A new study could lead to improved decision making in assigning treatments for children with the aggressive cancer rhabdomyosarcoma after revealing key genetic changes underlying development of the disease. In the largest and most comprehensive study of rhabdomyosarcoma to date, scientists found that specific genetic changes in tumours are linked to aggressiveness, early age of onset and location in the body....
Sinocompound Catalysts Co., Ltd has launched a new video series sharing its specialist catalyst expertise adding to its bank of educational materials. Titled ‘The essentials in a synthetic chemist’s toolbox’, the series was the idea and work of technical advisor, Dr Carin Seechurn. As a global provider of advanced homogeneous catalysts and ligands for pharmaceutical and fine chemical applications, Sinocompound is ideally placed to guide scientists through some of the challenges they may need to navigate...
Waters and The Bioprocessing Technology Institute (BTI) are engaging in data analytics research meant to eliminate a major bottleneck in the characterization of biopharmaceuticals, namely the identification and quantitation of complex biomolecules such as released N- and O- glycans and metabolites that influence therapeutic function. Isomerism of both glycans and metabolites is particularly troublesome and can be tackled using Waters’ advanced instruments....
SGD Pharma announces that its 20ml EasyLyo molded glass Type I vials are now available Ready-to-Use (RTU) in SG EZ-fill? Nest & Tub – an industry-recognized state-of-the-art secondary packaging format. Increased demand for parenteral drugs generated by the Covid-19 pandemic has resulted in additional pressures being placed on biopharmaceutical companies to accelerate their time-to-market....
Win 1 of 20 pipette kits to become a highly productive, low waste lab. Each kit includes: One VIAFLO electronic multichannel pipette of your choice, One case of ECO Rack GripTips (10 racks, sterile, filter), One reusable PopTop Base for use with ECO Racks and One single pipette charging stand...
Scientific Laboratory Supplies (SLS) has recently been accredited as a Living Wage Employer. The Living Wage commitment will see everyone working at SLS receive a minimum hourly wage of £9.50 in the UK, or £10.85 in London. Both rates are significantly higher than the government minimum for over 25s, which currently stands at £8.72 per hour...
The Government Chemist (GC), hosted at LGC, has published the results of a recent international ring trial on the determination of cannabidiol (CBD) - an uncontrolled cannabinoid- and controlled cannabinoids in consumer products such as food and cosmetics. Consumer CBD products have entered the UK market rapidly in a variety of forms, including food and cosmetics. CBD when used as an ingredient in food or cosmetic products must currently be free from controlled cannabinoids....
A shortlist of eye-catching images and videos has been drawn up for the RMS Scientific Imaging Competition – featuring as part of mmc2021. As a ‘sneak preview’, the RMS has put together a collage of all the shortlisted entries across the different categories (excluding video entries) ahead of mmc2021. The images and videos will be uploaded to an online gallery available to view from the start of the event...
AMSBIO invite the global research community to the 2021 annual meeting of the ISSCR, the leading professional organization of stem cell scientists, to discover how iPSCs and organoids can be used in COVID-19 drug discovery research. At this virtual meeting - Dr. Kazuo Takayama from the renowned Center for iPS Cell Research and application (CiRA) at Kyoto University will be giving a unique insight into his recent pioneering research...
The Maulide Group at the University of Vienna (Austria) describe how a devastating water leak in a nearby chemistry laboratory prompted them to search for alternative, water-free, options to Liebig condensers for refluxing. The group teamed up with Green Labs Austria to see if they could provide and share a more sustainable solution to water cooled refluxing in the lab....
The moisture determination of liquid soap is essential to ensure a product of the highest quality. If the moisture content is too high or too low, this can result in a low quality product and wastage can occur. In this application note we determine the moisture of liquid soap using Precisa’s XM60/EM120 Halogen moisture analyser...
In 2021, Eppendorf AG, the Hamburg life sciences company, is presenting its highly prestigious research prize for the 26th time. The independent Eppendorf Award Jury chaired by Prof. Reinhard Jahn announced Dr. Tanmay Bharat, Sir William Dunn School of Pathology, University of Oxford, United Kingdom as the winner of the Eppendorf Award for European Investigators 2021....
HORIBA announces its participation in a new consortium formed to accelerate the development of process analytical technologies (PAT) in cell and gene therapy manufacturing. HORIBA’s new A-TEEM™ Molecular Fingerprinting technology has shown great promise for fast QC/QA of complex biological systems and is a core technology being assessed for reducing batch failures and manufacturing costs, to enable faster time to market....
108Labs, a biotechnology and software company with a mission to invent disruptive cellular agriculture projects, has announced their focus on building and programming the world’s first autonomous Cellufacturing® facility and artificial intelligence platform for the production of cell-cultured human milk, in the birthplace of biosynthetic human milk, Hillsborough, North Carolina....
Binding Site is pleased to announce that the ground-breaking iStopMM (Iceland Screens, Treats or Prevents Multiple Myeloma) study has reached an important milestone, with the publication of a paper outlining the design and recruitment of this population-based screening study. The large-scale study – which includes over 80,000 individuals, more than half of the eligible population of Iceland...
