Oligonucleotides must be of high purity when used within molecular biology applications such as qPCR, next-generation sequencing, and microarray analysis. In the following application note, Gilson explore how the VERITY® Oligo Purification System, configured with automated preparative and analytical HPLC capabilities, can be a solution to isolate, analyze, and desalt reagent-grade oligonucleotides in one continuous run...
LEEUWENHOEK’S THIRD CENTURY - Revealing the Sights of the Seventeenth Century by Brian J Ford Hon FRMS, Hon FLS. There was much excitement around the world when I revealed one of the most extraordinary revelations of my entire academic life – the original microscope specimens, prepared by Antony van Leeuwenhoek in the 1600s, had survived intact. They lay secure in folded paper envelopes hidden among his letters to London, and carefully preserved at the Royal Society...
PacBio, a leading developer of high-quality, highly accurate sequencing solutions and GeneDx, a leader in delivering improved health outcomes through genomic and clinical insights, have announced a research collaboration with the University of Washington to study the capabilities of HiFi long-read whole genome sequencing (WGS) to increase diagnostic rates in pediatric patients with genetic conditions...
CloudLIMS, a leading ISO 9001:2015 certified and SOC 2 compliant company offering a secure, configurable, high-quality Laboratory Information Management System (LIMS), is pleased to announce a complimentary webinar titled “From Data Management to Quality Assurance: Exploring the Integration of Healthcare LIMS Software and ISO 15189 in Diagnostic Labs” on August 22, 2023, at 9 A.M. PDT (5 P.M. BST). The webinar will be presented by Martha Hernández, Scientist...
Thermo Fisher Scientific recently announced the expansion of Services Central, its online service platform, for customers across the United States and Western Europe. Customers can now use the platform to access service information on demand and expedite the support process for their analytical instruments and laboratory equipment. With Services Central, customers can save time and more efficiently manage their instruments and equipment...
PacBio a leading developer of high-quality, highly accurate sequencing solutions, announced that customer shipments of Onso short-read sequencing instruments will commence today. As previously announced, the Onso system is designed to provide extraordinary accuracy through its novel sequencing by binding (SBB) chemistry in a user-friendly and flexible benchtop platform. "When we announced the Onso platform last year, I knew it would be a game changer for genomics," said Christian Henry, President and Chief Executive Officer of PacBio...
BioServe Space Technologies at the University of Colorado Boulder and Sierra Space have developed a pathfinder spaceflight investigation designed to expand hematopoietic stem cells (stem cells that develop into blood cells) derived from umbilical cord blood in microgravity. The project is being done in partnership with researchers from the Mayo Clinic (Jacksonville, Florida) and ClinImmune on the University of Colorado Medical Campus...
When working within a life sciences laboratory one of the most important assets is your samples. This is why it is imperative to preserve, store and retrieve samples while maintaining their integrity. With any large store or “library” of compounds or other samples, being able to easily retrieve a specified sub-set of samples is key to any research workflow - this is the so-called “pick list.” A new technical paper from Ziath describes how their Mirage 2D tube rack reader and Mohawk semi-automated tube picker...
To enhance the reproducibility of flow chemistry scale-up - precise control of mixing and temperature in highly exothermic or rapid reactions in particular is essential. The expanding range of Glass Static Mixer (GSM) chip reactor blocks from Uniqsis produce an efficient, turbulent mixed reagent stream for flow chemistry reactions that is not diffusion dependent. Available in sizes from 270µl to 20 ml, the Uniqsis range of high-quality GSM chips can be used to perform reactions from -80°C to over 150°C...
A new study demonstrates how the combination of DNA-encoded libraries (DELs) and NanoBRET Target Engagement technology can accelerate early-stage drug discovery. Reported in Cell Chemical Biology, researchers from Promega Corporation and WuXi AppTec generated new chemical probes from molecules identified through a DEL screen. This research opens new opportunities to develop novel NanoBRET Target Engagement Assays aimed at many understudied classes of proteins, rapidly accelerating “hit to lead” efforts in identifying new potential therapeutics...
A major milestone towards the redefinition of the second has been achieved by scientists at the National Physical Laboratory (NPL) with the first inclusion of a UK optical frequency standard (NPL-Sr1) in the determination of International Atomic Time (TAI). Calculating TAI is a major resource for determining Coordinated Universal Time (UTC), the shared international reference time scale that countries worldwide use to synchronise clocks...
