Scientists have identified a mutation that gives cancer cells resistance to the breakthrough cancer treatment olaparib and other PARP inhibitors. The study findings could help predict which patients will develop resistance to PARP inhibitors and allow doctors to alter treatment at the earliest possible opportunity. A team at The Institute of Cancer Research, London, used gene editing to identify a specific mutation in the PARP1 protein that prevents PARP inhibitors from working.
Investment to fund expansion of operations and progression of drug target pipeline. PhoreMost, the UK-based biopharmaceutical company dedicated to drugging ‘undruggable’ disease targets, has announced it has completed an £11m ($15m) Series-A investment round. The investment will be used to expand operations on the Babraham Research Campus and progress several novel drug targets from...
Science World, the Fisher Scientific Laboratory Experience, made its successful launch in Spain at the IFEMA North Convention Centre in Madrid. The event, hosted by Thermo Fisher Scientific, showcased the latest in laboratory innovations available through Fisher Scientific. Thousands of products were available for attendees to experience, making it an ideal event for anyone working in or around a laboratory.
Save the date for the UK’s only lab-dedicated exhibition showcase! Lab Innovations, the UK’s only trade show dedicated to the laboratory industry, returns to the NEC, Birmingham, on 31 October & 1 November 2018. Free-to-attend and supported by some of the UK’s top scientific institutions, Lab Innovations is the nation’s largest gathering of laboratory professionals, growing year on year, with almost a third more...
Greiner Bio-One North America, Inc. has acquired 3D Cell Culture Technology previously owned by Nano 3D Biosciences, Inc. As an international distributor of these products since 2016, Greiner Bio-One has now taken the initiative to become a premier provider of this technology worldwide. Magnetic 3D cell culture has become a disruptive technology in the research...
Landmark paper sets out ‘unified theory’ for cause of childhood leukaemia – and finds it is likely to be preventable. Disease develops in two steps: a mutation before birth, then further genetic change after birth triggered by infection. Evidence challenges 100 years of controversy around other possible environmental ‘causes’ of the disease....
JULABO celebrated the official opening of the new modern company building in Stamford / Lincolnshire. General Manager Markus Juchheim welcomed representatives from trade, construction management and finances as well as the project team to the opening celebration. After a champagne reception, guests and JULABO employees toured the company, followed by a meal in relaxed atmosphere....
TTP Plc (TTP), a leading independent technology and product development company, and Camena Bioscience, a developer of pioneering technology that profiles small molecules, such as metabolites, nutrients or medicines in liquid samples, announced today that they are collaborating to develop an instrument to monitor the health of cell cultures. The new instrument will be used in biologic medicine manufacturing, and will be developed by...
The University of Birmingham has won funding for a powerful new piece of technology called a spectrometer which will allow scientists to better gain insights into the molecular basis of human health – including the progression of cancer and infectious diseases. The spectrometer, which will operate at a strength around 500,000 times stronger than the earth’s magnetic field, will be...
The only modular isolator to offer built in Bioquell Hydrogen Peroxide Vapor technology for rapid bio-decontamination, reduced risk and major cost benefits. One of the leading global experts in reducing the risk of bio-contamination in the Life Science market – highlighted the suitability of its state-of-the-art Bioquell Qube aseptic workstation for the rapidly emerging CAR-T and gene and cell therapy sector. The isolator, which can be customised to suit the individual needs of cell therapy...
JEOL, a leading developer and manufacturer of NMR technology, unveiled new NMR probes and NMR software technologies at the 59th Experimental Nuclear Magnetic Resonance Conference (ENC) in Orlando, Florida. As a major sponsor of this year’s conference, JEOL also hosted a technical seminar that included talks by leading researchers from the Osaka University Institute for Protein Research...