Leading Drug Discovery Contract Research Organisation Sygnature Discovery has announced the set-up of a state-of-the-art Early Candidate Developability Screening Group. Located at its headquarters in Nottingham, UK, the new service line will expand on the company’s offerings to customers by bridging into formal preclinical drug development and paving the way for clinical trials...
Scientists have identified a new class of targeted cancer drugs that offer the potential to treat patients whose tumours have faulty copies of the BRCA cancer genes. The drugs, known as POLQ inhibitors, specifically kill cancer cells with mutations in the BRCA genes while leaving healthy cells unharmed. And crucially, they can kill cancer cells that have become resistant to PARP inhibitors – an existing treatment for patients with BRCA mutations....
As the COVID-19 pandemic continues, the worldwide search for an effective treatment is still ongoing. Remdesivir and GS-441524 are antiviral drugs that have been examined for the treatment of COVID-19 caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Remdesivir is a nucleotide analogue inhibitor that can inhibit the replication of animal and human coronaviruses...
Australian National Phenome Centre Integrates Quantitative NMR and MS Assay Platform for Risk Assessment and Longitudinal Monitoring of Post-Acute COVID-19 Syndrome (PACS). A clinical research collaboration on COVID-19 pheno-conversion and subsequent pheno-reversion has discovered transient and persistent systemic changes of the molecular signatures in patient blood samples three months after the acute COVID-19 disease phase...
A new white paper, written by scientists at Liverpool ChiroChem (LCC), describes how the Asynt Illumin8 parallel photoreactor is being used to synthesise a range of new 2-Aryl N-Heterocycles. The discovery of a novel enantioselective synthetic pathway for reduction of pyridines to the corresponding chiral piperidines led to the formation of LCC in 2014. Since inception, LCC have enhanced their expertise enabling them to provide leading scientific organisations with access to chirally-pure compounds that play their part in small molecule drug discovery....
Whilst commonly used air displacement pipettes are highly accurate for most pipetting applications, their performance is adversely affected by the physical properties of the solutions handled, such as viscosity, volatility, surface tension and temperature. However, positive displacement pipettes like Gilson's ergonomic MICROMAN® E and Capillary Pistons (CPs) work differently, and volume delivery is unaffected by the nature of the sample...
The Native Antigen Company, part of LGC Clinical Diagnostics and one of the world’s leading suppliers of reagents that enables research into diagnostics and vaccines for emerging and endemic infectious diseases, won ‘The Best COVID-19 Responder’ at OBN 2020 Awards. The award recognises the Company’s outstanding contribution to the fight against COVID-19....
A new study could lead to improved decision making in assigning treatments for children with the aggressive cancer rhabdomyosarcoma after revealing key genetic changes underlying development of the disease. In the largest and most comprehensive study of rhabdomyosarcoma to date, scientists found that specific genetic changes in tumours are linked to aggressiveness, early age of onset and location in the body....
Sinocompound Catalysts Co., Ltd has launched a new video series sharing its specialist catalyst expertise adding to its bank of educational materials. Titled ‘The essentials in a synthetic chemist’s toolbox’, the series was the idea and work of technical advisor, Dr Carin Seechurn. As a global provider of advanced homogeneous catalysts and ligands for pharmaceutical and fine chemical applications, Sinocompound is ideally placed to guide scientists through some of the challenges they may need to navigate...
Waters and The Bioprocessing Technology Institute (BTI) are engaging in data analytics research meant to eliminate a major bottleneck in the characterization of biopharmaceuticals, namely the identification and quantitation of complex biomolecules such as released N- and O- glycans and metabolites that influence therapeutic function. Isomerism of both glycans and metabolites is particularly troublesome and can be tackled using Waters’ advanced instruments....
SGD Pharma announces that its 20ml EasyLyo molded glass Type I vials are now available Ready-to-Use (RTU) in SG EZ-fill? Nest & Tub – an industry-recognized state-of-the-art secondary packaging format. Increased demand for parenteral drugs generated by the Covid-19 pandemic has resulted in additional pressures being placed on biopharmaceutical companies to accelerate their time-to-market....
Win 1 of 20 pipette kits to become a highly productive, low waste lab. Each kit includes: One VIAFLO electronic multichannel pipette of your choice, One case of ECO Rack GripTips (10 racks, sterile, filter), One reusable PopTop Base for use with ECO Racks and One single pipette charging stand...
Scientific Laboratory Supplies (SLS) has recently been accredited as a Living Wage Employer. The Living Wage commitment will see everyone working at SLS receive a minimum hourly wage of £9.50 in the UK, or £10.85 in London. Both rates are significantly higher than the government minimum for over 25s, which currently stands at £8.72 per hour...
The Government Chemist (GC), hosted at LGC, has published the results of a recent international ring trial on the determination of cannabidiol (CBD) - an uncontrolled cannabinoid- and controlled cannabinoids in consumer products such as food and cosmetics. Consumer CBD products have entered the UK market rapidly in a variety of forms, including food and cosmetics. CBD when used as an ingredient in food or cosmetic products must currently be free from controlled cannabinoids....
