer, manufacturer and supplier of microbiological culture media and diagnostic systems, to Neogen Corporation.
Lancashire-based Lab M is a leading provider of microbial testing and diagnostic products servicing the global food, water, industrial and clinical testing markets. Employing some 35 staff at its accredited facility in Heywood, Greater Manchester, the company’s widerange of dehydrated culture media is routinely used in microbiology laboratories around the world for food industry testing. The original Lab M investment was made by Quester VCT Plc and...
Performance of BioTek readers including the Synergy™ Neo2 and Cytation™ 5 have been confirmed as meeting validation requirements across BellBrook's supported Fluorescence Intensity, Fluorescence Polarization and TR-FRET detection modes. Synergy Neo2 is designed for speed and ultra high performance, incorporating BioTek's patented Hybrid Technology™, with its independent optical paths that ensure uncompromised performance in all detection...
The data being presented today at the World Conference on Lung Cancer (WCLC) 2015 were from the AURA Phase I trial first-line cohort and two AURA Phase II studies. Data demonstrated that in 60 patients who received AZD9291 once daily in the first-line setting, 72% (95% confidence interval (CI) 58% to 82%) were progression free (PFS) at 12 months. Confirmed overall response rate (ORR) was 75% (95% CI 62% to 85%). The longest duration of...
A technology developed at the University of Leicester, and the prime focus of Leicester spin-out company MIP Diagnostics, has been recognised as ‘most commercially viable’ at Europe’s flagship Drug Discovery event. The annual ELRIG Drug Discovery conference, held at the Telford International Centre in September, is the largest Drug Discovery conference in Europe and featured a ‘Dragons’ Den’ competition. The coveted trophy is awarded to...
As part of agreement Haydale will functionalise Graphene Nano Platelets (GNPs) using its proprietary HDPlas® process and add them to Huntsman's ARALDITE® resins to create a highly loaded masterbatch. Under the proposed agreement, it is anticipated that Huntsman and HCS will develop and validate the use of GNPs in ARALDITE® epoxy resins, using HCS's proprietary HDPlas® process. The ultimate objective of the collaboration will be to commercialise graphene enhanced ARALDITE® resins for...
Whilst vertical systems are commonly used for polyacrylamide gel electrophoresis, this newly developed unit’s horizontal format allows for a large number of samples to be run simultaneously and combines this with the greater resolution of polyacrylamide compared with agarose. The main advantage of the system is that it is very simple to pour and cast the polyacrylamide gels which takes away some of the complexity normally associated with vertical gel casting....
Oxford Gene Technology (OGT), The Molecular Genetics Company, has been speaking to genetic scientists, Dr Tracey Lewis (Associated Regional and University Pathologists [ARUP] Laboratories) and Dr Emily Farrow (Children’s Mercy Hospital), in a new whitepaper entitled “Examining the Medical Exome”. This whitepaper describes their experiences with OGT’s CytoSure™ Medical Research Exome Array and explores how this customisable array targets a variety of genetic disorders to...
This revolutionary software saves microbiologists hours of work by reproducibly measuring zones around antibiotic discs on AST (Antibiotic Sensitivity Testing) plates and then automatically producing a bacteria’s antibiotic SIR (Susceptible, Intermediate, Resistant) category. The versatile mASTer software can be used to analyse AST plate images generated by a Synbiosis ProtoCOL 3 automated zone measurement system or from a Syngene G:BOX...
The company's comprehensive range of high resolution framing cameras, trajectory trackers, still cameras, image intensifiers and accessories open the door to exciting discoveries, ground breaking research and new measurement solutions in a wide range of applications areas. Visitors to the website are given open access to an informative bibliography of research articles, application notes, video clips and still images...
Desktop Genetics Ltd (“DTG” or “the Company”), a UK bioinformatics company aiming to revolutionize the way genetic researchers work, announced today that it has secured an investment of £1.37M GBP ($2.15M USD) from a syndicate of VCs and angel investors, including IQ Capital Partners, London Business Angels, the London Co-Investment Fund, Dr Jonathan Milner (Deputy Chairman and Founder of Abcam plc), Dr Martin Murphy (CEO of Syncona Partners LLP) and Dr Darrin M Disley (CEO of Horizon Discovery Group plc). This latest round of investment will enable Desktop Genetics to
The MASTR Facility will allow labs to unlock the power of personalized medicine for improved patient outcomes in a more expedited and cost effective manner. With the MASTR Facility and the current and near-term portfolio of innovative test kits, Multiplicom feels well-positioned to drive industry-leading growth. Molecular diagnostics are revolutionizing healthcare. Patients and physicians demand for genetic information is exponentially growing as the...