Elsevier, a global leader in scientific information and data analytics, releases an alpha version of Scopus AI for researcher testing – a next generation tool that combines generative AI with Scopus' trusted content and data to help researchers get deeper insights faster, support collaboration and societal impact of research. For more than a decade, Elsevier has been using AI and machine learning technologies responsibly in its products combined with its unparalleled peer-reviewed content, extensive data sets, and sophisticated analytics...
Evident unveiled the winners of its fourth Global Image of the Year Scientific Light Microscopy Award, an annual competition that recognizes the best in scientific imaging worldwide. The winners were selected from 640 images submitted from 38 countries around the world. Laurent Formery from the United States was selected as the global winner for his stunning image of the nervous system of a juvenile sea star (Patiria miniata)...
California Seed and Plant (CSP) Labs, a leading private plant pathology and genetics testing laboratory in California, is using VIAFLO 96 and VIAFLO 384 handheld electronic pipettes from INTEGRA Biosciences to streamline its nucleic acid extraction and sample processing workflows. These 24, 96 and 384 channel pipettes are used to help assess seed, plant and soil health with greater efficiency and reproducibility, supporting innovations in the agricultural industry to keep up with rising global food demands...
Titian Software LTD, the global leader in life sciences sample management software, and the life science company Evotec have signed a 3-year agreement to expand their collaboration around Titian Software’s Mosaic Sample Management Platform. Mosaic forms part of Evotec’s plans to expand and harmonise sample management throughout the organisation, underpinning its expanding services...
Revvity has announced that its Revvity Signals Software business has entered into a strategic relationship with Scitara – a leading global provider of cloud-based solutions for the scientific industry. Together, the companies will transform the way R&D teams work across the biotech, pharmaceutical and chemical industries with technology that accelerates digital transformation in the lab environment...
The automation of laboratories used to be considered very costly and not very flexible, because the workflows are very complex and amounts of data are constantly increasing. Yet, as chemical and pharmaceutical industry product lifecycles become shorter and shorter, the need for digitalization has become urgent. In this article, Christof Franzke, Senior Technical Consultant Key Accounts at COPA-DATA, the industrial software specialist, explains the vital role of the zenon platform in the roll-out of modularization and digitalization in laboratories...
Accelerated Technology Laboratories, Inc. (ATL), a leader in Laboratory Information Management Systems (LIMS), continues the 2023 LIMS Webcast Series on Wednesday, August 9, with Why We Love LIMS: ATL Customers Tell Their LIMS Success Stories. Feedback from webcast attendees has always been very positive when we invite ATL LIMS clients to share their views on how a LIMS has become an essential component of their laboratory operations...
Scientists and engineers at the National Physical Laboratory (NPL)are working with colleagues at the Science and Technology Facilities Council’s (STFC) RAL Space to deliver a small satellite calibration facility. The new facility is being designed, manufactured and tested at NPL’s Teddington site in south-west London and will be located at Harwell Campus. It will draw on expertise from NPL’s STAR-cc-OGSE facility, which provides innovative solutions for calibrating scientific instruments on satellites before their launch into space...
Merck has announced the expansion of its facility in Lenexa, Kansas, USA adding 9,100 sq m2 of lab space and production capability to manufacture cell culture media. Lenexa, Kansas, USA facility becomes company’s largest dry powder cell culture media facility and Center of Excellence in North America. The company’s strategic investments to expand capacity with the new dry powder media manufacturing lines in existing production facilities in the Lenexa, Kansas...
A £5 million award from the UK Space Agency will allow Northumbria University to take forward world-leading research to build a new satellite communications system, setting the scene for Northumbria to launch the UK’s first university-led multi-satellite space mission. The funding announcement made today allow the University to move forward with its prototype work on this new laser-based system, which has the potential to transform the satellite communications industry...
Eremid® Genomic Services, LLC (“Eremid”) announces a significant expansion of its in-house sequencing capabilities with the installation of PacBio’s latest HiFi sequencing platform, the Revio. This powerful new sequencing system is the newest addition to Eremid’s suite of high-end genomics tools, and affirms the Company’s commitment to supporting larger scale and more diverse genomics projects following a $3M venture capital investment...