A shortlist of eye-catching images and videos has been drawn up for the RMS Scientific Imaging Competition – featuring as part of mmc2021. As a ‘sneak preview’, the RMS has put together a collage of all the shortlisted entries across the different categories (excluding video entries) ahead of mmc2021. The images and videos will be uploaded to an online gallery available to view from the start of the event...
AMSBIO invite the global research community to the 2021 annual meeting of the ISSCR, the leading professional organization of stem cell scientists, to discover how iPSCs and organoids can be used in COVID-19 drug discovery research. At this virtual meeting - Dr. Kazuo Takayama from the renowned Center for iPS Cell Research and application (CiRA) at Kyoto University will be giving a unique insight into his recent pioneering research...
The Maulide Group at the University of Vienna (Austria) describe how a devastating water leak in a nearby chemistry laboratory prompted them to search for alternative, water-free, options to Liebig condensers for refluxing. The group teamed up with Green Labs Austria to see if they could provide and share a more sustainable solution to water cooled refluxing in the lab....
The moisture determination of liquid soap is essential to ensure a product of the highest quality. If the moisture content is too high or too low, this can result in a low quality product and wastage can occur. In this application note we determine the moisture of liquid soap using Precisa’s XM60/EM120 Halogen moisture analyser...
In 2021, Eppendorf AG, the Hamburg life sciences company, is presenting its highly prestigious research prize for the 26th time. The independent Eppendorf Award Jury chaired by Prof. Reinhard Jahn announced Dr. Tanmay Bharat, Sir William Dunn School of Pathology, University of Oxford, United Kingdom as the winner of the Eppendorf Award for European Investigators 2021....
HORIBA announces its participation in a new consortium formed to accelerate the development of process analytical technologies (PAT) in cell and gene therapy manufacturing. HORIBA’s new A-TEEM™ Molecular Fingerprinting technology has shown great promise for fast QC/QA of complex biological systems and is a core technology being assessed for reducing batch failures and manufacturing costs, to enable faster time to market....
108Labs, a biotechnology and software company with a mission to invent disruptive cellular agriculture projects, has announced their focus on building and programming the world’s first autonomous Cellufacturing® facility and artificial intelligence platform for the production of cell-cultured human milk, in the birthplace of biosynthetic human milk, Hillsborough, North Carolina....
Binding Site is pleased to announce that the ground-breaking iStopMM (Iceland Screens, Treats or Prevents Multiple Myeloma) study has reached an important milestone, with the publication of a paper outlining the design and recruitment of this population-based screening study. The large-scale study – which includes over 80,000 individuals, more than half of the eligible population of Iceland...
Leading Drug Discovery Contract Research Organisation Sygnature Discovery has announced the set-up of a state-of-the-art Early Candidate Developability Screening Group. Located at its headquarters in Nottingham, UK, the new service line will expand on the company’s offerings to customers by bridging into formal preclinical drug development and paving the way for clinical trials...
Scientists have identified a new class of targeted cancer drugs that offer the potential to treat patients whose tumours have faulty copies of the BRCA cancer genes. The drugs, known as POLQ inhibitors, specifically kill cancer cells with mutations in the BRCA genes while leaving healthy cells unharmed. And crucially, they can kill cancer cells that have become resistant to PARP inhibitors – an existing treatment for patients with BRCA mutations....
As the COVID-19 pandemic continues, the worldwide search for an effective treatment is still ongoing. Remdesivir and GS-441524 are antiviral drugs that have been examined for the treatment of COVID-19 caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). Remdesivir is a nucleotide analogue inhibitor that can inhibit the replication of animal and human coronaviruses...
Australian National Phenome Centre Integrates Quantitative NMR and MS Assay Platform for Risk Assessment and Longitudinal Monitoring of Post-Acute COVID-19 Syndrome (PACS). A clinical research collaboration on COVID-19 pheno-conversion and subsequent pheno-reversion has discovered transient and persistent systemic changes of the molecular signatures in patient blood samples three months after the acute COVID-19 disease phase...
A new white paper, written by scientists at Liverpool ChiroChem (LCC), describes how the Asynt Illumin8 parallel photoreactor is being used to synthesise a range of new 2-Aryl N-Heterocycles. The discovery of a novel enantioselective synthetic pathway for reduction of pyridines to the corresponding chiral piperidines led to the formation of LCC in 2014. Since inception, LCC have enhanced their expertise enabling them to provide leading scientific organisations with access to chirally-pure compounds that play their part in small molecule drug discovery....
Whilst commonly used air displacement pipettes are highly accurate for most pipetting applications, their performance is adversely affected by the physical properties of the solutions handled, such as viscosity, volatility, surface tension and temperature. However, positive displacement pipettes like Gilson's ergonomic MICROMAN® E and Capillary Pistons (CPs) work differently, and volume delivery is unaffected by the nature of the sample...
The Native Antigen Company, part of LGC Clinical Diagnostics and one of the world’s leading suppliers of reagents that enables research into diagnostics and vaccines for emerging and endemic infectious diseases, won ‘The Best COVID-19 Responder’ at OBN 2020 Awards. The award recognises the Company’s outstanding contribution to the fight against COVID-19....