Dr Marcus Durrant, a Reader in Northumbria?s Department of Applied Sciences, realised that the treatment of hypervalency in the Lewis theory of chemical bonding was flawed while he was teaching the theory to students. The Lewis model, which was first published in 1916, features in every elementary chemistry textbook and has been taught to generations of chemists. It states that a nitrogen atom cannot have five covalent bonds, as this would...
Pittcon is pleased to announce the 2016 Short Courses . (March 5-10). Courses, offered at beginner and intermediate levels, range from one-half day up to two-days. With more than 100 from which to choose, there are a wide variety of classes covering relevant analytical topics in food science, water/wastewater, environmental, life science, pharmaceutical to name a few. Courses for broad-based application and general lab functions include lab management...
This new capability allows users to access their customized MatLab® scripts directly in ResearchIR for specially-tailored thermal image analysis and processing tasks. Many useful MatLab functions can now be directly accessed from within ResearchIR. Combining FLIR thermal and other cameras with MATLAB provides you with a flexible environment to explore algorithms for multi-sensor systems. To demonstrate the powerful utility of this new capability...
In a study published in NATURE today, a team of researchers at the Research Institute of Molecular Pathology (IMP) and Boehringer Ingelheim in Vienna reveals how leukemia cells can evade the deadly effects of BRD4 inhibition. Understanding this adaptation process could aid the development of sequential therapies to outsmart resistant leukemias. Over the past years, scientists have drawn an almost complete map of mutations in cancer. However, translating complex genetic knowledge into effective...
The video features the continuing story of animated lab heroes Mason and Mary. Watching this funny video you will learn about how INTEGRA 10ml, 25ml and 100ml Multichannel reagent reservoirs are designed to nest inside each other, making it possible to get twice as many reservoirs in half the space of other products, reducing inventory space requirements and shipping costs. Unlike traditional reservoirs that have hard to see graduations moulded...
This office will provide more local support to West Coast customers, and following the opening of Markes’ Cincinnati office in 2012, reflects the extent to which the company’s business is growing within the USA. Ken Umbarger, Markes’ VP of Sales & Service for the Americas, said “A large part of our business and potential business is in California, so having a West Coast presence for sales and service means we can assist local customers much...
Moss-aGal, a recombinant form of human alpha galactosidase, has been developed by Greenovation as an enzyme replacement therapy (ERT) for patients with the genetic lysosomal storage disorder Fabry disease. Greenovation has used its proprietary BryoTechnology, an innovative moss gene expression system, to express the moss-aGal protein in Physcomitrella patens. The technology attaches mannose molecules to the surface of the moss aGal protein...
The £24m Centre, which is managed by UK Biocentre on behalf of the University of Oxford and the NIHR, has the capacity to store up to 20 million biological samples and provides laboratory facilities for research into treatments for conditions such as dementia and diabetes. The NBC facility has several laboratories, each requiring two grades of water: Type II water for general laboratory applications such as; media preparation and buffer solutions, and ultrapure Type I+ water for critical processes...
Visitors of booth D05 have the possibility to see readers and accessories for use in life science, drug discovery and other research areas. BMG LABTECH shows its multimode microplate reader CLARIOstar® with new Atmospheric Control Unit (ACU). The CLARIOstar® multimode microplate reader is equipped with BMG LABTECH’s unique LVF monochromatorTM technology, filters, and an UV/Vis spectrometer. The triple technology offers high...
At the same time, the proportion of cancers diagnosed through urgent GP referral with a suspicion of cancer (known as the two week wait) has increased. Presented at the second day of the PHE Conference 2015, these results are taken from the updated Routes to Diagnosis data, covering patients diagnosed with cancer from 2006 to 2013, with 2011-2013 being published for the first time. These new preliminary figures show the proportion of patients diagnosed...
Reach Separations specialises in chiral chromatography for the analysis and purification of small molecules. Using state-of-the-art HPLC and SFC instrumentation, Reach Separations offer screening, method development and purification for chiral and achiral molecules across the pharmaceutical, agrochemical and fine chemical sectors. To further enhance the speed and efficiency of their contract research service, Reach Separations recently invested in an Asynt nitrogen generator to replace their use of...
Lancashire-based Lab M is a leading provider of microbial testing and diagnostic products servicing the global food, water, industrial and clinical testing markets. Employing some 35 staff at its accredited facility in Heywood, Greater Manchester, the company’s widerange of dehydrated culture media is routinely used in microbiology laboratories around the world for food industry testing. The original Lab M investment was made by Quester VCT Plc and...