Protagen AG has announced the start of a collaboration with the University of California, San Francisco (UCSF) to utilize Protagen’s SeroTag® technology to investigate the immuno-profiling of prostate cancer patients treated with checkpoint inhibitors and therapeutic vaccines. Cancer immunotherapies can be very powerful and provide novel opportunities for the treatment of cancer....
Acquisition strengthens growing network’s resources to service pharmaceutical and research partners globally. LMC Manna Research – the largest network of fully-owned and integrated clinical research sites in Canada providing Phase I-IV clinical trial services has announced the acquisition of leading Montreal-based research centre Omnispec Clinical Research. Having contributed to the development of more than 60 drugs, Omnispec adds greater...
Measuring grip strength – a clinical test that is both cheap and easy to perform – could be an important way to identify people who are at high risk for a wide range of diseases. New research, led by the University of Glasgow’s Institute of Cardiovascular and Medical Sciences and published in the BMJ, found that lower grip strength was strongly associated with a wide range of poorer health outcomes, including...
The latest imaging technologies, which are instrumental to revealing structural and functional information for biological, material and geosciences research, were showcased at a global research event. The University of Portsmouth, in collaboration with Zeiss, hosted a ‘Correlative Microscopy Workshop’. This workshop consisted of scientific talks in the morning and instrument demos in the afternoon, covering biological, materials and geosciences topics....
Once again, Systec GmbH, the leading manufacturer of autoclaves, including laboratory autoclaves, media preparators, and dispensing devices for liquid media and microbiological culture media, presents the highlights of its comprehensive product range at the ACHEMA in Frankfurt, from 11th until 15th June. The company’s trusted line of laboratory autoclaves, suitable for almost any application, is based around the Systec H-Series, which includes large, standing horizontal autoclaves and double-door pass-through autoclaves
Antibodies Used to Support Research into the Treatment of Ulcerative Colitis and Crohn’s Disease. HBio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, has announced the release of a range of anti-vedolizumab antibodies. Vedolizumab (Entyvio) is a monoclonal antibody that is used to treat ulcerative colitis (inflammatory bowel disease) and Crohn’s disease...
Dolomite Bio, a leading provider of high throughput single cell technology, and Partek Incorporated, a recognized leader in the development of powerful genomic data analysis tools – today announced a collaboration to combine Partek’s single cell data analysis capabilities with Dolomite Bio’s microfluidic droplet-based single cell technology. Single cell data analysis enables researchers to gain useful insights into the diversity and state of single cells in a particular sample...
Algenuity, a leader in algal biology and industrial biotechnology, is delighted to welcome Dr Alex Pudney to the team as Chief Scientific Officer. Alex brings a wealth of experience to the role, having previously worked in both research and start-ups tackling issues of sustainability and renewable alternatives to petrochemicals. His skills in strain engineering, and expertise in directed evolution and design of experiments, are already proving invaluable to the Algenuity team....
Huber Kältemaschinenbau presents new temperature control solutions for research, laboratories and production in Frankfurt. At ACHEMA 2018, Huber will be showcasing new solutions and further developments in temperature control from -125 °C to +425 °C for research laboratories and process industry. Visitors can expect an interesting cross-section of the Huber product range at the completely new designed 208 m² booth...
In May 2016, Hichrom acquired the worldwide exclusive rights to manufacture the Alltima®, Alltima® HP, Prevail™, Apollo™, Allsep®, Apex™, and Genesis™ HPLC column ranges from Grace. Additionally, Vydac® HPLC columns are now available exclusively from Hichrom. Hichrom manufactures these column ranges to the same exacting manufacturing protocols and to identical technical specifications previously used by Grace/Alltech in manufacturing facilities accredited to both ISO9001 and ISO14001 standards....
A new case study from Autoscribe Informatics discusses the useof the Matrix LIMS (Laboratory Information Management System) in the Cereal, Milling and Baking Science Laboratory at Allied Technical Centre (ATC). It illustrates how a flexible, configurable LIMS can be adapted by the users themselves to meet changing requirements....